Abstract:
:Axons in chronically demyelinated spinal cord lesions, induced by ethidium bromide injection, display patches of intramembranous particles and indentations resembling nodal and paranodal axolemmal specializations respectively. Both occur in the marginal region of the lesions where the demyelinated axons are intimately associated with astrocytic and oligodendrocytic processes, and probably correspond to the aberrant node-like and paranodal junctional complexes seen in thin sections of this region. Demyelinated axons in the center of the lesion, which are not in contact with glial processes, do not display these membrane specializations.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Rosenbluth J,Blakemore WFdoi
10.1016/0304-3940(84)90015-6subject
Has Abstractpub_date
1984-07-27 00:00:00pages
171-7issue
2eissn
0304-3940issn
1872-7972pii
0304-3940(84)90015-6journal_volume
48pub_type
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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