Abstract:
:By combining techniques designed to increase the amount of horseradish peroxidase (HRP) available for transport and to improve the sensitivity of the reaction for detecting HRP, we have produced an anterograde HRP technique suitable for labeling sparse efferent projections. The efficacy of this light, microscopic technique was demonstrated by lebeling the hippocampal commissural and crossed temporo-ammonic projections to the dentate gyrus of the rat.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
West JR,Black AC Jrdoi
10.1016/0304-3940(79)91476-9subject
Has Abstractpub_date
1979-04-01 00:00:00pages
35-40issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(79)91476-9journal_volume
12pub_type
杂志文章abstract::The effects of bilateral cut of the stria terminalis (ST) on the dosage of estradiol benzoate (EB) needed to induce the lordosis reflex in the ovariectomized female rat were examined. Seven different doses ranging 0.5-20 micrograms were given s.c. in oil, daily for 2 days in a counterbalanced order, at 3-week interval...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(94)11173-g
更新日期:1995-01-23 00:00:00
abstract::Intolerance of uncertainty (IU), or the increased affective response to situations with uncertain outcomes, is an important component process of anxiety disorders. Increased IU is observed in panic disorder (PD), obsessive compulsive disorder (OCD) and generalized anxiety disorder (GAD), and is thought to relate to dy...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.10.030
更新日期:2008-01-10 00:00:00
abstract::Melatonin is the principle hormonal product of the pineal gland. It is secreted with a robust daily rhythm, peaking near the middle of the night. During the daytime, concentrations remain very low, as exposure to light robustly suppresses its secretion. The regulation of melatonin by light is well-characterized, but a...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2013.03.021
更新日期:2013-05-10 00:00:00
abstract::We examined the somatotopical relationship between cortical activity and sensory stimulation of reflex areas in reflexology using functional magnetic resonance imaging. Three reflex areas on the left foot, relating to the eye, shoulder, and small intestine were stimulated during the experiment. A statistical analysis ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2008.10.022
更新日期:2008-12-19 00:00:00
abstract::The type of glass used to fabricate patch pipettes influences the kinetic properties of single-channel currents activated by acetylcholine in Xenopus myocytes. In patches formed with hard glass pipettes, the opening rate decreased in a time-dependent manner. Such decrease was most pronounced for the low-conductance ch...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90312-6
更新日期:1988-05-16 00:00:00
abstract::Assessing the result of conceptual change (i.e., whether an individual has come to correctly understand a science concept) is important in science education, however traditional assessment methods lack objectivity. In this study, permutation entropy (PE) based complexity, a kind of entropy used to quantify the complex...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2019.02.015
更新日期:2019-04-23 00:00:00
abstract::The prioritized processing of threat is suggested to be motivated by anxiety, regulated by the parasympatheticus, and biased to the right hemisphere. However, according to an anterior dimensional model of negative affect this is unlikely to be true when threat is of social origin. Social threat is communicated by the ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(01)02558-7
更新日期:2002-02-15 00:00:00
abstract::In vitro pituitary adenylate cyclase activating polypeptide (PACAP) induces the expression of brain-derived neurotrophic factor (BDNF) via its specific receptor PAC1. Since BDNF has been implicated in learning paradigms and mice lacking functional PAC1 have deficits in hippocampus-dependent associative learning, we in...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2004.01.030
更新日期:2004-04-22 00:00:00
abstract::Substance P (SP) immunocytochemistry and receptor autoradiography were used to define the innervation of the equine synovial membrane of joints equivalent to the wrist and knuckle of man. SP-immunoreactive fibers were mainly concentrated around blood vessels in the subsynovial layer, although not exclusively, while in...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(93)90861-e
更新日期:1993-12-24 00:00:00
abstract::Tryptophan hydroxylase 2 (TPH2) catalyzes the rate-limiting step in the synthesis of brain serotonin (5-HT). In a previous report, a single nucleotide polymorphism in mTph2 (C1473G) reduced 5-HT synthesis by 55%. Mouse strains expressing the 1473C allele, such as C57Bl/6, have higher 5-HT synthesis rates than strains ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2010.06.035
更新日期:2010-08-30 00:00:00
abstract::A predominant form of the GABAA/benzodiazepine receptor-Cl- channel complex is believed to consist of three different 48-55 kDa subunits (alpha, beta, gamma) with unknown stoichiometry. Plasmids containing the rat GABAA receptor cDNAs coding for alpha 1, beta 2, and gamma 2 were co-transfected, along with a plasmid en...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(93)90323-d
更新日期:1993-04-30 00:00:00
abstract::In this study we determined that cholinergic neurons from the lateral dorsal tegmental (LDT) and peribrachial pontine region (PPG) innervate the medial pontine reticular formation (medial PRF), a region involved in the generation of REM sleep. Wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) was injec...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90625-8
更新日期:1988-12-19 00:00:00
abstract::A push-pull perfusion technique was used to sample third ventricular cerebrospinal fluid (CSF) in the conscious rat. Ventricular perfusate contained significant quantities of vasopressin and oxytocin, 13.1 and 4.5 pg/ml, respectively. Vasopressin and oxytocin levels were stable over a 3 h perfusion period. High sodium...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(82)90329-9
更新日期:1982-04-26 00:00:00
abstract::To examine postural stability of the head, slow, undetectable rotations of small amplitude were imposed about a vertical axis while human subjects maintained a stationary body. Six normal subjects were used. The rotations were imposed through an elastic linkage, and lasted 4 s. The amplitude of head rotation was small...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(96)12914-1
更新日期:1996-08-23 00:00:00
