Differential expression of nicotinamide adenine dinucleotide phosphate-diaphorase in hypothalamic areas of obese Zucker rats.

abstract：:The human basal forebrain has been known to contain many neurons immunoreactive (ir) to tyrosine hydroxylase (TH; the first dopamine-synthesizing enzyme). We examined whether these neurons might contain aromatic L-amino acid decarboxylase (AADC; the second step dopamine-synthesizing enzyme) by dual labeling immunohist...

journal_title：Neuroscience letters

authors： Ikemoto K,Nagatsu I,Kitahama K,Jouvet A,Nishimura A,Nishi K,Maeda T,Arai R

更新日期：1998-02-27 00:00:00

abstract：:The influence of transient forebrain ischemia on the temporal alteration of NMDA receptor (NMDAR1) mRNAs in the hippocampal formation was analysed by in situ hybridization, RNA blot and in vitro receptor autoradiography ([3H]3-((+)2-carboxypiperazin-4-yl)-propyl-1- phosphonic acid). In the CA1 subfield of the hippocam...

journal_title：Neuroscience letters

authors： Sugimoto A,Takeda A,Kogure K,Onodera H

更新日期：1994-03-28 00:00:00

abstract：:Double retrograde axonal tracers (horseradish peroxidase, (HRP) and [3H]apo-HRP) have been used to study the distribution of labeled cells in the cat claustrum. Paired injections were made into different fields of the visual cortical areas. Although the areas of distribution of single-labeled claustral neurons from di...

journal_title：Neuroscience letters

authors： Norita M

更新日期：1983-03-28 00:00:00

abstract：:The nitric oxide synthase (NOS) inhibitor L-nitroarginine methyl ester has been found to exhibit antinociceptive activity in a rat model of pain [Kitto, K.F. et al., Neurosci. Lett., 148 (1992) 1-5; Lee, J.H. et al., NeuroReport, 3 (1992) 841-844; Moore, P.K. et al., Br. J. Pharmacol., 102 (1991) 198-202]. We investig...

journal_title：Neuroscience letters

authors： Lam HH,Hanley DF,Trapp BD,Saito S,Raja S,Dawson TM,Yamaguchi H

更新日期：1996-06-07 00:00:00

abstract：:The pathological basis for essential tremor (ET) is unknown. We used proton magnetic resonance spectroscopic imaging (1H MRSI) in 16 ET patients and 11 controls to measure levels of intracellular metabolites, including N-acetyl-L-aspartate (NAA) and total choline, relative to total creatine (tCR), in several brain reg...

journal_title：Neuroscience letters

authors： Louis ED,Shungu DC,Chan S,Mao X,Jurewicz EC,Watner D

更新日期：2002-11-15 00:00:00

abstract：:Ibotenic acid was injected in the lateral geniculate nucleus of cats to investigate the suitability of the technique in studies involving anterograde degeneration in the thalamo-cortical pathway when it is important not to damage fibres of passage at the lesion site. Small injections cause localized degeneration of ne...

journal_title：Neuroscience letters

authors： Garey LJ,Hornung JP

更新日期：1980-09-01 00:00:00

abstract：:Alpha-2 macroglobulin (A2M) is a serum pan-protease inhibitor that is related with the pathogenesis of Alzheimer's disease (AD) through its ability to mediate amyloid beta degradation. Recently, it has been reported that the I1000V polymorphism in A2M gene might increase the risk of AD. In the present study, we invest...

journal_title：Neuroscience letters

authors： Shibata N,Ohnuma T,Takahashi T,Ohtsuka E,Ueki A,Nagao M,Arai H

更新日期：2000-08-25 00:00:00

abstract：:An increase in the arthritis index as a marker of chronic inflammation and suppression of food intake are observed in adjuvant arthritic (AA) rats. Our previous study demonstrated that central oxytocin (OXT)-ergic pathways were activated potently in AA rats. In the present study, OXT-saporin (SAP) cytotoxin, which che...

journal_title：Neuroscience letters

authors： Matsuura T,Kawasaki M,Hashimoto H,Yoshimura M,Motojima Y,Saito R,Ueno H,Maruyama T,Sabanai K,Mori T,Ohnishi H,Sakai A,Ueta Y

更新日期：2016-05-16 00:00:00

abstract：:During horizontal optokinetic stimulation (moving random dot pattern) in freely standing cats, gaze, head, and eye movements were measured with the search coil technique. The position values ('beating field') were evaluated. Gaze position depended on stimulus direction and stimulus velocity; it shifted to where the st...

