Retrograde effects of axotomy on the intramedullary axon collateral systems and recurrent inhibitory reflexes of cat spinal motoneurones.

Abstract:

:The intramedullary axon collateral systems of adult cat spinal alpha-motoneurones were studied with morphological and physiological techniques 12 weeks after peripheral transection of the motor axons. Morphologically, intracellular horseradish peroxidase (HRP) staining showed that the axotomy induced an elimination of whole collateral trees from the proximal parts of the lesioned axons. The axon collateral systems that still remained in the axotomized neurones appeared quite normal. Physiologically, intracellular recordings failed to reveal a corresponding reduction in the amount of recurrent inhibition produced by the axotomized cells. Possible explanations for the discrepancy between the morphological and physiological results are discussed.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Havton L,Kellerth JO

doi

10.1016/0304-3940(84)90343-4

subject

Has Abstract

pub_date

1984-11-23 00:00:00

pages

13-7

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(84)90343-4

journal_volume

52

pub_type

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