Increasing neuron numbers in the vasopressin and oxytocin containing nucleus of the adult female pig hypothalamus.

abstract：:The MgATP-dependent priming step of exocytosis has been suggested to be regulated negatively by GTP-binding protein G0 in permeabilized adrenal chromaffin cells. We have reported that synaptosomal-associated protein of 25 kDa (SNAP-25) and vesicle-associated membrane protein 2 (VAMP-2) form a complex in chromaffin cel...

journal_title：Neuroscience letters

authors： Misonou H,Ohara-Imaizumi M,Kumakura K

更新日期：1997-09-05 00:00:00

abstract：:Complement is implicated in the pathogenesis of inflammatory disorders of the central nervous system (CNS), like multiple sclerosis, Alzheimer's disease, and trauma. The anaphylatoxins C3a and C5a are thought to be the major contributors to complement-mediated inflammation in the CNS, likely mediating their effects vi...

journal_title：Neuroscience letters

authors： Boos L,Szalai AJ,Barnum SR

更新日期：2005-10-21 00:00:00

abstract：:Pain is a complex and subjective experience that involves not only the transduction of noxious stimuli by nociceptive fibers, but also the cognitive and emotional processing by the brain. Previous studies on the transmission of nociception suggest that the activation of mesolimbic dopamine (DA) system plays an importa...

journal_title：Neuroscience letters

authors： Zhu J,Chen Y,Lai J,Dang Y,Yan C,Xu M,Chen T

更新日期：2010-06-25 00:00:00

abstract：:The role of the serotonergic system in regulating the expression of estrogen receptor (ER) α in the hypothalamus was investigated in ovariectomized rats by injecting a serotonin synthesis inhibitor, parachlorophenylalanine (PCPA), or by destroying the dorsal raphe nucleus (DR). The number of ERα-immunoreactive (ir) ce...

journal_title：Neuroscience letters

authors： Ito H,Shimogawa Y,Kohagura D,Moriizumi T,Yamanouchi K

更新日期：2014-11-07 00:00:00

abstract：:Around 200,000 veterans (up to 32% of those deployed) of the 1991 Gulf War (GW) suffer from GW illness (GWI), which is characterized by multiple deficits in cognitive, affective, sensory and nociception domains. In this study we employed resting state fMRI (rsfMRI) to map impairments in brain function in GWI with adva...

journal_title：Neuroscience letters

authors： Gopinath KS,Sakoglu U,Crosson BA,Haley RW

更新日期：2019-05-14 00:00:00

abstract：:Many studies have shown that acupuncture can contribute to the biochemical balance in the central nervous system and maintenance or recovery of homeostasis. It is well known that chronic administration of ethanol may produce depletion or sensitization of extracellular dopamine levels in the nucleus accumbens. The pres...

journal_title：Neuroscience letters

authors： Zhao RJ,Yoon SS,Lee BH,Kwon YK,Kim KJ,Shim I,Choi KH,Kim MR,Golden GT,Yang CH

更新日期：2006-02-27 00:00:00

abstract：:Repeated stimulation can lead to a decrement in the amplitude of a response, or its disappearance. This is known as habituation. Responses recorded in the reticular formation of the brain to peripherally applied stimuli tend to habituate. Decerebration considerably reduces the occurrence of this habituation and naloxo...

journal_title：Neuroscience letters

authors： Boxer MI

更新日期：1983-09-19 00:00:00

abstract：:The dentate gyrus of the hippocampus is one of few regions in the adult mammalian brain characterized by ongoing neurogenesis. It has been demonstrated that Noggin antagonizes bone morphogenetic protein-4 (BMP4) to create a niche for subventricular zone neurogenesis. We previously demonstrated that Noggin and BMP4 sho...

journal_title：Neuroscience letters

authors： Fan XT,Xu HW,Cai WQ,Yang H,Liu S

更新日期：2004-08-05 00:00:00

abstract：:The blood-brain barrier (BBB) maintains the homeostasis between the central nervous system and the blood circulation. One of the main efflux transporter proteins at the BBB is P-glycoprotein (P-gP) also known as ABCB1 or MDR1. Due to the important role of P-gP for the transport barrier function of the BBB, the presenc...

journal_title：Neuroscience letters

authors： Neuhaus W,Stessl M,Strizsik E,Bennani-Baiti B,Wirth M,Toegel S,Modha M,Winkler J,Gabor F,Viernstein H,Noe CR

更新日期：2010-01-22 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by amyloid plaques, neuritic degenerations, disturbed glutamatergic neurotransmission and a peculiar inflammatory response. Diffuse plaques develop into neuritic plaques when neurites undergo degeneration in the plaque area. Hyperphosphorylation of tau proteins is a major step...

