The somatostatin receptor (sst1) modulates the release of somatostatin in rat retina.

abstract：:The present study was designed to test the hypothesis that alpha-tocopherol (Vit. E) and pyrrolidine dithiocarbamate (PDTC) might exert direct effects on alcohol-induced contractions of canine basilar cerebral arteries. After precontraction of arterial ring segments with ethanol, PDTC (10(-8)-10(-6) M) and Vit. E (10(...

journal_title：Neuroscience letters

authors： Li W,Zheng T,Altura BT,Altura BM

更新日期：2001-03-30 00:00:00

abstract：:The present study was undertaken to investigate whether benzodiazepine receptors are involved in either the anticonvulsant activity of phenytoin against supramaximal seizures or maximal threshold seizures induced by electroshock or the neurotoxicity of phenytoin. Ro 15-1788, a benzodiazepine receptor antagonist, rever...

journal_title：Neuroscience letters

authors： Chweh AY,Swinyard EA,Wolf HH

更新日期：1985-06-24 00:00:00

abstract：:Interactions between emotional stress due to fear and hypovolemic stimuli on vasopressin secretion were studied in rats. Intraperitoneally injected dextran did not significantly change plasma osmolality and arterial blood pressure but increased blood hemoglobin and plasma vasopressin level. An i.v. infused physiologic...

journal_title：Neuroscience letters

authors： Onaka T,Yagi K

更新日期：1990-12-11 00:00:00

abstract：:Somatostatin (SRIF) release from rat hypothalamus was investigated in vitro with a perifusion system. Glucagon (1 microM) and high potassium concentrations (56 mM) stimulated SRIF release in a calcium-dependent manner. Pretreatment of the rat with cysteamine (30 mg/100 g body weight, 7 h earlier) significantly reduced...

journal_title：Neuroscience letters

authors： Shimatsu A,Kato Y,Matsushita N,Ohta H,Kabayama Y,Imura H

更新日期：1983-06-30 00:00:00

abstract：:Thioredoxin (TRX) is a small, multifunctional protein with a redox-active site and multiple biological functions that include reducing activity for reactive oxygen intermediates. We assayed TRX by immunohistochemical methods in the rat brain after intraperitoneal injection of 3-nitropropionic acid (3-NP), an irreversi...

journal_title：Neuroscience letters

authors： Sugino T,Nozaki K,Takagi Y,Hattori I,Hashimoto N,Yodoi J

更新日期：1999-11-12 00:00:00

abstract：:Carrier-mediated transport of small peptides and peptidomimetics offers the opportunity for a targeted drug delivery across cell membranes in the central nervous system (CNS). This process is mediated by the proton-coupled transporter PEPT2 which is expressed in glial and choroid plexus cells. In the present studies, ...

journal_title：Neuroscience letters

authors： Groneberg DA,Rubio-Aliaga I,Nickolaus M,Döring F,Fischer A,Daniel H

更新日期：2004-06-24 00:00:00

abstract：:L-Histidine decarboxylase catalyzes the formation of histamine from the amino acid L-histidine. We have studied the distribution of neurons expressing mRNA for histidine decarboxylase in adult rat brain using in situ hybridization with synthetic oligonucleotide probes. The expression of mRNA for histidine decarboxylas...

journal_title：Neuroscience letters

authors： Castrén E,Panula P

更新日期：1990-11-27 00:00:00

abstract：:Expression of vasoactive intestinal polypeptide (VIP) was studied in regenerating adult rat dorsal root ganglion (DRG) neurons in culture. VIP was not detected by radioimmunoassay in newly established cultures but increasing concentrations were observed between 2 and 4 days and VIP remained detectable for more than 2 ...

journal_title：Neuroscience letters

authors： Mulderry PK,Lindsay RM

更新日期：1990-01-22 00:00:00

abstract：:A two-tone oddball procedure was employed to examine the effect of a phonemic category on the mismatch negativity (MMN). One of the stimuli was a phoneme prototype of Japanese /e/, and the other, [e/ö], which was perceived by Japanese participants as showing deviance from typicality but is nonetheless included in the ...

journal_title：Neuroscience letters

authors： Ikeda K,Hayashi A,Hashimoto S,Otomo K,Kanno A

更新日期：2002-03-22 00:00:00

abstract：:Incorporation of ubiquitin and ubiquitin-related proteins including p62 into neuronal intranuclear inclusions (NIIs) has been reported in a variety of neurodegenerative diseases. However, involvement of autophagy-specific proteins (NBR1 and LC3) in NIIs has not been mentioned. We immunohistochemically examined the bra...

