Serotonin reduces synaptic excitation of principal cells in the superficial layers of rat hippocampal-entorhinal cortex combined slices.

abstract：:In recent years, several attempts have been made to identify biochemical and/or genetic markers which might have diagnostic and prognostic uses for Alzheimer's disease (AD). To look for possible new blood markers, a longitudinal study was carried out in our Central Nervous System Biomedical Research Center between Oct...

journal_title：Neuroscience letters

authors： Lombardi VR,Cacabelos R

更新日期：1999-01-22 00:00:00

abstract：:Hearing loss is a common sensory disorder that affects more than 360 million people worldwide, and is primarily caused by the loss of hair cells (HCs). Ototoxic drugs, viral infections, genetic predisposition, aging or noise all damage HCs. 3β-hydroxysteroid-Δ24 reductase (DHCR24), one enzyme in the cholesterol biosyn...

journal_title：Neuroscience letters

authors： Tian KY,Chang HM,Wang J,Qi MH,Wang WL,Qiu Y,Liang K,Chen FQ,Zha DJ,Qiu JH

更新日期：2019-07-27 00:00:00

abstract：:The 5,10-methylenetetrahydrofolate reductase (MTHFR) gene has been reported to be a candidate gene for susceptibility to Parkinson's disease (PD), but results of different studies are conflicting. Here, we conducted a meta-analysis of published case-control studies to evaluate the association between MTHFR C677T and A...

journal_title：Neuroscience letters

authors： Liu L,Zhang L,Guo L,Yu Q,Li H,Teng J,Xie A

更新日期：2018-01-01 00:00:00

abstract：:Stereotaxic injections of ibotenic acid (IBO) and kainic acid (KA) into either the dorsal hippocampus or the lateral cerebroventricle were performed in order to determine the relative potencies of the drugs and the vulnerability of different hippocampal cell types to their neurotoxic action, IBO was found to be approx...

journal_title：Neuroscience letters

authors： Köhler C,Schwarcz R,Fuxe K

更新日期：1979-12-01 00:00:00

abstract：:Rim is a multi-domain, active zone protein that regulates exocytosis and is implicated in vesicle priming and presynaptic plasticity. We recently demonstrated that synaptic defects associated with loss of Caenorhabditis elegans Rim (termed UNC-10) are accompanied by a reduction in docked vesicles adjacent to the presy...

journal_title：Neuroscience letters

authors： Gracheva EO,Hadwiger G,Nonet ML,Richmond JE

更新日期：2008-10-24 00:00:00

abstract：:A method for the histochemical demonstration of cells with the capacity to synthesize the enzyme GABA-transaminase is described. Intraventricular injection of ethanolamine-O-sulfate irreversibly inhibits brain GABA-transaminase activity. Within 17 h after the injection sufficient new enzyme is synthesized to allow his...

journal_title：Neuroscience letters

authors： Vincent SR,Kimura H,McGeer EG

更新日期：1980-03-01 00:00:00

abstract：:When standing quietly, human upright stance is typically approximated as a single segment inverted pendulum. In contrast, investigations which perturb upright stance with support surface translations or visual driving stimuli have shown that the body behaves like a two-segment pendulum, displaying both in-phase and an...

journal_title：Neuroscience letters

authors： Creath R,Kiemel T,Horak F,Peterka R,Jeka J

更新日期：2005-03-29 00:00:00

abstract：:Field potentials were recorded with electrodes implanted in various cortical areas while a naive monkey was learning reaction time hand movements with complex tone. When cortical surface-negative, depth-positive potential (at a latency of about 80 ms after a stimulus onset) appeared in the rostral bank of the inferior...

journal_title：Neuroscience letters

authors： Gemba H,Miki N,Sasaki K

更新日期：1995-05-05 00:00:00

abstract：:It has been generally suggested that chewing produces an enhancing effect on cognitive performance-related aspects of memory by the test battery. Furthermore, recent studies have shown that chewing is associated with activation of various brain regions, including the prefrontal cortex. However, little is known about t...

journal_title：Neuroscience letters

authors： Hirano Y,Obata T,Kashikura K,Nonaka H,Tachibana A,Ikehira H,Onozuka M

更新日期：2008-05-09 00:00:00

abstract：:The effect of acute phenylethanolamine-N-methyltransferase (PNMT) inhibition on rat brain catecholamine concentrations was studied. All PNMT inhibitors tested were effective in depleting hypothalamic and brain stem epinephrine. Norepinephrine concentrations were unaffected; however, dopamine levels were increased in a...

