Hepatocyte growth factor suppresses ischemic cerebral edema in rats with microsphere embolism.

abstract：:The effect of calcium on the biogenic amine level and distribution in the mouse brain was investigated by a histochemical method using a microscopic photometer (Pl, Nikon). Histochemical fluorescence intensities in the corpus striatum and cortex cerebri regions were significantly increased by the intraventricular admi...

journal_title：Neuroscience letters

authors： Sutoo D,Akiyama K

更新日期：1986-08-15 00:00:00

abstract：:Focal brain lesions such as cortical dysplasia and glioneural tumors generate epileptic activity and thus may be synaptically connected with normal cortex. To test this hypothesis, we compared event-related potentials recorded directly from the medial temporal lobe (MTL) and a dysplastic lesion in eight patients with ...

journal_title：Neuroscience letters

authors： Kirschstein T,Fernández G,Grunwald T,Pezer N,Urbach H,Blümcke I,Van Roost D,Lehnertz K,Elger CE

更新日期：2003-03-06 00:00:00

abstract：:beta-Amyloid protein immunoreactivity in neocortex and hippocampus of Alzheimer's disease and control brains has been measured using an automatic image analysis system. Successive fields from the pial surface to white matter in 4 neocortical sites, parahippocampal gyrus and along the pyramidal cell layer in the hippoc...

journal_title：Neuroscience letters

authors： Cairns NJ,Chadwick A,Luthert PJ,Lantos PL

更新日期：1991-08-05 00:00:00

abstract：:During normal post-hatch development and maturation in chicken forebrain there was a doubling in the average thickness of the post-synaptic densities (PSDs) in isolated synaptosomes, but no change in the average length of synaptic junctions. In the same period the concentration of the major post-synaptic density prote...

journal_title：Neuroscience letters

authors： Rostas JA,Brent VA,Güldner FH

更新日期：1984-04-06 00:00:00

abstract：:The effects of the N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists MK-801 and NBQX, respectively, on salivary secretion and retching induced by vagal stimulation were studied in decerebrate dogs. Vagal stimulation induced an increase in salivary secretion and fictive retching. Intra-4th ventricular appli...

journal_title：Neuroscience letters

authors： Furukawa N,Hatano M,Fukuda H,Koga T

更新日期：1998-12-11 00:00:00

abstract：:Human amniotic epithelial (HAE) cells have been used for allotransplantation in patients with lysosomal storage disease due to lack of expression of HLA antigens. Previously, we have reported the expression of differentiation markers for both neural stem cells, and neuron and glial cells. In the present study, we inve...

journal_title：Neuroscience letters

authors： Sakuragawa N,Misawa H,Ohsugi K,Kakishita K,Ishii T,Thangavel R,Tohyama J,Elwan M,Yokoyama Y,Okuda O,Arai H,Ogino I,Sato K

更新日期：1997-08-22 00:00:00

abstract：:Gap junctions between neurons contribute to synchronous neuronal firing and may play a role in the pathophysiology of epilepsy. We examined the expression of a number of gap junction subunits, including the neuronal gap junction forming protein connexin36 (Cx36), in the hippocampus at various time points following an ...

journal_title：Neuroscience letters

authors： McCracken CB,Roberts DC

更新日期：2006-09-11 00:00:00

abstract：:Patch-clamp pipettes filled with 50-5000 microM glutamate were placed on crayfish muscle fibers treated with collagenase, formed G omega seals and elicited single-channel currents with a main amplitude of about -8 pA at -70 mV membrane potential, representing a conductance of about 100 pS (19 degrees C). Evaluation of...

journal_title：Neuroscience letters

authors： Franke C,Dudel J

更新日期：1985-09-06 00:00:00

abstract：:Neuroimaging studies have identified cognitive tasks that can selectively activate specific parts of the brains. However, the subsequent effect of localized brain activation on the cognitive functioning remains unclear. We discovered that after being engaged in the novel picture encoding task to activate hippocampus f...

journal_title：Neuroscience letters

authors： Chan AS,Cheung M,Ho Y,Jing He W

更新日期：2000-04-07 00:00:00

abstract：:Long-term potentiation (LTP) in the dentate gyrus was previously shown to be enhanced by nicotine, an effect dependent on both homomeric α7 and heteromeric α2β2 nicotinic acetylcholine receptors (nAChR). In our experiments, bath-applied nicotine produced no significant enhancement of LTP. The α7 nAChR silent agonist N...

