Abstract：
:Social isolation has been widely described to induce compulsive aggressive behavior and produce a large decrease of brain serotonin turnover in male mice. The aggressiveness by isolation in mice has been often used as a means for a better understanding of disturbed behavior in human beings. We found that male ICR white Swiss mice exhibiting isolation-induced aggression became gradually calm and showed remarkably quiet behavior 7 to 10 days after whole body irradiation of very low-dose X-rays (5-15 cGy). Higher doses (25-35 cGy), however, could not induce such effects. We also obtained the data on brain biochemistry giving a further support for the above low-dose effects on the mouse behavior. Brain serotonin turnover which has been known to be related to aggressive behavior in 5 or 15 cGy irradiated mice was faster than in aggressive control animals.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Miyachi Y,Kasai H,Ohyama H,Yamada Tdoi
10.1016/0304-3940(94)91086-3subject
Has Abstractpub_date
1994-07-04 00:00:00pages
92-4issue
1-2eissn
0304-3940issn
1872-7972pii
0304-3940(94)91086-3journal_volume
175pub_type
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journal_title：Neuroscience letters
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doi：10.1016/0304-3940(83)90052-6
更新日期：1983-10-10 00:00:00
abstract：:Although metabolic syndrome (MS) is recognized as a risk factor for ischemic stroke, little is known about genetic variants that confer susceptibility to ischemic stroke among individuals with or without MS. This study was completed to investigate whether the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorp...
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更新日期：2009-05-15 00:00:00
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journal_title：Neuroscience letters
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doi：10.1016/j.neulet.2012.06.048
更新日期：2012-08-08 00:00:00
abstract：:In anorexia nervosa patients, body image distortion is a core and often persistent symptom, which continues to pose a risk for relapse even after weight recovery. Using functional magnetic resonance imaging (fMRI) in combination with a computer-based life image distortion technique, we stimulated female anorectic pati...
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doi：10.1016/s0304-3940(02)00312-9
更新日期：2002-06-21 00:00:00
abstract：:Astrocyte cell cultures were established from human fetal brains and exposed to human recombinant tumor necrosis factor alpha (TNF alpha) and human recombinant interferon gamma (IFN gamma), and the proliferative response was assessed by bromodeoxyuridine-immunostaining technique. TNF alpha showed an inhibitory activit...
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doi：10.1016/0304-3940(93)90034-i
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2007.09.055
更新日期：2007-12-11 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：1995-10-27 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(03)00007-7
更新日期：2003-04-17 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(97)00913-0
更新日期：1997-12-19 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(89)90504-1
更新日期：1989-03-27 00:00:00
abstract：:Those with high baseline stress levels are more likely to develop mild cognitive impairment (MCI) and Alzheimer's Disease (AD). While meditation may reduce stress and alter the hippocampus and default mode network (DMN), little is known about its impact in these populations. Our objective was to conduct a "proof of co...
journal_title：Neuroscience letters
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.neulet.2013.10.001
更新日期：2013-11-27 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2012.04.065
更新日期：2012-06-19 00:00:00
abstract：:The neuroprotective activity of riluzole has been studied on N-methyl-D-aspartate (NMDA)- or veratridine-induced toxicity in immature rat hippocampal slices. Neurodegeneration was assessed by the measurement of LDH release and histology. Veratridine-induced LDH release can be inhibited by 100 microM riluzole (-90% and...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(94)90053-1
更新日期：1994-08-15 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2006.12.058
更新日期：2007-03-13 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(94)11788-k
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(92)90229-z
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(80)90177-9
更新日期：1980-12-01 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2004.04.011
更新日期：2004-06-17 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：2005-10-07 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：1998-02-27 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：2001-02-16 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
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更新日期：2005-10-14 00:00:00
abstract：:The atypical serine/threonine protein kinase, a mammalian target of rapamycin (mTOR), is believed to be essential to the regulation of cell growth and the functions of the central nervous system. By using calcium imaging and patch-clamping techniques to study the role of this signaling pathway in the activity of cultu...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.06.006
更新日期：2008-08-15 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(97)00827-6
更新日期：1997-11-21 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2016.08.012
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2004.03.051
更新日期：2004-06-03 00:00:00
abstract：:N-Acetylaspartylglutamate (NAAG) is a dipeptide, and has been demonstrated to be a putative neurotransmitter in the brain. We hereby report the toxicity of NAAG in sagittal slices of mouse brain, in vitro, which is prevented by both N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists. Incubation of mouse bra...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90368-4
更新日期：1991-05-13 00:00:00
abstract：:The aim of the present experiment was to study how hypnotic susceptibility and hypnosis affect motoneuron excitability. In a first trial, human subjects were selected according to their hypnotic susceptibility. In a second trial, the Hoffmann (H) reflex amplitude of the soleus muscle was studied in 3 groups: (1) highl...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(89)90347-9
更新日期：1989-09-25 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2003.09.020
更新日期：2004-01-02 00:00:00
