Thermoreceptive neurons in the dorsal portion of the trigeminal principal nucleus in rats.

Abstract:

:The dorsal margin of the trigeminal principal nucleus (PV) contains neurons responsive to innocuous thermal stimulation of the tongue and maybe a thermal relay (Hayama and Hashimoto, 2011). The present electrophysiological study examined whether PV thermoreceptive neurons project to the thalamus and investigated response properties to cold (20°C) or warm (40°C) stimulation of the tongue. Twenty-three thermoreceptive neurons were identified in the dorsal portion of the PV. Twenty of the 23 neurons were examined but none projected to the thalamus. Impulse frequencies of 8 of the 11 thermoreceptive neurons examined rapidly increased with cold stimulation, then decreased and gradually increased to steady state level, and rapidly decreased with warm stimulation. Thermal receptive fields were examined for six PV thermoreceptive neurons; five had a large receptive field extending over the whole anterior tongue ipsilateral to the recording side. These findings suggest that the dorsal portion of the PV is not a thermal relay mediating thermal information from the tongue to the thalamus.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Hayama T

doi

10.1016/j.neulet.2014.01.060

subject

Has Abstract

pub_date

2014-04-03 00:00:00

pages

53-6

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(14)00102-5

journal_volume

564

pub_type

杂志文章
  • Event-related potentials during exposure to aversion and its anticipation: the moderating effect of intolerance of uncertainty.

    abstract::The aim of the present study was to investigate the moderating effect of intolerance of uncertainty (IU) on exposure to aversion and its anticipation using event-related potentials (ERPs). Sixteen subjects high in IU and 16 subjects low in IU underwent an affective cueing paradigm where a warning cue signaled the vale...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.11.054

    authors: Gole M,Schäfer A,Schienle A

    更新日期:2012-01-24 00:00:00

  • Prefrontal cortex regulates burst firing and transmitter release in rat mesolimbic dopamine neurons studied in vivo.

    abstract::The influence of the medial prefrontal cortex (PFC) on mesolimbic dopamine activity was studied with electrophysiological techniques and in vivo voltammetry in the chloral hydrate-anesthetized male rat. Glutamate injected into the PFC selectively increased burst firing of single dopamine cells in the ventral tegmental...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90641-w

    authors: Murase S,Grenhoff J,Chouvet G,Gonon FG,Svensson TH

    更新日期:1993-07-09 00:00:00

  • Activation of silent synapses with sustained but not decremental long-term potentiation.

    abstract::Silent synapses display no excitatory post-synaptic currents (EPSCs) at resting potentials, but can conduct at depolarized potentials. In the hippocampal CA1 region of young animals, conversion of silent synapses to functional synapses occurs rapidly after pairing post-synaptic depolarization with 1Hz pre-synaptic sti...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2007.02.035

    authors: Kasten MR,Fan Y,Schulz PE

    更新日期:2007-04-24 00:00:00

  • Melatonin supplementation delays the decline of adult hippocampal neurogenesis during normal aging of mice.

    abstract::Melatonin modulates adult hippocampal neurogenesis in adult mice. Also, plasma melatonin levels and new neuron formation decline during aging probably causing cognitive alterations. In this study, we analyzed the impact of exogenous supplementation with melatonin in three key events of hippocampal neurogenesis during ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.09.045

    authors: Ramírez-Rodríguez G,Vega-Rivera NM,Benítez-King G,Castro-García M,Ortíz-López L

    更新日期:2012-11-14 00:00:00

  • Preservation of acetylcholine muscarinic M2 receptor G-protein interactions in the neocortex of patients with Alzheimer's disease.

    abstract::The efficacy of acetylcholine muscarinic M2 receptor-G protein coupling was investigated in Alzheimer's disease and control neocortical membranes by measuring the effects of MgCl2 and 5'-guanylylimidodiphosphate (Gpp[NH]p) on high-affinity [3H]oxotremorine-M ([3H]OXO-M) binding. MgCl2 gave similar enhancements of [3H]...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)11281-z

    authors: Hérnandez-Hérnandez A,Adem A,Ravid R,Cowburn RF

    更新日期:1995-02-15 00:00:00

  • Activation of caspase-3 pathway by expression of sGalphai2 protein in BHK cells.

    abstract::Treatment with dopamine and other dopamine D2 receptor agonists has been shown to induce cell death through activation of caspase-3 pathway. However, initial step that leads to the activation of caspase-3 in D2 receptor-mediated apoptotic pathway remains unclear. Recently, it was shown that a spliced variant of Galpha...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.04.078

    authors: López-Aranda MF,Navarro-Lobato I,López-Téllez JF,Blanco E,Masmudi-Martín M,Khan ZU