journal_title：Neuroscience letters

authors： Papke RL,Peng C,Kumar A,Stokes C

更新日期：2018-06-11 00:00:00

abstract：:Adenosine triphosphate (ATP) is well known to be released from injured or inflamed tissues, and to excite/sensitize nociceptors in response to heat and mechanical stimulation. To determine whether muscle releases ATP when it is compressed, we measured ATP release from the extensor digitorum longus muscle (EDL). In add...

journal_title：Neuroscience letters

authors： Taguchi T,Kozaki Y,Katanosaka K,Mizumura K

更新日期：2008-04-04 00:00:00

abstract：:The cellular location of kappa-opioid binding sites in the guinea pig cerebellum has been investigated. kappa-Opioid sites were labelled using [3H]ethylketocyclazocine in the presence of mu- and delta-blocking ligands. In vitro autoradiography demonstrated that this kappa-opioid binding was localized predominantly in ...

journal_title：Neuroscience letters

authors： Bunn SJ,Wilkin GP

更新日期：1988-01-11 00:00:00

abstract：:In order to characterise primary central nervous system lymphomas (PCNSL) and to evaluate if 1H spectroscopy improves the preoperative differential diagnosis of PCNSL and glioma, seven immunocompetent patients with PCNSL and 21 patients with glioma were examined using single voxel, short echo time magnetic resonance s...

journal_title：Neuroscience letters

authors： Harting I,Hartmann M,Jost G,Sommer C,Ahmadi R,Heiland S,Sartor K

更新日期：2003-05-22 00:00:00

abstract：:We investigated the relation between visual feedback and the degree of structure versus randomness in the variability of single-digit, isometric force output. Participants were instructed to maintain a constant level of force during the presence or absence of visual feedback about force output. The structure of force ...

journal_title：Neuroscience letters

authors： Athreya DN,Van Orden G,Riley MA

更新日期：2012-03-28 00:00:00

abstract：:We have investigated the effect of histamine (HA) on spontaneous firing of dopaminergic (DA) and GABAergic neurons in the substantia nigra (SN) and the ventral tegmental area (VTA) of the rat in vitro. Single-unit extracellular recordings were obtained and drugs were bath applied. In both regions application of HA (10...

journal_title：Neuroscience letters

authors： Korotkova TM,Haas HL,Brown RE

更新日期：2002-03-08 00:00:00

abstract：:Basal serotonin (5-HT) release, measured in the presence of imipramine, was significantly reduced in slices of hippocampus, n. accumbens and frontal cortex from rats subjected to forced swim test and chronic isolation. Only in the hippocampus, in the two animal models of depression, K-stimulated release was increased....

journal_title：Neuroscience letters

authors： Jaffe EH,De Frias V,Ibarra C

更新日期：1993-11-12 00:00:00

abstract：:The norepinephrine (NE) and dopamine (DA) content of the cat carotid body (CB) in vivo was investigated under normoxic and hypoxic conditions (5% O2 for 1 h) by radiolabelling method. To avoid a large scattering of the measured values due to inhomogeneity of the biological material, young sib animals were used. The me...

journal_title：Neuroscience letters

authors： Starlinger H,Acker H

更新日期：1986-02-14 00:00:00

abstract：:The nucleus raphe magnus belongs to the thermoafferent system. Following iontophoretic choleratoxin b injections in its rostral part, a substantial to large number of anterogradely labeled varicose fibres were observed in the medial and lateral preoptic areas, the bed nucleus, the substantia innominata, the ventral pa...

journal_title：Neuroscience letters

authors： Hermann DM,Luppi PH,Peyron C,Hinckel P,Jouvet M

更新日期：1996-10-04 00:00:00

abstract：:Silent synapses display no excitatory post-synaptic currents (EPSCs) at resting potentials, but can conduct at depolarized potentials. In the hippocampal CA1 region of young animals, conversion of silent synapses to functional synapses occurs rapidly after pairing post-synaptic depolarization with 1Hz pre-synaptic sti...

journal_title：Neuroscience letters

authors： Kasten MR,Fan Y,Schulz PE

更新日期：2007-04-24 00:00:00

abstract：:Recent imaging studies have reported the projection of semicircular canal signals onto wide regions of the cerebral cortex but little is known about otolith projections onto the cerebral cortex. We used functional magnetic resonance imaging (fMRI) to investigate the activation of the cortex by loud clicks that selecti...