journal_title：Neuroscience letters

authors： Mori F,Tanji K,Odagiri S,Toyoshima Y,Yoshida M,Kakita A,Takahashi H,Wakabayashi K

更新日期：2012-08-01 00:00:00

abstract：:Previous studies have demonstrated that both visual and proprioceptive feedback influence motor control. The relative contributions of these sensory modalities to the on-line computation of body position--that is, the body schema--remain unclear. We report a study designed to explore the roles of vision and propriocep...

journal_title：Neuroscience letters

authors： Shenton JT,Schwoebel J,Coslett HB

更新日期：2004-11-03 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurodegenerative disease. Majority of PD cases are sporadic, resulting from interaction of genetic and environmental factors. Accumulating evidence indicates that autophagy, which delivers alpha-synuclein to lysosomes for degradation, is involved in the PD pathogenesis. Some ...

journal_title：Neuroscience letters

authors： Wu G,Pang S,Feng X,Zhang A,Li J,Gu K,Huang J,Dong H,Yan B

更新日期：2011-08-01 00:00:00

abstract：:In this study we measured activation patterns in the primary visual cortex and the frontal language areas and compared them in individuals with strong and weak capacities to mentally visualize information during spontaneous thinking. Subjects were first administered a 5-item questionnaire to assess their ability to cr...

journal_title：Neuroscience letters

authors： Nishimura K,Aoki T,Inagawa M,Tobinaga Y,Iwaki S

更新日期：2015-05-06 00:00:00

abstract：:The IKK/NF-κB signalling pathway plays a predominant role in the regulation of inflammation and apoptosis in spinal cord injury (SCI). We have previously demonstrated that targeting of the IKK/NF-κB pathway improved the recovery of locomotor function by reducing the infiltration of inflammatory cells and apoptosis aft...

journal_title：Neuroscience letters

authors： Lu M,Wang S,Han X,Lv D

更新日期：2013-05-10 00:00:00

abstract：:Prolonged exposure of hippocampal slices to L-glutamate was found to produce a biphasic effect on excitatory synaptic transmission from Schaffer collateral-commissural fibers to CA1 pyramidal neurons: an early blockade of postsynaptic responses was followed by a progressive recovery. Antagonists of N-methyl-D-aspartat...

journal_title：Neuroscience letters

authors： Krishtal OA,Smirnov SV,Osipchuk YuV

更新日期：1988-02-15 00:00:00

abstract：:Single photon-induced transient currents, called quantum bumps were stimulated by short flashes in dark-adapted ventral nerve photoreceptors of Limulus. Flash intensities were set to activate 3 or more bumps. In most cases, current bumps were activated with a constant rate. The frequency of bump occurrence was between...

journal_title：Neuroscience letters

authors： Nagy K

更新日期：1992-09-14 00:00:00

abstract：:The pharmacology of the metabotropic glutamate receptor (mGluR)-mediated potentiation of N-methyl-D-aspartate (NMDA)-evoked depolarisations in the CA1 region of rat hippocampal slices was investigated using an extracellular grease-gap method. The group I and II mGluR agonist (1S,3R)-1-aminocyclopentane-1,3-dicarboxyli...

journal_title：Neuroscience letters

authors： Fitzjohn SM,Irving AJ,Palmer MJ,Harvey J,Lodge D,Collingridge GL

更新日期：1996-01-26 00:00:00

abstract：:DJ-1, the causative gene of a familial form of Parkinson's disease (PD), has been reported undergo oxidation preferentially at the 106th cysteine residue (Cys-106) under oxidative stress. Recently, it has been found that the levels of oxidized DJ-1 in erythrocytes of unmedicated PD patients are markedly higher than th...

journal_title：Neuroscience letters

authors： Akazawa YO,Saito Y,Hamakubo T,Masuo Y,Yoshida Y,Nishio K,Shichiri M,Miyasaka T,Iwanari H,Mochizuki Y,Kodama T,Noguchi N,Niki E

更新日期：2010-10-15 00:00:00

abstract：:The possible involvement of 2-amino-4-phosphonobutyrate (APB) recognition sites in mechanisms enabling the maintenance of long-term potentiation (LTP) was investigated in rat hippocampal slices. The action of D(-)- and L(+)-isomers of APB was tested on orthodromic EPSP and spike responses recorded extracellularly from...

journal_title：Neuroscience letters

authors： Reymann KG,Matthies H

更新日期：1989-03-27 00:00:00

abstract：:A possible role of the human cerebellum in the generation of verbs corresponding to presented nouns has been suggested. Previous functional brain imaging studies have compared generation of verbs with the reading of nouns as a measure of verb generation. In the present fMRI study involving healthy human subjects, the ...

