Abstract:
:Day-old chickens trained in pairs on an aversive discrimination task yielded a retention function with two points of reduced retention, at 15 and 55 min after learning. These points of temporary reduction in retention were interpreted as reflecting change-over of recall from three successive phases in memory formation. Chicks trained in isolation showed the same retention function as paired chicks except that the second point of reduced retention occurred at 70 min after learning. It was suggested that isolation prolonged the availability for recall of the second phase of memory formation. The findings are consistent with and support a three phase, behaviourally sequentially dependent, model of memory formation previously postulated on the basis of pharmacological studies.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Gibbs ME,Ng KTdoi
10.1016/0304-3940(79)91507-6subject
Has Abstractpub_date
1979-08-01 00:00:00pages
279-83issue
3eissn
0304-3940issn
1872-7972pii
0304-3940(79)91507-6journal_volume
13pub_type
杂志文章abstract::The horizontal vestibulo-ocular reflex (VOR) of two groups of rats was measured. One group was bred and kept under hypergravity (HG; 2.5 g) conditions, the other group lived under normal gravity (NG; 1 g). Eye position was recorded in response to horizontal rotatory stimuli. Measurements were made under NG (1 g), and ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(01)01691-3
更新日期:2001-04-27 00:00:00
abstract::Mechanisms of neuropathic pain are not clear. Recently we showed long-term potentiation (LTP) of wide dynamic range (WDR) neurones after electrical conditioning stimulation of the sciatic nerve in normal rats. In this study we investigated the effects of the same conditioning on both the evoked responses of WDR cells ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(00)01201-5
更新日期:2000-07-14 00:00:00
abstract::The bindings of [3H](R) alpha-methylhistamine to histamine H3 receptors were investigated in rat brain following intranigral treatment with 6-hydroxydopamine (6-OHDA) by quantitative receptor autoradiography. The levels of [3H](R) alpha-methylhistamine binding sites in the denervated striatum (dorsomedial and dorsolat...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(94)90279-8
更新日期:1994-08-29 00:00:00
abstract::The latency, duration of feeding and number of feeding periods recorded from rats after noradrenaline injection to the hippocampus show little change after unilateral 6-hydroxydopamine injections to the substantia nigra. It is suggested that 6-hydroxydopamine-induced weight losses result from non-specific effects of i...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(77)90194-x
更新日期:1977-04-01 00:00:00
abstract::Functioning of the hypothalamo-pituitary-adrenocortical axis was assessed in rats treated with DSP-4 (N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine), a selective noradrenergic neurotoxin. Although adrenal weights were slightly increased 10 days after DSP-4 injection, basal plasma corticosterone levels were unaltered co...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(84)90111-3
更新日期:1984-05-18 00:00:00
abstract::The standard pseudohomophone effect in the lexical decision task, i.e. longer response times and higher error rates for pseudohomophones compared with spelling controls, is commonly explained by an orthography-phonology-conflict. This study tested this conflict account, using a multi-method approach including particip...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2009.03.010
更新日期:2009-05-15 00:00:00
abstract::Genetic factors have been reported to contribute to the liability of suicide. We aimed to investigate functional polymorphisms in eight genes (serotonin transporter, SLC6A4; receptors, 5HTR1A, 1B, 5HTR2A; Tryptophan Hydroxylase, TPH1, TPH2; Monoamine Oxidase, MAOA and G Protein Subunit Beta 3, GNB3) to investigate the...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2017.07.020
更新日期:2017-08-24 00:00:00
abstract::Administration of the cannabinoid CB1 receptor antagonist SR141716 (3-10 mg/kg i.p.) abolished neuropeptide Y-induced overeating and significantly reduced ethanol and sucrose intake in CB1 wild-type (+/+) mice. In CB1 receptor knockout (-/-) mice, neuropeptide Y totally lost its capacity to increase food consumption. ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(03)00397-5
更新日期:2003-06-12 00:00:00
