The maturation of post-synaptic densities in chicken forebrain.

abstract：:The intergeniculate leaflet (IGL) of the lateral geniculate complex is marked by the presence of neuro-peptide Y-containing neurons that project to the suprachiasmatic nuclei (SCN) of the hypothalamus. In the present study, we demonstrate that both the IGL and SCN in the hamster and rat are specifically delineated by ...

journal_title：Neuroscience letters

authors： Morin LP,Johnson RF,Moore RY

更新日期：1989-04-24 00:00:00

abstract：:Painful vincristine (VCR) neuropathy is a frequent and dose-limiting problem in cancer treatment. Here, we investigated how pain behavior is modulated in mice lacking the serotonin transporter (5-HTT-/- mice) after inducing neuropathy by intraperitoneal injections of VCR. We used standard tests for evoked pain, high p...

journal_title：Neuroscience letters

authors： Hansen N,Uçeyler N,Palm F,Zelenka M,Biko L,Lesch KP,Gerlach M,Sommer C

更新日期：2011-05-16 00:00:00

abstract：:The unensheathed axons in the spinal roots of adult dystrophic mice were examined by freeze-fracture electron microscopy. In most areas of these abnormal fibers the distribution of intramembraneous particles was similar to that of the internodal segments of normal axons with many more particles on the PF (internal) le...

journal_title：Neuroscience letters

authors： Bray GM,Cullen MJ,Aguayo AJ,Rasminsky M

更新日期：1979-07-01 00:00:00

abstract：:We compared the modulation of GABA (gamma-aminobutyric acid)-activated currents by benzodiazepines in recombinant GABAA receptors containing either one of two alpha subunits, alpha 1 or alpha 6. Lüddens et al. (Nature, 346 (1990) 648-651) have previously demonstrated that the alpha 6 subunit is part of a cerebellar re...

journal_title：Neuroscience letters

authors： Kleingoor C,Ewert M,von Blankenfeld G,Seeburg PH,Kettenmann H

更新日期：1991-09-16 00:00:00

abstract：:Emotions organize human and animal behaviour by automatically adjusting their actions at multiple physiological and behavioural scales. Recently, pattern recognition techniques have emerged as an important tool for quantifying the neural, physiological, and phenomenological organization of emotions in humans. Here we ...

journal_title：Neuroscience letters

authors： Nummenmaa L,Saarimäki H

更新日期：2019-02-06 00:00:00

abstract：:Neuronal cell cycle activation has been implicated in neurodegenerative diseases such as Alzheimer's disease, while the initiating mechanism of cell cycle activation remains to be determined. Interestingly, our previous studies have shown that cell cycle activation by c-Myc (Myc) leads to neuronal cell death which sug...

journal_title：Neuroscience letters

authors： Lee HP,Kudo W,Zhu X,Smith MA,Lee HG

更新日期：2011-11-14 00:00:00

abstract：:There is a growing interest for using quantitative EEG and LORETA current source density in clinical and research settings. Importantly, if these indices are to be employed in clinical settings then the reliability of these measures is of great concern. Neuroguide (Applied Neurosciences) is sophisticated software deve...

journal_title：Neuroscience letters

authors： Cannon RL,Baldwin DR,Shaw TL,Diloreto DJ,Phillips SM,Scruggs AM,Riehl TC

更新日期：2012-06-14 00:00:00

abstract：:Aluminum and zinc are two important trace elements in an organism. Although several studies have demonstrated their impacts on the intelligence, very little was known about their effects on the integrity of blood-brain barrier (BBB). To study the effects of aluminum and zinc on the permeability of BBB, different doses...

journal_title：Neuroscience letters

authors： Song Y,Xue Y,Liu X,Wang P,Liu L

更新日期：2008-11-07 00:00:00

abstract：:Activation of spinal astrocytes may contribute to neuropathic pain. Adjacent astrocytes can make direct communication through gap junctions formed by connexin 43 (Cx43) in the central nervous system. Yet, the role of spinal astroglial gap junctions in neuropathic pain is not fully understood. Since Cx43 is the connexi...

journal_title：Neuroscience letters

authors： Xu Q,Cheong YK,He SQ,Tiwari V,Liu J,Wang Y,Raja SN,Li J,Guan Y,Li W

更新日期：2014-04-30 00:00:00

abstract：:A major action of adenosine is the induction of profound behavioral inactivity. 6-(4-Nitrobenzyl)-thioinosine (NBI) and 6-(2-hydroxy-5-nitrobenzyl)-thioguanosine (NBG) have been shown to inhibit adenosine uptake. To investigate the possible synergism between exogenous ligand and reuptake inhibition, mice were treated ...

