Abstract：
:This study tested the hypothesis that cholinoceptive regions of the medial pontine reticular formation (mPRF), long known to play a role in regulating the sleep cycle, can also causally alter the respiratory cycle. In 4 cats, sleep and wakefulness were polygraphically recorded while simultaneous measures were taken of rate of breathing, tidal volume, minute ventilation, respiratory cycle timing, and end-tidal CO2 concentration. Respiration during naturally occurring rapid eye movement (REM) sleep was compared to breathing during wakefulness and during the REM sleep-like state (D Carb) caused by mPRF microinjections of the cholinergic agonist carbachol. The results demonstrate for the first time that non-respiratory regions of the cholinoceptive mPRF can cause statistically significant state-dependent alterations in respiration.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Lydic R,Baghdoyan HAdoi
10.1016/0304-3940(89)90080-3subject
Has Abstractpub_date
1989-07-31 00:00:00pages
211-6issue
2-3eissn
0304-3940issn
1872-7972pii
0304-3940(89)90080-3journal_volume
102pub_type
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doi：10.1016/j.neulet.2006.06.025
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doi：10.1016/s0304-3940(01)01890-0
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Neuroscience letters
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doi：10.1016/j.neulet.2013.03.014
更新日期：2013-05-24 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2009.10.033
更新日期：2009-12-25 00:00:00
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pub_type： 杂志文章
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2015.02.029
更新日期：2015-03-30 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(87)90269-2
更新日期：1987-12-04 00:00:00
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pub_type： 临床试验,杂志文章
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pub_type： 杂志文章
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journal_title：Neuroscience letters
pub_type： 杂志文章,meta分析
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更新日期：2013-04-29 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(90)90535-h
更新日期：1990-02-05 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(84)90217-9
更新日期：1984-01-27 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2004.09.077
更新日期：2005-01-03 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2014.04.041
更新日期：2014-06-24 00:00:00
abstract：:The neuron-specific phosphoprotein B-50 is a major substrate of kinase C in fetal nerve growth cones, neonatal neural and synaptosomal plasma membranes. B-50 is identical to a growth-associated protein GAP43. Similarly, increases in B-50 occur during rat brain development, neuronal differentiation and axon regeneratio...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(87)90216-3
更新日期：1987-12-16 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2017.08.042
更新日期：2017-09-29 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2005.05.043
更新日期：2005-09-16 00:00:00
abstract：:Dopamine receptor D4 (DRD4) is activated by the neurotransmitter dopamine and links to many neurological and psychiatric conditions because of its close relationship with prefrontal cortex and other important brain regions. To explore the possibility that genetic variants of DRD4 gene predispose to children with menta...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2012.02.017
更新日期：2012-05-10 00:00:00
abstract：:The extracellular concentrations of the lipid peroxidation product malonaldehyde (MDA) and the antioxidants ascorbic and uric acid were measured in rat brain in vivo using microdialysis coupled to HPLC with ultra violet spectrophotometry. Treatment with kainic acid at pH 4.1 (50 nmol) caused a significant increase in ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(95)12073-d
更新日期：1995-11-10 00:00:00
