Enhanced population responses in the basolateral amygdala of kainate-treated, epileptic rats in vitro.

abstract：:Evidence suggests that high peripheral beta-amyloid (Abeta)(1-40) levels and low ratios of Abeta(1-42)/Abeta(1-40) are associated with increased risk for Alzheimer's disease (AD). In this cross-sectional design, serum and plasma samples from 67 AD patients and 146 controls (similar in age and gender) were evaluated us...

journal_title：Neuroscience letters

authors： Abdullah L,Paris D,Luis C,Quadros A,Parrish J,Valdes L,Keegan AP,Mathura V,Crawford F,Mullan M

更新日期：2007-11-27 00:00:00

abstract：:The expression of dystrophin-protein 71 (Dp71) was investigated during nerve growth factor (NGF) induced differentiation of PC12 cells. A semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) assay was designed to measure Dp71 mRNA, whereas the Dp71 protein amount was evaluated by immunoblot analy...

journal_title：Neuroscience letters

authors： Cisneros B,Rendon A,Genty V,Aranda G,Marquez F,Mornet D,Montañez C

更新日期：1996-08-02 00:00:00

abstract：:Estrogen effects on pineal secretion of melatonin are controversial. Some feel that estrogen inhibits melatonin output in vitro but not in vivo. Melatonin levels vary with the age in chickens where circulating estrogen levels also vary. Laying hens have minimal melatonin levels and maximal serum iron concentrations. T...

journal_title：Neuroscience letters

authors： Pablos MI,Agapito MT,Recio JM,Pérez-Gallardo L,Córdova MD,Mori JO

更新日期：1993-09-03 00:00:00

abstract：:Muscle fatigue affects muscle strength and postural control. However, it is not known whether impaired postural control after fatiguing muscular exercise depends on the nature of the muscle contraction. To answer this question, the present study analyzes changes in postural control after two fatiguing exercises of equ...

journal_title：Neuroscience letters

authors： Paillard T,Maitre J,Chaubet V,Borel L

更新日期：2010-06-14 00:00:00

abstract：:This study evaluates the neuroprotective properties of some voltage-sensitive sodium channel blockers in a model of focal ischaemia. After curative treatment (0.5 and 24.5 h after insult), well known voltage-sensitive sodium channel blockers, phenytoin (2 x 100 mg/kg i.p.), carbamazepine (2 x 50 mg/kg i.p.), lamotrigi...

journal_title：Neuroscience letters

authors： Rataud J,Debarnot F,Mary V,Pratt J,Stutzmann JM

更新日期：1994-05-19 00:00:00

abstract：:Normal rats tend to respond to a sudden burst of noise or flash of light with slightly less startle when they are engaged in active behaviour at the time of presentation. This effect is vastly more pronounced in animals with lesions of the superior colliculus. These results are taken as support for a theory implicatin...

journal_title：Neuroscience letters

authors： Goodale MA,Milner AD,Rose JE

更新日期：1975-12-01 00:00:00

abstract：:An increase in the arthritis index as a marker of chronic inflammation and suppression of food intake are observed in adjuvant arthritic (AA) rats. Our previous study demonstrated that central oxytocin (OXT)-ergic pathways were activated potently in AA rats. In the present study, OXT-saporin (SAP) cytotoxin, which che...

journal_title：Neuroscience letters

authors： Matsuura T,Kawasaki M,Hashimoto H,Yoshimura M,Motojima Y,Saito R,Ueno H,Maruyama T,Sabanai K,Mori T,Ohnishi H,Sakai A,Ueta Y

更新日期：2016-05-16 00:00:00

abstract：:Estrogen was shown to promote neuronal survival against several neurotoxic insults including β-amyloid (Aβ). The proposed mechanism includes the activation of the mitogen activated protein kinase/extracellular signal-regulated kinase (Mapk/Erk), phosphatidylinositol 3-kinase/Akt pathways and the upregulation of antiap...

journal_title：Neuroscience letters

authors： Mateos L,Persson T,Katoozi S,Gil-Bea FJ,Cedazo-Minguez A

更新日期：2012-01-11 00:00:00

abstract：:The first psychotic episode is classically viewed as a critical period which management is important in determining the long-term outcome of the schizophrenia (SCZ). For this reason, the duration of untreated illness (DUI), defined as the interval between the onset of the psychiatric disorder and the administration of...

journal_title：Neuroscience letters

authors： Murru A,Carpiniello B

更新日期：2018-03-16 00:00:00

abstract：:Glia are key regulators of inflammatory responses within the central nervous system (CNS) following infection or trauma. We have previously demonstrated the ability of activated astrocytes to rapidly produce pro-inflammatory mediators followed by a transition to an anti-inflammatory cytokine production profile that in...

