Presynaptic localization of substance P degradative enzymes(s) in rat substantia nigra.

abstract：:It was established that stimulation of the lateral hypothalamus (LH) can induce antinociception. Previous studies showed a role for the ventral tegmental area (VTA) and nucleus accumbens (NAc) in antinociception induced by LH stimulation through the orexinergic system. In this study, we tried to assess the involvement...

journal_title：Neuroscience letters

authors： Moradi M,Fatahi Z,Haghparast A

更新日期：2015-07-10 00:00:00

abstract：:Galectin-3 is a β-galactosidase-binding lectin which is important in cell proliferation and apoptotic regulation. Encephalomyocarditis virus (EMCV), which includes the Enterovirus genus, can cause not only acute myocarditis but also neuronal degeneration of central nervous system in various animals including mice. The...

journal_title：Neuroscience letters

authors： Kobayashi K,Niwa M,Hoshi M,Saito K,Hisamatsu K,Hatano Y,Tomita H,Miyazaki T,Hara A

更新日期：2015-04-10 00:00:00

abstract：:Cholinergic projections originating in the basal forebrain (BF) play important roles in the heterosynaptic facilitation of synaptic strength in various sensory cortices, including the primary visual cortex (V1). Here, using urethane-anesthetized rats, we find that pairing burst stimulation of the BF with single pulse ...

journal_title：Neuroscience letters

authors： Gagolewicz PJ,Dringenberg HC

更新日期：2009-10-02 00:00:00

abstract：:Throughout life, new neurons are continuously generated from subventricular zone and added to the olfactory bulb (OB). Because a subset of mature OB neurons undergoes spontaneous cell death, adult OB neurogenesis serves for the replacement of this cell loss. Spontaneous cell turnover should alter the neuronal circuits...

journal_title：Neuroscience letters

authors： Kim WR,Sun W

更新日期：2013-08-26 00:00:00

abstract：:The magnetic cell sorter (MACS) technique was applied to isolate retinal ganglion cells (RGCs) for culture. RGCs were labeled retrogradely with 1.1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (Dil). Subsequently retinal cell suspensions were incubated with biotinylated anti-rat Thy-1 antibody and MA...

journal_title：Neuroscience letters

authors： Shoge K,Mishima HK,Mukai S,Shinya M,Ishihara K,Kanno M,Sasa M

更新日期：1999-01-08 00:00:00

abstract：:Astrocytes are effectively involved in the pathophysiological processes in the central nervous system (CNS) and may contribute to or protect against development of inflammatory and degenerative diseases. Sildenafil is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor, which induces cyclic GMP accumulation. ...

journal_title：Neuroscience letters

authors： de Santana Nunes AK,Rapôso C,Björklund U,da Cruz-Höfling MA,Peixoto CA,Hansson E

更新日期：2016-09-06 00:00:00

abstract：:Fe65 is a brain enriched multi domain adaptor protein involved in diverse cellular functions. One of its binding partners is the amyloid-β (Aβ) precursor protein (APP), which after sequential proteolytic processing by secretases gives rise to the Alzheimer's Aβ peptide. Fe65 binds to the APP intracellular domain (AICD...

journal_title：Neuroscience letters

authors： Koistinen NA,Bacanu S,Iverfeldt K

更新日期：2016-02-02 00:00:00

abstract：:To identify the BOLD effects related to olfaction in humans, we recorded functional magnetic resonance imaging (fMRI) scans in response intravenously instilled thiamine propyl disulfide (TPD) and thiamine tetrahydrofurfuryl disulfide monohydrochloride (TTFD). TPD and TTFD evoked a strong and weak odor sensation, respe...

journal_title：Neuroscience letters

authors： Miyanari A,Kaneoke Y,Noguchi Y,Honda M,Sadato N,Sagara Y,Kakigi R

更新日期：2007-08-09 00:00:00

abstract：:Exposure to morphine during pregnancy produced long-term effects in offspring behaviors. Recent studies have shown that voluntary exercise decreases the severity of anxiety behaviors in both morphine-dependent and withdrawn rats. Thus, the aims of the present study were to examine whether maternal exercise decreases p...

journal_title：Neuroscience letters

authors： Haydari S,Miladi-Gorji H,Mokhtari A,Safari M

更新日期：2014-08-22 00:00:00

abstract：:Attention-deficit/hyperactivity disorder (ADHD) is highly prevalent in children and adolescents and both environmental and genetic factors play major roles. Polyunsaturated fatty acids (PUFAs) are postulated to contribute to the development of the infant brain and an imbalance in these may increase the risk of ADHD. I...

