Development of mammalian nerve-muscle synapses in culture: lack of interference by antibodies to the neural cell adhesion molecule N-CAM and its L2/HNK-1 carbohydrate epitope.

abstract：:Cochlear hair cell loss results in the secondary loss of spiral ganglion cells (SGCs). The death of these SGCs is due to apoptosis. The E2F1-cyclin dependent kinase 1 (CDK1) pathway is believed to represent an important mechanism of neuronal cell death. However, the role of this pathway in spiral ganglion neuronal apo...

journal_title：Neuroscience letters

authors： Liu YY,Wang GP,Peng Z,Guo JY,Wu Q,Xie J,Gong SS

更新日期：2016-03-23 00:00:00

abstract：:Whole-cell recordings were obtained from respiratory neurons by applying patch-clamp techniques in the en bloc medulla of in vitro neonatal rat brainstem-spinal cord preparations. Stable voltage-clamp recordings of excitatory or inhibitory synaptic drive currents and current-clamp recordings of spike discharge of insp...

journal_title：Neuroscience letters

authors： Smith JC,Ballanyi K,Richter DW

更新日期：1992-01-06 00:00:00

abstract：:The effects of the N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists MK-801 and NBQX, respectively, on salivary secretion and retching induced by vagal stimulation were studied in decerebrate dogs. Vagal stimulation induced an increase in salivary secretion and fictive retching. Intra-4th ventricular appli...

journal_title：Neuroscience letters

authors： Furukawa N,Hatano M,Fukuda H,Koga T

更新日期：1998-12-11 00:00:00

abstract：:Several genes expressed in the suprachiasmatic nucleus (SCN) are induced by light and are candidate links in the photic entrainment pathway of the SCN's circadian clock. Since the cAMP response element binding protein (CREB) and CRE-mediated gene transcription in the SCN appears to be crucial for light-induced phase s...

journal_title：Neuroscience letters

authors： Schwartz WJ,Aronin N,Sassone-Corsi P

更新日期：2005-09-02 00:00:00

abstract：:While past research suggests that ghrelin stimulates appetite through an action on hypothalamic signaling, recent evidence indicates that the peptide acts via mesotelencephalic dopamine neurons to alter appetitive motivation. In the present study, rats were trained to operantly respond for food on a progressive ratio ...

journal_title：Neuroscience letters

authors： Weinberg ZY,Nicholson ML,Currie PJ

更新日期：2011-07-20 00:00:00

abstract：:By using intracellular deposition of horseradish peroxidase (HRP), a method has been designed for combined light and electron microscopic tracing of single fibers and synaptic terminals, belonging to physiologically characterized neurons. This technique has been successfully tested on the axon collateral systems of ca...

journal_title：Neuroscience letters

authors： Cullheim S,Kellerth JO

更新日期：1976-08-01 00:00:00

abstract：:A new dipole tracing method, based on a realistic head model, was used to determine dipole locations and vector moments of interictal convexity sharp waves recorded (with conventional EEG technique) from the right fronto-temporal region in a patient with partial complex seizures. When the dipole locations in the head ...

journal_title：Neuroscience letters

authors： Homma S,Nakajima Y,Musha T,Okamoto Y,Hagbarth KE,Blom S,Flink R

更新日期：1990-05-31 00:00:00

abstract：:Perception of limb position and motion is abnormal in Parkinson's disease (PD). Despite the fact that the processing of proprioceptive inputs is inherently temporal, most studies have assessed spatial aspects of proprioception in PD patients. Here, we use a recently described method to test whether deficits also exist...

journal_title：Neuroscience letters

authors： Fiorio M,Stanzani C,Rothwell JC,Bhatia KP,Moretto G,Fiaschi A,Tinazzi M

更新日期：2007-05-07 00:00:00

abstract：:Antipsychotic agents have typically been viewed as acting through dopaminergic targets, although mounting evidence suggests that drugs such as clozapine may act on glutamatergic systems. In order to explore the effects of clozapine on the NMDA class of glutamate receptors, oocytes expressing the NMDA receptor NR1 subu...

