Abstract:
:Dinucleotide repeat polymorphism has been observed in the promoter of the alpha-synuclein (alpha-SYN)/NAC precursor protein (NACP) gene. Alpha-SYN/NACP allele 3 (described by Xia et al. (Ann. Neurol., 40 (1996) 207), equivalent to allele 1 described by Krüger et al. (Ann. Neurol. 45 (1999) 611) is reported to be significantly more frequent among patients with sporadic Parkinson's disease (sPD) than controls. In this study, we genotyped the same alpha-SYN/NACP polymorphism in Japanese sPD patients and healthy controls, but found that any aliele showed no significant difference between the two groups.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Izumi Y,Morino H,Oda M,Maruyama H,Udaka F,Kameyama M,Nakamura S,Kawakami Hdoi
10.1016/s0304-3940(01)01557-9keywords:
subject
Has Abstractpub_date
2001-03-09 00:00:00pages
125-7issue
2eissn
0304-3940issn
1872-7972pii
S0304394001015579journal_volume
300pub_type
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