Node-like areas of intramembraneous particles in the unensheathed axons of dystrophic mice.

abstract：:Several lines of evidence suggest that the amygdala is altered functionally in humans with temporal lobe epilepsy, but little is known about neuronal interactions in the amygdala of humans or animals with chronic epilepsy. Using extracellular and intracellular recordings in horizontal slices, we tested the hypothesis ...

journal_title：Neuroscience letters

authors： Smith BN,Dudek FE

更新日期：1997-01-24 00:00:00

abstract：:Mesial temporal lobe epilepsy (MTLE) is a common type of intractable epilepsy characterized by astroglial gliosis. The S100B was viewed as an astrocyte marker and experimental studies indicated that S100B might be involved in the pathophysiology of temporal lobe epilepsy. In this study, we measured plasma S100B levels...

journal_title：Neuroscience letters

authors： Lu C,Li J,Sun W,Feng L,Li L,Liu A,Li J,Mao W,Wei H,Gao L,Zhang X,Huang Z,Meng X,Wang Y

更新日期：2010-10-29 00:00:00

abstract：:Glutamatergic system, the main stimulating system of the brain, plays an important role in the pathogenesis of schizophrenia. Hippocampus, a structure crucial for memory and cognitive functions and rich in glutamatergic neurons, is a natural object of interest in studies on psychoses. Sarcosine, a glycine transporter ...

journal_title：Neuroscience letters

authors： Strzelecki D,Podgórski M,Kałużyńska O,Gawlik-Kotelnicka O,Stefańczyk L,Kotlicka-Antczak M,Gmitrowicz A,Grzelak P

更新日期：2015-10-08 00:00:00

abstract：:Parkinson's disease (PD) is a progressive age-related debilitating motor disorder and the second most common neurodegenerative disease after Alzheimer's disease. In this study, we aimed to investigate the expression of 24 candidate miRNAs in PD and to assess their diagnostic value in patients with PD. We collected ser...

journal_title：Neuroscience letters

authors： Cao XY,Lu JM,Zhao ZQ,Li MC,Lu T,An XS,Xue LJ

更新日期：2017-03-22 00:00:00

abstract：:Neuron number and volume of the recently described vasopressin and oxytocin containing nucleus (VON) in the pig hypothalamus have been studied into adulthood. Following a 2.5-fold increase in both sexes around puberty, both neuron number and volume of the VON continued to increase in the female pig between 1 and 2.5 y...

journal_title：Neuroscience letters

authors： van Eerdenburg FJ,Swaab DF

更新日期：1991-10-28 00:00:00

abstract：:Transcranial pulsed current stimulation (tPCS) and transcranial direct current stimulation (tDCS) are two noninvasive neuromodulatory brain stimulation techniques whose effects on human brain and behavior have been studied individually. In the present study we aimed to quantify the effects of tDCS and tPCS, individual...

journal_title：Neuroscience letters

authors： Thibaut A,Russo C,Morales-Quezada L,Hurtado-Puerto A,Deitos A,Freedman S,Carvalho S,Fregni F

更新日期：2017-01-10 00:00:00

abstract：:Insulin secretion and glucose homeostasis is implicated through serotonergic function. Pyridoxine is involved in decarboxylation step in synthesis of serotonin. The present study was carried out to find the role of insulin in combination with pyridoxine on the concentrations of 5-HT and 5-HIAA, 5-HT receptor binding, ...

journal_title：Neuroscience letters

authors： Abraham PM,Anju TR,Jayanarayanan S,Paulose CS

更新日期：2010-10-08 00:00:00

abstract：:The adenosine triphosphate (ATP)-dependent sodium/potassium pump extrudes intracellular sodium in exchange for extracellular potassium. Low ATP causes pump dysfunction increasing both intracellular sodium and water thereby enhancing metabolite mobility. This should be detectable by proton magnetic resonance spectrosco...

journal_title：Neuroscience letters

authors： Cady EB,Lorek A,Penrice J,Wylezinska M,Cooper CE,Brown GC,Owen-Reece H,Kirkbride V,Wyatt JS,Osmund E

更新日期：1994-12-05 00:00:00

abstract：:CART peptides are important neurotransmitters, but little is known about their receptors or signaling pathways in cells. In this study we describe the effects of CART 55-102 on the stimulation of extracellular signal-related kinase (ERK) in a pituitary-derived cell line. CART 55-102 treatment resulted in markedly enha...

journal_title：Neuroscience letters

authors： Lakatos A,Prinster S,Vicentic A,Hall RA,Kuhar MJ

更新日期：2005-08-12 00:00:00

abstract：:Neuronal recording and neuroimaging studies have shown that the primary motor area (M1) not only participates in motor execution, but is also engaged during movement preparation. The purpose of the present study was to map the distribution of the preparation- and execution-related activity within the contralateral M1 ...

