Abstract:
:The standard pseudohomophone effect in the lexical decision task, i.e. longer response times and higher error rates for pseudohomophones compared with spelling controls, is commonly explained by an orthography-phonology-conflict. This study tested this conflict account, using a multi-method approach including participant's behavioral responses, confidence ratings, pupillary responses and event-related potentials (ERPs). The classic pseudohomophone effect was replicated using relatively long, multi-syllabic stimuli. Pseudohomophones were rated less confidently as being nonwords than spelling controls, and they affected the pupillary response by increasing the peak pupil diameter. Both findings are interpreted in terms of increased conflict and higher cognitive demands leading to uncertainty while solving the task. The ERP revealed an N400 component for spelling controls, showing a graded effect: word journal_name journal_title authors doi subject pub_date pages issue eissn issn pii journal_volume pub_type
abstract::Little is known about the effect of wnt-3a on motor nerve function and its specific molecular mechanisms after spinal cord injury (SCI). This study demonstrates that the downregulated expression levels of caspases-3, caspases-9 and chondroitin sulfate proteoglycan (CSPG) proteins and number of proportion of transferas...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2020.135305
更新日期:2020-10-15 00:00:00
abstract::We evaluated long-term dynorphin A-immunoreactivity in the rat area postrema (AP) after the administration of cisplatin. First, rats were given 1, 5 and 10mg/kg body weight cisplatin (i.p.) and their behavior was monitored for 72h. We observed a delayed increase in pica 24-72h after injection, compared to the 24h befo...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.07.044
更新日期:2007-09-07 00:00:00
abstract::The present study was designed to determine whether the p53 tumor-suppressor protein is involved in the development of antinociceptive tolerance to morphine. When the doses of morphine (mg/kg per injection) were subcutaneously given into mice as pretreatment twice daily for 2 days (first day (30) and second day (60)),...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2008.11.061
更新日期:2009-02-06 00:00:00
abstract::A new non-N-methyl-D-aspartate (non-NMDA) glutamate receptor antagonist, GYKI 52466, was tested on L-glutamate (Glu)-, kainate (KAI)- and NMDA-induced responses in vivo, using both extracellular recording of antidromic field potentials and intracellular recording from rat abducens motoneurones. Intravenous (5-10 mg/kg...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(91)90115-a
更新日期:1991-04-15 00:00:00
abstract::The antinociceptive action of cannabinoids in acute and inflammatory pain states have been well-documented. There is also accumulating evidence suggesting that cannabinoids are effective analgesics in chronic pain conditions. WIN 55,212-2, a mixed CB1 and CB2 cannabinoid receptor agonist, has been shown to be effectiv...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2004.08.061
更新日期:2004-11-23 00:00:00
abstract::Ketogenic diets (KD) have shown beneficial effects in terms of anticonvulsant and anti-epileptogenic properties in several experimental models. However, few studies have investigated the consequences of KD with regards to the anti-epileptogenic and neuroprotective effects in kindling-induced seizures. Here, postnatal ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2011.12.002
更新日期:2012-02-02 00:00:00
abstract::It is known that 5HTR2A (rs6311) receptors have high concentration in the cortical layer-5 pyramidal neurons and that these receptors play an important role in the modulation of neurocognitive functions. For example, layer-5 pyramidal neurons mediate cellular level integrative interaction of primary sensory afferent s...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2014.10.015
更新日期:2015-01-01 00:00:00
abstract::Alterations in the structure and physiology of the prefrontal cortex (PFC) have been found in different psychiatric disorders and some of them involve inhibitory networks, especially in schizophrenia and major depression. Changes in the structure of these networks may be mediated by the polysialylated neural cell adhe...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2012.09.032
更新日期:2012-11-14 00:00:00
abstract::Febrile seizures (FS) are generally defined as seizures taking place during fever. Long-term prognosis, including development of epilepsy and malformation of cognitive function, has been demonstrated after infantile FS. However, the mechanism that triggers seizures in hyperthermic environment is still unclear. We here...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2014.08.037
更新日期:2014-10-03 00:00:00
abstract::Motoneuron death induced by sciatic nerve transection in neonatal rats has been related to induction of the neuronal isoform of nitric oxide synthase (nNOS), a diaphorase of which one of the cofactors is nicotinamide adenine dinucleotide phosphate (NADPH). We transected the sciatic nerve of neonatal rats (P2) and exam...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(01)01931-0
更新日期:2001-07-13 00:00:00
abstract::Glucose is an important metabolic factor controlling feeding behavior. There is evidence that physiologically relevant glucose sensors reside in the caudal hindbrain. The area postrema (AP) in particular, which has been characterized as a receptive site for the anorectic hormone amylin, may monitor blood glucose level...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(02)00482-2
更新日期:2002-08-09 00:00:00
abstract::A characteristic of Parkinson's disease (PD) is the development of tremor within the 4-6Hz range. One method used to better understand pathological tremor is to compare the responses to tremor-type actions generated intentionally in healthy adults. This study was designed to investigate the similarities and difference...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2012.11.040
更新日期:2013-02-08 00:00:00
abstract::Recent findings document numerous interactions between neuronal and glial systems that likely play a role in the pathophysiology of depression. These findings suggest that glia-derived neurotrophic protein S100B may play a significant role in developing depression. To test the relationship between S100B and depressive...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2012.09.003
更新日期:2012-11-07 00:00:00
abstract::Bilateral, radiofrequency destruction of the hypothalamic paraventricular nucleus resulted in a pronounced depression in levels of immunoreactive (ir-) vasopressin (VP) in the medulla-pons of rats. The contents of ir-dynorphin1-17 (DYN), ir-DYN1-8 and ir-alpha-neo-endorphin (alpha-NE) therein were not, in contrast, af...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(82)90170-7