    更新日期:2008-07-04 00:00:00

  • Involvement of the septum in the regulation of paraventricular vasopressin neurons by the subfornical organ in the rat.

    abstract::Extracellular recordings were obtained from 58 phasically active neurosecretory neurons in the hypothalamic paraventricular nucleus (PVN) of urethane-anesthetized male rats. Of these PVN neurons, 39 exhibited an increase and 11 displayed a reduction in ongoing activity following electrical stimulation of the subfornic...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(88)90058-4

    authors: Tanaka J,Saito H,Seto K

    更新日期:1988-10-05 00:00:00

  • Different modifications of phosphorylated Smad3C and Smad3L through TGF-β after spinal cord injury in mice.

    abstract::Transforming growth factor-β (TGF-β) is an anti-inflammatory cytokine and is expressed in the injured spinal cord. TGF-β signals through receptors to activate Smad proteins, which translocate into the nucleus. In the present study, we investigated the chronological alterations and cellular locations of the TGF-β/Smad ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.05.042

    authors: Joko M,Osuka K,Usuda N,Atsuzawa K,Aoyama M,Takayasu M

    更新日期:2013-08-09 00:00:00

  • Cerebellar corticovestibular projections from lobule IX to the descending vestibular nucleus in the cat. A retrograde wheat germ agglutinin-horseradish peroxidase study.

    abstract::The distribution of Purkinje cells projecting to the descending vestibular nucleus was studied in lobule IX (uvula) of the cat by the retrograde wheat germ agglutinin-horseradish peroxidase method. In the transverse plane labeled Purkinje cells were seen diffusely within 1.0 mm from the midline and densely for 250-500...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90034-0

    authors: Matsushita M,Wang CL

    更新日期:1986-05-23 00:00:00

  • Leptin induces nitric oxide synthase type II in C6 glioma cells. Role for nuclear factor-kappaB in hormone effect.

    abstract::Astrocytes in the CNS produce inflammatory mediators in response to several stimuli and cytokines. Here we investigated the in vitro effect of leptin on inducible nitric oxide synthase (iNOS) expression in a glioma cell line (C6). After hormone stimulation, culture media were analysed for accumulated stable oxidation ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.11.022

    authors: Mattace Raso G,Esposito E,Iacono A,Pacilio M,Coppola A,Bianco G,Diano S,Di Carlo R,Meli R

    更新日期:2006-03-27 00:00:00

  • Retrograde effects of axotomy on the intramedullary axon collateral systems and recurrent inhibitory reflexes of cat spinal motoneurones.

    abstract::The intramedullary axon collateral systems of adult cat spinal alpha-motoneurones were studied with morphological and physiological techniques 12 weeks after peripheral transection of the motor axons. Morphologically, intracellular horseradish peroxidase (HRP) staining showed that the axotomy induced an elimination of...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(84)90343-4

    authors: Havton L,Kellerth JO

    更新日期:1984-11-23 00:00:00

  • A left-prefrontal lateralized, sympathetic mechanism directs attention towards social threat in humans: evidence from repetitive transcranial magnetic stimulation.

    abstract::The prioritized processing of threat is suggested to be motivated by anxiety, regulated by the parasympatheticus, and biased to the right hemisphere. However, according to an anterior dimensional model of negative affect this is unlikely to be true when threat is of social origin. Social threat is communicated by the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)02558-7

    authors: van Honk J,Hermans EJ,d'Alfonso AA,Schutter DJ,van Doornen L,de Haan EH

    更新日期:2002-02-15 00:00:00

  • Alterations of fatty acid composition and metabolism in APP/PS1 transgenic mice.

    abstract::Accumulating evidence suggests that abnormal fatty acid composition is related to the development of Alzheimer's disease (AD). However, there is no consistency in the fatty acid profile and metabolism associated with AD pathogenesis. This study aims to define the characteristics of fatty acid composition and metabolis...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2020.135401

    authors: Bai YR,Wang YY,Meng DL,Shi ZL,Song XF,Yang ZZ,Zhang W,Yang L,Shi RL

    更新日期:2020-11-01 00:00:00

  • Up-regulation of Hrk, a regulator of cell death, in retinal ganglion cells of axotomized rat retina.

    abstract::Hrk, a regulator of cell death, belongs to the family of pro-apoptotic BH3-only proteins and is known to induce apoptosis in nerve tissue. We examined Hrk gene expression to clarify the role of BH3-only proteins in apoptosis of retinal ganglion cells (RGCs) after optic nerve transection in the adult rat. Reverse trans...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)02487-9

    authors: Wakabayashi T,Kosaka J,Hommura S

    更新日期:2002-01-25 00:00:00

  • NOC-9, a selective nitric oxide donor, induces flight reactions in the dorsolateral periaqueductal gray of rats by activating soluble guanylate cyclase.