journal_title：Neuroscience letters

authors： Burmeister AR,Johnson MB,Marriott I

更新日期：2019-08-24 00:00:00

abstract：:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) may involve many target organs with relevant variability among affected individuals. We performed a multi-organ assessment tapping nervous system, skeletal muscle and cardiovascular system in thirty-nine individuals be...

journal_title：Neuroscience letters

authors： Ragno M,Pianese L,Cacchiò G,Manca A,Scarcella M,Silvestri S,Di Marzio F,Caiazzo AR,Silvaggio F,Tasca G,Mirabella M,Trojano L

更新日期：2012-01-06 00:00:00

abstract：:We compared cerebrospinal fluid (CSF) apolipoprotein (apo) A-I and apo E concentrations in early- and late-onset Alzheimer's disease (EOAD (n = 11), LOAD (n = 15), respectively) with those in control subjects (n = 23). CSF apo A-I levels in both EOAD and LOAD were consistent with control subjects. However, CSF apo E l...

journal_title：Neuroscience letters

authors： Song H,Saito K,Seishima M,Noma A,Urakami K,Nakashima K

更新日期：1997-08-15 00:00:00

abstract：:Diffusion MRI studies characterizing the changes in white matter (WM) due to vascular cognitive impairment, which includes all forms of small vessel disease are reviewed. We reviewed the usefulness of diffusion methods in discriminating the affected WM regions and its relation to cognitive impairment. These studies we...

journal_title：Neuroscience letters

authors： Raja R,Rosenberg G,Caprihan A

更新日期：2019-02-16 00:00:00

abstract：:The rat spinal cord slice preparation has been used to investigate the sensitivity of deep dorsal horn neurones to the excitatory amino acids N-methyl-D-aspartate (NMDA), quisqualate and L-glutamate. Intracellular recordings were made from 44 neurones in laminae III-VI of 14- to 16-day rats. Superfusion of quisqualate...

journal_title：Neuroscience letters

authors： King AE,Thompson SW,Urban L,Woolf CJ

更新日期：1988-07-08 00:00:00

abstract：:In the present study we sought to investigate the signal transduction mechanisms that underlie the alpha2-adrenergic receptor (AR)-induced, subtype-specific neuronal differentiation of PC12 cells. Alpha2-ARs induced NF-kappaB transcriptional activity and p21(waf-1) gene transcription in the same subtype-specific manne...

journal_title：Neuroscience letters

authors： Lymperopoulos A,Karkoulias G,Koch WJ,Flordellis CS

更新日期：2006-07-24 00:00:00

abstract：:To investigate the relationship between apolipoprotein E (APOE) polymorphisms and the severity of traumatic brain injury (TBI) in acute stage in the cohort of mainland Chinese patients. We prospectively identified admissions to the two neurosurgical departments for head injury. A total of 110 subjects with TBI (80 mal...

journal_title：Neuroscience letters

authors： Jiang Y,Sun X,Xia Y,Tang W,Cao Y,Gu Y

更新日期：2006-11-13 00:00:00

abstract：:Changes in the activity of the autonomic nervous system are good indicators of alterations in physiological phenomena such as the body temperature, blood glucose, blood pressure. Hesperidin, a flavanone known as vitamin P, has been shown to reduce the levels of serum lipids, cholesterol, and blood pressure. However, h...

journal_title：Neuroscience letters

authors： Shen J,Nakamura H,Fujisaki Y,Tanida M,Horii Y,Fuyuki R,Takumi H,Shiraishi K,Kometani T,Nagai K

更新日期：2009-09-11 00:00:00

abstract：:Muscle fatigue is known to be associated with a deteriorated muscle coordination and impaired movement performance in variety of voluntary movements. The aim of this study was to investigate the generally underexplored effect of muscle fatigue on both the coordination between grip force (GF; the force component perpen...

journal_title：Neuroscience letters

authors： Emge N,Prebeg G,Uygur M,Jaric S

更新日期：2013-08-29 00:00:00

abstract：:Antioxidants may delay or prevent neural diseases. Depletion of the non-enzymatic antioxidant, glutathione, in a mouse model was produced by inhibiting its rate-limiting enzyme, gamma-glutamylcysteine synthetase, for 7 weeks. Ileum and colon were obtained from treated and control (saline) mice. Glutathione levels and ...

journal_title：Neuroscience letters

authors： Koch TR,Fink JG,Ruan E,Petro A,Opara EC

更新日期：1997-10-10 00:00:00

abstract：:Novel paired ependymal ridges (EPRS) have been identified in the ventrolateral wall of the cerebral aqueduct of the rat. Scanning electron microscopic techniques revealed that the dorsolateral and ventromedial ridges differ from each other in surface morphology. Using the PAP immunohistochemical technique, the EPRS de...

