GYKI 52466 antagonizes glutamate responses but not NMDA and kainate responses in rat abducens motoneurones.

abstract：:Previous studies have shown that striatum and nucleus accumbens (NAc) are two different structures in mediating addictive drug-induced ascorbic acid (AA) release. In order to further characterize the different effects of drugs-induced AA release in the striatum and NAc, in the present study, we investigated the effect...

journal_title：Neuroscience letters

authors： Gu PF,Wu CF,Yang JY,Shang Y,Hou Y,Bi XL,Dai F

更新日期：2006-05-15 00:00:00

abstract：:Following peripheral nerve section, the cell body and proximal axon undergo various physiological and morphological changes which may be associated with regrowth. We found that axotomy reduced the amplitude and duration of the afterhyperpolarization (AHP) of the action potential (AP) of bullfrog sympathetic neurones. ...

journal_title：Neuroscience letters

authors： Kelly ME,Gordon T,Shapiro J,Smith PA

更新日期：1986-06-18 00:00:00

abstract：:We investigated laminin beta1 expression in the hippocampi of patients with intractable epilepsy and explored the role of laminin beta1 in the pathogenesis of this condition. Fluorescence quantitative PCR, immunofluorescence, immunohistochemistry and Western blotting were used to measure laminin beta1 expression in su...

journal_title：Neuroscience letters

authors： Wu Y,Wang XF,Mo XA,Sun HB,Li JM,Zeng Y,Lin T,Yuan J,Xi ZQ,Zhu X,Zheng JO

更新日期：2008-10-10 00:00:00

abstract：:This study was aimed to determine the effect of unilateral hippocampal inactivation on spatial memory retrieval in male and female Wistar rats. Subjects were chronically implanted with a stainless-steel cannula that enabled unilateral intrahippocampal injections of tetrodotoxin, a sodium channel blocker. Rats were tra...

journal_title：Neuroscience letters

authors： Cimadevilla JM,Arias JL

更新日期：2008-07-04 00:00:00

abstract：:The somatosensory projection to the striatum of the rat was investigated by electrophysiological mapping. Fifty-five units were encountered that responded to specific forms of stimulation delivered to particular parts of the body. Units that responded to stimuli delivered to the hindlimb, scrotum and tail were found i...

journal_title：Neuroscience letters

authors： Richards CD,Taylor DC

更新日期：1982-06-30 00:00:00

abstract：:In the course of our survey of natural compounds inhibiting prostaglandin E2 release and/or lipopolysaccharide (LPS)-induced transcriptional stimulation via NF-kappaB, a central regulator of inflammatory genes, from natural resources, we found garcinone B, a xanthone from callus tissue culture of Hypericum patulum, as...

journal_title：Neuroscience letters

authors： Yamakuni T,Aoki K,Nakatani K,Kondo N,Oku H,Ishiguro K,Ohizumi Y

更新日期：2006-02-20 00:00:00

abstract：:This event-related functional Magnetic Resonance Imaging study examined the differential neural activities associated with a Risky-Gains task in 18 healthy individuals of high (n=9) or low (n=9) impulsiveness, according to their scores on the Barratt Impulsiveness Scale (BIS). The neural activities of people belonging...

journal_title：Neuroscience letters

authors： Lee TM,Chan CC,Han SH,Leung AW,Fox PT,Gao JH

更新日期：2008-06-20 00:00:00

abstract：:Prominent accounts of decision making state that decisions are made on the basis of an accumulation of sensory evidence, orchestrated by networks of prefrontal and parietal neural populations. Here we assess whether these findings generalize to decisions on self-motion. Participants were presented with whole body yaw ...

journal_title：Neuroscience letters

authors： de Winkel KN,Nesti A,Ayaz H,Bülthoff HH

更新日期：2017-07-27 00:00:00

abstract：:The volume density of mast cells was estimated in nerve end neuromas at various time-points after transection of the left sciatic nerve of 6-week-old mice. After an initial reduction in the amount of mast cells there was a steady increase with numerous cells in 6-month-old neuromas. The variation in amount of mast cel...

journal_title：Neuroscience letters

authors： Nennesmo I,Reinholt F

更新日期：1986-09-12 00:00:00

abstract：:Excessive activation of the N-methyl-D-aspartate (NMDA) receptor-channel complex has been implicated as one of the mechanisms by which ischemia-induced neuronal damage is mediated. Elevated glycine levels during ischemia may contribute to damage mediated by the NMDA receptor as glycine binding potentiates NMDA respons...