journal_title：Neuroscience letters

authors： Bartl J,Walitza S,Grünblatt E

更新日期：2014-01-24 00:00:00

abstract：:Presenilin 1 mutations are the major cause of autosomal dominant Alzheimer's disease. Here we present evidence that pathogenic mutations in putative transmembrane domains 1, 2, 3, 4 and 6 align along helical faces, thus supporting the view that these are indeed transmembrane domains, and suggesting that disruption of ...

journal_title：Neuroscience letters

authors： Hardy J,Crook R

更新日期：2001-06-29 00:00:00

abstract：:This study reports the solubilization of the rat synaptic vesicle protein SV2A, the brain binding site for the antiepileptic drug levetiracetam (LEV), and its characterization. N-dodecyl-beta-D-maltoside (DDM) was the best detergent at achieving a high percentage of SV2A solubilization and at maintaining the binding c...

journal_title：Neuroscience letters

authors： Lambeng N,Grossmann M,Chatelain P,Fuks B

更新日期：2006-05-01 00:00:00

abstract：:Chronic activation of protein kinase C (PKC) has been implicated in regulation of Ca2+ entry responsible for normal development of transmitter properties in cultured sympathetic neurons. The idea that PKC alters the expression of Ca2+ channels was tested using phorbol 12,13-dibutyrate (PDB) which activates PKC and als...

journal_title：Neuroscience letters

authors： Przywara DA,Zhong H,Kulkarni JS,Anderson GF,Wakade AR

更新日期：1997-06-27 00:00:00

abstract：:The size and somatotopic distribution of corneal afferent neurons in the guinea pig trigeminal ganglion were determined using a retrograde axonal tracing technique. Wheat germ agglutinin-horseradish peroxidase (WGA-HRP) was applied to the central cornea of the guinea pig and the animals were perfusion-fixed 48 h later...

journal_title：Neuroscience letters

authors： Keller JT,Bubel HC,Wander AH,Tierney BE

更新日期：1991-01-02 00:00:00

abstract：:We present a comprehensive analysis of the change in event-related potential (ERP) due to task difficulty during a visual oddball task. Specifically, we investigated the inter-subject difference in difficulty-related change of ERP patterns using single-trial ERP analysis focusing on P300 and P2 components. ERPs were r...

journal_title：Neuroscience letters

authors： Kim KH,Kim JH,Yoon J,Jung KY

更新日期：2008-11-14 00:00:00

abstract：:By using the whole-cell recording technique the Na+ current in cultured melanotrophs of the adult rat pituitary was studied. The Na+ current was eliminated by 1 microM TTX and its equilibrium potential confirmed that it was carried predominantly by Na+. The activation threshold was near -40 mV and half-maximal activat...

journal_title：Neuroscience letters

authors： Kehl SJ

更新日期：1994-01-03 00:00:00

abstract：:This study deals with the coordination of bilateral synchronous and asynchronous hand movements. Cooperative hand movements (e.g. opening a bottle) were shown to be coordinated by a neural coupling, reflected in the appearance of reflex responses in forearm muscles of both sides to unilateral arm nerve stimulation. Th...

journal_title：Neuroscience letters

authors： Köchli S,Scharfenberger T,Dietz V

更新日期：2020-02-16 00:00:00

abstract：:Gamma-band oscillations are related to sensory information processing and attention. To further illuminate the relationship of gamma-band activity and selective somatic attention, we have studied the effects of direction of attention on the stimuli of somatosensory evoked potentials. Responses during focused attention...

journal_title：Neuroscience letters

authors： Gobbelé R,Waberski TD,Schmitz S,Sturm W,Buchner H

更新日期：2002-07-12 00:00:00

abstract：:Pharmacological blocking agents were used to assess the contributions of different K(+)-currents to spike-repolarization and early spike-afterhyperpolarization recorded in dissociated, tissue-cultured rat superior cervical sympathetic neurones using both patch-clamp and impalement microelectrode techniques. Effects of...

journal_title：Neuroscience letters

authors： Marsh SJ,Brown DA

更新日期：1991-12-09 00:00:00

abstract：:Remembering contextual aspects of an event (recollection) is an important function subserved by episodic memory. It has recently been shown that the electrophysiological correlates of recollection differ depending upon the type of information subjects retrieve from episodic memory. In the current study, we investigate...

