Abstract:
:By recording the locomotor activity rhythm of hagfish, Eptatretus burgeri, in which surgical lesions of the preoptic nucleus (PON) were made, we searched for the location of the circadian pacemaker in the hypothalamus. The characteristic rhythms were lost in animals lacking the anterior part of the hypothalamus, which includes the PON. Cuts in front of the PON did not affect the rhythm, but cuts behind the PON caused the animals to loose their rhythms. Destruction of the PON with a high-frequency lesion generator also caused loss of rhythms. These findings indicate that the pacemaker may be located in the PON, which has retinofugal connections.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Ooka-Souda S,Kadota T,Kabasawa Hdoi
10.1016/0304-3940(93)90850-ksubject
Has Abstractpub_date
1993-12-24 00:00:00pages
33-6issue
1-2eissn
0304-3940issn
1872-7972pii
0304-3940(93)90850-Kjournal_volume
164pub_type
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