The role of alpha-2 adrenoceptor subtype in the antiallodynic effect of intraplantar dexmedetomidine in a rat spinal nerve ligation model.

abstract：:Age dependent EEG signatures were detected in the EEG of 71 neonates of 28-100 weeks of conceptional age (CA). Using the new method presented, neonates were automatically classified in three age groups (28-35 weeks CA), (36-40 weeks CA) and (41-100 weeks CA). Analysis was performed employing relative distance function...

journal_title：Neuroscience letters

authors： Holthausen K,Breidbach O,Scheidt B,Frenzel J

更新日期：1999-06-25 00:00:00

abstract：:Pineal concentrations of 5-methoxytryptamine, 5-methoxytryptophol, 5-methoxyindole acetic acid and melatonin were determined using high performance liquid chromatography following administration of different monoamine oxidase (MAO) inhibitors (clorgyline, pargyline and deprenyl) to golden hamsters. Plasma concentratio...

journal_title：Neuroscience letters

authors： Raynaud F,Pévet P

更新日期：1991-02-25 00:00:00

abstract：:Recent investigations of rapid eye movement sleep (REMS) continuity have emphasized the importance of transitions both into and out of REMS. We have previously reported that, compared to Wistar rats (WIS), Wistar-Kyoto rats (WKY) responded to fear conditioning (FC) with more fragmented REMS. Gamma oscillations in the ...

journal_title：Neuroscience letters

authors： Laitman BM,Dasilva JK,Ross RJ,Tejani-Butt S,Morrison AR

更新日期：2011-04-08 00:00:00

abstract：:Periostin has dual roles as a multifunctional cytokine and an extracellular matrix protein that binds to several integrins on a variety of cells. This study evaluated whether the expression and cellular localization of periostin changes in the spinal cord of mice with experimental autoimmune encephalomyelitis (EAE), a...

journal_title：Neuroscience letters

authors： Choi Y,Kim J,Ahn M,Shin T

更新日期：2020-01-10 00:00:00

abstract：:The human hypothalamus is at the center of the human limbic system anatomically and physiologically. The hypothalamus plays pivotal roles in controlling autonomic responses and instinctive behaviors such as regulating fear, aggression, learning, feeding behavior, circadian rhythm, and reproductive activities. The deta...

journal_title：Neuroscience letters

authors： Kamali A,Ghazi Sherbaf F,Rahmani F,Khayat-Khoei M,Aein A,Gandhi A,Shah EG,Sair HI,Riascos RF,Esquenazi Y,Zhu JJ,Keser Z,Hasan KM

更新日期：2020-05-29 00:00:00

abstract：:We examined age effects on Movement related potentials (MRPs) in 13 young (mean age = 29.3 years) and 13 old (mean age = 67.2 years) normal adults in right, left and bimanual self-paced button press conditions. Both the groups generated a slowly rising readiness potential (RP) at about 1000 ms, a negative shift (NS') ...

journal_title：Neuroscience letters

authors： Singh J,Knight RT,Woods DL,Beckley DJ,Clayworth C

更新日期：1990-10-30 00:00:00

abstract：:Vascular alterations of peripheral nerves occuring after mechanical injury or in metabolic disorders are well described. It is thought that vascular endothelial growth factor (VEGF), a potent growth factor for angiogenesis, also plays an important role for regeneration of nervous tissue. We used a rat model of type I ...

journal_title：Neuroscience letters

authors： Samii A,Unger J,Lange W

更新日期：1999-03-12 00:00:00

abstract：:Cultured embryonic mouse olfactory bulb cells formed asymmetric, symmetric, axodendritic, and dendrodendritic synapses. These neurons contained electron lucent, dense core, and coated vesicles. Dense core and coated vesicles had an average diameter of 71 and 80 nm, respectively. Two statistically different populations...

journal_title：Neuroscience letters

authors： Fracek SP Jr,Guo L,Schafer R

更新日期：1994-04-11 00:00:00

abstract：:We carried out an immunohistochemical investigation of the spinal cords of 15 patients with sporadic amyotrophic lateral sclerosis (ALS), using antibodies to inducible nitric oxide synthase (iNOS) and nitrotyrosine; our purpose was to search for a possible role of increased oxidative damage in the motor system that ma...

journal_title：Neuroscience letters

authors： Sasaki S,Shibata N,Komori T,Iwata M

更新日期：2000-09-08 00:00:00

abstract：:Despite much study since its discovery in 1995, the effects of orphanin FQ/nociceptin (OFQ/N), the endogenous ligand of the 'orphan' opioid receptor, on nociceptive sensitivity remain unclear. Different laboratories have variously reported hyperalgesic, analgesic, anti-analgesic or no effect of the peptide on thermal ...

