Abstract:
:The microscopic distribution of omega 3 (peripheral type benzodiazepine) binding sites in sections from normal and ischaemic rat brain has been determined by emulsion autoradiography with the photoaffinity ligand [3H]PK 14105. In the normal rat brain, high densities of omega 3 sites were present in the ependymal cells, the apical pole of the secretory cells in the choroid plexus and astrocyte-like cells in the outer cellular layer of the olfactory bulb. In ischaemic brain lesions caused by middle cerebral artery occlusion in spontaneously hypertensive rats or in spontaneous ischaemic and haemorrhagic lesions in spontaneously hypertensive stroke-prone rats, the proliferating omega 3 sites were associated with reactive glial cells and macrophages.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Benavides J,Dubois A,Gotti B,Bourdiol F,Scatton Bdoi
10.1016/0304-3940(90)90424-8subject
Has Abstractpub_date
1990-06-22 00:00:00pages
32-8issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(90)90424-8journal_volume
114pub_type
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