Molecular forms of butyrylcholinesterase in rat brain microvessels.

Abstract:

:Molecular forms of butyrylcholinesterase (BuChE) were studied in microvessels isolated from rat brain, using sedimentation analysis in sucrose gradients. Three forms, G1, G2 and G4, were found with sedimentation coefficients close to 3S, 6S and 9S, respectively. The relative proportion of the 3 forms was 19% for the monomer, 33% for the dimer and 46% for the tetramer. This sedimentation pattern of BuChE forms appears to be characteristic of cerebral microvessels and may represent distinct functional features of the blood-brain barrier.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Catalán RE,Martínez AM,Aragonés MD,Hernández F

doi

10.1016/0304-3940(90)90164-5

subject

Has Abstract

pub_date

1990-11-27 00:00:00

pages

46-9

issue

1

eissn

0304-3940

issn

1872-7972

pii

0304-3940(90)90164-5

journal_volume

120

pub_type

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