更新日期:1982-12-30 00:00:00
abstract::Recent studies have demonstrated that genetic factors modify susceptibility to sporadic Parkinson's disease (PD). So far the results of candidate gene studies have been conflicting. It has been suggested that polymorphisms in apolipoprotein E (APOE), PARKIN and catechol-O-methyltransferase (COMT) genes might increase ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(02)00819-4
更新日期:2002-09-27 00:00:00
abstract::Mental simulation of movements has been widely used to infer about representational aspects of action. On a daily basis, motor planning and execution depends crucially both upon vision and kinesthesia. What if the former is lost? In this study we investigate the physiological changes induced during a mental simulation...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2006.02.042
更新日期:2006-05-29 00:00:00
abstract::The factors determining the large variation seen in human corpus callosum (CC) morphology are as yet unknown. In this study heritability of CC size was assessed by comparing the concordance of CC midsagittal area in 14 monozygotic and 12 dizygotic twin pairs with a mean age of 27 years, using magnetic resonance imagin...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(02)01333-2
更新日期:2003-02-27 00:00:00
abstract::By means of a new photographic method to quantitate catecholamine fluorescence in tissue sections it has been possible to demonstrate a high dopamine (DA) turnover within the DA cell bodies of the midbrain. The medially located small-sized DA cell bodies of the A10 DA cell group has a very high DA turnover which was s...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(80)90211-6
更新日期:1980-05-15 00:00:00
abstract::Tripeptidyl peptidase-I (TPP-I) is a lysosomal exopeptidase which removes tripeptides from the N-terminus of small proteins. Mutations in the TPP-I gene result in a lethal neurodegenerative disease, late infantile neuronal ceroid lipofuscinosis. The pathological consequences of loss of activity are only manifested in ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(02)00841-8
更新日期:2002-10-11 00:00:00
abstract::In urethane-anesthetized rats single neuronal activity was recorded in the laterodorsal tegmental nucleus (LDT), which has a dense complement of cholinergic neurons, and in the dorsal raphe and locus coeruleus for comparison. Most LDT neurons responded antidromically to stimulation of either one or more of several ros...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(87)90512-x
更新日期:1987-06-26 00:00:00
abstract::In newborns, hypoxia elicits defensive behaviors including awakening from sleep, body movements and crying. An inability to produce this defense response is a risk factor for sudden infant death syndrome and other respiratory control disorders. In this study, we examined the possibility that the defense response to hy...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.05.012
更新日期:2007-06-15 00:00:00
abstract::Stress increases associative learning and the density of dendritic spines in the hippocampus of male rats. In contrast, exposure to the same stressor impairs associative learning and reduces spine density in females. These effects in females are most evident when they are in the proestrus phase of the estrous cycle. A...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2008.10.051
更新日期:2009-01-02 00:00:00
abstract::Mutations in the glucocerebrosidase gene (GBA) have recently been associated with an increased risk of Parkinson disease (PD). GBA mutations have been observed to be particularly prevalent in the Ashkenazi Jewish population. Interestingly, this population also has a high incidence of the Lrrk2 p.G2019S mutation which ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2009.11.066
更新日期:2010-06-21 00:00:00
abstract::We tested the hypothesis that intracerebroventricular (i.c.v.) administration of leptin would increase mean arterial pressure (MAP) in ad libitum (AL) fed and food deprived (FD) normotensive rats. Male Sprague-Dawley rats were chronically instrumented with a guide cannula directed at the lateral ventricle and a caroti...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(98)00223-7
更新日期:1998-04-17 00:00:00
abstract::Neuronal cell death induced by ischemic injury has been attributed to glutamate receptor-mediated excitotoxicity, which is known to be accompanied by Ca2+ overload in the cytoplasm with concomitant activation of calcium-dependent mechanisms. More specifically, the overactivation of calpains, calcium-dependent cysteine...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2020.135265
更新日期:2020-09-25 00:00:00
abstract::We measured levels of basal and norepinephrine (NE) -induced melatonin release in cultured pineal bodies of rats just after and 2 days after irradiation (20 or 200 Gy) or sham-irradiation. On the day of irradiation, basal and NE-induced melatonin release were not affected by irradiation. Two days after irradiation, ba...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(00)00984-8
更新日期:2000-04-21 00:00:00
abstract::This study reports the solubilization of the rat synaptic vesicle protein SV2A, the brain binding site for the antiepileptic drug levetiracetam (LEV), and its characterization. N-dodecyl-beta-D-maltoside (DDM) was the best detergent at achieving a high percentage of SV2A solubilization and at maintaining the binding c...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2005.12.059
更新日期:2006-05-01 00:00:00
abstract::The neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal total biopterin were examined both in rats and mice at different time courses. Results indicate that MPTP caused a significant decrease of total biopterin content in the striatum of mice. This effect occurred as soon as 6 h after...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90227-3
更新日期:1988-06-07 00:00:00
abstract::The somatosensory homunculus has been identified during stimulation of median (at wrist and elbow), femoral, tibial and pudendal nerves of the left hemibody via the neuromagnetic imaging technique. The somatic representations of different body districts have been localized in the somatosensory cortex, by means of an e...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(91)90647-c
更新日期:1991-01-02 00:00:00
abstract::Paramethoxyphenylethylamine (PMPEA) is a sympathomimetic amine, like its parent compound, phenylethylamine. The intraperitoneal administration of PMPEA to mice produces a dose-dependent depletion of brain and heart norepinephrine, with significant reduction being observed one hour postinjection. At lower dosages, PMPE...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(75)90033-6
更新日期:1975-09-01 00:00:00