journal_title：Neuroscience letters

authors： Frings M,Dimitrova A,Schorn CF,Elles HG,Hein-Kropp C,Gizewski ER,Diener HC,Timmann D

更新日期：2006-11-27 00:00:00

abstract：:It has been proposed that the perception of a coherent image necessitates two processes, that is, an ensemble of neurons which synchronizes discharges of individual cells and stimulus-specific gamma-band (gamma) neuronal oscillations which may serve as carrier signals for a temporal code. We tested the hypothesis that...

journal_title：Neuroscience letters

authors： Shumikhina S,Molotchnikoff S

更新日期：1999-09-10 00:00:00

abstract：:We examined the caudate spindle in control and pargyline-pretreated rats following bilateral application of 3 doses (15, 50 and 150 micrograms/site) of dopamine (DA) into the caudate nucleus. The highest dose of DA (150 micrograms) suppressed the spindle, whereas lower doses (15, 50 micrograms) enhanced the spindle in...

journal_title：Neuroscience letters

authors： Okuyama S,Hashimoto S,Aihara H

更新日期：1985-08-16 00:00:00

abstract：:Ischemic cerebrovascular diseases, usually involved in hypoxia and reoxygenation, have been reported to increase the risk of dementia such as Alzheimer's disease (AD). beta-site amyloid protein precursor (APP)-cleaving enzymes (BACE1) have been identified to participate in the secretion of beta-amyloid peptides (Abeta...

journal_title：Neuroscience letters

authors： Xue S,Jia L,Jia J

更新日期：2006-09-25 00:00:00

abstract：:We determined the effect of naloxone and morphine on the differentiation of pheochromocytoma cell, the PC12 cells, induced by nerve growth factor (NGF). PC12 cells were grown in medium containing NGF with or without the addition of naloxone or morphine for up to 10-day treatments. NGF-induced morphological differentia...

journal_title：Neuroscience letters

authors： Yeh GC,Hsieh TH,Chang SF

更新日期：1998-08-07 00:00:00

abstract：:Axons in chronically demyelinated spinal cord lesions, induced by ethidium bromide injection, display patches of intramembranous particles and indentations resembling nodal and paranodal axolemmal specializations respectively. Both occur in the marginal region of the lesions where the demyelinated axons are intimately...

journal_title：Neuroscience letters

authors： Rosenbluth J,Blakemore WF

更新日期：1984-07-27 00:00:00

abstract：:The study investigated the effects of metabolic syndrome on urinary bladder nerve-growth factor (NGF) and p75(NTR) expression in fructose-fed obese rats. Age-matched male Wistar rats were divided into four groups; group I: normal control rats; group II: 6-week fructose-fed rats (FR); group III: 9-week FR; and group IV...

journal_title：Neuroscience letters

authors： Cheng JT,Tong YC

更新日期：2008-08-15 00:00:00

abstract：:It has been indicated that Src family protein tyrosine kinases (SrcPTKs) potentiate N-methyl-D-aspartate (NMDA) receptor function by phosphorylating NR2A subunits and that postsynaptic density protein 95 (PSD-95) facilitates this regulation. In this paper, we define the role of SrcPTKs in delayed neuronal damage follo...

journal_title：Neuroscience letters

authors： Hou XY,Liu Y,Zhang GY

更新日期：2007-06-15 00:00:00

abstract：:1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) kills tumor cells via multiple actions including alkylation and carbamoylation. Previously, we have reported that formation of S-nitrosoglutathione (GSNO) in glioma cells overexpressing inducible nitric oxide synthase (iNOS) contributed to nitric oxide (NO)-dependent carbamo...

journal_title：Neuroscience letters

authors： Yang JJ,Yin JH,Yang DI

更新日期：2007-05-11 00:00:00

abstract：:Increasing evidence shows that inflammation may contribute to the pathophysiology of depression. Apigenin, one type of natural flavone, has a number of biological actions including anti-inflammatory effects. Although it has potential antidepressant activity in a chronic mild stress model, the mechanisms of antidepress...

journal_title：Neuroscience letters

authors： Li R,Zhao D,Qu R,Fu Q,Ma S

更新日期：2015-05-06 00:00:00

abstract：:To assess the neurotrophic effects of a nootropic drug, aniracetam, we studied neurite extension of mouse cerebellar granule cells in culture with low or with high K+ under different combinations of drugs and then immunohistochemically stained the cells with an antibody against L1, a neural cell adhesion molecule on c...

journal_title：Neuroscience letters

authors： Fushiki S,Matsumoto K,Nagata A

更新日期：1995-10-27 00:00:00