journal_title：Neuroscience letters

authors： Mogil JS,Nessim LA,Wilson SG

更新日期：1999-02-19 00:00:00

abstract：:Transition of the cellular responsiveness to a cholinergic stimulation during a prolonged stimulation with acetylcholine (ACh) of adrenal chromaffin cells was studied by directly monitoring the secretory process in cell bed perfusion experiments. A pulsatile injection of hexamethonium during the prolonged stimulation ...

journal_title：Neuroscience letters

authors： Ohara-Imaizumi M,Kumakura K

更新日期：1986-10-08 00:00:00

abstract：:The acute reactions of vasoactive intestinal polypeptide (VIP)-containing neurons in the myenteric plexus of the rat jejunum in response to circumferential clamping or transection/reanastomosis were evaluated in a detailed time course of up to ten days. Whereas in sham-operated controls VIP immunostaining was confined...

journal_title：Neuroscience letters

authors： Trudrung P,Waldner H,Sklarek J,Nitsch C

更新日期：1990-02-16 00:00:00

abstract：:Highly purified and metabolically viable gamma-aminobutyric acid (GABA)ergic and cholinergic synaptosomes were prepared from mammalian brain using antisera raised against glutamate decarboxylase and choline acetyltransferase respectively. These antisera appear to recognise specific outwardly facing components of GABAe...

journal_title：Neuroscience letters

authors： Docherty M,Bradford HF,Wu JY

更新日期：1987-10-16 00:00:00

abstract：:It has been shown that the incidence of cognitive impairment increases with the severity of chronic kidney disease (CKD). A previous study has demonstrated that hippocampal oxidative stress contributes to cognitive dysfunction in CKD model mice. Endoplasmic reticulum (ER) stress is thought to contribute significantly ...

journal_title：Neuroscience letters

authors： Kosuge Y,Osada N,Shimomura A,Miyagishi H,Wada T,Ishige K,Shimba S,Ito Y

更新日期：2018-06-11 00:00:00

abstract：:Recently, there has been a lot of interest in the neuroimaging community in exploring fMRI time-series measures of local neuronal activity and excitation/inhibition (E/I) balance in the brain. In this preliminary study we probed the sensitivity of widely used sample entropy (SE) measure at multiple scales to controlle...

journal_title：Neuroscience letters

authors： Maltbie EA,Howell LH,Sun PZ,Miller R,Gopinath KS

更新日期：2020-05-29 00:00:00

abstract：:The nitric oxide synthase (NOS) inhibitor L-nitroarginine methyl ester has been found to exhibit antinociceptive activity in a rat model of pain [Kitto, K.F. et al., Neurosci. Lett., 148 (1992) 1-5; Lee, J.H. et al., NeuroReport, 3 (1992) 841-844; Moore, P.K. et al., Br. J. Pharmacol., 102 (1991) 198-202]. We investig...

journal_title：Neuroscience letters

authors： Lam HH,Hanley DF,Trapp BD,Saito S,Raja S,Dawson TM,Yamaguchi H

更新日期：1996-06-07 00:00:00

abstract：:Somatostatin and several analogues were injected into rat striatum and their effects on dopamine, serotonin and their metabolites were examined at 1 h. Somatostatin induced a dose-dependent increase in dopamine turnover in the ipsilateral striatum accompanied by a reduction in turnover on the contralateral side. There...

journal_title：Neuroscience letters

authors： Beal MF,Martin JB

更新日期：1984-02-24 00:00:00

abstract：:The angular distribution of mitotic spindle fibers has been studied in the telencephalic ventricular zone (VZ) of mouse embryos and has been found to be monophasic and invariant during the early cortical histogenesis both in the normal and in a reeler embryo. This observation suggests that the orientation of mitotic s...

journal_title：Neuroscience letters

authors： Landrieu P,Goffinet A

更新日期：1979-06-01 00:00:00

abstract：:The discharge of 38 tibialis anterior (TA) muscle spindle endings was recorded at rest and during isometric voluntary contraction of the ankle joint in eight healthy human subjects. With the ankle joint in 110 degrees plantarflexion, 24 endings (61%) were tonically active in the resting subject. During weak voluntary ...

journal_title：Neuroscience letters

authors： Nielsen J,Nagaoka M,Kagamihara Y,Kakuda N,Tanaka R

更新日期：1994-04-11 00:00:00

abstract：:Normal rats tend to respond to a sudden burst of noise or flash of light with slightly less startle when they are engaged in active behaviour at the time of presentation. This effect is vastly more pronounced in animals with lesions of the superior colliculus. These results are taken as support for a theory implicatin...