abstract::Recently, research on lateralized event related potentials (ERPs) in response to irrelevant distractors has revealed that angry but not happy schematic distractors capture spatial attention. Whether this effect occurs in the context of the natural expression of emotions is unknown. To fill this gap, observers were ask...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2016.11.055
更新日期:2017-01-10 00:00:00
abstract::Reactive oxygen species and inflammatory signaling have been identified as pivotal pathophysiological factors contributing to epileptogenesis. Considering the development of combined anti-inflammatory and antioxidant treatment strategies with antiepileptogenic potential, a characterization of the time course of microg...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2015.05.041
更新日期:2015-07-10 00:00:00
abstract::Freshwater clams are a popular health food in Asia and are traditionally used to prevent hepatic inflammation. Freshwater clam extract (FCE) inhibits inflammatory responses in activated macrophages by reducing the activation of mitogen-activated protein kinase and nuclear factor kappa-light-chain-enhancer of activated...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2017.01.051
更新日期:2017-03-06 00:00:00
abstract::We have looked at the effect of synthetic mu-conotoxin GIIIA, a selective blocker of muscle Na channels, on various parameters of synaptic transmission at the frog sartorius nerve-muscle preparation. We found that 5 microM mu-conotoxin consistently blocked muscle action potentials, but had no effect on nerve action po...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(93)90745-7
更新日期:1993-07-23 00:00:00
abstract::We recorded epidural event-related potentials (ERPs) from the auditory cortex in anesthetized rats when pitch-deviant tones were presented in a homogeneous series of standard tones (oddball condition). Additionally, deviant tones were presented without standard tones (deviant-alone condition). ERPs to deviant tones in...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(98)00330-9
更新日期:1998-05-22 00:00:00
abstract::The Amphibalanus amphitrite barnacle is a sessile marine crustacean and a major constituent of benthic as well as intertidal communities. A. amphitrite is also an important component of biofouling on artificial substrates. The role of nitric oxide (NO) was recently observed in the settlement of this species. In this w...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2013.09.041
更新日期:2013-10-25 00:00:00
abstract::The present study seeked to determine whether the neurodegenerative and cognitive alterations in aged apolipoprotein E-deficient mice are differentially reversed by transgenic overexpression of human apolipoprotein-E3 vs. apolipoprotein-E4 in the background of deficient endogenous apolipoprotein E. These studies showe...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(99)00243-8
更新日期:1999-04-23 00:00:00
abstract::Electrical high frequency deep brain stimulation (DBS) of the globus pallidus internus (GPi) or the subthalamic nucleus (STN) has dramatic beneficial motor effects in advanced Parkinson's disease (PD). However, the mechanisms underlying these clinical results remain unclear. It is proposed that the gamma-aminobutyric ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2004.08.050
更新日期:2004-11-23 00:00:00
abstract::Previous studies showed that adenosine receptors of the temporal and frontal cortices were not affected in Alzheimer's disease (AD). Here, we assessed the specific binding of [3H]cyclohexyladenosine to adenosine1 (A1) receptors in hippocampus from AD subjects and age-matched controls. By both particulate membrane and ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(90)90641-l
更新日期:1990-10-16 00:00:00
abstract::Alpha-synuclein has been implicated in the pathology of certain neurodegenerative diseases, including Parkinson disease (PD) and dementia with Lewy bodies (LBs). Overexpression of human alpha-synuclein in neuronal cells reduces cell viability, but the precise cellular and molecular mechanisms remain poorly understood....
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.02.025
更新日期:2007-04-18 00:00:00
abstract::The ability of increases in extracellular potassium ([K+]o) and/or decreases in extracellular calcium ([Ca2+]o) to induce epileptiform activity in hippocampal slices was studied by systematically varying [K+]o and [Ca2+]o. Slices prepared from kindled rats, both 1 week and 1 month after the last kindled seizure, showe...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90478-8
更新日期:1988-06-17 00:00:00
abstract::In decerebrated rabbits, reflexes were evoked in medial gastrocnemius motoneurones by mechanical stimulation of the heel, using four pinch strengths from 183 (innocuous) to 4577 (noxious) mN. The alpha(2)-adrenoceptor antagonist idazoxan (1-156 microg intrathecal (i.th.) significantly increased responses to pinch stre...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(01)02005-5
更新日期:2001-08-10 00:00:00
abstract::In previous studies, chronic low-dose methylphenidate (MPH) administration during early development has been shown to increase emotional responding in adulthood. However, most studies employed male subjects, which generally show enhanced fear relative to females in laboratory tests of anxious behaviors. The present st...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2011.03.080
更新日期:2011-05-27 00:00:00
abstract::Activin A levels are elevated in the cerebrospinal fluid (CSF) of patients with meningitis and in the sera of patients with sepsis. The source(s) of the elevated concentrations of activin A in CSF and serum have not yet been discovered. Here we demonstrate that primary mouse microglial cells and peritoneal macrophages...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2006.11.065
更新日期:2007-02-21 00:00:00
abstract::A fundamental question in human sexuality regards the neural substrate underlying sexually-arousing representations. Lesion and neuroimaging studies suggest that dorsolateral pre-frontal cortex (DLPFC) plays an important role in regulating the processing of visual sexual stimulation. The aim of this Functional Near-In...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.01.058
更新日期:2007-04-06 00:00:00
abstract::In order to assess functional skills of older adults, both timed up and go (TUG) test and gait speed (GS) test are well validated concerning their predictive capacities. However, the question remains unclear which one of these tests represents better the whole physical performance of older adults. The aim of this stud...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2014.06.014
更新日期:2014-08-08 00:00:00