Abstract:
:Neuropeptide Y (NPY)-immunoreactivity has been localized to a rich network of fibres in the uvea of guinea pig and rat. In the iris, NPY-immunoreactive nerves were present in iridial smooth muscle and around blood vessels; similarly throughout the choroid a dense network of NPY-immunoreactive fibres was found surrounding the choroidal vascularization. Following sympathectomy a marked decrease of NPY-immunoreactivity, in particular in the iris and less marked in the choroid, was noted, indicating that these fibres may originate at least in part from neuronal cell bodies in the superior cervical ganglion. The close relationship of the NPY-immunoreactive fibres to blood vessels in both anterior and posterior uvea is consistent with the established vasoconstrictor action of this peptide.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Terenghi G,Polak JM,Allen JM,Zhang SQ,Unger WG,Bloom SRdoi
10.1016/0304-3940(83)90417-2subject
Has Abstractpub_date
1983-11-21 00:00:00pages
33-8issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(83)90417-2journal_volume
42pub_type
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