Neonatal handling (resilience) attenuates water-avoidance stress induced enhancement of chronic mechanical hyperalgesia in the rat.

abstract：:The effect of sex, postmortem delay and aging on alpha 2-adrenoceptor binding was studied in tissue sections from several representative regions of the human brain from 21 subjects using [3H]UK-14304 as a ligand. Sex and postmortem delay did not influence the density of alpha 2-receptors. Aging resulted in clear decre...

journal_title：Neuroscience letters

authors： Pascual J,del Arco C,González AM,Díaz A,del Olmo E,Pazos A

更新日期：1991-12-09 00:00:00

abstract：:Neuronal cell cycle activation has been implicated in neurodegenerative diseases such as Alzheimer's disease, while the initiating mechanism of cell cycle activation remains to be determined. Interestingly, our previous studies have shown that cell cycle activation by c-Myc (Myc) leads to neuronal cell death which sug...

journal_title：Neuroscience letters

authors： Lee HP,Kudo W,Zhu X,Smith MA,Lee HG

更新日期：2011-11-14 00:00:00

abstract：:In the present study we investigated the effect of electrolytic lesion of the medial septal area (MSA) on the dipsogenic, natriuretic, kaliuretic and pressor responses elicited by intracerebroventricular (i.c.v.) injection of the cholinergic agonist carbachol. Freely moving rats with sham or MSA lesion (1-7 days and 1...

journal_title：Neuroscience letters

authors： Luiz AC,Saad WA,Camargo LA,Renzi A,De Luca Junior LA,Menani JV

更新日期：1991-11-11 00:00:00

abstract：:Neuroglobin (Ngb) is a novel vertebrate globin expressed principally in neurons. Ngb expression is induced by hypoxia and ischemia, and Ngb protects neurons against these insults. The mechanism of Ngb's protective action is unknown, but its ability to bind NO suggests that NO scavenging might be involved. To test this...

journal_title：Neuroscience letters

authors： Jin K,Mao XO,Xie L,Khan AA,Greenberg DA

更新日期：2008-01-10 00:00:00

abstract：:Recent studies have described the role of various regions of the neural cell adhesion molecule (NCAM) in cell-cell interactions. Monoclonal antibodies (L2/HNK-1) directed against a sulfated, glucuronic acid-containing, N-linked carbohydrate epitope have also been shown to inhibit NCAM-mediated neural cell adhesion. In...

journal_title：Neuroscience letters

authors： Cole GJ,Schachner M,Fliesler SJ

更新日期：1988-11-11 00:00:00

abstract：:trk receptors are downregulated in both dorsal root ganglion (DRG) and spinal motoneurons of aged rats with behavioral sensorimotor deficits. Here we provide evidence, using reverse transcription-polymerase chain reaction (RT-PCR), of decreased levels of neurotrophin (nerve growth factor, NGF; brain-derived neurotroph...

journal_title：Neuroscience letters

authors： Ming Y,Bergman E,Edström E,Ulfhake B

更新日期：1999-10-08 00:00:00

abstract：:The levels of apoptosis associated proteins Bcl(2), Bax, cytochrome-c and p53 was investigated in mice cerebral cortex and cerebellum, using an experimental model of fatal murine cerebral malaria (FMCM). Owing to the activation of events central to mitochondrial dysfunctions, we monitored the structural integrity of m...

journal_title：Neuroscience letters

authors： Kumar KA,Babu PP

更新日期：2002-09-06 00:00:00

abstract：:Interleukin-18 (IL-18) is a pro-inflammatory cytokine and an important mediator of peripheral inflammation and host immune response. IL-18 functions through its binding with the IL-18 receptor (IL-18R), which consists of two chains, an IL-18-binding α chain (IL-18Rα) and a signaling β chain. IL-18 and IL-18R are expre...

journal_title：Neuroscience letters

authors： Kuwahara-Otani S,Maeda S,Kobayashi K,Minato Y,Tanaka K,Yamanishi K,Hata M,Li W,Hayakawa T,Noguchi K,Okamura H,Yagi H

更新日期：2017-05-22 00:00:00

abstract：:Neurotrophins are a family of growth factor primarily acting in the nervous system, throughout two categories of membrane receptors on the basis of their high (Trk receptors) or low (p75NTR) affinity. Both neurotrophins and Trk receptors are phylogenetically conserved and are expressed not only in the central and peri...

journal_title：Neuroscience letters

authors： Abbate F,Guerrera MC,Montalbano G,Levanti MB,Germanà GP,Navarra M,Laurà R,Vega JA,Ciriaco E,Germanà A

