Tris inhibits (+)-[3H]SKF-10,047 binding to sigma receptors.

abstract：:Freshly dissected chick neural retina and pigmented epithelium do not apparently contain asymmetric molecular forms (A-forms) of acetylcholinesterase (AChE). The neighboring choroid, and the ciliary muscles and iris, are however rich in type II A-forms (high salt/EDTA-extractable). Most if not all the asymmetric AChE ...

journal_title：Neuroscience letters

authors： Barat A,Ramos M,Prada C,Ramírez G

更新日期：1990-05-04 00:00:00

abstract：:Prior work demonstrated that immune surveillance of the brain occurs primarily through the blood-cerebrospinal (CSF) fluid barrier rather than the blood-brain barrier endothelium. Recently, we identified epithelial V-like antigen (EVA), an immunoglobulin-like adhesion molecule, as a regulator of blood-CSF barrier inte...

journal_title：Neuroscience letters

authors： Wojcik E,Carrithers LM,Carrithers MD

更新日期：2011-05-16 00:00:00

abstract：:During hibernation the body temperature of the golden-mantled ground squirrel, Spermophilus lateralis, may drop below 5 degrees C for a few hours to a week or more. Animals cycle between euthermia and deep hibernation many times over the course of the hibernation season. Expression of the transcription factor c-fos in...

journal_title：Neuroscience letters

authors： Bitting L,Sutin EL,Watson FL,Leard LE,O'Hara BF,Heller HC,Kilduff TS

更新日期：1994-01-03 00:00:00

abstract：:This study analysed the equilibrium strategies and EMG activity during postural equilibrium in four different unstable surfaces. Thirteen team sport males were tested on a FLAT surface and on three different wobble boards (JAKOBS(®) with easy multidirectional displacements, FREEMAN with strong multidirectional displac...

journal_title：Neuroscience letters

authors： Cimadoro G,Paizis C,Alberti G,Babault N

更新日期：2013-08-26 00:00:00

abstract：:The distribution of substance P (SP)-like immunoreactivity in the rat retina was investigated by immunohistochemistry. SP-positive cells were found throughout the retina. The majority of them were located in the proximal portion of the inner nuclear layer and the processes from these cells directed to the inner plexif...

journal_title：Neuroscience letters

authors： Fukuda M,Kuwayama Y,Shiosaka S,Ishimoto I,Shimizu Y,Takagi H,Inagaki S,Sakanaka M,Semba E,Takatsuki K,Tohyama M

更新日期：1981-05-29 00:00:00

abstract：:Hyperglycemia is common and associated with poor outcome in acute ischemic stroke patients. Neutrophil extracellular traps (NETs) are increased either in diabetes or ischemic stroke. We aimed to determine the role of NETs in acute ischemic stroke with hyperglycemia as it has not been clarified. NETs were observed in t...

journal_title：Neuroscience letters

authors： Deng J,Zhao F,Zhang Y,Zhou Y,Xu X,Zhang X,Zhao Y

更新日期：2020-11-01 00:00:00

abstract：:Statins were recently shown to possess anti-inflammatory activities, which might be responsible for their favourable effects in cardiovascular or CNS disorders independently from the inhibition of hydroxy-methyl-glutaryl CoA reductase. Here we investigated the effects of the statins lovastatin and mevastatin on prosta...

journal_title：Neuroscience letters

authors： Tringali G,Vairano M,Dello Russo C,Preziosi P,Navarra P

更新日期：2004-01-09 00:00:00

abstract：:Stereotaxic microinjection of herpes simplex virus (HSV) into the mouse olfactory bulb resulted in infection of neurons of the piriform cortex. Neurons infected with the wildtype HSV showed no evident phosphorylation of c-Jun N-terminal protein kinase (JNK)/c-Jun. In contrast, neurons infected with a US3 gene-disrupte...

journal_title：Neuroscience letters

authors： Mori I,Goshima F,Koshizuka T,Koide N,Sugiyama T,Yoshida T,Yokochi T,Kimura Y,Nishiyama Y

更新日期：2003-11-20 00:00:00

abstract：:Rat myotubes were cultured with embryonic mouse spinal cord explants. After 4 days of co-culture, (miniature) endplate potentials, (M)EPPs, could be detected in 20-40% of the nerve-contacted myotubes. Polyclonal antibodies against the neural cell adhesion molecule N-CAM and monoclonal antibodies to its L2/HNK-1 carboh...

journal_title：Neuroscience letters

authors： Mehrke G,Jockusch H,Schachner M

更新日期：1987-08-05 00:00:00

abstract：:A right-brain damaged patient with pure tactile extinction was asked to report series of single or double light, brief touches delivered to both hands, the thumb or the pinkie of a single hand, the sides of a single index. The stimulated hand was positioned palm up or palm down, in front of or behind the patient, in a...

