Pharmacological investigation on the role of dopamine in the rat locus coeruleus.

abstract：:The present study assessed the mechanisms by which nerve growth factor (NGF) increased the level of apolipoprotein E (apoE) in PC12 cells. NGF (50ng/mL) significantly increased apoE protein levels following 72h of treatment. Similarly NGF increased luciferase activity in cells transfected with a luciferase reporter co...

journal_title：Neuroscience letters

authors： Strachan-Whaley MR,Reilly K,Dobson J,Kalisch BE

更新日期：2015-05-19 00:00:00

abstract：:In complex regional pain syndrome (CRPS) many clinical symptoms suggest involvement of the central nervous system. Neuropathic pain as the leading symptom is often resistant to therapy. In the present study we investigated the analgesic efficiency of repetitive transcranial magnetic simulation (rTMS) applied to the mo...

journal_title：Neuroscience letters

authors： Pleger B,Janssen F,Schwenkreis P,Völker B,Maier C,Tegenthoff M

更新日期：2004-02-12 00:00:00

abstract：:We evaluated the neuroprotective effects of systemically administered magnesium against N-methyl-D-aspartate (NMDA)-mediated brain injury in perinatal rats. Postnatal day (PND) 7 rats received unilateral intrastriatal injections of 25 nmol NMDA followed 15 min later by single or multiple doses of magnesium intraperito...

journal_title：Neuroscience letters

authors： McDonald JW,Silverstein FS,Johnston MV

更新日期：1990-02-05 00:00:00

abstract：:The content of two neuropeptides, somatostatin (SRIF) and neuropeptide Y (NPY) has been determined in two cerebral cortical areas of Alzheimer's disease brain and in age-matched control brains. The content of SRIF-like immunoreactivity (SRIF-LI) was found to be decreased in Alzheimer temporal cortex (Brodmann area 21)...

journal_title：Neuroscience letters

authors： Dawbarn D,Rossor MN,Mountjoy CQ,Roth M,Emson PC

更新日期：1986-09-25 00:00:00

abstract：:The pharmacology of the metabotropic glutamate receptor (mGluR)-mediated potentiation of N-methyl-D-aspartate (NMDA)-evoked depolarisations in the CA1 region of rat hippocampal slices was investigated using an extracellular grease-gap method. The group I and II mGluR agonist (1S,3R)-1-aminocyclopentane-1,3-dicarboxyli...

journal_title：Neuroscience letters

authors： Fitzjohn SM,Irving AJ,Palmer MJ,Harvey J,Lodge D,Collingridge GL

更新日期：1996-01-26 00:00:00

abstract：:The effect of partial isomerization of dietary alpha-linolenic acid on the monoaminergic neurotransmitters in piglets was studied. After feeding the animals for 14 days with diets containing or not trans alpha-linolenic acid, neurotransmitters related to the monoaminergic function were quantified in the frontal cortex...

journal_title：Neuroscience letters

authors： Acar N,Chardigny JM,Berdeaux O,Almanza S,Sébédio JL

更新日期：2002-10-18 00:00:00

abstract：:Small-fiber neuropathy was induced in young adult mice by intraperitoneal injection of resiniferatoxin (RTX), a TRPV1 agonist. At day 7, RTX induced significant thermal and mechanical hypoalgesia. At day 28, mechanical and thermal nociception were restored. No nerve degeneration in skin was observed and unmyelinated n...

journal_title：Neuroscience letters

authors： Danigo A,Magy L,Richard L,Sturtz F,Funalot B,Demiot C

更新日期：2014-06-13 00:00:00

abstract：:Spinal cord injury (SCI) triggers pronounced inflammatory responses that are accompanied by neuronal disruption and functional deficits. SCI treatment remains an unmet clinical need. Emerging evidence suggests that riluzole may exert a neuroprotective effect due to its anti-inflammatory properties. However, details of...

journal_title：Neuroscience letters

authors： Wu Q,Zhang Y,Zhang Y,Zhang W,Zhang W,Liu Y,Xu S,Guan Y,Chen X

更新日期：2020-04-01 00:00:00

abstract：:Twelve human subjects performed a reciprocal precision aiming task of varying difficulty (index of difficulty=4, 5, or 6) while vision of the ongoing movement was available either continuously or intermittently. In the intermittent conditions, vision of the moving end-effector was available at regular intervals (equal...

journal_title：Neuroscience letters

authors： Bootsma RJ,Boulard M,Fernandez L,Mottet D

更新日期：2002-11-22 00:00:00

abstract：:Neurotrophins are a family of growth factor primarily acting in the nervous system, throughout two categories of membrane receptors on the basis of their high (Trk receptors) or low (p75NTR) affinity. Both neurotrophins and Trk receptors are phylogenetically conserved and are expressed not only in the central and peri...

