Dynamics of mu-rhythm suppression caused by median nerve stimulation: a magnetoencephalographic study in human subjects.

Abstract:

:We studied event-related desynchronization (ERD) of the 8-13 Hz rhythm (mu rhythm) of the primary somatosensory cortex (SI) caused by contra- and ipsilateral median-nerve stimulation. We used whole-head magnetoencephalography (MEG) and wavelet analysis together with our newly developed color-coded single-trial ERD display. The somatosensory stimuli suppressed mu rhythm at both contra- and ipsilateral SI, but the attenuation was clearly lateralized, being at least 20% stronger contra- than ipsilaterally. Moreover, repeated stimulation significantly reduced mu-rhythm ERD in the ipsilateral but not in the contralateral hemisphere in the course of the experiment. The observed lateralization is in agreement with the classical concept of a dominant role of the contralateral hemisphere in the processing of somatosensory information. The strong ipsilateral ERD in the beginning of the experiment may reflect the presence of non-specific arousal-like activation, which attenuates toward the end of the experiment.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Nikouline VV,Linkenkaer-Hansen K,Wikström H,Kesäniemi M,Antonova EV,Ilmoniemi RJ,Huttunen J

doi

10.1016/s0304-3940(00)01562-7

keywords:

subject

Has Abstract

pub_date

2000-11-24 00:00:00

pages

163-6

issue

3

eissn

0304-3940

issn

1872-7972

pii

S0304394000015627

journal_volume

294

pub_type

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