journal_title：Neuroscience letters

authors： Schweigart G

更新日期：1995-01-02 00:00:00

abstract：:This study used ERPs to determine whether older adults use prosody in resolving early and late closure ambiguities comparably to young adults. Participants made off-line acceptability judgments on well-formed sentences or those containing prosody-syntax mismatches. Behaviorally, both groups identified mismatches, but ...

journal_title：Neuroscience letters

authors： Steinhauer K,Abada SH,Pauker E,Itzhak I,Baum SR

更新日期：2010-03-19 00:00:00

abstract：:The effect of bifemelane hydrochloride (BFH) on the induction of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient global ischemia in gerbil brain was investigated by in situ hybridization using cloned cDNA probes selective for each mRNA species. Following 3.5 min of ischemia, H...

journal_title：Neuroscience letters

authors： Aoki M,Abe K,Liu XH,Lee TH,Kato H,Kogure K

更新日期：1993-05-14 00:00:00

abstract：:Considerable evidence suggests that low (picomolar) concentrations of the HIV-1 envelope glycoprotein gp120 induce neuronal cell death by stimulating the release of microglial toxins, which in turn activate N-methyl-D-aspartate (NMDA) receptors. Conversely, high (micromolar) concentrations of gp120 have been reported ...

journal_title：Neuroscience letters

authors： Wittekindt B,Betz H,Laube B

更新日期：2000-02-18 00:00:00

abstract：:The morphology and function of sciatic nerve were investigated in spontaneously hypertensive rats (SHR), either control or hydralazine-treated, and in normotensive Wistar Kyoto rats of 6 months of age. In control SHR decreased percentages of class I fibers (20-15 microm in diameter), of axonal NFP-H 200 kDa neurofilam...

journal_title：Neuroscience letters

authors： Tomassoni D,Traini E,Vitaioli L,Amenta F

更新日期：2004-05-20 00:00:00

abstract：:The association between (GT)n dinucleotide repeats in monoamine oxidase gene loci, monoamine oxidase A (MAOA) and B (MAOB), and Parkinson's disease (PD), Alzheimer's disease (AD), and Lewy body variant (LBV) of AD were determined. MAOA-GT polymorphisms were significantly associated with pure AD and LBV. MAOA-GT allele...

journal_title：Neuroscience letters

authors： Takehashi M,Tanaka S,Masliah E,Ueda K

更新日期：2002-07-19 00:00:00

abstract：:The expression of class I and class II histocompatibility antigens by myelin basic protein (MBP)-positive oligodendrocytes, in response to exogenous cytokines, has been investigated in vitro. It has been found that interferon-gamma (IFN-gamma), although capable of class I induction, does not induce class II on oligode...

journal_title：Neuroscience letters

authors： Turnley AM,Miller JF,Bartlett PF

更新日期：1991-02-11 00:00:00

abstract：:Mutations in presenilins are the major cause of early onset familial Alzheimer disease. It has recently been argued that clinical presenilin mutations work as loss-of-function but not toxic gain-of-function. To investigate whether presenilins are involved in the regulation of the distribution of neuronal membrane lipi...

journal_title：Neuroscience letters

authors： Oikawa N,Goto M,Ikeda K,Taguchi R,Yanagisawa K

更新日期：2012-09-06 00:00:00

abstract：:By using intracellular deposition of horseradish peroxidase (HRP), a method has been designed for combined light and electron microscopic tracing of single fibers and synaptic terminals, belonging to physiologically characterized neurons. This technique has been successfully tested on the axon collateral systems of ca...

journal_title：Neuroscience letters

authors： Cullheim S,Kellerth JO

更新日期：1976-08-01 00:00:00

abstract：:This study investigated the effects of dementia on standing postural adaptation during performance of a visual search task. We recruited 16 older adults with dementia and 15 without dementia. Postural sway was assessed by recording medial-lateral (ML) and anterior-posterior (AP) center-of-pressure when standing with a...

journal_title：Neuroscience letters

authors： Jor'dan AJ,McCarten JR,Rottunda S,Stoffregen TA,Manor B,Wade MG

更新日期：2015-04-23 00:00:00

abstract：:The axonal efferents of neurons of the supraoptic nucleus area were studied by radioautography in the rat after discrete stereotaxic injections of [3H]leucine into this nucleus. Beside a densely labeled pathway running from the nucleus to the posterior pituitary through the internal median eminence, several of the vis...

journal_title：Neuroscience letters

authors： Alonso G,Szafarczyk A,Assenmacher I

更新日期：1986-05-23 00:00:00

abstract：:In the present study, we tried to examine whether the 2-deoxy-D-[14C]glucose (2-DG) technique is useful to investigate the metabolic activity of fetal rat brain in the maternal uterus. The result shows that metabolic mapping of the fetal brain was clearly obtained by means of the 2-DG technique. ...