journal_title：Neuroscience letters

authors： Wood ER,Bussey TJ,Phillips AG

更新日期：1992-09-28 00:00:00

abstract：:Whale brains have attracted the attention of neuroscientists but there are only sparse studies on whale glial cells. Here we report on immunolabeling of astrocytes by antibodies to glial fibrillary acidic protein (GFAP) or protein S-100 beta (both by the streptavidin/biotin technique), and labeling of microglial cells...

journal_title：Neuroscience letters

authors： Pritz-Hohmeier S,Härtig W,Behrmann G,Reichenbach A

更新日期：1994-02-14 00:00:00

abstract：:Whether or not chronic L-dopa treatment (100 mg/kg, intraperitoneally (i.p.), twice daily for 4 weeks) alters lipid peroxidation in the brain as an indicator of neuronal damage was examined in normal mice and mice in which catecholamine (CA) neurons had been injured previously by the administration of 6-hydroxydopamin...

journal_title：Neuroscience letters

authors： Ogawa N,Asanuma M,Kondo Y,Kawada Y,Yamamoto M,Mori A

更新日期：1994-04-25 00:00:00

abstract：:Cannabinoid CB1 receptor (CB1R) is highly expressed in the mesocorticolimbic system and associated with drug craving and relapse. Clinical trials suggest that CB1R antagonists may represent new therapies for drug addiction. However, the downstream signaling of CB1R is not fully elucidated. In the present study, we inv...

journal_title：Neuroscience letters

authors： Zhang J,Wang N,Chen B,Wang Y,He J,Cai X,Zhang H,Wei S,Li S

更新日期：2016-09-06 00:00:00

abstract：:Current theories of orbitofrontal cortex (OFC) function suggest that this region should participate in the generation of error-related signals associated with the outcomes of actions. We investigated the impact of lesions to OFC on the error-related negativity (ERN), an electrophysiological marker of performance monit...

journal_title：Neuroscience letters

authors： Turken AU,Swick D

更新日期：2008-08-15 00:00:00

abstract：:In an attempt to examine a possible relationship between heat shock stress and an induction of amyloid precursor protein, cultured lymphoblastoid cells established from 12 human subjects were treated with heat shock at 42 degrees C for 30 min. The levels of mRNA for amyloid precursor protein (APP), heat shock protein ...

journal_title：Neuroscience letters

authors： Abe K,St George-Hyslop PH,Tanzi RE,Kogure K

更新日期：1991-04-29 00:00:00

abstract：:The FE65 protein was previously described interacting with amyloid protein precursor (APP) and mediating its internalization. Hu et al. (Hum. Genet., 103 (1998) 295) recently reported that a deletion polymorphism in intron 13 of the FE65 gene may be protective for sporadic Alzheimer's disease (AD) forms and suggested ...

journal_title：Neuroscience letters

authors： Lambert JC,Mann D,Goumidi L,Harris J,Pasquier F,Frigard B,Cottel D,Lendon C,Iwatsubo T,Amouyel P,Chartier-Harlin MC

更新日期：2000-10-20 00:00:00

abstract：:Differential performance over a wide range of possible postural coordination modes was investigated using 16 ankle-hip relative phase patterns from 0 degrees to 337.5 degrees. Participants were instructed to produce each coordination mode with and without real time visual feedback. Feedback consisted of a Lissajous fi...

journal_title：Neuroscience letters

authors： Faugloire E,Bardy BG,Merhi O,Stoffregen TA

更新日期：2005-02-10 00:00:00

abstract：:In anorexia nervosa patients, body image distortion is a core and often persistent symptom, which continues to pose a risk for relapse even after weight recovery. Using functional magnetic resonance imaging (fMRI) in combination with a computer-based life image distortion technique, we stimulated female anorectic pati...

journal_title：Neuroscience letters

authors： Seeger G,Braus DF,Ruf M,Goldberger U,Schmidt MH

更新日期：2002-06-21 00:00:00

abstract：:Peptide histidine-isoleucine (PHI) immunoreactivity was located in amacrine-like cells in adult rat retina by use of immunohistochemical techniques. Immunoreactive somata were found in the proximal part of the inner nuclear layer. From these somata, processes could be followed into the inner plexiform layer. The termi...

journal_title：Neuroscience letters

authors： Mikkelsen JD,Larsen JN,Fahrenkrug J,Møller M

更新日期：1987-08-31 00:00:00

abstract：:The irreversible opiate antagonists beta-funaltrexamine (beta-FNA) and beta-chlornaltrexamine (beta-CNA) were injected into rat striatum. One day later, mu-opioid receptor binding, as assessed by receptor autoradiography, was abolished in the injected striatum, while [3H]spiperone binding remained largely unaffected. ...

