Abstract:
:Peroxisomal activities were examined in liver and brain of lactating neonatal rats of mothers maintained on ciprofibrate, a peroxisomal proliferator. The activities of DHAP-acyltransferase, alkyl-DHAP synthetase and the beta-oxidation of palmitic and lignoceric acids increased in brain by 3.9, 2.2, 4.3 and 3.2 fold and in liver by 3.2, 2.6, 6.2 and 2.5 fold, respectively, of lactating pups from mothers on ciprofibrate diet as compared to controls. Ciprofibrate treatment increased the peroxisomal enzyme activities in both brain and liver of lactating neonatal rats demonstrating that ciprofibrate or its metabolite(s) transmitted through the mother's milk can effectively induce peroxisomal proliferation.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Singh I,Lazo Odoi
10.1016/0304-3940(92)90934-ykeywords:
subject
Has Abstractpub_date
1992-04-27 00:00:00pages
283-6issue
2eissn
0304-3940issn
1872-7972pii
0304-3940(92)90934-Yjournal_volume
138pub_type
杂志文章abstract:BACKROUND:A relatively small number of genetic variants are implicated to pathophysiology of intracerebral hemorrhage (ICH). Aquaporin-4 (AQP4) has been reported to be implicated in the pathophysiological processes of ICH development. OBJECTIVE:To examine the role of AQP4 gene region polymorphisms on the ICH risk. ME...
journal_title:Neuroscience letters
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更新日期:2019-03-23 00:00:00
abstract::Depleted uranium has numerous industrial and military uses. Contamination by inhalation of airborne compounds is probably the most important route of exposure. In humans, there are no data clearly demonstrating neurotoxicity of uranium, yet some experimental studies suggest a link between neurological toxicity and ura...
journal_title:Neuroscience letters
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更新日期:2005-12-16 00:00:00
abstract::The somatosensory homunculus has been identified during stimulation of median (at wrist and elbow), femoral, tibial and pudendal nerves of the left hemibody via the neuromagnetic imaging technique. The somatic representations of different body districts have been localized in the somatosensory cortex, by means of an e...
journal_title:Neuroscience letters
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更新日期:1991-01-02 00:00:00
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journal_title:Neuroscience letters
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更新日期:2004-08-19 00:00:00
abstract::Idiopathic cervical dystonia (ICD) is a movement disorder often resulting in profound disability and pain. Treatment options include oral medications or other invasive procedures, whereas intractable ICD has been shown to respond to invasive (deep) brain stimulation. In the present blinded, placebo-controlled case stu...
journal_title:Neuroscience letters
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更新日期:2013-01-15 00:00:00
abstract::To clarify the possible role of in the in vivo toxic effects of 6-hydroxydopamine (6-OHDA), especially caspase activations, we examined its effects on striatal lipid peroxidation (LPO) and caspase activations in 6-OHDA-lesioned mice. Both dopamine (DA) levels and DA turnover were significantly changed by the 6-OHDA i....
journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2015-03-30 00:00:00
abstract::Near-infrared spectroscopy (NIRS) is a non-invasive optical technique which has been successfully used to register substantial cerebral ischemia. There are indications that NIRS is sensible enough to detect also small metabolic changes during the performance of cognitive tasks. In the present study, two-channel NIRS o...
journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
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更新日期:1977-04-01 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(86)90446-5
更新日期:1986-09-25 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(95)11514-w
更新日期:1995-05-05 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(98)00238-9
更新日期:1998-04-24 00:00:00
abstract::In elucidating the possible involvement of histamine (His) in hyperalgesia to heat, the effects of His on the heat response of testicular polymodal receptors were studied in vitro in canine testis-spermatic nerve preparations. His (100 and 1000 microM) induced discharges > 0.5 impulses/s (high-responders) in about one...
journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1994-02-28 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1992-11-09 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(91)90781-n
更新日期:1991-06-24 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2008.04.090
更新日期:2008-07-04 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1996-06-14 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1988-12-19 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章,评审
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(83)90445-7
更新日期:1983-06-30 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2017.10.042
更新日期:2018-01-01 00:00:00
abstract::Using antibodies to somatostatin in combination with the avidin-biotin immunohistochemical method, the laminar distribution and morphology of somatostatin-like (SOM-L) immunoreactive cells have been studied in the hippocampal formation of the rat. SOM-L positive cells are present throughout the longitudinal axis of th...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(82)90185-9
更新日期:1982-12-31 00:00:00
abstract::Oxytoxin (OT) promotes social behavior and reduces anxiety. A great number of studies suggest that OT plays a role in learning and memory processes in animals and humans. Fear memories are rendered labile and prone to modification after reactivation and a restabilization and reconsolidation process is necessary for fu...
journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2015-05-06 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(98)00370-x
更新日期:1998-06-12 00:00:00
abstract::Spontaneous gasps were recorded in pentobarbitone-anesthetized adult cats. Mean interval between gasps in 11 cats with their buffer nerves intact was of 65 sec; it was significantly prolonged to 174 sec after unilateral carotid neurotomy and to 403 sec after bilateral carotid neurotomy. Additional sectioning of both a...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(80)90110-x
更新日期:1980-01-01 00:00:00
abstract::We reported previously that administration of 1-oleoyl-2-docosahexaenoyl-sn-glycero-3-phosphorylcholine (ODHPC), a kind of phosphatidylcholine, enhanced discriminatory shock avoidance learning in rats. Since long-term potentiation (LTP) of the hippocampus has been suggested to be a physiological substrate of some form...
journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1999-01-29 00:00:00
abstract::It is believed that subjects with high trait anxiety levels tend to present state anxiety reactions with greater intensity than individuals with low trait anxiety levels. In order to verify if this premise is valid for animal models of anxiety, the present work investigated the possible correlation between two behavio...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2008.11.037
更新日期:2009-02-06 00:00:00
abstract::Unilateral intraplantar injections (1/day for 3 days) of 4 mu g nerve growth factor (NGF) into the rat hindpaw increased the expression of prepro-tachykinin (PPT)- and prepro-calcitonin gene-related peptide (ppCGRP)-mRNA in bilateral L5 dorsal root ganglia (DRGs). This was accompanied by an increase of CGRP-like immun...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(95)12287-7
更新日期:1996-01-26 00:00:00
abstract::Addition of vasopressin to hypothalamo-neurohypophysial explants in vitro increased cyclic AMP accumulation whereas exogenous oxytocin decreased cyclic AMP. An opposite response pattern was observed in the neural lobe of the pituitary where vasopressin decreased and oxytocin increased cyclic AMP accumulation. Forskoli...
journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1990-07-03 00:00:00