journal_title：Neuroscience letters

authors： Mefford IN,Roth KA,Barchas JD

更新日期：1980-10-20 00:00:00

abstract：:Estrogen was shown to promote neuronal survival against several neurotoxic insults including β-amyloid (Aβ). The proposed mechanism includes the activation of the mitogen activated protein kinase/extracellular signal-regulated kinase (Mapk/Erk), phosphatidylinositol 3-kinase/Akt pathways and the upregulation of antiap...

journal_title：Neuroscience letters

authors： Mateos L,Persson T,Katoozi S,Gil-Bea FJ,Cedazo-Minguez A

更新日期：2012-01-11 00:00:00

abstract：:Direct projections from the A1/C1 catecholaminergic cell group in the caudal ventrolateral medulla oblongata to neurons containing vasopressin (VP) in the supraoptic nucleus (SON) were studied electron microscopically by a double-labeling technique which combines anterograde tracing after injection of wheat germ agglu...

journal_title：Neuroscience letters

authors： Shioda S,Shimoda Y,Nakai Y

更新日期：1992-12-14 00:00:00

abstract：:The comorbidity between migraine and depression not only provides a major treatment challenge, but also represents a heavy burden on society. However, the relationship between depression and migraine and their molecular biological mechanisms remain unclear. This study investigated the effects of depression elicited by...

journal_title：Neuroscience letters

authors： Zhang M,Dai W,Liang J,Chen X,Hu Y,Chu B,Pan M,Dong Z,Yu S

更新日期：2013-09-13 00:00:00

abstract：:An antiserum to choline acetyltransferase, partially purified from bovine brain (anti-ChAT 1), when incubated with synaptosomes prepared from rat cerebral cortex in the presence of complement caused release of 10% of lactate dehydrogenase and 27% of ChAT. Sodium-dependent uptake of choline was totally abolished. Simil...

journal_title：Neuroscience letters

authors： Docherty M,Bradford HF

更新日期：1986-10-08 00:00:00

abstract：:The purpose of this study was to determine whether the loss of protein kinase C (PKC) from adrenal chromaffin cells affected the enhancement of high K(+)- and forskolin-stimulated tyrosine hydroxylase (tyrosine 3-monooxygenase, EC 1.14.16.2) activity observed in cells treated with insulin-like growth factor-I (IGF-I)....

journal_title：Neuroscience letters

authors： Dahmer MK

更新日期：1995-12-08 00:00:00

abstract：:beta-Bungarotoxin (BuTx)-binding cells were immunocytochemically examined in the developing rat cerebellum. The tissue was incubated with BuTx and then immunostained with antiserum against its toxoid. On postnatal day 6, only Golgi cells were positive for immunoreaction. Immunoreactive Golgi cells were reduced in numb...

journal_title：Neuroscience letters

authors： Katoh-Semba R,Semba R,Kashiwamata S

更新日期：1987-04-23 00:00:00

abstract：:Glufosinate ammonium, a structural analogue of glutamate, is an active herbicidal ingredient. The neuronal activities of this compound were investigated by use of a microdialysis system that allowed us to measure nitric oxide production in the rat cerebellum in vivo. Kainate (0.3-30 nmol/10 microliter), N-methyl-D-asp...

journal_title：Neuroscience letters

authors： Nakaki T,Mishima A,Suzuki E,Shintani F,Fujii T

更新日期：2000-09-01 00:00:00

abstract：:Ethanol withdrawal is a serious clinical problem owing in part to over stimulation of ionotropic glutamate receptors in the brain and is linked to elevated oxidative damage. In this study, we tested the hypothesis that lipid peroxidation is elevated in the brain tissue of rats fed an ethanol-containing diet for 6 week...

journal_title：Neuroscience letters

authors： Milne GL,Morrow JD,Picklo MJ Sr

更新日期：2006-09-25 00:00:00

abstract：:Although the guinea pig is used widely in experimental medical research, including in studies on micturition control, the spinal origin of preganglionic parasympathetic bladder and somatic external urethral sphincter motoneurons is not known. In the male guinea pig using wheat germ agglutinin-conjugated horseradish pe...

journal_title：Neuroscience letters

authors： Kuipers R,Izhar Z,Gerrits PO,Miner W,Holstege G

更新日期：2004-05-13 00:00:00

abstract：:The ganglion cell density of the quail's retina was studied in sections and whole mounts. Two regions of high ganglion cell density were found, corresponding to an afoveate area centralis and an area dorsalis. Oil droplets were found to be isotropically distributed throughout the retina. It is proposed that the signif...

journal_title：Neuroscience letters

authors： Budnik V,Mpodozis J,Varela FJ,Maturana HR

更新日期：1984-09-28 00:00:00

abstract：:Morphine injections in 16-day-old rats caused an increase in norepinephrine concentration in both superior cervical ganglion and iris after 1 h. Although the increase in the ganglion was blocked by naloxone pretreatment, the increase in the iris was not prevented. The morphine-induced increase did not require the pres...

