Abstract：
:The aim of the study was to evaluate the role of steady-state and dynamic visual gestures of vowels in stuttering inhibition. Eight adults who stuttered recited sentences from memory while watching video presentations of the following visual speech gestures: (a) a steady-state /u/, (b) dynamic production of /a-i-u/, (c) steady-state /u/ with an accompanying audible 1 kHz pure tone, and (d) dynamic production of /a-i-u/ with an accompanying audible 1 kHz pure tone. A 1 kHz pure tone and a no-external signal condition served as control conditions. Results revealed a significant main effect of auditory condition on stuttering frequency. Relative to the no-external signal condition, the combined visual plus pure tone conditions resulted in a statistically significant reduction in stuttering frequency. In addition, a significant difference in stuttering frequency was also observed when the visual plus pure tone conditions were compared to the visual only conditions. However, no significant differences were observed between the no-external signal condition and visual only conditions, or the no-external signal condition and pure tone condition. These findings are in contrast to previous findings demonstrated by similar vowel gestures presented via the auditory modality that resulted in high levels of stuttering inhibition. The differential role of sensory modalities in speech perception and production as well as their individual capacities to transfer gestural information for the purposes of stuttering inhibition is discussed.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Guntupalli VK,Nanjundeswaran C,Kalinowski J,Dayalu VNdoi
10.1016/j.neulet.2011.01.049subject
Has Abstractpub_date
2011-03-29 00:00:00pages
39-42issue
1eissn
0304-3940issn
1872-7972pii
S0304-3940(11)00095-4journal_volume
492pub_type
杂志文章abstract：:We have studied electrophysiologically the actions of gamma-aminobutyric acid (GABA) and related pharmacological agents on fish retinal horizontal cells by recording intracellularly from isolated retinae perfused with Ringer containing the various drugs. We show that although GABA usually hyperpolarizes the membrane p...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(84)90211-8
更新日期：1984-01-27 00:00:00
abstract：:During and after degeneration of the optic nerve afferents in the rat suprachiasmatic nucleus (SCN) postsynaptic density (PD) material is added to existing symmetrical and asymmetrical appositions of non-optic synapses on optic target neurons. If the correlation between thickness of the postsynaptic density and excita...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(80)90056-7
更新日期：1980-04-01 00:00:00
abstract：:Following unilateral electrolytic lesioning of the rat entorhinal cortex, we assessed changes in messenger RNA (mRNA) levels for four neuron-associated proteins, GAP-43, SCG10, 68 kDa neurofilament (NF68), and alpha 1-tubulin that encode proteins of importance to synaptic remodelling. The mRNA levels for GAP-43 and SC...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(94)11231-7
更新日期：1995-02-09 00:00:00
abstract：:The angular distribution of mitotic spindle fibers has been studied in the telencephalic ventricular zone (VZ) of mouse embryos and has been found to be monophasic and invariant during the early cortical histogenesis both in the normal and in a reeler embryo. This observation suggests that the orientation of mitotic s...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(79)90077-6
更新日期：1979-06-01 00:00:00
abstract：:Elongation factor-2 kinase (eEF-2K) is a Ca(2+)/calmodulin-dependent protein kinase that is highly specific for eukaryotic elongation factor-2. In the present study, we examined the developmental expression of eEF-2K messenger RNA (mRNA) in the mouse brain. At E13, the expression of eEF-2K mRNA is already evident in b...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(02)00715-2
更新日期：2002-09-13 00:00:00
abstract：:GABAergic modulation of enkephalin, substance P and glutamic acid decarboxylase (GAD67) gene expression and the alterations induced by dopamine receptor blockade were studied in the rat striatum. Following subchronic treatment with the GABA-A agonist muscimol, the GABA-B agonist baclofen or the GABA transaminase inhib...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(94)90537-1
更新日期：1994-10-24 00:00:00
abstract：:Previous studies have shown an association between diabetes mellitus and impairments in learning and memory. These deficits were partially reversed by the use of insulin. Due to the fact that exercise has positive effects on many physiological systems, including the central nervous system, the present study, evaluated...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2009.03.052
更新日期：2009-05-15 00:00:00
abstract：:This review attempts to explain the symptoms experienced by patients with inflammatory neuropathies by pathophysiological events. The emphasis is not on the primary events that may cause a particular illness but on downstream events taking place in peripheral nerves or muscles. Symptoms that will be discussed include ...
