Neutrophil extracellular traps increased by hyperglycemia exacerbate ischemic brain damage.

abstract：:Very recent studies in adult gerbils and rats have shown that exposure to sublethal ischemia can confer neuroprotection from subsequent lethal ischemic episodes. To determine if a similar phenomenon can be elicited during the perinatal period, we have developed a preconditioning regimen that involves exposure to normo...

journal_title：Neuroscience letters

authors： Gidday JM,Fitzgibbons JC,Shah AR,Park TS

更新日期：1994-02-28 00:00:00

abstract：:The in vivo effects of the alpha 2-adrenoceptor idazoxan, rauwolscine and phentolamine on alpha 2-auto/heteroreceptors and 5-HT1A autoreceptors modulating the synthesis of dopa/noradrenaline and 5-HTP/serotonin were assessed in rats, using the accumulation of dopa and 5-HTP after decarboxylase inhibition as a measure ...

journal_title：Neuroscience letters

authors： Lladó J,Esteban S,García-Sevilla JA

更新日期：1996-11-01 00:00:00

abstract：:The inferior alveolar nerves (IAN) of young male Wistar rats (b.wt. greater than or equal to 200 g) were transected unilaterally, slightly proximal to the mandibular foramen under anesthesia with chloral hydrate (0.4 g/kg, i.p.). After various postoperative periods of time, the animals received horseradish peroxidase ...

journal_title：Neuroscience letters

authors： Takemura M,Sugimoto T,Wakisaka S,Akai M

更新日期：1990-01-01 00:00:00

abstract：:The area surrounding the injured spinal cord is a non-permissive milieu for axonal growth due to the inhibitory factors, especially chondroitin sulfate proteoglycan (CSPG) and Nogo. Recent studies have reported that chondroitinase ABC (ChABC) or Nogo-66(1-40) antagonist peptide (NEP1-40) promote axonal growth after sp...

journal_title：Neuroscience letters

authors： Nakamae T,Tanaka N,Nakanishi K,Kamei N,Sasaki H,Hamasaki T,Yamada K,Yamamoto R,Izumi B,Ochi M

更新日期：2010-05-26 00:00:00

abstract：:Evidence from mammalian studies suggests that brain derived neurotrophic factor (BDNF) and its receptor, trk B, are upregulated in neuronal cell bodies after injury. Although fish possess neurotrophins and display rapid functional and morphological recovery after central nervous system (CNS) injury, to date few studie...

journal_title：Neuroscience letters

authors： Dalton VS,Roberts BL,Borich SM

更新日期：2009-09-25 00:00:00

abstract：:We investigated microvascular damage in areas with magnetic resonance imaging (MRI)-defined apparent diffusion coefficient reduction (ADC-R) in a rat model of thromboembolic occlusion of the middle cerebral artery. Rats received either intracarotid recombinant tissue plasminogen activator (rt-PA) or saline. Microvascu...

journal_title：Neuroscience letters

authors： Vosko MR,Busch E,Burggraf D,Bültemeier G,Hamann GF

更新日期：2003-12-26 00:00:00

abstract：:Ibotenic acid was injected in the lateral geniculate nucleus of cats to investigate the suitability of the technique in studies involving anterograde degeneration in the thalamo-cortical pathway when it is important not to damage fibres of passage at the lesion site. Small injections cause localized degeneration of ne...

journal_title：Neuroscience letters

authors： Garey LJ,Hornung JP

更新日期：1980-09-01 00:00:00

abstract：:The effects of a series of chloride transport blockers (ethacrynate, furosemide, torasemide, 4,4'-diisothiocyano-2,2'-disulfonic acid stilbene and diphenylcarboxylate) on Cl(-)-dependent L-[3H]glutamate (Glu) binding were tested in rat brain membranes, Cl-transport blockers inhibit the Ca2+/Cl(-)-induced increase in L...

journal_title：Neuroscience letters

authors： Recasens M,Pin JP,Bockaert J

更新日期：1987-02-24 00:00:00

abstract：:Viral infections are frequently found in opioid addicts, subjecting them to immune challenge. However, the effects of immune challenge on opioid withdrawal are not fully understood. In the present study, mice were intraperitoneally injected with 2mg/kg polyinosinic-polycytidylic acid (Poly I:C, a viral mimetic) for 3 ...

journal_title：Neuroscience letters

authors： Chen L,Zhai H,Lu L,Chen S,Ning Y,Wang W

更新日期：2011-01-10 00:00:00

abstract：:The circadian rhythm and dehydration-induced response of vasopressin (AVP) levels in rat cerebrospinal fluid (CSF) were studied after lesions had been made in the paraventricular (PVN) and suprachiasmatic (SCN) nuclei. The rhythmic fluctuation of AVP levels in CSF was abolished after SCN lesions, whereas lesions of th...