journal_title：Neuroscience letters

authors： Zang Y,Jia F,Weng X,Li E,Cui S,Wang Y,Hazeltine E,Ivry R

更新日期：2003-02-06 00:00:00

abstract：:Neuroinflammation is a critical component in the progression of several neurological and neurodegenerative diseases and cyclooxygenases (COX)-1 and -2 are key regulators of innate immune responses. We recently demonstrated that COX-1 deletion attenuates, whereas COX-2 deletion enhances, the neuroinflammatory response,...

journal_title：Neuroscience letters

authors： Aid S,Parikh N,Palumbo S,Bosetti F

更新日期：2010-07-12 00:00:00

abstract：:Effects of fourth cerebroventricular injection of thyrotropin-releasing hormone (TRH) on respiration were studied in vagotomized rabbits. Phrenic neural activity was recorded and integrated. TRH (1.0 microgram) injection facilitated phrenic neural activity and increased respiratory rate. Peak phrenic nerve activity in...

journal_title：Neuroscience letters

authors： Homma I,Oouchi M,Ichikawa S

更新日期：1984-02-24 00:00:00

abstract：:The action of glycine (Gly) on rat cortical neurons was studied. Gly, iontophoretically applied, hyperpolarized the membrane potential, blocked the firing rate and decreased the amplitude of EPSP-IPSP sequences. Generally the membrane resistance during the aminoacid ejection decreased. The role of Gly in the rat corti...

journal_title：Neuroscience letters

authors： Bernardi G,Cherubini E,Marciani MG,Stanzione P

更新日期：1979-05-01 00:00:00

abstract：:Peroxisomal activities were examined in liver and brain of lactating neonatal rats of mothers maintained on ciprofibrate, a peroxisomal proliferator. The activities of DHAP-acyltransferase, alkyl-DHAP synthetase and the beta-oxidation of palmitic and lignoceric acids increased in brain by 3.9, 2.2, 4.3 and 3.2 fold an...

journal_title：Neuroscience letters

authors： Singh I,Lazo O

更新日期：1992-04-27 00:00:00

abstract：:Previous studies using 2-deoxyglucose (2-DG) autoradiography have demonstrated that the suprachiasmatic nucleus (SCN) of the hypothalamus, a putative neural circadian pacemaker, displays circadian rhythmicity in its metabolic activity. In the present study, we show that distinct circadian variations in 2-DG uptake occ...

journal_title：Neuroscience letters

authors： Rosenwasser AM,Trubowitsch G,Adler NT

更新日期：1985-07-31 00:00:00

abstract：:This study aimed to determine whether neuropathic pain is associated with a plasticity change in the number of synapses in the spinal dorsal horn. 12 normal adult SD rats were randomly divided into two groups: 7 animals were subjected to unilateral loose ligation (to induce chronic constriction injury) of the sciatic ...

journal_title：Neuroscience letters

authors： Peng B,Lin JY,Shang Y,Yang ZW,Wang YP

更新日期：2010-12-03 00:00:00

abstract：:Recent findings indicated that the excitotoxicity of glutamate analogues was prevented in the mammalian nervous system by N-methyl-D-aspartate (NMDA) antagonists. The neurodegenerative effects of kainic acid, and the putative protection of MK-801 and 6,7-dinitroquinoxaline-2,3-dione (DNQX), were investigated by morpho...

journal_title：Neuroscience letters

authors： Villani L,Carraro S,Guarnieri T

更新日期：1995-06-09 00:00:00

abstract：:Gap junctions between neurons contribute to synchronous neuronal firing and may play a role in the pathophysiology of epilepsy. We examined the expression of a number of gap junction subunits, including the neuronal gap junction forming protein connexin36 (Cx36), in the hippocampus at various time points following an ...

journal_title：Neuroscience letters

authors： McCracken CB,Roberts DC

更新日期：2006-09-11 00:00:00

abstract：:The effect of systemic morphine (5 mg/kg) on the C-fibre evoked activity in the dorsal horn of decerebrate spinalized rats has been investigated. Activity in units recorded from lamina 5 was inhibited in a naloxone-reversible fashion by morphine. However, morphine produced variable changes in the C-evoked activity of ...

journal_title：Neuroscience letters

authors： Woolf CJ,Fitzgerald M

更新日期：1981-08-07 00:00:00

abstract：:Behavioural sensitization to a single morphine exposure has been considered to be a long-term form of behavioural plasticity associated with opioid addiction. Accumulated evidence has shown that histone modification plays a key role in behavioural plasticity. Therefore, this study was designed to investigate whether t...