journal_title：Neuroscience letters
pub_type： 杂志文章,评审
doi：10.1016/j.neulet.2014.12.009
更新日期：2015-06-02 00:00:00
abstract：:Rapid removal of synaptically released glutamate from the extracellular space ensures a high signal-to-noise ratio in excitatory neurotransmission. In the cerebellum, glial glutamate transporters, GLAST and GLT-1, are co-localized in the processes of Bergmann glia wrapping excitatory synapses on Purkinje cells (PCs). ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2007.04.062
更新日期：2007-06-08 00:00:00
abstract：:The in vivo effects of the alpha 2-adrenoceptor idazoxan, rauwolscine and phentolamine on alpha 2-auto/heteroreceptors and 5-HT1A autoreceptors modulating the synthesis of dopa/noradrenaline and 5-HTP/serotonin were assessed in rats, using the accumulation of dopa and 5-HTP after decarboxylase inhibition as a measure ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(96)13132-3
更新日期：1996-11-01 00:00:00
abstract：:There have been reports of regional differences in the activation of mitogen activated protein kinases (MAPKs) and in the induction of immediate early genes after electroconvulsive shock (ECS) in the rat brain. This study was performed to determine whether ECS induce the region-specific phosphorylation of MAPK-downstr...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(02)00568-2
更新日期：2002-08-23 00:00:00
abstract：:The ability to extract invariant relationships from physically varying stimulation is critical for example to categorical perception of complex auditory information such as speech and music. Human subjects were presented with tone pairs randomly varying over a wide frequency range, there being no physically constant t...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(99)00237-2
更新日期：1999-04-23 00:00:00
abstract：:Intracellular recording techniques were used to monitor the evoked responses in hippocampal CA1 pyramidal cells following focal stimulation of the proximally and distally located apical dendritic synapses. The local anaesthetic, QX-314, when injected into individual cells, caused a complete time-dependent blockade of ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(94)90665-3
更新日期：1994-05-19 00:00:00
abstract：:Exposure to a single session of intense inescapable stressors results in elevations of plasma corticosterone levels selective to the trough of the circadian rhythm that last for several days after stressor cessation. In the present study, we examined whether this stress-induced alteration in the regulation of the circ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2004.10.016
更新日期：2005-02-01 00:00:00
abstract：:Successful transplantations have been made of cultured explants of human fetal spinal cord into surgically created cavities in the motor cortical area of non-immunosuppressed young adult rats. The cultured cells were marked by brief incubation with Phaseolus vulgaris leucoagglutinin (PHA) just prior to transplantation...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(87)90709-9
更新日期：1987-05-06 00:00:00
abstract：:We have investigated the effect of histamine (HA) on spontaneous firing of dopaminergic (DA) and GABAergic neurons in the substantia nigra (SN) and the ventral tegmental area (VTA) of the rat in vitro. Single-unit extracellular recordings were obtained and drugs were bath applied. In both regions application of HA (10...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(02)00050-2
更新日期：2002-03-08 00:00:00
abstract：:Protein misfolding cyclic amplification (PMCA) is a highly sensitive technique used to detect minute amounts of scrapie prion protein (PrP(Sc)), a major protein component of the infectious agents associated with prion diseases. Although exponential in vitro amplification of hamster scrapie PrP(Sc) has been established...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2006.11.056
更新日期：2007-02-21 00:00:00
abstract：:By in situ hybridization, we show the ability of human neuroblastoma SY 5Y cells to synthesize apolipoprotein E (apoE) mRNA. This synthesis varied during cell NGF-differentiation: the mRNA level decreased during the first 4 days of NGF treatment (NGF 4 days) and then increased during the 3 following days (NGF 7 days)....