journal_title：Neuroscience letters

authors： Hüll M,Eistetter J,Fiebich BL,Bauer J

更新日期：1999-02-12 00:00:00

abstract：:A valinomycin-based membrane phase for microelectrodes with relatively low electrical membrane resistances is described. Microelectrodes with tip diameters of about 1 micron exhibit resistances of about 10(10) omega. Extremely high K+ selectivities are obtained, e.g. a rejection of Na+ by a factor of 5000 and of acety...

journal_title：Neuroscience letters

authors： Ammann D,Chao PS,Simon W

更新日期：1987-02-24 00:00:00

abstract：:8-Hydroxy-2-[di-n-propylamino]-tetralin) (8-OH-DPAT), a 5-HT1A/7 receptor agonist, has a chronobiological effect on the circadian system. To identify how the 8-OH-DPAT exerts this effect, we specifically destroyed the serotonergic (5-HT) fibres connecting the median raphe nuclei (RN) to the suprachiasmatic nuclei (SCN...

journal_title：Neuroscience letters

authors： Schuhler S,Saboureau M,Pitrosky B,Pévet P

更新日期：1998-10-30 00:00:00

abstract：:Despite extensive data addressing the regulation of the hypothalamo-pituitary-adrenal (HPA) axis in vertebrates, the neuroendocrine regulation of stress in birds remains incomplete. The paraventricular nucleus (PVN) contains the key neuropeptides, corticotropin releasing hormone (CRH) and arginine vasotocin (AVT), con...

journal_title：Neuroscience letters

authors： Nagarajan G,Kang SW,Kuenzel WJ

更新日期：2017-03-06 00:00:00

abstract：:Oxidative damage induced-mitochondrial dysfunction and apoptosis has been widely studied in spinal cord injury (SCI). Lycopene, a polyunsaturated hydrocarbon, has the highest antioxidant capacity compared to the other carotenoids. However, the role of lycopene in SCI is unknown. In the present study, we evaluated the ...

journal_title：Neuroscience letters

authors： Hu W,Wang H,Liu Z,Liu Y,Wang R,Luo X,Huang Y

更新日期：2017-03-06 00:00:00

abstract：:Alterations of Ca2+ homeostasis have been reported for both fibroblasts and T-lymphocytes of patients with Alzheimer's disease (AD). Considering the importance of K+ conductances for the cellular Ca2+ regulation and the recently reported absence of a K+ channel in Alzheimer fibroblasts, we investigated K+ currents in ...

journal_title：Neuroscience letters

authors： Cohen CD,Vollmayr B,Aldenhoff JB

更新日期：1996-01-05 00:00:00

abstract：:This study investigated the neuroprotective effects of COG1410, an apoliporotein E (apoE)-derived mimic peptide, against early brain injury (EBI) after subarachnoid hemorrhage (SAH). SAH was induced in C57BL/6J mice (n=68) by endovascular perforation. Mice received intravenous injection of COG1410 (2mg/kg) or equal vo...

journal_title：Neuroscience letters

authors： Wu Y,Pang J,Peng J,Cao F,Vitek MP,Li F,Jiang Y,Sun X

更新日期：2016-08-03 00:00:00

abstract：:It is generally assumed that the majority of substance P (SP)-containing afferents are also immunoreactive for calcitonin gene-related peptide (CGRP). In order to determine whether this is also the case in articular afferents where the contents of these peptides are low, we carried out a double labeling study using Fa...

journal_title：Neuroscience letters

authors： Tamura R,Hanesch U,Schmidt RF,Kumazawa T,Mizumura K

更新日期：1998-09-18 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH) metabolism in NIH:N mouse cerebral cortex and spinal cord was studied with high pressure liquid chromatography. Degradation of added TRH was significantly (P less than 0.001) slower in the spinal cord (2.19 +/- 0.46%/min) than in the cerebral cortex (7.54 +/- 0.31%/min). Bacitracin,...

journal_title：Neuroscience letters

authors： Schwartz TM,Turner JG,Brooks BR

更新日期：1986-11-11 00:00:00

abstract：:Amyloid beta (Aβ) is the main component of plaques, the central neuropathological hallmark in Alzheimer's disease (AD). Aβ is derived from the amyloid precursor protein (APP) by β- and γ-secretase-mediated cleavages. A large number of Aβ peptides are found in cerebrospinal fluid and these peptides are produced in spec...

journal_title：Neuroscience letters

authors： Pannee J,Törnqvist U,Westerlund A,Ingelsson M,Lannfelt L,Brinkmalm G,Persson R,Gobom J,Svensson J,Johansson P,Zetterberg H,Blennow K,Portelius E

更新日期：2014-06-24 00:00:00

abstract：:The pharmacological properties of presynaptic calcium (Ca) channels on rat hippocampal mossy fiber synaptosomes were characterized by determining the inhibitory potencies for various classes of Ca antagonists on depolarization-induced Ca mobilization and the release of dynorphin A(1-8)-like immunoreactivity (Dyn-LI). ...