journal_title：Neuroscience letters

authors： Miyamoto T,Fukushima K,Takada T,de Waele C,Vidal PP

更新日期：2007-08-09 00:00:00

abstract：:The effect of electrical stimulation of the dorsal hippocampus on accumbens dopamine release was examined. Stimulation of the kindled hippocampus that produced stage 3 seizures evoked a brief increase in extracellular DA and DOPAC levels in the contralateral nucleus accumbens. In contrast, similar stimulation early in...

journal_title：Neuroscience letters

authors： Strecker RE,Moneta ME

更新日期：1994-08-01 00:00:00

abstract：:The anatomical distribution of insulin-degrading enzyme (IDE) was studied in normal and Alzheimer's disease (AD) human brains. By use of a monospecific, polyclonal antiserum against the enzyme we identified IDE antigen in multiple cortical and subcortical neurons. Glia did not show IDE immunoreactivity. In AD brains i...

journal_title：Neuroscience letters

authors： Bernstein HG,Ansorge S,Riederer P,Reiser M,Frölich L,Bogerts B

更新日期：1999-03-26 00:00:00

abstract：:Curcumin is capable of promoting peripheral nerve regeneration in normal condition. However, it is unclear whether its beneficial effect on nerve regeneration still exists under diabetic mellitus. The present study was designed to investigate such a possibility. Diabetes in rats was developed by a single dose of strep...

journal_title：Neuroscience letters

authors： Ma J,Yu H,Liu J,Chen Y,Wang Q,Xiang L

更新日期：2016-01-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two apparently distinct neurodegenerative diseases, the former characterized by selective loss of motor neurons in the brain and spinal cord and the latter characterized by selective atrophy of frontal and temporal lobes. Over the years, however...

journal_title：Neuroscience letters

authors： Wen X,Westergard T,Pasinelli P,Trotti D

更新日期：2017-01-01 00:00:00

abstract：:The contribution of NMDA receptors to neuronal hyperexcitability following in vitro ethanol withdrawal was examined using afterdischarges (ADs) in rat dentate gyrus as a model system. ADs were evoked by high frequency stimuli and blocked by N-methyl-D-aspartate (NMDA) receptor antagonists. Ethanol (75 mM) inhibited AD...

journal_title：Neuroscience letters

authors： Morrisett RA

更新日期：1994-02-14 00:00:00

abstract：:In recent years, several attempts have been made to identify biochemical and/or genetic markers which might have diagnostic and prognostic uses for Alzheimer's disease (AD). To look for possible new blood markers, a longitudinal study was carried out in our Central Nervous System Biomedical Research Center between Oct...

journal_title：Neuroscience letters

authors： Lombardi VR,Cacabelos R

更新日期：1999-01-22 00:00:00

abstract：:Functionally active N-methyl-D-aspartate (NMDA) receptors on cat medullary respiratory neurones were revealed by local iontophoretic application of DL-2-amino-7-phosphonoheptanoic acid (AP7). Blockade of NMDA receptors by systemic administration of NMDA antagonists (MK-801, phencyclidine, ketamine, AP7) in vagotomized...

journal_title：Neuroscience letters

authors： Foutz AS,Champagnat J,Denavit-Saubié M

更新日期：1988-05-03 00:00:00

abstract：:Cerebellar granule neurons can be maintained in culture in a medium containing high serum and depolarising levels of KCl. When serum is removed and the KCl levels lowered from 25 to 5 mM, the cells undergo apoptosis. Apoptosis can be prevented by inhibitors of transcription or translation, suggesting a need for macrom...

journal_title：Neuroscience letters

authors： Ginham R,Harrison DC,Facci L,Skaper S,Philpott KL

更新日期：2001-04-20 00:00:00

abstract：:The pathogenetic mechanisms leading to progressive neurodegeneration in amyotrophic lateral sclerosis (ALS) have not been fully elucidated. One possible factor responsible for the selective motor neuron loss in the motor cortex, brain stem and spinal cord is glutamate-induced excitotoxicity particularly mediated via a...

journal_title：Neuroscience letters

authors： Petri S,Krampfl K,Hashemi F,Schmalbach S,Grothe C,Hori A,Dengler R,Bufler J

更新日期：2004-04-29 00:00:00

abstract：:The survival of identified retinal ganglion cells (RGGs) in vitro increased when they were plated over subcultured monolayers of astrocytes. Immunofluorescence labelling of these monolayers showed that over 85% of the cells were glial fibrillary acidic protein (GFAP) positive and consisted of large, flat immature astr...

journal_title：Neuroscience letters

authors： McCaffery CA,Raju TR,Bennett MR

更新日期：1985-06-24 00:00:00