Dopamine and noradrenaline release in the prefrontal cortex of rats during classical aversive and appetitive conditioning to a contextual stimulus: interference by novelty effects.

abstract：:Aggression reflects the psychological and physical behavior that perpetrator intends to harm victim. Initiation of aggression is influenced by the distal factors (e.g. personality) and proximate causes (e.g. affect) of perpetrator. However, few studies explored the brain structural basis of relationship between these ...

journal_title：Neuroscience letters

authors： Zhu X,Wang K,Cao A,Zhang Y,Qiu J

更新日期：2020-01-23 00:00:00

abstract：:Topographical maps form the basis of the organization in many projections within the central nervous system, but in the neuromuscular system such detailed spatial organization has generally been assumed to be absent and indeed unnecessary for normal function (see, for example, ref. 1). However, there is some physiolog...

journal_title：Neuroscience letters

authors： Hardman VJ,Brown MC

更新日期：1985-10-10 00:00:00

abstract：:Antidepressants such as tricyclic antidepressants, and serotonin noradrenaline reuptake inhibitors are a first-line treatment for neuropathic pain. Here, we aimed to determine the involvement of the spinal dopaminergic system in the antihyperalgesic effects of antidepressants in a rat model of neuropathic pain induced...

journal_title：Neuroscience letters

authors： Chen M,Hoshino H,Saito S,Yang Y,Obata H

更新日期：2017-05-10 00:00:00

abstract：:Pain is the most characteristic feature of sickle cell disease (SCD). Patients with SCD live with unpredictable, recurrent episodes of acute painful crisis, as well as chronic unremitting pain throughout their lifetime. While most of the research and medical efforts have focused on treating vaso-occlusion crisis and a...

journal_title：Neuroscience letters

authors： He Y,Wang ZJ

更新日期：2019-07-27 00:00:00

abstract：:Tenascin-R (TN-R) is a neural specific protein and an important molecule involved in inhibition of axonal regeneration after spinal cord injury (SCI). Here we report on rabbit-derived TN-R polyclonal antibody, which acts as a TN-R antagonist with high titer and high specificity, promoted neurite outgrowth and sproutin...

journal_title：Neuroscience letters

authors： You J,Hong SQ,Zhang MY,Zhao HL,Liu TZ,Zhou HL,Cai YQ,Xu ZM,Guo Y,Jiang XD,Xu RX

更新日期：2012-09-13 00:00:00

abstract：:The effect of aconitine, a plant alkaloid known to bind at site 2 of the sodium channel, was investigated on neuronal excitability in hippocampal slices of adult and juvenile rats. Aconitine (0.01-1 microM) diminished the extracellularly recorded population spike in a concentration-dependent manner. At each concentrat...

journal_title：Neuroscience letters

authors： Ameri A

更新日期：1996-09-20 00:00:00

abstract：:Direct administration of interleukin-1beta (IL-1beta) into the lateral cerebral ventricle of rat brain, in addition to inducing febrile responses, upregulated the immunoreactivity of tryptophan hydroxylase in the preoptic anterior hypothalamus. The fever induced by IL-1beta was significantly attenuated by pretreatment...

journal_title：Neuroscience letters

authors： Chio CC,Tsai SM,Wang JJ,Lin MT

更新日期：2005-06-10 00:00:00

abstract：:Recent evidence has suggested that down-regulation of somatostatin (SST) expression in the human brain during early stages of aging leads to an elevation in the steady-state levels of Abeta and therefore may be involved in Alzheimer's disease (AD) progression. We hypothesized that alterations in the SST gene might alt...

journal_title：Neuroscience letters

authors： Xue S,Jia L,Jia J

更新日期：2009-11-13 00:00:00

abstract：:The interaction of NMDA receptor (NMDAR) activation and other mechanisms regulating neuronal excitability have not been thoroughly described. While excess activation of NMDARs results in excitotoxicity, partial activation of NMDARs by d-cycloserine (DCS) is nootropic, enhancing both acquisition and extinction of memor...

journal_title：Neuroscience letters

authors： Donzis EJ,Thompson LT

更新日期：2014-06-13 00:00:00

abstract：:It has recently been shown that noise can improve the detection of stimuli in several sensory modalities. We herein investigated whether visual contrast detection sensitivity can be improved by adding a certain amount of noise. The contrast detection thresholds of a light changing brightness periodically were measured...

journal_title：Neuroscience letters

authors： Sasaki H,Todorokihara M,Ishida T,Miyachi J,Kitamura T,Aoki R

更新日期：2006-11-13 00:00:00

abstract：:Aquaporin-1 (AQP1) is a water channel expressed in the choroid plexus and participates in forming cerebrospinal fluid. Interestingly, reactive astrocytes also express AQP1 in the central nervous system under some pathological conditions. On the other hand, 3-nitropropionic acid (3NP) is a mitochondrial toxin that caus...

