Peroxisomal enzyme activities in brain and liver of pups of lactating mothers treated with ciprofibrate.

Abstract:

:Peroxisomal activities were examined in liver and brain of lactating neonatal rats of mothers maintained on ciprofibrate, a peroxisomal proliferator. The activities of DHAP-acyltransferase, alkyl-DHAP synthetase and the beta-oxidation of palmitic and lignoceric acids increased in brain by 3.9, 2.2, 4.3 and 3.2 fold and in liver by 3.2, 2.6, 6.2 and 2.5 fold, respectively, of lactating pups from mothers on ciprofibrate diet as compared to controls. Ciprofibrate treatment increased the peroxisomal enzyme activities in both brain and liver of lactating neonatal rats demonstrating that ciprofibrate or its metabolite(s) transmitted through the mother's milk can effectively induce peroxisomal proliferation.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Singh I,Lazo O

doi

10.1016/0304-3940(92)90934-y

keywords:

subject

Has Abstract

pub_date

1992-04-27 00:00:00

pages

283-6

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(92)90934-Y

journal_volume

138

pub_type

杂志文章
  • AQP4 tag SNPs in patients with intracerebral hemorrhage in Greek and Polish population.

    abstract:BACKROUND:A relatively small number of genetic variants are implicated to pathophysiology of intracerebral hemorrhage (ICH). Aquaporin-4 (AQP4) has been reported to be implicated in the pathophysiological processes of ICH development. OBJECTIVE:To examine the role of AQP4 gene region polymorphisms on the ICH risk. ME...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2018.12.025

    authors: Dardiotis E,Siokas V,Marogianni C,Aloizou AM,Sokratous M,Paterakis K,Dardioti M,Grigoriadis S,Brotis A,Kapsalaki E,Fountas K,Jagiella J,Hadjigeorgiou GM

    更新日期:2019-03-23 00:00:00

  • Bioaccumulation and behavioural effects of depleted uranium in rats exposed to repeated inhalations.

    abstract::Depleted uranium has numerous industrial and military uses. Contamination by inhalation of airborne compounds is probably the most important route of exposure. In humans, there are no data clearly demonstrating neurotoxicity of uranium, yet some experimental studies suggest a link between neurological toxicity and ura...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.07.051

    authors: Monleau M,Bussy C,Lestaevel P,Houpert P,Paquet F,Chazel V

    更新日期:2005-12-16 00:00:00

  • Neuromagnetic somatosensory homunculus: a non-invasive approach in humans.

    abstract::The somatosensory homunculus has been identified during stimulation of median (at wrist and elbow), femoral, tibial and pudendal nerves of the left hemibody via the neuromagnetic imaging technique. The somatic representations of different body districts have been localized in the somatosensory cortex, by means of an e...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90647-c

    authors: Narici L,Modena I,Opsomer RJ,Pizzella V,Romani GL,Torrioli G,Traversa R,Rossini PM

    更新日期:1991-01-02 00:00:00

  • The Ebbinghaus illusion affects on-line movement control.

    abstract::Changes in the planning and control of discrete aiming movements in response to the introduction and removal of the Ebbinghaus size-contrast illusion were examined. Movements were executed faster to targets that appeared larger following movement initiation. The differences in movement time were associated with the po...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.05.056

    authors: Handlovsky I,Hansen S,Lee TD,Elliott D

    更新日期:2004-08-19 00:00:00

  • Transcranial alternating current stimulation reduces symptoms in intractable idiopathic cervical dystonia: a case study.

    abstract::Idiopathic cervical dystonia (ICD) is a movement disorder often resulting in profound disability and pain. Treatment options include oral medications or other invasive procedures, whereas intractable ICD has been shown to respond to invasive (deep) brain stimulation. In the present blinded, placebo-controlled case stu...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.11.007

    authors: Angelakis E,Liouta E,Andreadis N,Leonardos A,Ktonas P,Stavrinou LC,Miranda PC,Mekonnen A,Sakas DE

    更新日期:2013-01-15 00:00:00

  • Molecular basis of 6-hydroxydopamine-induced caspase activations due to increases in oxidative stress in the mouse striatum.

    abstract::To clarify the possible role of in the in vivo toxic effects of 6-hydroxydopamine (6-OHDA), especially caspase activations, we examined its effects on striatal lipid peroxidation (LPO) and caspase activations in 6-OHDA-lesioned mice. Both dopamine (DA) levels and DA turnover were significantly changed by the 6-OHDA i....

