Abstract:
:Oligodendrocytes in different central nervous system regions have dissimilar morphologies. In order to find out if immature oligodendrocytes develop different phenotypes spontaneously, neonatal spinal and cerebral rat oligodendrocytes were cultured in vitro in the absence of neurons. The results show that spinal oligodendrocytes tend to develop a bipolar structure with few processes, while cerebral cells tend to become multipolar with many processes. A similar spinal-cerebral difference was seen in oligodendrocyte-enriched cultures. Hence, spinal and cerebral oligodendrocytes develop partly different morphologies in vitro.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Bjartmar Cdoi
10.1016/s0304-3940(98)00264-xsubject
Has Abstractpub_date
1998-05-15 00:00:00pages
91-4issue
2-3eissn
0304-3940issn
1872-7972pii
S0304-3940(98)00264-Xjournal_volume
247pub_type
杂志文章abstract::In order to test the hypothesis that ethanol (EtOH)-induced changes in growth factor signal transduction contribute to the teratogenic effects of EtOH in the developing brain, neonatal rat pups were administered a single dose of EtOH during the brain growth spurt (5 days of age, PN5). Hippocampal mitogen-activated/ext...
journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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