journal_title：Neuroscience letters

authors： Morimoto A,Imai-Matsumura K,Murakami N

更新日期：1990-03-26 00:00:00

abstract：:Chronic stress is well known to exacerbate pain. We tested the hypothesis that neonatal handling, which induces resilience to the negative impact of stress by increasing the quality and quantity of maternal care, attenuates the mechanical hyperalgesia produced by water-avoidance stress in the adult rat. Neonatal male ...

journal_title：Neuroscience letters

authors： Alvarez P,Levine JD,Green PG

更新日期：2015-03-30 00:00:00

abstract：:Inattention and impulsivity are the two most important indices for evaluations of ADHD. Currently, inattention and impulsivity were evaluated by clinical scales. The intelligent evaluation of the two indices using machine learning remains largely unexplored. This paper aimed to build regression modes for inattention a...

journal_title：Neuroscience letters

authors： Wang XH,Xu J,Li L

更新日期：2020-04-17 00:00:00

abstract：:Many studies have shown that acupuncture can contribute to the biochemical balance in the central nervous system and maintenance or recovery of homeostasis. It is well known that chronic administration of ethanol may produce depletion or sensitization of extracellular dopamine levels in the nucleus accumbens. The pres...

journal_title：Neuroscience letters

authors： Zhao RJ,Yoon SS,Lee BH,Kwon YK,Kim KJ,Shim I,Choi KH,Kim MR,Golden GT,Yang CH

更新日期：2006-02-27 00:00:00

abstract：:Cutaneous Meissner corpuscles depend for development and survival exclusively on the NT system TrkB/BDNF/NT-4 unlike other types of sensory corpuscles and nerve endings, which have very complex neuronal and growth factor dependence. However, the pattern of expression of TrkB in human Meissner corpuscles is not known. ...

journal_title：Neuroscience letters

authors： Calavia MG,Feito J,López-Iglesias L,de Carlos F,García-Suarez O,Pérez-Piñera P,Cobo J,Vega JA

更新日期：2010-01-04 00:00:00

abstract：:Among various kinds of visual motion, wide field coherent visual motion should have characteristic physiological significance regarding the relationship between the external world and us. To detect veridical visual motion in the surrounding environment, specific mechanisms are necessary to differentiate it from the wi...

journal_title：Neuroscience letters

authors： Urakawa T,Inui K,Kakigi R

更新日期：2011-01-25 00:00:00

abstract：:Gabaculine, a conformationally restricted analogue of GABA, is (i) a moderately potent inhibitor (IC(50) 69 muM) of the sodium-dependent uptake of GABA in rat brain slices, (ii) ineffective at 100 muM as an inhibitor of the sodium-independent binding of GABA to membranes from rat brain, (iii) a relatively weak inhibit...

journal_title：Neuroscience letters

authors： Allan RD,Johnston GA,Twitchin B

更新日期：1977-01-01 00:00:00

abstract：:Neuroimmune mechanisms play critical roles in brain development and can be impacted by early life adversity. Microglia are the resident immune cells in the brain, with both sex-specific and region-specific developmental profiles. Since early life adversity is associated with several neuropsychiatric disorders with dev...

journal_title：Neuroscience letters

authors： Gildawie KR,Orso R,Peterzell S,Thompson V,Brenhouse HC

更新日期：2020-11-01 00:00:00

abstract：:The majority of previous studies which have explored the mechanisms underlying perception of the direction of gravity in static roll tilt have proposed that the tendency to estimate the subjective visual vertical (SVV) as tilted towards body tilt ('Aubert effect') arises from an underestimation of perceived body tilt....

journal_title：Neuroscience letters

authors： Ceyte H,Cian C,Trousselard M,Barraud PA

更新日期：2009-10-02 00:00:00

abstract：:Constant bright light (LL) suppresses 24-h melatonin and many other behavioral and physiological rhythms in pigeons. LL also strongly suppresses sleep. Daily melatonin infusions in LL restore sleep to normal nocturnal levels of a light-dark cycle and continuous infusions sustain it for at least 10 days. Restoration of...

journal_title：Neuroscience letters

authors： Phillips NH,Berger RJ

更新日期：1992-10-12 00:00:00

abstract：:Several evidences indicate that PPARgamma stimulation promotes neuronal differentiation. However, to date, no data describe the effects of PPARgamma agonists on neurite outgrowth. Here we have evaluated the effects of pioglitazone, a synthetic PPARgamma agonist, on differentiation and neurite outgrowth in SH-SY5Y huma...

journal_title：Neuroscience letters

authors： Miglio G,Rattazzi L,Rosa AC,Fantozzi R

更新日期：2009-04-24 00:00:00