journal_title：Neuroscience letters

authors： Levine JB,Martin G,Wilson A,Treistman SN

更新日期：2003-08-07 00:00:00

abstract：:Electrical stimulation of the spinal tract of the trigeminal nerve at 5 Hz to elicit the trigeminal depressor response in anesthetized rabbits also causes an acute fall in ear pinna blood flow to near zero levels (from 31+/-8 to 2+/-2 kHz, n = 5, P < 0.01). This active vasoconstriction in the ear artery contrasts with...

journal_title：Neuroscience letters

authors： Yu YH,Blessing WW

更新日期：1998-10-23 00:00:00

abstract：:In an attempt to understand the change of superoxide dismutase (SOD) in tumor cells by hypoxia and hypoxia-normoxia exposure, the present study performed an in vitro investigation using rat glioma cell line in culture. Hypoxia was induced by an incubation with nitrogen gas for 15 h followed the normoxia exposure with ...

journal_title：Neuroscience letters

authors： Chang CK,Tsai CY,Lin LS,Jou SB,Liao SS,Cheng JT

更新日期：1997-08-29 00:00:00

abstract：:A traditional analysis of intra-encephalic auditory evoked potentials does not highlight the dynamical evolution of the auditory 'information' processing in neither time nor space. This work presents a method for tracing such signal evolution throughout the primary auditory pathway in the mesencephalon of adult anesth...

journal_title：Neuroscience letters

authors： Moraes MF,Del Vecchio F,Terra VC,Garcia-Cairasco N

更新日期：2000-04-21 00:00:00

abstract：:High- and low-voltage activated calcium channel currents (HVA and LVA) were inhibited by acetylcholine (10-100 microM) and baclofen (10 microM) in adult rat sensory neurons. This modulatory effect was present on dihydropyridine (nifedipine 1 microM) and/or omega-conotoxin (3.2 microM, 2-5 h incubation) insensitive com...

journal_title：Neuroscience letters

authors： Formenti A,Sansone V

更新日期：1991-10-14 00:00:00

abstract：:The sexual axis of rats can be rendered photoresponsive by testosterone implants. We have studied in these conditions whether rat pars tuberalis (PT) melatonin receptor density would be decreased after exposure to short photoperiod (SP) like as observed in long day seasonal breeders. The answer is no, but we observed ...

journal_title：Neuroscience letters

authors： Recio J,Pévet P,Míguez JM,Masson-Pévet M

更新日期：1996-08-16 00:00:00

abstract：:Methylated beta-carboline compounds are mammalian indole metabolites that we have proposed to be endogenous neurotoxins due to their structural similarity to MPP+, the active oxidized product of the dopaminergic toxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Several laboratories have demonstrated that MPP...

journal_title：Neuroscience letters

authors： Neafsey EJ,Drucker G,Raikoff K,Collins MA

更新日期：1989-11-06 00:00:00

abstract：:Considering the multiplicity of symptoms associated with multiple sclerosis (MS), there is possibility that hypocretin system function might be involved in the pathogenesis of the disease. The current study aimed to investigate the hypocretin-1 levels in cerebrospinal fluid (CSF) of MS patients in relation to differen...

journal_title：Neuroscience letters

authors： Papuć E,Stelmasiak Z,Grieb P,Paweł G,Rejdak K

更新日期：2010-04-19 00:00:00

abstract：:The serum concentration of 24S-hydroxycholesterol reflecting brain cholesterol turnover may be a possible marker for neurodegeneration and demyelination in multiple sclerosis. Serum was analyzed for cholesterol precursors and oxysterols in multiple sclerosis patients of different clinical subtypes (n=20 each subtype) ...

journal_title：Neuroscience letters

authors： Teunissen CE,Dijkstra CD,Polman CH,Hoogervorst EL,von Bergmann K,Lütjohann D

更新日期：2003-08-28 00:00:00

abstract：:Light microscopic immunohistochemistry was used to investigate the presence and distribution of chromogranin A-like immunoreactivity in the human anal canal. In the anal transitional zone (ATZ), anal duct and anal gland epithelium, a varied number of mostly elongated cells strongly stained for CGA, using an antibody d...