journal_title：Neuroscience letters

authors： Crawley JN,Patel J,Marangos PJ

更新日期：1983-04-11 00:00:00

abstract：BACKGROUND:The etiology of neurodegenerative disease remains unclear. Recently, SNP rs11868035, located in an intron of the sterol regulatory element binding factor (SREBF1) gene, was found to be associated with Parkinson's disease (PD) in a large European population in a genome-wide association study. To examine the p...

journal_title：Neuroscience letters

authors： Yuan X,Cao B,Wu Y,Chen Y,Wei Q,Ou R,Yang J,Chen X,Zhao B,Song W,Shang H

更新日期：2018-01-18 00:00:00

abstract：:Impaired energy metabolism plays an important role in neuronal cell death after brain ischemia, and apoptosis has been implicated in cell death induced by metabolic impairment. In the present study, metabolic impairment was induced by 3-nitropropionic acid (3-NP), an irreversible inhibitor of succinate dehydrogenase. ...

journal_title：Neuroscience letters

authors： Sugino T,Nozaki K,Tokime T,Hashimoto N,Kikuchi H

更新日期：1997-11-21 00:00:00

abstract：:The pathogens of Alzheimer's disease (AD) are still unclear, while accumulating evidences have indicated that both genetic and environmental factors are involved in the pathogenesis of AD. Recent studies suggest that AD is primarily a vascular disorder and copper (Cu) may play an important role in AD pathology. Howeve...

journal_title：Neuroscience letters

authors： Mao X,Ye J,Zhou S,Pi R,Dou J,Zang L,Chen X,Chao X,Li W,Liu M,Liu P

更新日期：2012-06-14 00:00:00

abstract：:We previously reported that Tyr-Leu (YL) exhibits potent anxiolytic-like activity comparable to diazepam in mice. In the current study, we revealed that aromatic amino acid-Leu, Phe-Leu and Trp-Leu (FL and WL, respectively), exhibited anxiolytic-like activity in the elevated plus-maze and open-field tests. FL and WL w...

journal_title：Neuroscience letters

authors： Mizushige T,Kanegawa N,Yamada A,Ota A,Kanamoto R,Ohinata K

更新日期：2013-05-24 00:00:00

abstract：:The antagonism of some benzodiazepine (Bz) actions by physostigmine was investigated in 4 Papio papio baboons. As a model of these actions, the myoclonus induced in this species by clonazepam i.m. administration was used. The baboon develops, 20-30 min after Bz i.m. injection, a non-epileptic myoclonus characterized b...

journal_title：Neuroscience letters

authors： Rektor I,Bryere P,Valin A,Silva-Barrat C,Naquet R,Menini C

更新日期：1984-11-23 00:00:00

abstract：:Neurotrophic factors may be used to improve the growth and repair of injured peripheral nerves. In this study we determined the effectiveness of recombinant human growth hormone on peripheral nerve injury in the Wistar rat. The ulnar nerve of the rat was sectioned and its proximal and distal ends were sutured to eithe...

journal_title：Neuroscience letters

authors： Saceda J,Isla A,Santiago S,Morales C,Odene C,Hernández B,Deniz K

更新日期：2011-10-24 00:00:00

abstract：:Several lines of evidence suggest that the amygdala is altered functionally in humans with temporal lobe epilepsy, but little is known about neuronal interactions in the amygdala of humans or animals with chronic epilepsy. Using extracellular and intracellular recordings in horizontal slices, we tested the hypothesis ...

journal_title：Neuroscience letters

authors： Smith BN,Dudek FE

更新日期：1997-01-24 00:00:00

abstract：:We reported here the functional characteristics of Na+ -dependent neutral amino acid transport system A in normal human astrocytes and its adaptive regulation, a process in which amino acid starvation induces the transport activity. Reverse transcription-PCR revealed that the system A transporter subtype, SNAT2/ATA2, ...

journal_title：Neuroscience letters

authors： Tanaka K,Yamamoto A,Fujita T

更新日期：2005-04-18 00:00:00

abstract：:The influence of insulin on the infarct volume due to middle cerebral artery (MCA) occlusion was investigated in rats. A small dose of insulin (1 unit/kg) was injected i.p. just after MCA occlusion. The infarct areas were measured by planimetry from brains perfused with 2,3,5-triphenyltetrazolium-chloride (TTC) 48 h a...

journal_title：Neuroscience letters

authors： Izumi Y,Pinard E,Roussel S,Seylaz J

更新日期：1992-09-14 00:00:00

abstract：:The motor activity of the rat bladder elicited by transmural electrical stimulation was abolished in the presence of 200 nM tetrodotoxin but not of 1 microM atropine plus 3.4 microM guanethidine. Tissue preincubation with 20 microM, alpha, beta-methylene ATP reduced but did not obliterate the electrically-induced moto...