journal_title：Neuroscience letters

authors： Peters J,Daum I

更新日期：2009-05-01 00:00:00

abstract：:We investigated the effects of a representative anti-epileptic or anti-psychotic drug, carbamazepine (CBZ), on the induction of long-term potentiation (LTP) in the perforant path-dentate gyrus pathway in 15 chronically prepared rabbits. Pharmacokinetically injected low-dose CBZ, which produced steady serum levels of 2...

journal_title：Neuroscience letters

authors： Kubota T,Jibiki I,Fukushima T,Kurokawa K,Yamaguchi N

更新日期：1994-03-28 00:00:00

abstract：:Previous experiments have shown that arginine vasopressin (AVP) released within the septal brain area of adult male rats in response to defined stressor exposure is involved in emotionality-related behavior. We report here that a 10-min forced swimming session stimulated the release of glutamate, aspartate, arginine, ...

journal_title：Neuroscience letters

authors： Singewald N,Ebner K,Landgraf R,Wotjak CT,Engelmann M

更新日期：1999-12-17 00:00:00

abstract：:Neurotrophic factors regulate neuronal survival and differentiation and control neurite outgrowth by binding to tyrosine kinase receptors, the Trks, and a tumor necrosis factor (TNF) receptor-like molecule, p75 neurotrophin receptor. A proinflammatory cytokine, TNF, also affects survival and apoptotic death in neurona...

journal_title：Neuroscience letters

authors： Furuno T,Nakanishi M

更新日期：2006-01-16 00:00:00

abstract：:We studied axonal branching of 14 parabrachial nucleus neurons, activated antidromically from 2 of the 3 stimulation sites, i.e. the ipsi- and contralateral thalamic taste area (TTAs) and the ipsilateral central nucleus of the amygdala (CA). Making use of antidromic latencies, collision times and refractory periods at...

journal_title：Neuroscience letters

authors： Hayama T,Ogawa H

更新日期：1987-12-16 00:00:00

abstract：AIMS:To test the hypothesis that uridine 5'-triphosphate (UTP) had a protective effect on cerebral ischemia reperfusion (IR) injury in rats. METHODS:Ischemia was induced by intraluminal suture of middle cerebral artery occlusion (MCAO). UTP solution was delivered through an indwelling tail venous catheter via microinf...

journal_title：Neuroscience letters

authors： Tian ML,Zou Z,Yuan HB,Wang CC,Zhu QF,Xu HT,Gao X,Shi XY

更新日期：2009-11-06 00:00:00

abstract：:Prominent accounts of decision making state that decisions are made on the basis of an accumulation of sensory evidence, orchestrated by networks of prefrontal and parietal neural populations. Here we assess whether these findings generalize to decisions on self-motion. Participants were presented with whole body yaw ...

journal_title：Neuroscience letters

authors： de Winkel KN,Nesti A,Ayaz H,Bülthoff HH

更新日期：2017-07-27 00:00:00

abstract：:Smoking cessation strategies are of prime medical importance. Despite availability of various pharmacological agents in combating addiction to nicotine, more effective medications are needed. Based on recent findings, the glutamatergic system in the brain may provide novel targets. Here, we evaluated the effects of ac...

journal_title：Neuroscience letters

authors： Rezvani AH,Tizabi Y,Slade S,Getachew B,Levin ED

更新日期：2018-03-06 00:00:00

abstract：:Vigabatrin (VGB, gamma-vinyl-gamma-aminobutyric acid (GABA)), an irreversible inhibitor of GABA transaminase, increases regional inhibitory effects by elevating GABA concentration and reducing glutamate synthesis. In the present study, changes in glutamate dehydrogenase (GDH) activity and its immunoreactivity in the s...

journal_title：Neuroscience letters

authors： Kang TC,An SJ,Park SK,Hwang IK,Choi SY,Kwon OS,Won MH

更新日期：2003-04-10 00:00:00

abstract：:Axons in chronically demyelinated spinal cord lesions, induced by ethidium bromide injection, display patches of intramembranous particles and indentations resembling nodal and paranodal axolemmal specializations respectively. Both occur in the marginal region of the lesions where the demyelinated axons are intimately...

journal_title：Neuroscience letters

authors： Rosenbluth J,Blakemore WF

更新日期：1984-07-27 00:00:00

abstract：:Aphasia is a highly disabling language disorder usually caused by a left stroke brain damage. Even if traditional language therapies have been proved to induce an adequate clinical recovery, a large percentage of patients are left with chronic deficits at 6 months post-stroke. Therefore, new strategies to common speec...

journal_title：Neuroscience letters

authors： Marangolo P

更新日期：2020-02-06 00:00:00