更新日期：2014-03-20 00:00:00

abstract：:It is known that alcohol induces disorders in the metabolism of retinoids and particularly in the biosynthetic pathways of retinoic acid (RA). Since RA has, along with other hormones and particularly triiodothyronine (T3), a physiological role in the adult brain, the effect of chronic exposure to alcohol on RA and T3 ...

journal_title：Neuroscience letters

authors： Alfos S,Higueret P,Pallet V,Higueret D,Garcin H,Jaffard R

更新日期：1996-03-15 00:00:00

abstract：:Sexual receptivity was suppressed in female rats immediately after the male had ejaculated. The inhibition was prevented by intravaginal injection of naloxone (100 micrograms) before testing and intravaginal injection of beta-endorphin (1.0 micrograms) inhibited sexual behavior in female rats in a manner comparable to...

journal_title：Neuroscience letters

authors： Forsberg G,Bednar I,Eneroth P,Södersten P

更新日期：1990-07-17 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disease characterized by degeneration and death of motor neurons. Aberrant protein aggregation and oxidative stress are implicated in the etiology of ALS; thus preventing propagation of early aggregation events and oxidative damage could be an...

journal_title：Neuroscience letters

authors： Evans TM,Bhattacharya A,Shi Y,Qi W,Block TJ,Chaudhuri A,Chaudhuri AR,Hawker K,Van Remmen H

更新日期：2016-06-15 00:00:00

abstract：:Estrogen not only modulates nigrostriatal function but also developmental processes in the striatum. Recently, we have demonstrated the presence of the estrogen-synthesizing enzyme aromatase in the developing mouse striatum. This study is concerned with the expression of estrogen receptor-alpha/beta (ER) mRNA in the d...

journal_title：Neuroscience letters

authors： Küppers E,Beyer C

更新日期：1999-12-03 00:00:00

abstract：:Two types of cone horizontal cells were identified morphologically in the retina of a trichromatic fish by fluorescent labelling with Lucifer Yellow and confocal laser scanning microscopy. H1 cells are located adjacent to the outer plexiform layer, have large somata, small dendritic fields, and contact all cone types....

journal_title：Neuroscience letters

authors： Braun SC,Kröger RH,Wagner HJ

更新日期：1997-10-17 00:00:00

abstract：:The neurotoxicity of the glutamate receptor agonists N-methyl-D-aspartate (NMDA), (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA), and kainate was quantitatively assessed in murine spinal cord and cortical cultures prepared under identical conditions. Compared with cortical neurons, spinal neuron...

journal_title：Neuroscience letters

authors： Regan RF

更新日期：1996-07-26 00:00:00

abstract：:Cellular locations, axonal projections, and synaptic effects of inhibitory vestibulocollic (VC) neurons activated by the ampullary nerve of the posterior semicircular canal (PCN) were studied in anesthetized cats. The inhibitory VC neurons were identified by their monosynaptic responses to PCN stimulation and by their...

journal_title：Neuroscience letters

authors： Isu N,Sakuma A,Hiranuma K,Ichikawa T,Uchino Y

更新日期：1990-11-13 00:00:00

abstract：:The neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal total biopterin were examined both in rats and mice at different time courses. Results indicate that MPTP caused a significant decrease of total biopterin content in the striatum of mice. This effect occurred as soon as 6 h after...

journal_title：Neuroscience letters

authors： Lee EH

更新日期：1988-06-07 00:00:00

abstract：:In urethane-anesthetized rats, injections of 50 pmol of arginine-vasopressin (AVP) or thyrotropin-releasing hormone (TRH) into a lateral cerebral ventricle (i.c.v.) elicit short-latency increases in blood pressure. i.c.v. injection of 50 pmol of the AVP antagonist, d(CH2)5Tyr(Me)AVP, but not of the vehicle (artificial...

journal_title：Neuroscience letters

authors： Pittman QJ,Franklin LG

更新日期：1985-05-14 00:00:00

abstract：:It remains unknown if tissue acidosis contributes to neuronal loss during cerebral ischemia. We report that brief intracellular acidification (pH 6.62) results in delayed neuronal loss in cultured hippocampal slices. Cell loss was located primarily in stratum pyramidale and the hilus suggesting that neurons were prefe...

journal_title：Neuroscience letters

authors： Shen H,Chan J,Kass IS,Bergold PJ

更新日期：1995-02-09 00:00:00

abstract：:Drug addiction is a process that transits from recreative and regular drug use into compulsive drug use. The two patterns of drug use, controlled drug intake and escalated drug intake, represent different stages in the development of drug addiction; and escalation of drug use is a hallmark of addiction. Accumulating s...