abstract::Neural stem cells (NSCs) have been the focus of an intensive effort to direct their differentiation in vitro towards desired neuronal phenotypes for cell replacement therapies. It is thought that NSCs derived from older embryos have limited neurogenic capacity and are restricted towards an astroglial fate. This idea i...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2013.12.009
更新日期:2014-01-24 00:00:00
abstract::The gamma aminobutyric acid (GABA) system has been implicated in the susceptibility to develop alcohol dependence and in determining electroencephalogram (EEG) beta activity. The role of the GABA receptor alpha-2 gene (GABRA2) in human alcohol dependence was determined in a genetic and electrophysiological study. The ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2011.05.240
更新日期:2011-08-18 00:00:00
abstract::Novel paired ependymal ridges (EPRS) have been identified in the ventrolateral wall of the cerebral aqueduct of the rat. Scanning electron microscopic techniques revealed that the dorsolateral and ventromedial ridges differ from each other in surface morphology. Using the PAP immunohistochemical technique, the EPRS de...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(81)90196-8
更新日期:1981-11-18 00:00:00
abstract::The aim of the present study was to assess reorganization in the motor cortex of patients with lower limb amputation. We studied seven patients with traumatic lower limb amputation, and six healthy controls, using transcranial magnetic stimulation mapping, with recordings from the quadriceps femoris muscle on both sid...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(03)00838-3
更新日期:2003-10-09 00:00:00
abstract::Neurons simultaneously immunoreactive with anti-beta-endorphin and anti-(17-39) corticotropin (anti(17-39) ACTH) have been detected in the arcuate and ventromedial nuclei of the hypothalamus of colchicine-treated rats. These neurons are different from those fluorescent with the Falck and Hillarp technique. These resul...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(79)95341-2
更新日期:1979-09-01 00:00:00
abstract::Cat odor elicits defensive responses in rats that are modified by repeated exposure to the odor. We explored the neural correlates of this adaptation using FosB/DeltaFosB immunohistochemistry. Rats were given 3 x60 min exposures to either a worn cat collar (repeated cat odor group) or unworn cat collar (control group)...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2009.06.069
更新日期:2009-09-22 00:00:00
abstract::The opioid peptide dynorphin decreased somatic calcium-dependent action potential duration in a portion of mouse dorsal root ganglion (DRG) neurons without altering resting membrane potential or conductance. Dynorphin action was antagonized by naloxone. Responses of DRG neurons to dynorphin differed from responses to ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(84)90439-7
更新日期:1984-05-04 00:00:00
abstract::Recombinant gamma-aminobutyric acid (GABA(A)) receptor channels containing alpha1beta2gamma2-subunits were transiently expressed in HEK293 cells. Modulation by diazepam (DZ) was investigated using the patch-clamp technique with a device for ultra-fast solution exchange. GABA activated Cl(-)-currents were potentiated w...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(98)00767-8
更新日期:1998-11-13 00:00:00
abstract::It has been proposed that the perception of a coherent image necessitates two processes, that is, an ensemble of neurons which synchronizes discharges of individual cells and stimulus-specific gamma-band (gamma) neuronal oscillations which may serve as carrier signals for a temporal code. We tested the hypothesis that...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(99)00497-8
更新日期:1999-09-10 00:00:00
abstract::The availability of choline during the prenatal period influences neural and cognitive development. Here we report that choline supplementation during a six-day gestational period protects against neurodegeneration in the posterior cingulate and retrosplenial cortices of adult female rats produced by systemic administ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(03)00119-8
更新日期:2003-05-01 00:00:00
abstract::Nerve growth factor (NGF) initially interested neurobiologists because of its effects in the developing nervous system. It is now clear that NGF functions throughout the life of the animal with a wide repertoire of actions. In the sensory nervous system it primarily influences the structure and function of nociceptors...