journal_title：Neuroscience letters

authors： Acevedo CG,Lewin J,Contreras E,Huidobro-Toro JP

更新日期：1990-05-31 00:00:00

abstract：:Neurite outgrowth is elicited from whole explants or dissociated neurons of 8--10-day-old chick embryo sensory, dorsal root ganglia when cultured in the presence of a high speed supernatant fraction (105,000 g) from homogenates of chick or rat heart, liver or brain. The neurite promoting activity is not identical to m...

journal_title：Neuroscience letters

authors： Lindsay RM,Tarbit J

更新日期：1979-05-01 00:00:00

abstract：:Neuroblastoma cells differentiate in response to retinoic acid and cyclic AMP. We have examined the expression of retinoic acid receptors (RARs) in relation to neuroblastoma differentiation and show that short term exposure of SK N SH, SH SY 5Y AND GI LI N cells to physiological concentrations of retinoic acid results...

journal_title：Neuroscience letters

authors： Lovat PE,Pearson AD,Malcolm A,Redfern CP

更新日期：1993-11-12 00:00:00

abstract：:The accumulation of choline acetyltransferase (CAT) proximal to and nerve growth factor (NGF) distal to the intraneural site of tetrodotoxin (TTX) or batrachotoxin (BTX) injection in vivo was used to monitor orthograde and retrograde axonal transport. Orthograde axonal transport was blocked by BTX for up to 7-10 days ...

journal_title：Neuroscience letters

authors： Boegman RJ,Riopelle RJ

更新日期：1980-06-01 00:00:00

abstract：:Jet propulsion fuel-8 (JP-8) is the predominant fuel for military land vehicles and aircraft used in the US and NATO. Occupational exposure to jet fuel in military personnel has raised concern for the health risk associated with such exposure in the Department of Defense. Clinical studies of humans chronically exposed...

journal_title：Neuroscience letters

authors： Lin B,Ritchie GD,Rossi J 3rd,Pancrazio JJ

更新日期：2004-06-17 00:00:00

abstract：:Prior work demonstrated that immune surveillance of the brain occurs primarily through the blood-cerebrospinal (CSF) fluid barrier rather than the blood-brain barrier endothelium. Recently, we identified epithelial V-like antigen (EVA), an immunoglobulin-like adhesion molecule, as a regulator of blood-CSF barrier inte...

journal_title：Neuroscience letters

authors： Wojcik E,Carrithers LM,Carrithers MD

更新日期：2011-05-16 00:00:00

abstract：:Although synaptically released, vesicular Zn(2+) has been proposed to play a neuromodulatory or neuronal signaling role at the mossy fiber-CA3 synapse, Zn(2+) release remains controversial, especially when detected using fluorescent imaging. In the present study, we investigated synaptically released Zn(2+) at the mos...

journal_title：Neuroscience letters

authors： Bastian C,Li YV

更新日期：2007-05-29 00:00:00

abstract：:The cellular localization of Thy-1 in the chick retina was investigated by selectively destroying certain populations of neurons with toxins. In control retinae four weeks after intravitreal injection of vehicle, there was strong immunoreactivity for Thy-1 in the nerve fibre layer, ganglion cell layer and inner plexif...

journal_title：Neuroscience letters

authors： Sheppard AM,Konopka M,Robinson SR,Morgan IG,Jeffrey PL

更新日期：1991-02-11 00:00:00

abstract：:The high-affinity of [3H]gamma-aminobutyric acid (GABA) to GABAA receptors and [3H]baclofen to GABAB receptors were studied in the cerebellum of pyridoxine-deficient rats and compared to pyridoxine-supplemented controls. There was a significant increase in the maximal binding (Bmax) of both GABAA and GABAB receptors w...

journal_title：Neuroscience letters

authors： Paulose CS,Dakshinamurti K

更新日期：1984-08-10 00:00:00

abstract：:To examine postural stability of the head, slow, undetectable rotations of small amplitude were imposed about a vertical axis while human subjects maintained a stationary body. Six normal subjects were used. The rotations were imposed through an elastic linkage, and lasted 4 s. The amplitude of head rotation was small...

journal_title：Neuroscience letters

authors： Chan R,Rogers DK,McCloskey DI

更新日期：1996-08-23 00:00:00

abstract：:Histone modifications, such as lysine methylation, acetylation and ubiquitination, are epigenetic tags that shape the chromatin landscape and regulate transcription required for synaptic plasticity and memory. Here, we show that transcription-promoting histone H3 trimethylated at lysine 4 (H3K4me3), histone H3 acetyla...

journal_title：Neuroscience letters

authors： Bach SV,Tacon PR,Morgan JW,Hegde AN

更新日期：2015-03-30 00:00:00