journal_title：Neuroscience letters

authors： Abbate F,Guerrera MC,Montalbano G,Levanti MB,Germanà GP,Navarra M,Laurà R,Vega JA,Ciriaco E,Germanà A

更新日期：2014-03-20 00:00:00

abstract：:Conduction velocities of antidromically evoked impulses along the goldfish Mauthner axon were found to be inversely correlated with body length. To test the hypothesis that such a relation is accompanied by a reduction in axonal diameter with increasing fish size, Mauthner axon diameters were measured. A parabolic rel...

journal_title：Neuroscience letters

authors： Funch PG,Kinsman SL,Faber DS,Koenig E,Zottoli SJ

更新日期：1981-12-11 00:00:00

abstract：:This study analyses the finger force sharing using power grip task with adapted experimental conditions. This paradigm limits as much as possible the external constraints when the Index (I), Middle (M), Ring (R) and Little (L) fingers act simultaneously: the thumb did not oppose the other fingers and no secondary mome...

journal_title：Neuroscience letters

authors： Vigouroux L,Rossi J,Foissac M,Grélot L,Berton E

更新日期：2011-10-31 00:00:00

abstract：:The electron microscopic findings in cats after complete interruption of all afferents to caudate nucleus as well as of its efferent fibers, suggest that the type IX synapses, the presynaptic component of which contains large empty round vesicles, are formed by the axon terminals of intrinsic neurons. They make synapt...

journal_title：Neuroscience letters

authors： Hassler R,Chung JW,Wagner A,Rinne U

更新日期：1977-07-01 00:00:00

abstract：:Previous studies have shown that the midbrain periaqueductal gray (PAG) projects to the ventrolateral medulla (VLM). Here, we studied PAG projections to the area of A1/C1 neurons in the VLM in the rat using phaseolus vulgaris leucoagglutinin (PHA-L) anterograde tracing combined with immunocytochemistry for tyrosine hy...

journal_title：Neuroscience letters

authors： Chen S,Aston-Jones G

更新日期：1995-08-04 00:00:00

abstract：:The effect of dopamine on the 3',5'-cyclic adenosine monophosphate (cAMP) generating system of membrane particles of rat prostate gland was studied. Dopamine increased the concentration of cAMP in a dose-dependent manner. The selective D1 receptor inhibitor SCH 23390 caused a decrease in dopamine-elicited cAMP levels....

journal_title：Neuroscience letters

authors： Amenta D,Cavallotti C,Amenta F

更新日期：1987-06-01 00:00:00

abstract：:Classical theories on absence epilepsy suggest that spike-wave discharge (SWDs) represent thalamo-cortical oscillations, where an abnormally excitable cortex interacts with thalamus and brain stem reticular formation. The limbic system is generally not included in any theory about the pathogenesis of absence seizures....

journal_title：Neuroscience letters

authors： Tolmacheva EA,van Luijtelaar G

更新日期：2007-04-06 00:00:00

abstract：:The intergeniculate leaflet (IGL) of the lateral geniculate complex is marked by the presence of neuro-peptide Y-containing neurons that project to the suprachiasmatic nuclei (SCN) of the hypothalamus. In the present study, we demonstrate that both the IGL and SCN in the hamster and rat are specifically delineated by ...

journal_title：Neuroscience letters

authors： Morin LP,Johnson RF,Moore RY

更新日期：1989-04-24 00:00:00

abstract：:Attention-deficit/hyperactivity disorder (ADHD) is highly prevalent in children and adolescents and both environmental and genetic factors play major roles. Polyunsaturated fatty acids (PUFAs) are postulated to contribute to the development of the infant brain and an imbalance in these may increase the risk of ADHD. I...

journal_title：Neuroscience letters

authors： Bartl J,Walitza S,Grünblatt E

更新日期：2014-01-24 00:00:00

abstract：:The study of neural arousal mechanisms has been greatly aided by the discovery of the orexin peptides (orexin A and orexin B), the subsequent identification of the neurons that synthesize these peptides, their projections in the brain, and the distribution of orexin receptors in the central nervous system. Orexin neur...

journal_title：Neuroscience letters

authors： Brown TM,Coogan AN,Cutler DJ,Hughes AT,Piggins HD

更新日期：2008-12-31 00:00:00

abstract：:Social isolation has been widely described to induce compulsive aggressive behavior and produce a large decrease of brain serotonin turnover in male mice. The aggressiveness by isolation in mice has been often used as a means for a better understanding of disturbed behavior in human beings. We found that male ICR whit...