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2006.08.021

    authors: Tanaka K,Ogawa N,Asanuma M

    更新日期:2006-12-20 00:00:00

  • Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms?

    abstract::Cisplatin, oxaliplatin, paclitaxel, vincristine and bortezomib are some of the most effective drugs successfully employed (alone or in combinations) as first-line treatment for common cancers. However they often caused severe peripheral neurotoxicity and neuropathic pain. Structural deficits in Dorsal Root Ganglia and...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2014.10.014

    authors: Carozzi VA,Canta A,Chiorazzi A

    更新日期:2015-06-02 00:00:00

  • Feedback delays eliminate auditory-motor learning in speech production.

    abstract::Neurologically healthy individuals use sensory feedback to alter future movements by updating internal models of the effector system and environment. For example, when visual feedback about limb movements or auditory feedback about speech movements is experimentally perturbed, the planning of subsequent movements is a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2015.02.012

    authors: Max L,Maffett DG

    更新日期:2015-03-30 00:00:00

  • Right frontal activation during the continuous performance test assessed with near-infrared spectroscopy in healthy subjects.

    abstract::Near-infrared spectroscopy (NIRS) is a non-invasive optical technique which has been successfully used to register substantial cerebral ischemia. There are indications that NIRS is sensible enough to detect also small metabolic changes during the performance of cognitive tasks. In the present study, two-channel NIRS o...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)13416-4

    authors: Fallgatter AJ,Strik WK

    更新日期:1997-02-21 00:00:00

  • The effects of unilateral 6-hydroxydopamine lesions in the substantia nigra on hippocampal noradrenaline-induced feeding and other behaviour in the rat.

    abstract::The latency, duration of feeding and number of feeding periods recorded from rats after noradrenaline injection to the hippocampus show little change after unilateral 6-hydroxydopamine injections to the substantia nigra. It is suggested that 6-hydroxydopamine-induced weight losses result from non-specific effects of i...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(77)90194-x

    authors: Oades RD

    更新日期:1977-04-01 00:00:00

  • 4-Aminopyridine-mediated increase in long-term potentiation in CA1 of the rat hippocampus.

    abstract::The effect of 4-aminopyridine (4-AP) on long-term potentiation (LTP) was studied in the hippocampal slice preparation of the rat. Field excitatory postsynaptic potentials (EPSPs) were recorded and evoked in the stratum radiatum of the CA1. Both the low frequency EPSP and LTP of the EPSP were significantly increased by...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90446-5

    authors: Lee WL,Anwyl R,Rowan M

    更新日期:1986-09-25 00:00:00

  • The intra-adrenal distribution of intrinsic and extrinsic nitrergic nerve fibres in the rat.

    abstract::The intra-adrenal distribution of nitric oxide synthase (NOS)-immunoreactive nerve fibres was studied in rats subjected to various denervations. Splanchnic nerve section eliminated the NOS-immunoreactive nerve fibres which innervate adrenal chromaffin and neuronal cells. It did not affect those innervating blood vesse...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)11514-w

    authors: Afework M,Ralevic V,Burnstock G

    更新日期:1995-05-05 00:00:00

  • Blockade of brain type II interleukin-1 receptors potentiates IL1beta-induced anorexia in mice.

    abstract::Interleukin-1beta (IL1beta) peripheral activities are mediated by type I IL1 receptors (IL1RI), whereas type II IL1 receptors (IL1RII) act as 'decoy' targets. To study the functionality of IL1RII in the brain, mice were treated with an intracerebroventricular injection of a neutralising MoAb directed against IL1RII (4...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00238-9

    authors: Cremona S,Layé S,Dantzer R,Parnet P

    更新日期:1998-04-24 00:00:00

  • Histamine-induced sensitization of the heat response of canine visceral polymodal receptors.

    abstract::In elucidating the possible involvement of histamine (His) in hyperalgesia to heat, the effects of His on the heat response of testicular polymodal receptors were studied in vitro in canine testis-spermatic nerve preparations. His (100 and 1000 microM) induced discharges > 0.5 impulses/s (high-responders) in about one...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90424-3

    authors: Mizumura K,Minagawa M,Koda H,Kumazawa T

    更新日期:1994-02-28 00:00:00

  • Localization of preprogalanin mRNA in the monkey hippocampal formation.