    abstract::Previous studies have showed that SIN-1, a nitric oxide (NO) donor, injected into the dorsolateral column of the periaqueductal gray (dlPAG) induces flight reactions. This drug, however, can also produce peroxynitrite, which may interfere in this effect. In addition, it is also unknown if this effect is mediated by lo...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.05.009

    authors: Braga AA,Aguiar DC,Guimarães FS

    更新日期:2009-08-07 00:00:00

  • Alzheimer's disease susceptibility genes modify the risk of Parkinson disease and Parkinson's disease-associated cognitive impairment.

    abstract::The pathogenic mechanism underlying Parkinson's disease (PD) and PD- Cognitive impairment (CI) remains elusive. Its potential link to the risk factors in Alzheimer's disease (AD) is unclear. In this study, we analyzed 16 CE-associated single nucleotide polymorphisms (SNPs) in twelve genes in a Chinese cohort of 450 PD...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2018.04.042

    authors: Fang L,Tang BS,Fan K,Wan CM,Yan XX,Guo JF

    更新日期:2018-06-11 00:00:00

  • The increase in morphine antinociceptive potency produced by carrageenan-induced hindpaw inflammation is blocked by naltrindole, a selective delta-opioid antagonist.

    abstract::Carrageenan-induced inflammation of the rat hindpaw has been used as a model for persistent pain of inflammatory origin. The induction of inflammation resulting from carrageenan injection in the rat hindpaw has been shown to elicit an increase in the antinociceptive potency of morphine, an effect postulated to be rela...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)11199-s

    authors: Ossipov MH,Kovelowski CJ,Porreca F

    更新日期:1995-01-30 00:00:00

  • Sex differences in prefrontal cortex microglia morphology: Impact of a two-hit model of adversity throughout development.

    abstract::Neuroimmune mechanisms play critical roles in brain development and can be impacted by early life adversity. Microglia are the resident immune cells in the brain, with both sex-specific and region-specific developmental profiles. Since early life adversity is associated with several neuropsychiatric disorders with dev...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2020.135381

    authors: Gildawie KR,Orso R,Peterzell S,Thompson V,Brenhouse HC

    更新日期:2020-11-01 00:00:00

  • Cortico-muscular coupling in a patient with postural myoclonus.

    abstract::We investigated the cortico-muscular coherence in a patient with posturally induced cortically originating negative myoclonus. We recorded simultaneously 50 channels EEG and EMG from quadriceps and biceps femoris muscles of the left upper leg. Three experimental conditions were investigated with the patient in a seate...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.05.114

    authors: Kristeva R,Popa T,Chakarov V,Hummel S

    更新日期:2004-08-19 00:00:00

  • Treadmill exercise suppresses nigrostriatal dopaminergic neuronal loss in 6-hydroxydopamine-induced Parkinson's rats.

    abstract::In Parkinson's disease, the progressive loss of dopaminergic neurons in the pars compacta of the substantia nigra leads to debilitating motor dysfunction. In the present study, we investigated the effects of treadmill exercise on the dopaminergic neuronal cell death in the substantia nigra and on the dopaminergic fibe...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2007.06.031

    authors: Yoon MC,Shin MS,Kim TS,Kim BK,Ko IG,Sung YH,Kim SE,Lee HH,Kim YP,Kim CJ

    更新日期:2007-08-09 00:00:00

  • Effect of the histone deacetylase inhibitors on behavioural sensitization to a single morphine exposure in mice.

    abstract::Behavioural sensitization to a single morphine exposure has been considered to be a long-term form of behavioural plasticity associated with opioid addiction. Accumulated evidence has shown that histone modification plays a key role in behavioural plasticity. Therefore, this study was designed to investigate whether t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.03.005

    authors: Jing L,Luo J,Zhang M,Qin WJ,Li YL,Liu Q,Wang YT,Lawrence AJ,Liang JH

    更新日期:2011-04-25 00:00:00

  • Ablation of nucleus isthmi leads to loss of specific visually elicited behaviors in the frog Rana pipiens.

    abstract::Ablation of the frog's nucleus isthmi results in a visual scotoma contralateral to the lesion. Within the scotoma, animals do not respond to visually presented prey or threats. The locus of visual loss is related to the area of isthmal tissue ablated. With complete unilateral ablation, a frog displays no visually elic...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(85)80096-3

    authors: Caine HS,Gruberg ER

    更新日期:1985-03-15 00:00:00

  • The inactivation of extracellular signal-regulated kinase by glucagon-like peptide-1 contributes to neuroprotection against oxidative stress.

