Abstract:
:We measured levels of basal and norepinephrine (NE) -induced melatonin release in cultured pineal bodies of rats just after and 2 days after irradiation (20 or 200 Gy) or sham-irradiation. On the day of irradiation, basal and NE-induced melatonin release were not affected by irradiation. Two days after irradiation, basal melatonin levels in both irradiated groups were significantly lower than those in control group, whereas NE-induced melatonin levels in the irradiated groups were higher than those in the control group. These results suggested that irradiation decreases basal melatonin synthesis in pineal glands but that melatonin response to NE is increased after irradiation.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Saito K,Shinohara K,Morofushi M,Funabashi T,Mitsushima D,Hata M,Matsubara S,Kimura Fdoi
10.1016/s0304-3940(00)00984-8keywords:
subject
Has Abstractpub_date
2000-04-21 00:00:00pages
93-6issue
1-2eissn
0304-3940issn
1872-7972pii
S0304-3940(00)00984-8journal_volume
284pub_type
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