journal_title：Neuroscience letters

authors： Jolkkonen J,Tuomisto L,van Wimersma Greidanus TB,Riekkinen PJ

更新日期：1988-03-31 00:00:00

abstract：:A comparison has been made of the effects of carbon monoxide (CO) or nitrogen (N2) exposure on synaptic transmission in the hippocampal slice. CA1 field potentials, evoked by Schaffer collateral stimulation, were unaffected by superfusion of slices with artificial cerebral spinal fluid (ACSF) equilibrated with either ...

journal_title：Neuroscience letters

authors： Doolette DJ,Kerr DI

更新日期：1992-04-13 00:00:00

abstract：:NMDA and non-NMDA receptor-mediated components of excitatory post-synaptic current (EPSC) were studied by in situ whole-cell voltage-clamp recordings in the CA1 field of rat hippocampus. We found that the amplitudes ratio of the NMDA to the non-NMDA components can be strongly increased by blocking A1 adenosine recepto...

journal_title：Neuroscience letters

authors： Klishin A,Lozovaya N,Krishtal O

更新日期：1994-09-26 00:00:00

abstract：:Delivery of alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionate receptors (AMPARs) to the synapse is a critical factor controlling synaptic strength. It is now established that blockade of synaptic activity increases the surface expression of AMPARs. Factors modulating the delivery, insertion and expression of AMPAR...

journal_title：Neuroscience letters

authors： Wang Y,Barbaro MF,Baraban SC

更新日期：2006-06-19 00:00:00

abstract：:A late hyperpolarization (LH) which follows low level to moderate synaptic stimulation of neurons in the hippocampal formation neurons was previously shown to consist primarily of a potassium conductance. The present experiments showed that when extracellular cesium was present in order to reduce anamolous rectificati...

journal_title：Neuroscience letters

authors： Thalmann RH

更新日期：1984-04-20 00:00:00

abstract：:The potential of nitric oxide for the induction of reactive oxygen species (ROS) has been evaluated in a cerebral synaptosomal fraction. Nitric oxide (NO) was generated using S-nitroso-N-acetylpenicillamine (SNAP). NO stimulated ROS production, assayed using a fluorescent probe. This stimulation was largely inhibited ...

journal_title：Neuroscience letters

authors： Bondy SC,Naderi S

更新日期：1994-02-28 00:00:00

abstract：:The actions of acridinic acid (2,3-quinoline dicarboxylic acid), a new derivative of quinolinic acid, as an antagonist of amino acid-induced excitations are described. Acridinate, like kynurenate, in the cerebral cortex reduced the effects of all amino acids equally, but in the spinal cord was significantly less activ...

journal_title：Neuroscience letters

authors： Curry K,Magnuson DS,McLennan H,Peet MJ

更新日期：1986-05-06 00:00:00

abstract：:The effects of intrathecal injections of morphine and other opioid receptor selective drugs were tested on urinary bladder contractions in the anesthetized rat. Morphine produced dose-related inhibition of bladder motility which was abolished by naloxone. This action was also observed with mu- and delta-opioid recepto...

journal_title：Neuroscience letters

authors： Dray A,Metsch R

更新日期：1984-06-01 00:00:00

abstract：:We describe a new model of neurogenic pulmonary edema in spinal cord injured Wistar male rats. The pulmonary edema was elicited by an epidural thoracic balloon compression spinal cord lesion, performed under a low concentration of isoflurane (1.5 or 2%) in air. Anesthesia with 1.5% isoflurane promoted very severe inte...

journal_title：Neuroscience letters

authors： Sedý J,Urdzíková L,Likavcanová K,Hejcl A,Jendelová P,Syková E

更新日期：2007-08-16 00:00:00

abstract：:To investigate the capacity of the central nervous system to integrate and differentiate two different muscular fatigue states, the present study examines the changes on multi-joint movement organization following muscular fatigue of elbow extensor muscles (triceps brachii) induced by voluntary versus electrically ind...

journal_title：Neuroscience letters

authors： Huffenus AF,Forestier N

更新日期：2006-07-31 00:00:00

abstract：:The cerebellar Purkinje cell is a major site for neurosteroid formation. We have demonstrated recently that the Purkinje cell actively produces sex steroids, such as estradiol and progesterone, de novo from cholesterol only during rat neonatal life, when cerebellar cortical formation occurs. We have further demonstrat...