    abstract::The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, s...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90070-n

    authors: Evans HF,Huntley GW,Morrison JH,Shine J,Paxinos G

    更新日期:1992-11-09 00:00:00

  • Serotonergic involvement in the cardiovascular stimulation by thyrotropin-releasing hormone (TRH) in anesthetized rats.

    abstract::The cardiovascular effects of intracerebroventricularly administered thyrotropin-releasing hormone (TRH) were studied in anesthetized rats in the presence of serotonin (5-HT) depletion induced by pretreatments with p-chloroamphetamine (PCA) or p-chlorophenylalanine (PCPA). After PCA the reduction of the whole brain 5-...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90781-n

    authors: Nurminen ML,Paakkari I,Seppälä T

    更新日期:1991-06-24 00:00:00

  • Genetic deletion of Fatty Acid Amide Hydrolase results in improved long-term outcome in chronic autoimmune encephalitis.

    abstract::The enzyme Fatty Acid Amide Hydrolase (FAAH) is a key regulator of the endogenous levels of a family of biologically active lipid mediators, the fatty acid amides. These include anandamide, oleoyl ethanolamide and palmitoyl ethanolamide, and their effects are mediated by a variety of downstream targets including canna...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.04.090

    authors: Webb M,Luo L,Ma JY,Tham CS

    更新日期:2008-07-04 00:00:00

  • Differences in the composition of chromaffin granules in adrenaline and noradrenaline containing cells of bovine adrenal medulla.

    abstract::Several constituents of chromaffin granules were quantitatively determined in noradrenaline and adrenaline cells purified from bovine adrenal medulla. As far as secretory peptides are concerned noradrenaline granules contained slightly more secretogranin II, but much less chromogranin A than adrenaline granules. This ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(96)12712-9

    authors: Weiss C,Cahill AL,Laslop A,Fischer-Colbrie R,Perlman RL,Winkler H

    更新日期:1996-06-14 00:00:00

  • Cholinergic neurons from the dorsolateral pons project to the medial pons: a WGA-HRP and choline acetyltransferase immunohistochemical study.

    abstract::In this study we determined that cholinergic neurons from the lateral dorsal tegmental (LDT) and peribrachial pontine region (PPG) innervate the medial pontine reticular formation (medial PRF), a region involved in the generation of REM sleep. Wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) was injec...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(88)90625-8

    authors: Shiromani PJ,Armstrong DM,Gillin JC

    更新日期:1988-12-19 00:00:00

  • Why do so many genetic insults lead to Purkinje Cell degeneration and spinocerebellar ataxia?

    abstract::The genetically heterozygous spinocerebellar ataxias are all characterized by cerebellar atrophy and pervasive Purkinje Cell degeneration. Up to date, more than 35 functionally diverse spinocerebellar ataxia genes have been identified. The main question that remains yet unsolved is why do some many genetic insults lea...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2018.02.004

    authors: Huang M,Verbeek DS

    更新日期:2019-01-01 00:00:00

  • Glucagon-induced somatostatin release from perifused rat hypothalamus: calcium dependency and effect of cysteamine treatment.

    abstract::Somatostatin (SRIF) release from rat hypothalamus was investigated in vitro with a perifusion system. Glucagon (1 microM) and high potassium concentrations (56 mM) stimulated SRIF release in a calcium-dependent manner. Pretreatment of the rat with cysteamine (30 mg/100 g body weight, 7 h earlier) significantly reduced...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(83)90445-7

    authors: Shimatsu A,Kato Y,Matsushita N,Ohta H,Kabayama Y,Imura H

    更新日期:1983-06-30 00:00:00

  • Adiponectin modulates synaptic plasticity in hippocampal dentate gyrus.

    abstract::Recent studies have suggested the involvement of some metabolic hormones in memory formation and synaptic plasticity. Insulin dysfunction is known as an essential process in the pathogenesis of sporadic Alzheimer's disease (AD). In this study we examined whether adiponectin (ADN), as an insulin-sensitizing adipokine, ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.10.042

    authors: Pousti F,Ahmadi R,Mirahmadi F,Hosseinmardi N,Rohampour K

    更新日期:2018-01-01 00:00:00

  • Somatostatin-like immunoreactive neurons in the hippocampus: an immunocytochemical study in the rat.