journal_title：Neuroscience letters

authors： Miyachi Y,Kasai H,Ohyama H,Yamada T

更新日期：1994-07-04 00:00:00

abstract：:We studied whether eugenol provides neuroprotection against delayed neuronal death in the hippocampal CA1 region following a 5 min occlusion of the common carotid arteries bilaterally under either free-regulating temperature (TF) or maintained temperature (TM, 37 degrees C) conditions in gerbils. Right after occlusion...

journal_title：Neuroscience letters

authors： Won MH,Lee JC,Kim YH,Song DK,Suh HW,Oh YS,Kim JH,Shin TK,Lee YJ,Wie MB

更新日期：1998-09-25 00:00:00

abstract：:Prefoldin is a molecular chaperone that assists the folding of newly synthesized polypeptide chains and prevents aggregation of misfolded proteins. Dysfunction of prefoldin is one of the causes of neurodegenerative diseases such as Alzheimer's disease. The aim of this study was to clarify the involvement of prefoldin ...

journal_title：Neuroscience letters

authors： Kadoyama K,Matsuura K,Takano M,Maekura K,Inoue Y,Matsuyama S

更新日期：2019-11-01 00:00:00

abstract：:This study examined the effects of anterior pretectal nucleus (APT) conditioning stimulation on the activity of 92 functionally identified somatosensory brainstem neurons in the trigeminal (V) subnuclei oralis, interpolaris and caudalis of anesthetized rats. Conditioning stimulation inhibited most of the nociceptive n...

journal_title：Neuroscience letters

authors： Chiang CY,Chen IC,Dostrovsky JO,Sessle BJ

更新日期：1992-01-06 00:00:00

abstract：:Associations between PIN1 gene polymorphisms and Alzheimer's disease (AD) risk remain controversial, possibly because single studies often lack sufficient statistical power. In this study, we performed a meta-analysis to evaluate the association of two commonly studied PIN1 polymorphisms, -842G/C and -667T/C, with the...

journal_title：Neuroscience letters

authors： Cao L,Wang F,Ge H,Wu PC,Qu P,Chen GH,Gao ZL

更新日期：2013-02-22 00:00:00

abstract：:Perception of limb position and motion is abnormal in Parkinson's disease (PD). Despite the fact that the processing of proprioceptive inputs is inherently temporal, most studies have assessed spatial aspects of proprioception in PD patients. Here, we use a recently described method to test whether deficits also exist...

journal_title：Neuroscience letters

authors： Fiorio M,Stanzani C,Rothwell JC,Bhatia KP,Moretto G,Fiaschi A,Tinazzi M

更新日期：2007-05-07 00:00:00

abstract：:The diagonal band of Broca (DBB) is involved in cardiovascular control in rats. In the present study, we report the effect of acute and reversible neurotransmission inhibition in the DBB by bilateral microinjection of the nonselective neurotransmission blocker CoCl(2) (1mM, 100 nL) on the cardiac baroreflex response i...

journal_title：Neuroscience letters

authors： Crestani CC,Tavares RF,Alves FH,Resstel LB,Corrêa FM

更新日期：2008-12-26 00:00:00

abstract：:The opioid peptide dynorphin decreased somatic calcium-dependent action potential duration in a portion of mouse dorsal root ganglion (DRG) neurons without altering resting membrane potential or conductance. Dynorphin action was antagonized by naloxone. Responses of DRG neurons to dynorphin differed from responses to ...

journal_title：Neuroscience letters

authors： Werz MA,Macdonald RL

更新日期：1984-05-04 00:00:00

abstract：:To investigate the capacity of the central nervous system to integrate and differentiate two different muscular fatigue states, the present study examines the changes on multi-joint movement organization following muscular fatigue of elbow extensor muscles (triceps brachii) induced by voluntary versus electrically ind...

journal_title：Neuroscience letters

authors： Huffenus AF,Forestier N

更新日期：2006-07-31 00:00:00

abstract：:Older adults have difficulties in binding information in long-term memory (e.g. objects with colours). The effect of age on visual short-term memory (VSTM) binding is less well understood. Recent evidence has suggested that older adults' VSTM for colours bound to shapes or for locations bound in configural representat...

journal_title：Neuroscience letters

authors： Parra MA,Abrahams S,Logie RH,Sala SD

更新日期：2009-01-02 00:00:00

abstract：:In recent years, animal behavioral models, particularly those used in pain research, have been increasingly scrutinized and criticized for their role in the poor translation of novel pharmacotherapies for chronic pain. This article addresses the use of animal models of pain from the perspective of industrial drug disc...

journal_title：Neuroscience letters

authors： Whiteside GT,Pomonis JD,Kennedy JD

更新日期：2013-12-17 00:00:00