journal_title：Neuroscience letters

authors： Goodale MA,Milner AD,Rose JE

更新日期：1975-12-01 00:00:00

abstract：:Aging is associated with cognitive deterioration. A recent study showed two polymorphisms (rs505058 in LMNA and rs11622883 near a SERPINA13 gene), identified in a genome-wide association study of late-onset Alzheimer's disease, to be associated with cognitive function (Mini Mental State Examination) in a UK elderly po...

journal_title：Neuroscience letters

authors： Yeh HL,Hou SJ,Yen FC,Hong CJ,Liou YJ,Yang AC,Liu ME,Tsai SJ

更新日期：2011-10-17 00:00:00

abstract：:Centrally formed acetaldehyde has proven to be responsible for several psychopharmacological effects induced by ethanol. In addition, it has been suggested that the cAMP-PKA signaling transduction pathway plays an important role in the modulation of several ethanol-induced behaviors. Therefore, we hypothesized that ac...

journal_title：Neuroscience letters

authors： Tarragon E,Baliño P,Aragon CM

更新日期：2014-09-19 00:00:00

abstract：:Plasma renin activity (PRA) was determined in plasma samples obtained approximately at 6-min intervals during consecutive non-rapid eye movement sleep (NREMS) and rapid eye movement sleep (REMS) periods in rats chronically implanted with EEG electrodes, a brain thermistor, and an intracardiac catheter. PRA was low in ...

journal_title：Neuroscience letters

authors： Obál F Jr,Beranek L,Brandenberger G

更新日期：1994-09-26 00:00:00

abstract：:Employing double anterograde axonal tracing in combination with intracortical microstimulation, we examined the distribution patterns of corticosubthalamic inputs from forelimb representations of the dorsal (PMd) and ventral (PMv) divisions of the premotor cortex in the macaque monkey. The inputs from the PMd and PMv ...

journal_title：Neuroscience letters

authors： Nambu A,Tokuno H,Inase M,Takada M

更新日期：1997-12-12 00:00:00

abstract：:The effect of the R(-) and S(+) isomers of 3,4-methylenedioxyamphetamine (MDA) and its N-methyl analog 3,4-methylenedioxymethamphetamine (MDMA) on [3H]inositol monophosphate accumulation was studied in cells expressing either 5-HT2A or 5-HT2C receptors. The isomers of MDA produced a concentration dependent increase in...

journal_title：Neuroscience letters

authors： Nash JF,Roth BL,Brodkin JD,Nichols DE,Gudelsky GA

更新日期：1994-08-15 00:00:00

abstract：:125I-Staphylococcal protein A was used to visualize immunoreactive cell antigen in rat brain and pituitary by autoradiography. Autoradiograms of rat brain sections generated with 125I-protein A were clear and showed low background signals. We were able to visualize neural structures containing tyrosine hydroxylase or ...

journal_title：Neuroscience letters

authors： Correa FM,Guilhaume SS,Saavedra JM

更新日期：1988-06-29 00:00:00

abstract：:There is a growing body of evidence that the ventromedial prefrontal cortex (VMPFC) is implicated in the new learning of visual items. Little is known, however, as to the involvement of that portion of the prefrontal cortex in the learning of temporal and spatial relationship of those items. The aim of the present stu...

journal_title：Neuroscience letters

authors： Szatkowska I,Szymańska O,Grabowska A

更新日期：2004-07-01 00:00:00

abstract：:A random sample of 60 late-onset Alzheimer's disease (AD) cases from a population-based study were apolipoprotein E (apoE) genotyped and clinically examined with a 3-year interval. The epsilon 4 allele carriers had a significantly lower age of disease onset compared to non-epsilon 4 carriers. However, no significant d...

journal_title：Neuroscience letters

authors： Basun H,Grut M,Winblad B,Lannfelt L

更新日期：1995-01-02 00:00:00

abstract：:The present study examined perception of individual finger forces during multi-finger force production tasks. In an ipsilateral force matching paradigm, 12 healthy subjects were instructed to produce a reference force pre-determined at 30% MVC of involved fingers (varying from 1 to 4 fingers, visual feedback of total ...

journal_title：Neuroscience letters

authors： Li S

更新日期：2006-12-06 00:00:00

abstract：:Methamphetamine (METH) may cause long‒lasting neurotoxic effects and cognitive impairment. On the other hand, the ovarian hormones estrogen and progesterone have neuroprotective effects. In the current study, we aimed to examine the effects of estrogen and progesterone on anxiety‒like behavior and neuronal damage in M...

journal_title：Neuroscience letters

authors： Ghazvini H,Tirgar F,Khodamoradi M,Akbarnejad Z,Rafaiee R,Seyedhosseini Tamijani SM,Asadi-Shekaari M,Esmaeilpour K,Sheibani V

更新日期：2021-01-19 00:00:00