journal_title：Neuroscience letters

authors： Mattio TG,Kirby ML

更新日期：1983-09-09 00:00:00

abstract：:The p53 gene is mutated in pluripotential human neuroectodermal tumor DAOY cells which express both glial and neuronal markers. In most cells, nuclear m-p53 immunostaining was intense while cytoplasmic glial specific proteins (GSPs) were present at low levels. Conversely, glial fibrillary acidic protein (GFAP) and glu...

journal_title：Neuroscience letters

authors： U HS,Banaie A,Rigby L,Chen J

更新日期：1998-03-06 00:00:00

abstract：:The kinetics of the association and dissociation of the tritium-labeled selective and potent dopamine transporter inhibitor N-(3-iodoprop-2E-enyl)-2beta-carbo-[3H]methoxy-3beta-(4'-methylphenyl)nortropane ([3H]PE2I) with the transporter of mouse striatal membranes was studied. The analysis revealed that the specific b...

journal_title：Neuroscience letters

authors： Stepanov V,Järv J

更新日期：2006-12-27 00:00:00

abstract：:It was accepted for a long time that in mammals there is only retinofugal neuronal connection between the eye and the pineal body (PB). In our previous paper we described that nerve cells were present in hamster PB and these neurons could establish a reverse connection with the retina through a transsynaptic pathway. ...

journal_title：Neuroscience letters

authors： Csáki Á,Vereczki V,Lukáts Á,Boldogkői Z,Sebestyén A,Puskár Z,Köves K

更新日期：2018-02-05 00:00:00

abstract：:Three variations of the in vitro neonatal rat spinal cord preparation were used to investigate motor responses to stimulation of the ventrolateral funiculus (VLF). In a partially hemisected spinal cord preparation, stimuli elicited frequency-dependent activity in lumbar ventral roots that outlasted the stimulus train ...

journal_title：Neuroscience letters

authors： Magnuson DS,Schramm MJ,MacLean JN

更新日期：1995-06-09 00:00:00

abstract：:An optimized clinical functional magnetic resonance imaging (fMRI) protocol with a total scanning time of 8 min is presented that localizes Broca's and Wernicke's areas robustly and determines hemispheric dominance. Language function was visualized using two different sentence generation (SG) and word generation (WG) ...

journal_title：Neuroscience letters

authors： Stippich C,Mohammed J,Kress B,Hähnel S,Günther J,Konrad F,Sartor K

更新日期：2003-07-31 00:00:00

abstract：:In this study we examined the presence of dopamine D1 receptors in monkey amniotic epithelial cells (MAEC) using RT-PCR and radioligand binding experiments. We found that MAEC express D1 receptor mRNA that is having 99% homology with human dopamine D1 receptors. Saturation binding studies using [3H]SCH-23390 showed a ...

journal_title：Neuroscience letters

authors： Elwan MA,Ishii T,Ono F,Sakuragawa N

更新日期：1999-02-26 00:00:00

abstract：:The localization of amyloid beta protein (A beta), A beta 40, A beta 42, and transthyretin (TTR) was investigated immunohistochemically in the autopsied human kidney, using polyclonal antibodies against TTR, A beta and C-terminal end-specific antibodies against A beta 40 and 42. Immunoreactivities of A beta and A beta...

journal_title：Neuroscience letters

authors： Tsuzuki K,Fukatsu R,Hayashi Y,Yoshida T,Sasaki N,Takamaru Y,Yamaguchi H,Tateno M,Fujii N,Takahata N

更新日期：1997-02-07 00:00:00

abstract：:To study the neuronal mechanism of a conditioned taste-aversion (CTA) learning in the pond snail Lymnaea stagnalis, we examined the synaptic connection between the neuron 1 medial (N1M) cell and the cerebral giant cell (CGC), the former is an interneuron in central pattern generator for the feeding response and the la...

journal_title：Neuroscience letters

authors： Kojima S,Nanakamura H,Nagayama S,Fujito Y,Ito E

更新日期：1997-07-25 00:00:00

abstract：:The microscopic distribution of omega 3 (peripheral type benzodiazepine) binding sites in sections from normal and ischaemic rat brain has been determined by emulsion autoradiography with the photoaffinity ligand [3H]PK 14105. In the normal rat brain, high densities of omega 3 sites were present in the ependymal cells...

journal_title：Neuroscience letters

authors： Benavides J,Dubois A,Gotti B,Bourdiol F,Scatton B

更新日期：1990-06-22 00:00:00