Neuropeptide Y-immunoreactive nerves in the uvea of guinea pig and rat.

Abstract:

:Neuropeptide Y (NPY)-immunoreactivity has been localized to a rich network of fibres in the uvea of guinea pig and rat. In the iris, NPY-immunoreactive nerves were present in iridial smooth muscle and around blood vessels; similarly throughout the choroid a dense network of NPY-immunoreactive fibres was found surrounding the choroidal vascularization. Following sympathectomy a marked decrease of NPY-immunoreactivity, in particular in the iris and less marked in the choroid, was noted, indicating that these fibres may originate at least in part from neuronal cell bodies in the superior cervical ganglion. The close relationship of the NPY-immunoreactive fibres to blood vessels in both anterior and posterior uvea is consistent with the established vasoconstrictor action of this peptide.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Terenghi G,Polak JM,Allen JM,Zhang SQ,Unger WG,Bloom SR

doi

10.1016/0304-3940(83)90417-2

subject

Has Abstract

pub_date

1983-11-21 00:00:00

pages

33-8

issue

1

eissn

0304-3940

issn

1872-7972

pii

0304-3940(83)90417-2

journal_volume

42

pub_type

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