journal_title：Neuroscience letters

authors： Hoshi A,Tsunoda A,Yamamoto T,Tada M,Kakita A,Ugawa Y

更新日期：2016-07-28 00:00:00

abstract：:Glutamate receptor interacting protein (GRIP) is a member of the PDZ domain-containing protein family that is localized in the postsynaptic density area. This protein has been reported to interact specifically with the C-termini of AMPA-selective glutamate receptor channel subunits, GluRalpha2 and GluRalpha3 through i...

journal_title：Neuroscience letters

authors： Yamazaki M,Fukaya M,Abe M,Ikeno K,Kakizaki T,Watanabe M,Sakimura K

更新日期：2001-05-18 00:00:00

abstract：:Activation of several immediate early genes (IEGs) is crucial for long-term memory formation in vivo. In vitro methods of inducing these genes have not been investigated extensively. Here we present data demonstrating that application of the neurotrophin, nerve growth factor (NGF), to both rat primary neuronal culture...

journal_title：Neuroscience letters

authors： Dickey CA,De Mesquita DD,Morgan D,Pennypacker KR

更新日期：2004-08-05 00:00:00

abstract：:In this report, we describe an efficient and non-enzymatic method for isolating and culturing endothelial cells (ECs) from the nidus of surgically resected arteriovenous malformation (AVM) specimens. These cultured cells possessed typical phenotypic markers (i.e. von Willebrand factor and CD34), as well as morphologic...

journal_title：Neuroscience letters

authors： Zhang HF,Liang GB,Zhao MG,Song ZQ,Xu ZH

更新日期：2013-08-26 00:00:00

abstract：:A dimeric form of acetylcholinesterase from the electric organ of Torpedo californica was solubilized by phosphatidylinositol-specific phospholipase C from Staphylococcus aureus. The solubilized enzyme had a sedimentation coefficient of 7.3S which was not modified by detergents. The high salt-soluble asymmetric forms ...

journal_title：Neuroscience letters

authors： Futerman AH,Low MG,Silman I

更新日期：1983-09-19 00:00:00

abstract：:Nicotine and smoking have long been proved to play an important role in cognition and memory in the hippocampus. This effect is closely related to the gamma-aminobutyric acid (GABA)ergic system. Previous research has focused on functional and pharmacological aspects of nicotine's modulation activity. In this study, th...

journal_title：Neuroscience letters

authors： Li SP,Park MS,Bahk JY,Kim MO

更新日期：2002-12-13 00:00:00

abstract：:A late hyperpolarization (LH) which follows low level to moderate synaptic stimulation of neurons in the hippocampal formation neurons was previously shown to consist primarily of a potassium conductance. The present experiments showed that when extracellular cesium was present in order to reduce anamolous rectificati...

journal_title：Neuroscience letters

authors： Thalmann RH

更新日期：1984-04-20 00:00:00

abstract：:A great amount of evidence suggests that neuroinflammation may be a major pathogenetic mechanism in the pathophysiology of sporadic Alzheimer's Disease (sAD). Recently, polymorphisms in the endothelial nitric oxide synthase (NOS3) gene have been associated to late onset Alzheimer's Disease in a British population. How...

journal_title：Neuroscience letters

authors： Monastero R,Cefalù AB,Camarda C,Buglino CM,Mannino M,Barbagallo CM,Lopez G,Camarda LK,Travali S,Camarda R,Averna MR

更新日期：2003-05-08 00:00:00

abstract：:GABA transaminase activity is reduced in autopsied putamen samples from patients dying with Huntington's disease. Its activity is also reduced in the striatum of rats previously lesioned with kainic acid. In both cases, the reduction in GABA transaminase activity is comparable with the reduction in glutamate decarboxy...

journal_title：Neuroscience letters

authors： Carter CJ

更新日期：1984-08-10 00:00:00

abstract：:Current diagnosis of Major depressive disorder (MDD) depends on its clinical symptoms, not on the results of any laboratory examinations. Establishing biological markers for diagnosis of MDD is one of the most important problems to be solved in psychiatry practice. MDD patients (n=8) and a healthy control group (n=8) ...

journal_title：Neuroscience letters

authors： Wei K,Xue HL,Guan YH,Zuo CT,Ge JJ,Zhang HY,Liu BJ,Cao YX,Dong JC,Du YJ

更新日期：2016-08-26 00:00:00

abstract：:We studied event-related desynchronization (ERD) of the 8-13 Hz rhythm (mu rhythm) of the primary somatosensory cortex (SI) caused by contra- and ipsilateral median-nerve stimulation. We used whole-head magnetoencephalography (MEG) and wavelet analysis together with our newly developed color-coded single-trial ERD dis...

