Time course of recovery of the somatosensory map following hindpaw sensory deprivation in the rat.

Abstract:

:Hindlimb sensory deprivation is known to induce a decrease in the cortical representation of hindpaw, and an increase in the size of the cutaneous receptive fields. The aim of the present study was to determine (i) the time-course of recovery when the rat retrieves a normal use of its limbs after a 14-day period of sensory disruption and (ii) whether a 1-day period of sensory deprivation is sufficient to induce a plasticity. Our results indicate that the remodelling of the cortical map was not observed after 1 day of sensory deprivation. On the other hand, the recovery was achieved after 6 h. These findings suggest that a procedure reducing sensory function resulted in reversible changes in the somatosensory cortex. The recovery was more rapid than the induction of plasticity.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Dupont E,Canu MH,Langlet C,Falempin M

doi

10.1016/s0304-3940(01)02050-x

keywords:

subject

Has Abstract

pub_date

2001-08-24 00:00:00

pages

121-4

issue

2

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(01)02050-X

journal_volume

309

pub_type

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