journal_title：Neuroscience letters

authors： Du HY,Cao DN,Chen Y,Wang L,Wu N,Li J

更新日期：2016-01-12 00:00:00

abstract：:L-Histidine decarboxylase catalyzes the formation of histamine from the amino acid L-histidine. We have studied the distribution of neurons expressing mRNA for histidine decarboxylase in adult rat brain using in situ hybridization with synthetic oligonucleotide probes. The expression of mRNA for histidine decarboxylas...

journal_title：Neuroscience letters

authors： Castrén E,Panula P

更新日期：1990-11-27 00:00:00

abstract：:Previously we have shown that the 6-sulphatoxymelatonin rhythm of oil rig workers on a 2-week night shift (1800-0600 h) adapts to the shift via a phase delay. We now report the findings of a study on two offshore drill crews working a 1 week day (1200-0000 h), 1 week night (0000-1200 h) swing shift. Urine samples were...

journal_title：Neuroscience letters

authors： Barnes RG,Forbes MJ,Arendt J

更新日期：1998-08-21 00:00:00

abstract：:Reactive oxygen species (ROS) are implicated in the pathogenesis of multiple sclerosis (MS) and its murine model experimental autoimmune encephalomyelitis (EAE). The effect of edaravone, a free radical scavenger, on EAE was investigated in this study. Treatment with edaravone significantly ameliorated the clinical sev...

journal_title：Neuroscience letters

authors： Moriya M,Nakatsuji Y,Miyamoto K,Okuno T,Kinoshita M,Kumanogoh A,Kusunoki S,Sakoda S

更新日期：2008-08-08 00:00:00

abstract：:The projection of the substantia nigra-ventral tegmental area (SN-VTA) to the ipsilateral and contralateral caudate-putamen was studied with double-labeling fluorescence techniques in the albino rat. By combining glyoxylic acid histofluorescence with retrograde fluorescence tracers, we were able to determine that 93% ...

journal_title：Neuroscience letters

authors： Fallon JH,Wang C,Kim Y,Canepa N,Loughlin S,Seroogy K

更新日期：1983-10-10 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) has been proposed as a key regulator and mediator of long-term synaptic modifications related to learning and memory maintenance. Our previous studies show that application of high-frequency stimulation (HFS) sufficient to elicit LTP at the dentate gyrus (DG)-CA3 pathway produc...

journal_title：Neuroscience letters

authors： Gómez-Palacio-Schjetnan A,Escobar ML

更新日期：2008-11-07 00:00:00

abstract：:Propofol has been demonstrated as a drug of abuse in humans. Our previous study indicated that dexamethasone, a potent agonist of glucocorticoid receptor (GR), inhibited propofol-maintained rat self-administration behaviors by systematic injection. However, the direct effect of GR in the nucleus accumbens (NAc) on pro...

journal_title：Neuroscience letters

authors： Wu B,Lin W,Wang H,Abdullah T,Wang B,Su Y,Ge RS,Lian Q

更新日期：2018-01-01 00:00:00

abstract：:Glutamatergic system, the main stimulating system of the brain, plays an important role in the pathogenesis of schizophrenia. Hippocampus, a structure crucial for memory and cognitive functions and rich in glutamatergic neurons, is a natural object of interest in studies on psychoses. Sarcosine, a glycine transporter ...

journal_title：Neuroscience letters

authors： Strzelecki D,Podgórski M,Kałużyńska O,Gawlik-Kotelnicka O,Stefańczyk L,Kotlicka-Antczak M,Gmitrowicz A,Grzelak P

更新日期：2015-10-08 00:00:00

abstract：:The contribution of NMDA receptors to neuronal hyperexcitability following in vitro ethanol withdrawal was examined using afterdischarges (ADs) in rat dentate gyrus as a model system. ADs were evoked by high frequency stimuli and blocked by N-methyl-D-aspartate (NMDA) receptor antagonists. Ethanol (75 mM) inhibited AD...

journal_title：Neuroscience letters

authors： Morrisett RA

更新日期：1994-02-14 00:00:00

abstract：:Neurons in the ipsilateral anteropolar division of the zona incerta were retrogradely labeled following injections of horseradish peroxidase in the main olfactory bulb. In addition, labeled cell bodies were found in the dorsal hypothalamus. Fewer and less densely labeled neuron cell bodies were seen in the contralater...

journal_title：Neuroscience letters

authors： Uemura-Sumi M,Osterstock J,Millhouse OE

更新日期：1985-02-04 00:00:00

abstract：:Fatigue of the lumbar extensor muscles has been associated with a degradation of balance, but the mechanism is not well understood. The ankle plays a major role in upright standing, and loss of proprioceptive acuity at the ankle could contribute to a degradation of balance. Therefore, the first objective of this study...

journal_title：Neuroscience letters

authors： Pline KM,Madigan ML,Nussbaum MA,Grange RW

更新日期：2005-12-16 00:00:00