journal_title：Neuroscience letters

authors： Tinazzi M,Ferrari G,Zampini M,Aglioti SM

更新日期：2000-06-23 00:00:00

abstract：:Freshly isolated or culture-expanded human umbilical cord blood mononuclear cells (CBMNCs) have been known to express neural phenotypes in vitro and to differentiate into neural cells and improve neurological function recovery after being administrated into rodent models of neurological diseases. However, the mechanis...

journal_title：Neuroscience letters

authors： Fan CG,Zhang QJ,Tang FW,Han ZB,Wang GS,Han ZC

更新日期：2005-06-03 00:00:00

abstract：:The neurotoxin 6-hydroxydopamine (6-OHDA) is used to induce dopaminergic cell death, resulting in insufficient striatal dopamine content in the basal ganglia and motor dysfunction typical of Parkinson's disease. Dopamine induces release of the neuropeptide substance P (SP) within the substantia nigra, whereas SP is ab...

journal_title：Neuroscience letters

authors： Thornton E,Tran TT,Vink R

更新日期：2010-08-30 00:00:00

abstract：:The activation of immature rat S1 neocortex by electrical stimulation of peripheral nerves and of the thalamus is described. The existence of a surface-positive potential of intracortical origin at an early stage of development is confirmed. It is also shown that both the augmenting and the recruiting phenomena can be...

journal_title：Neuroscience letters

authors： Verley R,Axelrad H

更新日期：1975-08-01 00:00:00

abstract：:The effect of bifemelane hydrochloride (BFH) on the induction of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient global ischemia in gerbil brain was investigated by in situ hybridization using cloned cDNA probes selective for each mRNA species. Following 3.5 min of ischemia, H...

journal_title：Neuroscience letters

authors： Aoki M,Abe K,Liu XH,Lee TH,Kato H,Kogure K

更新日期：1993-05-14 00:00:00

abstract：:Functional MRI studies have revealed that the brain activity in the anterior temporal cortex during memory retrieval increases over months after memory encoding. Behavioral evidence has demonstrated that long-term memory can sometimes be consolidated more rapidly in one or two days. In the present functional MRI study...

journal_title：Neuroscience letters

authors： Jimura K,Hirose S,Wada H,Yoshizawa Y,Imai Y,Akahane M,Machida T,Shirouzu I,Koike Y,Konishi S

更新日期：2016-08-03 00:00:00

abstract：:The purpose of the study was to assess corticospinal excitability of the biceps brachii in the non-dominant arm of chronic resistance-trained (RT) and non-RT individuals. Seven chronic-RT and six non-RT male participants performed 4 sets of 5s pseudo-randomized contractions of the non-dominant elbow flexors at 25, 50,...

journal_title：Neuroscience letters

authors： Philpott DT,Pearcey GE,Forman D,Power KE,Button DC

更新日期：2015-01-12 00:00:00

abstract：:The effects of Sr2+ on the transmitter release at the frog neuromuscular junction were examined electrophysiologically. The nerve trunk was stimulated by paired pulses at various time intervals after replacing extracellular Ca2+ by Sr2+, the paired-pulse facilitation at the 10 ms interval was smaller than that at 20-3...

journal_title：Neuroscience letters

authors： Tanabe N,Morota A

更新日期：1999-11-19 00:00:00

abstract：:[3H] Overflow evoked by 5 min supramaximal preganglionic stimulation at 1 pps has been studied in isolated guinea pig superior cervical ganglion preparations preincubated with [3H]choline. At 15 microM norepinephrine (NE) reduced both the [3H]choline overflow and endogenous acetylcholine release by 59.4 and 54.1% resp...

journal_title：Neuroscience letters

authors： Belluzzi O,Travagli RA,Bonifazzi C,Perri V

更新日期：1987-01-02 00:00:00

abstract：:Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are chemogenetic tools commonly-used to manipulate brain activity. The most widely-used synthetic DREADD ligand, clozapine-N-oxide (CNO), is back-metabolized to clozapine which can itself activate endogenous receptors. Studies in non-DREADD-expressin...

journal_title：Neuroscience letters

authors： Tran FH,Spears SL,Ahn KJ,Eisch AJ,Yun S

更新日期：2020-11-20 00:00:00

abstract：:The effect of the neuropeptide, substance P, on the transport of D-[(3)H]aspartate into rat striatal synaptosomes was studied. Almost 90% of the total transport of D-[(3)H]aspartate was sodium-dependent and the maximum rate (V(max)) of this transport was increased by 34% of control by 2.5 nM substance P (EC(50)=0.52 n...

journal_title：Neuroscience letters

authors： Healy J,Downes A,McBean GJ

更新日期：2000-08-25 00:00:00

abstract：:Brachial plexus avulsion (BPA) is one of the major injuries in motor vehicle accidents and may result in neuropathic pain. Accumulating evidence suggests that 30-80% of BPA developed neuropathic pain in human. In our study, complete brachial plexus avulsion (C5-T1) rats model leads to the results that 37.5% of rats ha...

