Caudal ventrolateral medullary projections to the nucleus of the solitary tract in the cat.

Abstract:

:The projections of neurons, in and around the A1 noradrenergic cell group of the caudal ventrolateral medulla (VLM), to nucleus of the solitary tract (NTS) were studied in the cat using the anterograde transport of Phaseolus vulgaris leucoagglutinin (PHA-L). PHA-L was micro-iontophoresed into the region of the A1 noradrenergic cell group and after a 7-17 day survival period animals were sacrificed and brainstem sections were processed for PHA-L or tyrosine hydroxylase (TH) immunoreactivity. PHA-L injections within the region of the A1 cell group resulted in labelled fibers with their presumptive terminal boutons primarily in the ipsilateral commissural and medial subnuclei of NTS. A light projection to the ipsilateral parvocellular lateral and ventrolateral subnuclei of the NTS complex was also observed. These data demonstrate that neurons in the region of the A1 noradrenergic cell group project to regions of NTS that receive cardiovascular afferent inputs and suggest that VLM may influence the activity of neurons in NTS involved in the reflex regulation of the circulation.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Roder S,Ciriello J

doi

10.1016/0304-3940(92)90506-3

keywords:

subject

Has Abstract

pub_date

1992-01-06 00:00:00

pages

161-4

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(92)90506-3

journal_volume

134

pub_type

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