Abstract:
:The human basal forebrain has been known to contain many neurons immunoreactive (ir) to tyrosine hydroxylase (TH; the first dopamine-synthesizing enzyme). We examined whether these neurons might contain aromatic L-amino acid decarboxylase (AADC; the second step dopamine-synthesizing enzyme) by dual labeling immunohistochemistry and confocal laser-scanning microscopy. Neurons dually-labeled for TH and AADC were found in the anterior olfactory nucleus, olfactory tubercle and the ventral margin of the rostral nucleus accumbens. The examination in the basal forebrain of the macaque monkey also gave substantially the same results. These neurons appear to constitute an independent dopaminergic cell group in the primate basal forebrain.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Ikemoto K,Nagatsu I,Kitahama K,Jouvet A,Nishimura A,Nishi K,Maeda T,Arai Rdoi
10.1016/s0304-3940(98)00103-7subject
Has Abstractpub_date
1998-02-27 00:00:00pages
129-32issue
1-3eissn
0304-3940issn
1872-7972pii
S0304-3940(98)00103-7journal_volume
243pub_type
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