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(99)00167-6
更新日期：1999-04-16 00:00:00
abstract：:Intracortical facilitatory and inhibitory processes in the primary motor cortex (M1) play an important role in both the preparation and execution of motor tasks. Here we aimed to (1) confirm the existence of, and further characterise, intracortical facilitation at long conditioning-test stimulus intervals at subthresh...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2014.03.060
更新日期：2014-06-06 00:00:00
abstract：:In order to describe how high altitude affects the body during a one night stay at 4000m experiments were performed in a hypobaric chamber and compared to a study on Dachstein (mountain in Austria, 2700m). Ten subjects had to perform a reaction time task at different altitudes. The EEG and ECG were recorded simultaneo...
journal_title：Neuroscience letters
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.neulet.2008.06.075
更新日期：2008-09-12 00:00:00
abstract：:The present study assessed the mechanisms by which nerve growth factor (NGF) increased the level of apolipoprotein E (apoE) in PC12 cells. NGF (50ng/mL) significantly increased apoE protein levels following 72h of treatment. Similarly NGF increased luciferase activity in cells transfected with a luciferase reporter co...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2015.03.032
更新日期：2015-05-19 00:00:00
abstract：:Enterovirus infections of the central nervous system (CNS) are common and important causes of morbidity in immunocompromised children and adults. In this study we identify and characterize coxsackievirus B4-induced neuronal death. To investigate the CNS pathophysiology resulting from this viral infection, cultured rat...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(02)00340-3
更新日期：2002-07-05 00:00:00
abstract：:In the present study we have investigated the effects of nicotine, capsaicin, potassium, glutamate and aspartate on release of calcitonin gene-related peptide (CGRP)-like immunoreactivity (-LI) from guinea-pig dorsal root ganglion (DRG) cultures. In addition the possible influence of Ruthenium red (RR), neuropeptide Y...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(92)90301-m
更新日期：1992-03-16 00:00:00
abstract：:The time course of the event related potentials evoked within a delayed matching to sample task employing verbal and pictorial stimuli was analyzed with a source reconstruction method (minimum norm method). During signal stimulus presentation pictorial stimuli evoked more activity than verbal stimuli. Activity was par...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(98)00637-5
更新日期：1998-09-11 00:00:00
abstract：:CaCl2-induced myelopathy was produced in rats by the application of a solution of CaCl2 to exposed leptomeninges of lumbosacral spinal cord. Equal lengths of remote cervical and lumbar cord were removed at intervals following Ca2+ application. The total Ca2+ in tissue from lumbar cord was significantly elevated over a...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(84)90302-1
更新日期：1984-08-31 00:00:00
abstract：:Recently developed neuroanatomical staining methods utilizing transportable markers have made it possible to visualize individual, growing retinotectal axons in the chick embryo. In the present work, we used such methods to examine the behavior of mechanically deflected axons on the tectum. The deflection of axons was...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(86)90613-0
更新日期：1986-12-03 00:00:00
abstract：:This experiment was designed to simulate experimentally the specific parameters of geomagnetic activity that evoke epileptic seizures. The numbers of overt limbic seizures (rearing, paroxysmal forelimb clonus and falling) in a population of epileptic rats were recorded nightly for 65 successive days between 0200 and 0...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(97)13446-2
更新日期：1997-03-07 00:00:00
abstract：:A modified "cross-modal delayed response" paradigm was used to investigate putative processing of face expression in the absence of focused attention to the face. Neutral, happy and sad faces were presented during intervals occurring between a tone and a response imperative signal (a faint click), while subjects were ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2006.09.081
更新日期：2006-12-20 00:00:00
abstract：:Kainic acid binding was measured in crude membrane fractions prepared from postmortem human caudate tissue of control persons and patients afflicted with Huntington's disease. A significant reduction in binding sites with no change in affinity was found in the Huntington's tissue, the apparent dissociation constants (...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(79)96156-1
更新日期：1979-10-01 00:00:00
abstract：:The pattern of projection of the ventrobasal thalamic complex (VB) upon the neocortical barrel field of normal and reeler mutant mice was determined by orthograde degeneration experiments and by Timm's histochemical method. In both reeler and normal mice the thalamic terminals are concentrated at the midcortical zone ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(76)90091-4
更新日期：1976-09-01 00:00:00
