Abstract：
:Successful transplantations have been made of cultured explants of human fetal spinal cord into surgically created cavities in the motor cortical area of non-immunosuppressed young adult rats. The cultured cells were marked by brief incubation with Phaseolus vulgaris leucoagglutinin (PHA) just prior to transplantation. Following sacrifice of the rats 1.5 months later, PHA immunohistochemistry clearly outlined the demarcation zone of the explants. The transplanted neurons possessed long, somewhat tortuous fibers with occasional varicosities, as well as some thick processes. These findings extend our previous studies in which it was shown that cultured human fetal adrenal medulla and sympathetic ganglia cells could be successfully transplanted to non-immunosuppressed rat brain. They also suggest that PHA may be a valuable marker for transplanted cells at least for 1.5 months post-transplantation.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Kamo H,Kim SU,McGeer PL,Araki M,Tomimoto H,Kimura Hdoi
10.1016/0304-3940(87)90709-9subject
Has Abstractpub_date
1987-05-06 00:00:00pages
163-7issue
2eissn
0304-3940issn
1872-7972pii
0304-3940(87)90709-9journal_volume
76pub_type
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journal_title：Neuroscience letters
pub_type： 杂志文章
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