Abstract：
:Rats subjected to forced oral self-administration of morphine solutions without or in combination with two daily i.p. injections of morphine preferred drinking water when this was offered in addition to morphine solutions. The daily intake of morphine during the terminal phase of self-administration of morphine was 50-80 mg/kg (oral application alone) or 270 mg/kg (oral and i.p. application). Morphine treated animals showed withdrawal symptoms on administration of naloxone 1 mg/kg i.p. during the period of self-administration, but not when they had started drinking exclusively water. The tail-flick test revealed no tolerance during prolonged treatment with morphine. The results indicate that no psychological dependence developed when morphine was applied orally and regularly.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Jurna I,Baldauf J,Zenz Mdoi
10.1016/0304-3940(92)90476-nkeywords:
subject
Has Abstractpub_date
1992-04-13 00:00:00pages
77-80issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(92)90476-Njournal_volume
138pub_type
杂志文章abstract：:In all mammals so far investigated the occurrence of ponto-geniculo-occipital (PGO) waves precedes the onset and maintenance of desynchronized (D) sleep. As unitary electrographic events, PGO waves provide an index for quantitative evaluation of physiological D sleep or the D sleep-like state evoked by centrally admin...
journal_title：Neuroscience letters
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doi：10.1016/0304-3940(87)90269-2
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abstract：:The taiep rat is a myelin mutant whose immobility episodes (IEs) can be caused by gripping them by the tail. Electroencephalographic recordings during IEs show a rapid-eye movement sleep-like pattern, similar to narcolepsy-cataplexy in canines. Systemic administration of alpha(2)-adrenoceptor agonists and the alpha(1)...
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2014.04.041
更新日期：2014-06-24 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：1999-11-26 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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更新日期：2004-04-08 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：1984-09-07 00:00:00
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journal_title：Neuroscience letters
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更新日期：1999-09-10 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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更新日期：1999-05-21 00:00:00
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更新日期：2005-05-13 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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更新日期：2011-04-08 00:00:00
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journal_title：Neuroscience letters
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更新日期：2005-03-03 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：2016-05-16 00:00:00
abstract：:When a tone-burst train with a short inter-burst interval is lateralized to the left and is followed by another tone-burst train lateralized to the right, listeners report a smooth shift of tone bursts along the intracranial axis from left to right (known as auditory saltation). When a sequence of tone bursts with a c...
journal_title：Neuroscience letters
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更新日期：2010-01-14 00:00:00