journal_title：Neuroscience letters

authors： Nikouline VV,Linkenkaer-Hansen K,Wikström H,Kesäniemi M,Antonova EV,Ilmoniemi RJ,Huttunen J

更新日期：2000-11-24 00:00:00

abstract：:This study assessed the effect of the kappa opioid receptor agonist U50,488 administered into the rat temporomandibular joint (TMJ) on nociceptive behavioral responses evoked by formalin injected into the same site. Groups consisted of females, stratified into proestrus and diestrus phases of the estrous cycle, and ma...

journal_title：Neuroscience letters

authors： Clemente JT,Parada CA,Veiga MC,Gear RW,Tambeli CH

更新日期：2004-12-06 00:00:00

abstract：:Representation of peripheral branches of the facial nerve within the facial nucleus of the cat was examined by utilizing retrograde axonal transport of horseradish peroxidase (HRP), which was injected into groups of muscles supplied by each of the main peripheral branches of the facial nerve. The cervical branch was r...

journal_title：Neuroscience letters

authors： Kume M,Uemura M,Matsuda K,Matsushima R,Mizuno N

更新日期：1978-04-01 00:00:00

abstract：:kappa-Opioid receptors were radiolabelled with the peptides [125I]dynorphin(1-8) and [3H]dynorphin(1-8) or with [3H]etorphine on guinea pig forebrain and cerebellar sections and visualized by quantitative autoradiography. All three radioligands yielded similar patterns of kappa-receptor localization. However, quantita...

journal_title：Neuroscience letters

authors： Sharif NA,Hunter JC,Hill RG,Hughes J

更新日期：1988-04-12 00:00:00

abstract：:While alpha- and beta-synuclein largely overlap in their expression in the vertebrate brain, only alpha-synuclein accumulates in the fibrillar aggregates typical of Parkinson's disease. It is thus critical to have immunological reagents that distinguish between these two protein isoforms. The monoclonal antibody Syn-1...

journal_title：Neuroscience letters

authors： Perrin RJ,Payton JE,Barnett DH,Wraight CL,Woods WS,Ye L,George JM

更新日期：2003-10-02 00:00:00

abstract：:Emotional processing in coma remains an open question. Skin conductance responses to emotional and neutral auditory stimuli were recorded in 13 low-responsive patients (12 of whom were in coma). A differential response between emotional and neutral stimuli was found, which significantly correlated with the Glasgow Com...

journal_title：Neuroscience letters

authors： Daltrozzo J,Wioland N,Mutschler V,Lutun P,Calon B,Meyer A,Jaeger A,Pottecher T,Kotchoubey B

更新日期：2010-05-07 00:00:00

abstract：:Global cerebral ischemia-reperfusion (GCI/R) may occur after any of several clinical conditions such as cardiac arrest and anesthetic accident. Some dopamine receptor agonists possess neuroprotective effects. However, some of them may produce side effects during treatment. Piribedil, which is a dopamine D2/D3 receptor...

journal_title：Neuroscience letters

authors： Wang W,Liu L,Chen C,Jiang P,Zhang T

更新日期：2018-09-25 00:00:00

abstract：:After systemic administration of the dopamine agonist apomorphine (APO) in common toads Bufo bufo spinosus, the excitatory receptive fields of retinal R2 and R3 ganglion cells doubled their size and the response activities of these neurons to moving visual stimuli were generally increased. Comparable investigations of...

journal_title：Neuroscience letters

authors： Glagow M,Ewert JP

更新日期：1994-05-23 00:00:00

abstract：:Low doses of colchicine (greater than 0.5 microgram) injected into the eyes of young chickens irreversibly inhibit axonal transport of material labelled with [3H]fucose. This is due to almost total destruction of the retinal ganglion cells, while other retinal cell types, including the displaced amacrine cells found i...

journal_title：Neuroscience letters

authors： Morgan IG

更新日期：1981-07-17 00:00:00

abstract：:Methyl-CpG binding protein 2 (MECP2) is a chromosome-binding protein that regulates the development and maintenance of brain circuits. Altered function of the protein product of MECP2 plays an important role in the etiology of many neurodevelopmental disorders. Mutations involving a loss of function are implicated in ...

journal_title：Neuroscience letters

authors： Tropea D,Mortimer N,Bellini S,Molinos I,Sanfeliu A,Shovlin S,McAllister D,Gill M,Mitchell K,Corvin A

更新日期：2016-05-16 00:00:00