    abstract::Glucagon-like peptide-1 (GLP-1), an insulinotropic peptide secreted from enteroendocrine cells, has been known to have a neuroprotective effect. However, it is not fully understood the intracellular mediator of GLP-1 signaling in neuronal cells. In the present study, we examined the change in intracellular signaling o...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.01.052

    authors: Nakajima S,Numakawa T,Adachi N,Yoon HS,Odaka H,Ooshima Y,Kunugi H

    更新日期:2016-03-11 00:00:00

  • Calyculin A blocks bovine chromaffin cell calcium channels independently of phosphatase inhibition.

    abstract::The specific phosphatase inhibitor, Calyculin-A (CL-A), decreases high-K stimulated catecholamine secretion in bovine chromaffin cells. This effect can be split into two components: one needs long exposures to the drug to be elicited, and is sensitive to the protein kinase-inhibitor K252a; the other is observed after ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90288-7

    authors: Gutiérrez LM,Viniegra S,Quintanar JL,Reig JA,Sala F

    更新日期:1994-08-29 00:00:00

  • Effects of extracts of denervated muscles on the morphology of cultured muscle cells.

    abstract::Previously, trophic effects of extracts from whole chick embryos and from innervated muscles on cultured muscle cells were described. The present study demonstrated similar effects of extracts from 10-days denervated chick muscles. Extracts from innervated as well as from denervated muscles exsanguinated in vivo with ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(81)90283-4

    authors: Hooisma J,De Krijger J,De Groot DM,Magchielse T,Muijser H

    更新日期:1981-02-23 00:00:00

  • Effects on reflex bladder activity of chemical stimulation of small diameter afferents from skeletal muscle in the cat.

    abstract::In anesthetized cats selective activation of fine muscle afferents of the hindlimb by KCl or bradykinin (Brad.) induced reflex changes in the urinary bladder. The nature of the reflex responses depended on the functional state of the bladder: they were excitatory when the bladder was quiescent and inhibitory during la...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(79)90048-x

    authors: Sato A,Sato Y,Schmidt PF

    更新日期:1979-01-01 00:00:00

  • APOE promoter polymorphisms and dementia in the elderly.

    abstract::Previous observations suggest a contribution of two APOE promoter polymorphisms (-219 G/T and -491 A/T) in dementia. From two independent populations of elderly (mean age of 84 and 85 years old, respectively), we observed that subjects bearing the -219T allele were at increased risk of dementia (OR = 1.9 (95% CI, 1.3-...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.04.063

    authors: Lambert JC,Berr C,Cottel D,Amouyel P,Helbecque N

    更新日期:2004-07-22 00:00:00

  • α-Iso-cubebene exerts neuroprotective effects in amyloid beta stimulated microglia activation.

    abstract::Schisandra chinensis is commonly used for food and as a traditional remedy for the treatment of neuronal disorders. However, it is unclear which component of S. chinensis is responsible for its neuropharmacological effects. To answer this question, we isolated α-iso-cubebene, a dibenzocyclooctadiene lignin, from S. ch...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.09.053

    authors: Park SY,Park SJ,Park NJ,Joo WH,Lee SJ,Choi YW

    更新日期:2013-10-25 00:00:00

  • An increase in striatal Met-enkephalin-like immunoreactivity in neonatally dopamine-depleted rats.

    abstract::A pronounced decrease in dopamine content in both the striatum and the mesolimbic area was observed up to 120 days of age after treatment with 6-hydroxydopamine (100 micrograms, intracisternally) following desipramine pretreatment (20 mg/kg, i.p.) at the 5th postnatal day. In the 6-hydroxydopamine-treated rats, Met-en...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(88)90154-1

    authors: Kurumaji A,Takashima M,Watanabe S,Takahashi K

    更新日期:1988-04-22 00:00:00

  • Reciprocal changes in the expression of neurotrophin mRNAs in target tissues and peripheral nerves of aged rats.

    abstract::trk receptors are downregulated in both dorsal root ganglion (DRG) and spinal motoneurons of aged rats with behavioral sensorimotor deficits. Here we provide evidence, using reverse transcription-polymerase chain reaction (RT-PCR), of decreased levels of neurotrophin (nerve growth factor, NGF; brain-derived neurotroph...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00655-2

    authors: Ming Y,Bergman E,Edström E,Ulfhake B

    更新日期:1999-10-08 00:00:00