journal_title：Neuroscience letters

authors： Wang L,Yuzhou L,Yingjie Z,Jie L,Xin Z

更新日期：2015-03-04 00:00:00

abstract：:Results from various genetic association studies of the lipoprotein lipase (LPL) S447X polymorphism and Alzheimer's disease (AD), range from a statistically significant negative association of clinically examined patients to a non-significant but consistent trend for under-representation of the X447 allele in neuropat...

journal_title：Neuroscience letters

authors： Fidani L,Compton D,Hardy J,Petersen RC,Tangalos E,Mirtsou V,Goulas A,De Vrieze FW

更新日期：2002-04-12 00:00:00

abstract：:Intrinsically bursting (IB) neurons, responding with a burst of action potentials to just threshold intracellular depolarizing current pulses, are encountered in layer V of mature rodent sensorimotor cortex. We report the results of intracellular recordings performed on neocortical slices obtained from immature rats b...

journal_title：Neuroscience letters

authors： Franceschetti S,Buzio S,Sancini G,Panzica F,Avanzini G

更新日期：1993-11-12 00:00:00

abstract：:Kynurenic acid (KYNA), a neuroactive metabolite of tryptophan that acts on different receptors (e.g. those of N-methyl-D-aspartate (NMDA) and presynaptic α7 nicotinic acetylcholine (nACh)), exerts fundamentally antiglutamatergic effects. In view of its antiglutamatergic properties, an elevation of the KYNA level withi...

journal_title：Neuroscience letters

authors： Demeter I,Nagy K,Farkas T,Kis Z,Kocsis K,Knapp L,Gellert L,Fülöp F,Vecsei L,Toldi J

更新日期：2013-10-11 00:00:00

abstract：:Ferumoxytol is an ultrasmall superparamagnetic iron oxide (USPIO) nanoparticle that is FDA-approved as an intravenous iron replacement therapy for the treatment of iron deficiency anemia in patients with chronic kidney disease. Ferumoxytol has also been used as a contrast agent for cerebral blood volume mapping by mag...

journal_title：Neuroscience letters

authors： Doyle KP,Quach LN,Arceuil HE,Buckwalter MS

更新日期：2015-01-01 00:00:00

abstract：:In the brains of male zebra finches (Taeniopygia guttata), the nuclei that direct song learning and production are larger than the corresponding regions in females, who do not sing. The dimorphism in Area X of the medial striatum (MSt), an area important for song learning, is even more dramatic in that it is identifia...

journal_title：Neuroscience letters

authors： Bailey DJ,Wade J

更新日期：2006-06-19 00:00:00

abstract：:Sertindole has been marketed and offered daily clinical practice only for 9 months in our country, so no data has been its QTc prolongation potential. In the present study, we performed a clinical trial to investigate the effects of sertindole on QTc in patients with schizophrenia. The study comprised 21 patients with...

journal_title：Neuroscience letters

authors： Atmaca M,Yavuzkir M,Mermi O,Topuz M,Kanmaz E,Tezcan E

更新日期：2008-09-05 00:00:00

abstract：:Acrolein-induced oxidative stress is hypothesized to involve in the etiology of Alzheimer's disease (AD). Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) have antioxidative and neuroprotective properties. The present study investigated the protective effects of CA/CAPE on acrolein-induced oxidative neuronal ...

journal_title：Neuroscience letters

authors： Huang Y,Jin M,Pi R,Zhang J,Chen M,Ouyang Y,Liu A,Chao X,Liu P,Liu J,Ramassamy C,Qin J

更新日期：2013-02-22 00:00:00

abstract：:Rats with suprachiasmatic nuclei (SCN) lesions did not show increased sleep after triazolam (TRZ) injections at any dose from 0.2 to 1.6 mg/kg, whereas 0.4 mg/kg TRZ given intact rats in the middle of their activity phase significantly increased sleep. Across SCN-lesioned and intact rats, the amount of sleep before an...

journal_title：Neuroscience letters

authors： Edgar DM,Seidel WF,Martin CE,Sayeski PP,Dement WC

更新日期：1991-04-29 00:00:00

abstract：:To determine whether a trans-synaptic mechanism triggered the effects of reserpine on adrenomedullary mRNAs encoding the norepinephrine transporter and tyrosine hydroxylase, we administered 10 mg/kg reserpine to rats after unilateral splanchnicotomy, and examined their adrenal medullas using quantitative in situ hybri...

journal_title：Neuroscience letters

authors： Cubells JF,Baker H,Volpe BT,Smith GP,Das SS,Joh TH

更新日期：1995-07-07 00:00:00