journal_title：Neuroscience letters

authors： Welsh MG,Beitz AJ

更新日期：1981-11-18 00:00:00

abstract：:Central serotonergic neurotransmission has been implicated in the aetiology of ethanol tolerance and dependence. Cellular expression of the serotonin transporter and serotonin reuptake is modulated via a polymorphic, repetitive element in the 5'-flanking regulatory region of the serotonin transporter gene (5-HTTLPR). ...

journal_title：Neuroscience letters

authors： Türker T,Sodmann R,Goebel U,Jatzke S,Knapp M,Lesch KP,Schuster R,Schütz H,Weiler G,Stöber G

更新日期：1998-06-05 00:00:00

abstract：:The specific phosphatase inhibitor, Calyculin-A (CL-A), decreases high-K stimulated catecholamine secretion in bovine chromaffin cells. This effect can be split into two components: one needs long exposures to the drug to be elicited, and is sensitive to the protein kinase-inhibitor K252a; the other is observed after ...

journal_title：Neuroscience letters

authors： Gutiérrez LM,Viniegra S,Quintanar JL,Reig JA,Sala F

更新日期：1994-08-29 00:00:00

abstract：:We investigated the possibility of obtaining an anteroposterior body response to galvanic vestibular stimulation (GVS) by applying an equivalent stimulus to both sides of the vestibular apparatus. An original 'double fronto-mastoidal' stimulation was used on eight subjects standing with their head facing forwards. Bot...

journal_title：Neuroscience letters

authors： Séverac Cauquil A,Gervet MF,Ouaknine M

更新日期：1998-03-27 00:00:00

abstract：:The voltage dependency of the ON and the OFF components of transient amacrine cell responses was studied using two-electrode voltage-clamp and current-clamp techniques in the isolated retina of the carp. The two independent approaches gave similar data. When cells were voltage clamped near their resting potentials, bo...

journal_title：Neuroscience letters

authors： Djamgoz MB,Low JC,Saito T,Toyoda JI,Yamada M

更新日期：1996-08-23 00:00:00

abstract：:Mouse acetylcholine receptors (AChRs) consisting of either the embryonic form (2 alpha, 1 beta, 1 delta and 1 gamma) or the adult form (2 alpha, 1 beta, 1 delta and 1 epsilon) were expressed in Xenopus laevis oocytes. As expected, the single channel conductance was approximately 52 pS and the exponential decay time co...

journal_title：Neuroscience letters

authors： Liu E,Hamill OP,Salpeter MM

更新日期：1994-06-06 00:00:00

abstract：:The effects of gonadal steroids on serotonin (5-HT) synthesis and metabolism in the early developing brain were investigated. Seven-day-old (7 days post-hatch) tilapia, Oreochromis mossambicus were continuously treated with 17beta-estradiol (E2), methyltestosterone (MT) and para-chlorophenylalanine (p-PCA) up to the a...

journal_title：Neuroscience letters

authors： Tsai CL,Wang LH

更新日期：1999-04-02 00:00:00

abstract：:Recent evidence has suggested that down-regulation of somatostatin (SST) expression in the human brain during early stages of aging leads to an elevation in the steady-state levels of Abeta and therefore may be involved in Alzheimer's disease (AD) progression. We hypothesized that alterations in the SST gene might alt...

journal_title：Neuroscience letters

authors： Xue S,Jia L,Jia J

更新日期：2009-11-13 00:00:00

abstract：:Functional neuroimaging suggests asymmetries of memory encoding and retrieval in the prefrontal lobes, but different hypotheses have been presented concerning the nature of prefrontal hemispheric specialization. We studied an associative memory task involving pairs of Kanji (Chinese) pictographs and unfamiliar abstrac...

journal_title：Neuroscience letters

authors： Epstein CM,Sekino M,Yamaguchi K,Kamiya S,Ueno S

更新日期：2002-03-01 00:00:00

abstract：:Sphere-forming assays are widely used for the propagation, characterization and manipulation of adult brain-derived stem- and progenitor cells. However despite the broad application of this cell culture system in neural stem cell- and brain tumor research, no standardized protocols exist. Variations in experimental pr...

journal_title：Neuroscience letters

authors： Schramm J,Schulte D

更新日期：2014-03-06 00:00:00

abstract：:Auditory learning induces frequency-specific plasticity in the auditory cortex. Both the auditory cortex and thalamus are involved in the cortical plasticity; however, the precise role of the intracortical circuity remains unclear until the contributions of the thalamocortical inputs are controlled. Here, we induced c...

journal_title：Neuroscience letters

authors： Kong L,Wang S,Liu X,Li L,Zeeman M,Yan J

更新日期：2018-03-06 00:00:00