journal_title：Neuroscience letters

authors： Jing L,Luo J,Zhang M,Qin WJ,Li YL,Liu Q,Wang YT,Lawrence AJ,Liang JH

更新日期：2011-04-25 00:00:00

abstract：:Intra-arterial (i.a.) injection of Indian red scorpion (Mesobuthus tamulus; BT) venom produces cardiorespiratory changes by involving perivascular receptors. The afferents involved in mediating these reflex responses are not known. The present investigation was conducted to examine the afferents mediating the vasosens...

journal_title：Neuroscience letters

authors： Singh SK,Deshpande SB

更新日期：2008-06-13 00:00:00

abstract：:Research indicates that threat-induced changes in standing balance are associated with shifts in attention focus. This study investigated whether distracting attention modifies threat-induced changes in standing balance. Twenty-five healthy young adults stood without (No Threat) and with (Threat) the possibility of re...

journal_title：Neuroscience letters

authors： Johnson KJ,Watson AM,Tokuno CD,Carpenter MG,Adkin AL

更新日期：2020-01-18 00:00:00

abstract：:Daily administration of clonidine for 5 weeks (approx. 300 micrograms/kg/day, p.o.) produced significant decreases in blood pressure and renal sympathetic efferent activity in spontaneously hypertensive rats (SHR). After cessation of clonidine administration, blood pressure and sympathetic nerve activity recovered rap...

journal_title：Neuroscience letters

authors： Yomaida I,Murao M,Togashi H,Shimamura K,Koike Y,Monma Y,Saito HA

更新日期：1979-12-01 00:00:00

abstract：:Nerve guide implants approved for human application in the peripheral nervous system generally fail to bridge lesion gaps longer than 2 cm and cannot match the clinical performance of autologous nerve transplants. Since current synthetic implants are simply hollow tubes, we aim to recreate the native microarchitecture...

journal_title：Neuroscience letters

authors： Nichterwitz S,Hoffmann N,Hajosch R,Oberhoffner S,Schlosshauer B

更新日期：2010-10-29 00:00:00

abstract：:One of the clinical characteristics of psychogenic tremors (PT) is the disruption or transient cessation of tremor with distractive manoeuvres, including those involving the performance of voluntary movements with the contralateral hand. Seven patients with PT, 11 patients with Parkinson's disease (PD), 10 patients wi...

journal_title：Neuroscience letters

authors： Kumru H,Valls-Solé J,Valldeoriola F,Marti MJ,Sanegre MT,Tolosa E

更新日期：2004-11-11 00:00:00

abstract：:Little is known about the metabolic process of tau and tau-derived substances. Alz-50- and tau 2-immunoreactivities in intracellular granules of neurons were observed in regions surrounding infarcted foci in the human cerebral cortex. Ultrastructurally, these granules in the fresh infarcted region exhibited primary ly...

journal_title：Neuroscience letters

authors： Ikeda K,Akiyama H,Arai T,Kondo H,Haga C,Tsuchiya K,Yamada S,Murayama S,Hori A

更新日期：2000-04-28 00:00:00

abstract：:Intrastriatal injections of kainic acid in rat brain, which destroyed striatal nerve cell bodies and their axons projecting to the substantia nigra (s. nigra) decreased the rate of breakdown of exogenuously added substance P by washed slice preparations of s. nigra. Injection of 6-hydroxydopamine (6-OHDA) into the s. ...

journal_title：Neuroscience letters

authors： Quik M,Emson PC

更新日期：1979-12-01 00:00:00

abstract：:Loss of ganglion cells is a common and irreversible complication of hair cell loss in the cochlea. Gene transfer could potentially be used to prevent this neuronal degeneration and other pathologies in the cochlea. Human adenoviruses should provide a feasible gene transfer vehicle for transducing the quiescent cochlea...

journal_title：Neuroscience letters

authors： Raphael Y,Frisancho JC,Roessler BJ

更新日期：1996-03-29 00:00:00

abstract：:The contribution of angiotensin II (Ang II) to the pathophysiology of hypertension is established based on facts that high levels of circulating Ang II increase vasoconstriction of peripheral arteries causing a rise in blood pressure (BP). In addition, circulating Ang II has various effects on the central nervous syst...

journal_title：Neuroscience letters

authors： Issa AT,Miyata K,Heng V,Mitchell KD,Derbenev AV

更新日期：2012-06-21 00:00:00

abstract：:In experiments using a synaptosomal preparation from the striatum and nucleus accumbens, somatostatin caused a dose-dependent increase in dopamine synthesis. This increase was additive with that produced by 8-BrcAMP but not with that produced by the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate (TPA), and was bl...

journal_title：Neuroscience letters

authors： Chowdhury M,Steardo L,Fillenz M

更新日期：1987-11-23 00:00:00