    abstract::Using antibodies to somatostatin in combination with the avidin-biotin immunohistochemical method, the laminar distribution and morphology of somatostatin-like (SOM-L) immunoreactive cells have been studied in the hippocampal formation of the rat. SOM-L positive cells are present throughout the longitudinal axis of th...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(82)90185-9

    authors: Köhler C,Chan-Palay V

    更新日期:1982-12-31 00:00:00

  • Effects of oxytocin on the fear memory reconsolidation.

    abstract::Oxytoxin (OT) promotes social behavior and reduces anxiety. A great number of studies suggest that OT plays a role in learning and memory processes in animals and humans. Fear memories are rendered labile and prone to modification after reactivation and a restabilization and reconsolidation process is necessary for fu...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2015.03.030

    authors: Hou Y,Zhao L,Zhang G,Ding L

    更新日期:2015-05-06 00:00:00

  • Cerebrospinal fluid levels of alpha-tocopherol in patients with multiple sclerosis.

    abstract::We compared cerebrospinal fluid (CSF) and serum levels, and the CSF/serum ratio of alpha-tocopherol (vitamin E), measured by HPLC, in 36 patients with multiple sclerosis (MS) and 32 matched controls. The mean CSF vitamin E levels and the CSF/serum vitamin E ratio did not differ significantly between the two study grou...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00370-x

    authors: Jiménez-Jiménez FJ,de Bustos F,Molina JA,de Andrés C,Gasalla T,Ortí-Pareja M,Zurdo M,Porta J,Castellano-Millán F,Arenas J,Enríquez de Salamanca R

    更新日期:1998-06-12 00:00:00

  • Regulatory role of carotid nerve afferences upon the frequency and pattern of spontaneous gasp complexes.

    abstract::Spontaneous gasps were recorded in pentobarbitone-anesthetized adult cats. Mean interval between gasps in 11 cats with their buffer nerves intact was of 65 sec; it was significantly prolonged to 174 sec after unilateral carotid neurotomy and to 403 sec after bilateral carotid neurotomy. Additional sectioning of both a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(80)90110-x

    authors: Zuazo A,Zapata P

    更新日期:1980-01-01 00:00:00

  • Enhancement by 1-oleoyl-2-docosahexaenoyl phosphatidylcholine of long-term potentiation in the rat hippocampal CA1 region.

    abstract::We reported previously that administration of 1-oleoyl-2-docosahexaenoyl-sn-glycero-3-phosphorylcholine (ODHPC), a kind of phosphatidylcholine, enhanced discriminatory shock avoidance learning in rats. Since long-term potentiation (LTP) of the hippocampus has been suggested to be a physiological substrate of some form...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00965-3

    authors: Izaki Y,Hashimoto M,Arita J

    更新日期:1999-01-29 00:00:00

  • Trait and state anxiety in animal models: Is there correlation?

    abstract::It is believed that subjects with high trait anxiety levels tend to present state anxiety reactions with greater intensity than individuals with low trait anxiety levels. In order to verify if this premise is valid for animal models of anxiety, the present work investigated the possible correlation between two behavio...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.11.037

    authors: Goes TC,Antunes FD,Teixeira-Silva F

    更新日期:2009-02-06 00:00:00

  • Stimulation by nerve growth factor of neuropeptide synthesis in the adult rat in vivo: bilateral response to unilateral intraplantar injections.

    abstract::Unilateral intraplantar injections (1/day for 3 days) of 4 mu g nerve growth factor (NGF) into the rat hindpaw increased the expression of prepro-tachykinin (PPT)- and prepro-calcitonin gene-related peptide (ppCGRP)-mRNA in bilateral L5 dorsal root ganglia (DRGs). This was accompanied by an increase of CGRP-like immun...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)12287-7

    authors: Amann R,Sirinathsinghji DJ,Donnerer J,Liebmann I,Schuligoi R

    更新日期:1996-01-26 00:00:00

  • Vasopressin and oxytocin regulation of cyclic AMP accumulation in rat hypothalamo-neurohypophysial explants in vitro.

    abstract::Addition of vasopressin to hypothalamo-neurohypophysial explants in vitro increased cyclic AMP accumulation whereas exogenous oxytocin decreased cyclic AMP. An opposite response pattern was observed in the neural lobe of the pituitary where vasopressin decreased and oxytocin increased cyclic AMP accumulation. Forskoli...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(90)90076-l

    authors: Meeker RB,Michels KM,Hayward JN

    更新日期:1990-07-03 00:00:00