journal_title：Neuroscience letters

authors： Morris BJ,Höllt V,Herz A

更新日期：1988-06-17 00:00:00

abstract：:A random sample of 60 late-onset Alzheimer's disease (AD) cases from a population-based study were apolipoprotein E (apoE) genotyped and clinically examined with a 3-year interval. The epsilon 4 allele carriers had a significantly lower age of disease onset compared to non-epsilon 4 carriers. However, no significant d...

journal_title：Neuroscience letters

authors： Basun H,Grut M,Winblad B,Lannfelt L

更新日期：1995-01-02 00:00:00

abstract：:Stress increases associative learning and the density of dendritic spines in the hippocampus of male rats. In contrast, exposure to the same stressor impairs associative learning and reduces spine density in females. These effects in females are most evident when they are in the proestrus phase of the estrous cycle. A...

journal_title：Neuroscience letters

authors： Dalla C,Whetstone AS,Hodes GE,Shors TJ

更新日期：2009-01-02 00:00:00

abstract：:The cells of the entorhinal cortex receive a dense innervation of serotonergic fibres from the Raphe nuclei and express a high density of 5-hydroxytryptamine 1A (5-HT1A) receptors. We investigated the effects of serotonin on excitatory synaptic transmission in principal cells from entorhinal cortex layers II and III w...

journal_title：Neuroscience letters

authors： Schmitz D,Empson RM,Gloveli T,Heinemann U

更新日期：1995-04-28 00:00:00

abstract：:Chewing and walking are two oscillatory behaviors performed on an everyday basis. The current study examined the impact chewing at different speeds (i.e. fast, slow, preferred) had on walking performance for fifteen young healthy adults (23.2 + 4.2 years) and fifteen healthy older participants (66.5 + 3.2 years). Chew...

journal_title：Neuroscience letters

authors： Samulski B,Prebor J,Armitano C,Morrison S

更新日期：2019-04-17 00:00:00

abstract：:The effect of pineal indoles on fast axoplasmic transport of proteins in the sciatic nerve was examined in rats injected with [3H]leucine in the sixth lumbar dorsal root ganglion. Melatonin (350-1100 nmol) applied locally in the sciatic nerve impaired significantly axonal transport. At a 350-nmol dose all other indole...

journal_title：Neuroscience letters

authors： Prevedello MR,Ritta MN,Cardinali DP

更新日期：1979-06-01 00:00:00

abstract：:To examine whether the Haken-Kelso-Bunz model for rhythmic interlimb coordination applies to walking side-by-side on a treadmill, we invited six pairs of participants to coordinate their stepping movements at seven prescribed relative phases (between 0 degrees and 180 degrees ) to scan the attractor layout governing t...

journal_title：Neuroscience letters

authors： van Ulzen NR,Lamoth CJ,Daffertshofer A,Semin GR,Beek PJ

更新日期：2010-04-26 00:00:00

abstract：:Sensitisation of the capsaicin receptor, transient receptor potential vanilloid type 1 (TRPV1) ion channel in nociceptive primary sensory neurons (PSN) underlies the development of inflammatory heat hyperalgesia. Removal of the negative-dominant splice variant of the TRPV1 molecule, TRPV1b from TRPV1/TRPV1b heterotetr...

journal_title：Neuroscience letters

authors： Mistry S,Paule CC,Varga A,Photiou A,Jenes A,Avelino A,Buluwela L,Nagy I

更新日期：2014-04-03 00:00:00

abstract：:Quantitative neurophysiological studies have identified the presence of at least two spinal neuron populations (ABRUPT and SUSTAINED) which are excited by the noxious visceral stimulus colorectal distension (CRD). The present study examined the effects of acute colorectal inflammation on the activity of dorsal horn ne...

journal_title：Neuroscience letters

authors： Ness TJ,Gebhart GF

更新日期：2000-03-10 00:00:00

abstract：:Noradrenaline enhanced in a concentration-dependent way the basal release of endogenous GABA from superfused rat hippocampus synaptosomes. The alpha 2-adrenoceptor antagonist yohimbine prevented the releasing effect of noradrenaline while the alpha 1-adrenoceptor antagonist prazosin was ineffective. It is concluded th...

journal_title：Neuroscience letters

authors： Pittaluga A,Raiteri M

更新日期：1987-05-19 00:00:00

abstract：:The effects of gonadal steroids on serotonin (5-HT) synthesis and metabolism in the early developing brain were investigated. Seven-day-old (7 days post-hatch) tilapia, Oreochromis mossambicus were continuously treated with 17beta-estradiol (E2), methyltestosterone (MT) and para-chlorophenylalanine (p-PCA) up to the a...

journal_title：Neuroscience letters

authors： Tsai CL,Wang LH

更新日期：1999-04-02 00:00:00