journal_title：Neuroscience letters

authors： Terrian DM,Damron DS,Dorman RV,Gannon RL

更新日期：1989-12-04 00:00:00

abstract：:Following various types of wounds and subsequent denervation, the reinnervation of the rabbit corneal epithelium was found to occur in two distinct phases that overlapped in time. In the first phase large numbers of collateral sprouts originated from the unmyelinated plexus at various distances proximal to the site of...

journal_title：Neuroscience letters

authors： Beuerman RW,Rózsa AJ

更新日期：1984-01-27 00:00:00

abstract：:Previous studies have observed increased tachykinin NK(1) receptor immunoreactivity (NK(1)-IR) in the prefrontal cortex in subjects with schizophrenia. Since the subjects were medicated the possibility of a treatment effect could not be excluded. Thus, the present study was undertaken to determine the effect of chroni...

journal_title：Neuroscience letters

authors： Tooney PA,Anderson WB,Lynch-Frame A,Chahl LA

更新日期：2005-07-22 00:00:00

abstract：:A cDNA clone encoding a novel protein (Cer-1) was isolated from a mouse cerebellar cDNA library. The deduced amino acid sequence of Cer-1 is not homologous to other sequences in the protein sequence data base. RNA blot analysis suggests that expression of Cer-1 RNA occurs selectively in the adult cerebellum and in pur...

journal_title：Neuroscience letters

authors： Bulleit RF,Lin X,Jeppi JV

更新日期：1996-05-10 00:00:00

abstract：:In animal models endogenous cannabinoids have an inhibitory effect on trigeminovascular activation through the cannabinoid receptor 1 (CB1), although there is no evidence of the potential role of CB1 in human migraine. In this study we applied single marker association and haplotypic trend regression analysis to inves...

journal_title：Neuroscience letters

authors： Juhasz G,Lazary J,Chase D,Pegg E,Downey D,Toth ZG,Stones K,Platt H,Mekli K,Payton A,Anderson IM,Deakin JF,Bagdy G

更新日期：2009-09-18 00:00:00

abstract：:Freshwater clams are a popular health food in Asia and are traditionally used to prevent hepatic inflammation. Freshwater clam extract (FCE) inhibits inflammatory responses in activated macrophages by reducing the activation of mitogen-activated protein kinase and nuclear factor kappa-light-chain-enhancer of activated...

journal_title：Neuroscience letters

authors： Hsieh CC,Lin MS,Hua KF,Chen WJ,Lin CC

更新日期：2017-03-06 00:00:00

abstract：:Event-related brain potentials were recorded from healthy human subjects while they attended to one of two auditory stimulus channels (defined by location, left and right of a fixation point, and pitch) in order to detect rare target events. The distracting properties of periodic noise (vs. continuous noise, experimen...

journal_title：Neuroscience letters

authors： Nager W,Rosenthal O,Bohrer I,Teder-Sälejärvi WA,Münte TF

更新日期：2001-01-05 00:00:00

abstract：:This study analysed the equilibrium strategies and EMG activity during postural equilibrium in four different unstable surfaces. Thirteen team sport males were tested on a FLAT surface and on three different wobble boards (JAKOBS(®) with easy multidirectional displacements, FREEMAN with strong multidirectional displac...

journal_title：Neuroscience letters

authors： Cimadoro G,Paizis C,Alberti G,Babault N

更新日期：2013-08-26 00:00:00

abstract：:Elongation factor-2 kinase (eEF-2K) is a Ca(2+)/calmodulin-dependent protein kinase that is highly specific for eukaryotic elongation factor-2. In the present study, we examined the developmental expression of eEF-2K messenger RNA (mRNA) in the mouse brain. At E13, the expression of eEF-2K mRNA is already evident in b...

journal_title：Neuroscience letters

authors： Sakagami H,Nishimura H,Saito R,Kondo H

更新日期：2002-09-13 00:00:00

abstract：:Expiratory only resistive loaded breathing (RL) reduces high energy electromyogram (EMG) power (EH) during an isometric contraction of a leg extensor muscle, but not an arm flexor. An interaction between afferent activity during expiratory RL and inspiratory non-loaded phases of breathing, which the contraction spanne...

journal_title：Neuroscience letters

authors： Turner D,Sumners P,Jackson S

更新日期：2000-12-15 00:00:00

abstract：:The physiological role of mGluR1-induced inward current in a Purkinje neuron was studied in a cerebellar slice preparation. In a voltage-clamp condition, application of a mGluR1 agonist (RS)-3,5-dihydroxyphenylglycine (DHPG) induced both the transient and sustained phases of inward currents, which were blocked by simu...

journal_title：Neuroscience letters

authors： Yamakawa Y,Hirano T

更新日期：1999-12-24 00:00:00