journal_title:Neuroscience letters
pub_type: 杂志文章,评审
doi:10.1016/j.neulet.2003.12.012
更新日期:2004-05-06 00:00:00
abstract::A characteristic of Parkinson's disease (PD) is the development of tremor within the 4-6Hz range. One method used to better understand pathological tremor is to compare the responses to tremor-type actions generated intentionally in healthy adults. This study was designed to investigate the similarities and difference...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2012.11.040
更新日期:2013-02-08 00:00:00
abstract::Mere observation of objects in our surroundings can potentiate movement, a fact reflected by visually-primed activation of motor cortical networks. This mechanism holds potential value for reactive balance control where recovery actions of the arms or legs must be targeted to a new support base to avoid a fall. The pr...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2018.05.040
更新日期:2018-09-14 00:00:00
abstract::Genome-wide analysis of miRNA expression has revealed increased levels of miR-144 in the brains of Alzheimer's disease (AD) patients. Nuclear factor erythroid 2-related factor 2 (NRF2), a potential target of miR-144, is a central regulator of antioxidant response, and plays an important role in glutathione (GSH) biosy...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2017.06.045
更新日期:2017-08-10 00:00:00
abstract::The effect of 4-aminopyridine (4-AP) on long-term potentiation (LTP) was studied in the hippocampal slice preparation of the rat. Field excitatory postsynaptic potentials (EPSPs) were recorded and evoked in the stratum radiatum of the CA1. Both the low frequency EPSP and LTP of the EPSP were significantly increased by...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(86)90446-5
更新日期:1986-09-25 00:00:00
abstract::The spontaneous electrical activity of single neurons of the midbrain dorsal raphe nucleus in the rat was recorded in vitro in 400 mum thick slices. The majority of raphe neurons exhibited the slow and regular discharge pattern that characterizes the activity of raphe neurons when recorded in vivo. The viability of th...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(76)90014-8
更新日期:1976-06-01 00:00:00
abstract::Intolerance of uncertainty (IU), or the increased affective response to situations with uncertain outcomes, is an important component process of anxiety disorders. Increased IU is observed in panic disorder (PD), obsessive compulsive disorder (OCD) and generalized anxiety disorder (GAD), and is thought to relate to dy...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.10.030
更新日期:2008-01-10 00:00:00
abstract::Tris-HCl is the most commonly used buffer in studies of radioligand binding to sigma receptors, with concentrations as high as 50 or 100 mM often used. We report here that these concentrations of Tris substantially inhibit (+)-[3H]SKF-10,047 binding to sigma receptors. The well-established inhibitory effect of Tris-HC...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(92)90903-k
更新日期:1992-07-20 00:00:00
abstract::Somatosensory evoked potentials to median nerve (MN) stimulation were recorded by stereotactically implanted electrodes in the frontal lobe of two epileptic patients in order to evaluate whether short-latency cortical responses could be generated in the supplementary motor area (SMA)-proper. In both patients two poten...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(03)00378-1
更新日期:2003-07-03 00:00:00
abstract::The present study was designed to determine potential associations between the brain damage induced by hypoxic-ischemic (HI) insult and spatial learning impairment in an eight-arm radial maze task. We first determined the pathological outcomes after 2, 5, 9, and 17 weeks of recovery following the HI insult. The result...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2004.11.055
更新日期:2005-03-16 00:00:00
abstract::The intracellular stress-induced proteins provide protection against toxic insults. Here, a 60,000-Da heat shock 60 (hsp60)-like protein was detected, with five different antibodies, in conditioned media derived from rat cortical astrocytes and a human neuroblastoma cell line. Extracellular neuroblastoma hsp60-like im...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(98)00428-5
更新日期:1998-06-26 00:00:00
abstract::Injection of the triceps brachii muscle of the rat with horseradish peroxidase (HRP) led to labeling of motoneurons in the dorsolateral and ventral aspects of the ventral grey horn of the brachial spinal cord. Ventral, labeled neurons were absent, however, in rats in which the motor branches of the radial nerve to tri...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(85)90596-8
更新日期:1985-10-10 00:00:00