Abstract:
:Molecular forms of butyrylcholinesterase (BuChE) were studied in microvessels isolated from rat brain, using sedimentation analysis in sucrose gradients. Three forms, G1, G2 and G4, were found with sedimentation coefficients close to 3S, 6S and 9S, respectively. The relative proportion of the 3 forms was 19% for the monomer, 33% for the dimer and 46% for the tetramer. This sedimentation pattern of BuChE forms appears to be characteristic of cerebral microvessels and may represent distinct functional features of the blood-brain barrier.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Catalán RE,Martínez AM,Aragonés MD,Hernández Fdoi
10.1016/0304-3940(90)90164-5subject
Has Abstractpub_date
1990-11-27 00:00:00pages
46-9issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(90)90164-5journal_volume
120pub_type
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