journal_title：Neuroscience letters

authors： Shikimi H,Sakamoto H,Mezaki Y,Ukena K,Tsutsui K

更新日期：2004-07-01 00:00:00

abstract：:The conductance increase induced by bath application of GABA has been measured in voltage-clamped stretch-receptor neurones of crayfish. A rapid conductance increase was obtained only at GABA concentrations above 3.3 X 10(-4) M. The response to lower GABA concentrations (between 10(-4) and 10(-6) M) developed slowly o...

journal_title：Neuroscience letters

authors： Deisz RA,Dose M,Lux HD

更新日期：1984-06-29 00:00:00

abstract：:The sulphur-containing acidic amino acids (SAAs) display neuroexcitatory actions similar to those of L-glutamate and are widely regarded as bona fide transmitter candidates. In this study, L-cysteine sulphinic acid, L-cysteic acid, DL-homocysteic acid and L-homocysteine sulphinic acid were investigated for their abili...

journal_title：Neuroscience letters

authors： Porter RH,Roberts PJ

更新日期：1993-05-14 00:00:00

abstract：:To determine how position sense depends on the functional state of the receptors involved, we assessed the accuracy of knee position sense before and after a moderate exercise on a cycle ergometer. Measurements were done on 32 healthy subjects with four protocols combining two tasks (intramodal: using the contralatera...

journal_title：Neuroscience letters

authors： Bouët V,Gahéry Y

更新日期：2000-08-04 00:00:00

abstract：:Single electrode voltage-clamp recording from CA3 neurons in guinea pig hippocampal slices was applied to study effects of a new GABAB antagonist, CGP 55845A, on (-)baclofen (IBac)- or gamma-aminobutyric acid (IGABA)-induced potassium (K)-currents and on inhibitory postsynaptic K-currents (K-IPSCs) recorded in the pre...

journal_title：Neuroscience letters

authors： Jarolimek W,Demmelhuber J,Bijak M,Misgeld U

更新日期：1993-05-14 00:00:00

abstract：:Interhemispheric coherence for 19 channel EEG activity collected over a three year period from 184 men and women who relaxed in a quiet, darkened chamber showed significant increased coherence between caudal temporal regions for the 11 Hz frequency band during increased (>∼8 nT) global geomagnetic activity at the time...

journal_title：Neuroscience letters

authors： Saroka KS,Caswell JM,Lapointe A,Persinger MA

更新日期：2014-02-07 00:00:00

abstract：:The purpose of this study was to measure the average anterior commissure (AC) volume of normal subjects in their 20s or 40s and to determine the effects of gender and age on AC volume. Magnetic resonance brain images were obtained for 93 people in their 20s (46 men, 47 women) and 87 in their 40s (36 men, 51 women). To...

journal_title：Neuroscience letters

authors： Choi MH,Kim JH,Yeon HW,Choi JS,Park JY,Jun JH,Lee BY,Kim HJ,Tack GR,Chung SC

更新日期：2011-08-15 00:00:00

abstract：:The effects of Sr2+ on the transmitter release at the frog neuromuscular junction were examined electrophysiologically. The nerve trunk was stimulated by paired pulses at various time intervals after replacing extracellular Ca2+ by Sr2+, the paired-pulse facilitation at the 10 ms interval was smaller than that at 20-3...

journal_title：Neuroscience letters

authors： Tanabe N,Morota A

更新日期：1999-11-19 00:00:00

abstract：:For a flickering light with two or more frequency components, the temporal envelope of the flickering light is perceived, although there is no frequency component at the frequency of the envelope. To address the processing of the temporal envelope, we compared cortical responses to the envelope of amplitude-modulated ...

journal_title：Neuroscience letters

authors： Okamoto Y,Nakagawa S

更新日期：2011-01-07 00:00:00

abstract：:A combination of immunocytochemistry with transmitter specific autoradiography at the electron microscopic level was used to identify vasoactive intestinal polypeptide (VIP)- or ACTH-containing neurons and serotoninergic nerve terminals in the suprachiasmatic (SCN) and arcuate nuclei (AN). We observed nerve terminals ...

journal_title：Neuroscience letters

authors： Kiss J,Léránth C,Halász B

更新日期：1984-02-10 00:00:00

abstract：:Clinical practice has shown that acupuncture at facial acupoints has curative effects on some visceral diseases (especially gastrointestinal diseases). However, the physiological basis has not been clarified yet. In the present study, expression of c-fos in the nucleus of the solitary tract (NTS) of rats following gas...

journal_title：Neuroscience letters

authors： Liu JH,Li J,Yan J,Chang XR,Cui RF,He JF,Hu JM

更新日期：2004-08-12 00:00:00