journal_title：Neuroscience letters

authors： Weihe E,Hörsch D,Eiden LE,Hartschuh W

更新日期：1991-09-16 00:00:00

abstract：:Patients with unilateral (n = 14) and bilateral (n = 4) herniorrhaphy participated in this study. With bilateral herniorrhaphy, at the end of the surgery, the wound was infiltrated with a solution of bupivacaine 0.5% and ketamine 0.3% on one side and a solution of bupivacaine 0.5% only, on the other. With unilateral h...

journal_title：Neuroscience letters

authors： Tverskoy M,Oren M,Vaskovich M,Dashkovsky I,Kissin I

更新日期：1996-08-30 00:00:00

abstract：:Emotions organize human and animal behaviour by automatically adjusting their actions at multiple physiological and behavioural scales. Recently, pattern recognition techniques have emerged as an important tool for quantifying the neural, physiological, and phenomenological organization of emotions in humans. Here we ...

journal_title：Neuroscience letters

authors： Nummenmaa L,Saarimäki H

更新日期：2019-02-06 00:00:00

abstract：:In complex regional pain syndrome (CRPS) many clinical symptoms suggest involvement of the central nervous system. Neuropathic pain as the leading symptom is often resistant to therapy. In the present study we investigated the analgesic efficiency of repetitive transcranial magnetic simulation (rTMS) applied to the mo...

journal_title：Neuroscience letters

authors： Pleger B,Janssen F,Schwenkreis P,Völker B,Maier C,Tegenthoff M

更新日期：2004-02-12 00:00:00

abstract：:That individual timing variability is correlated across some tasks but not others has instigated the notion of distinct timing processes, referred to as 'event' timing and 'emergent' timing for tasks with and without salient events, respectively. The delineation of the event-emergent framework owes much to the circle ...

journal_title：Neuroscience letters

authors： Huys R,Studenka BE,Zelaznik HN,Jirsa VK

更新日期：2010-03-12 00:00:00

abstract：:The autoradiographic [14C]2-deoxyglucose (2-DG) method was used to map the descending effects of midbrain reticular stimulation on the rat cervical spinal cord. The stimulation evoked consistently a defensive 'freezing' reaction as well as a large and highly localized increase in 2-DG uptake in the substantia gelatino...

journal_title：Neuroscience letters

authors： Gonzalez-Lima F

更新日期：1986-04-24 00:00:00

abstract：:Change of immunoreactive P-selectin was examined in rat brain after transient middle cerebral artery (MCA) occlusion (O) with anti-P-selectin monoclonal antibody using brain samples of sham control and after ischemia. Temporal, spatial, and cellular changes of immunohistochemical expressions of P-selectin were evaluat...

journal_title：Neuroscience letters

authors： Suzuki H,Abe K,Tojo S,Morooka S,Kimura K,Mizugaki M,Itoyama Y

更新日期：1997-06-13 00:00:00

abstract：:We investigated whether N-methyl-D-aspartate (NMDA)-induced slow current in substantia gelatinosa (SG) neurons might be of presynaptic or postsynaptic origin. Whole-cell voltage-clamp recordings were made from adult rat spinal cord slices to examine the effect of NMDA receptor upon miniature excitatory postsynaptic cu...

journal_title：Neuroscience letters

authors： Yang K,Li YQ

更新日期：2000-09-29 00:00:00

abstract：:Imagining a familiar environment is different from imagining an environmental map and clinical evidence demonstrated the existence of double dissociations in brain-damaged patients due to the contents of mental images. Here, we assessed a large sample of young and old participants by considering their ability to gener...

journal_title：Neuroscience letters

authors： Piccardi L,Nori R,Palermo L,Guariglia C,Giusberti F

更新日期：2015-08-18 00:00:00

abstract：:The Dex/CRH test is one of the most reliable neuroendocrine function tests for hypothalamic-pituitary-adrenocortical (HPA) system dysregulation in depression. Persistent overdrive of HPA system activity after successful antidepressant treatment predicts an enhanced risk for relapse of a depressive episode. As the reni...

journal_title：Neuroscience letters

authors： Baghai TC,Schule C,Zwanzger P,Minov C,Zill P,Ella R,Eser D,Oezer S,Bondy B,Rupprecht R

更新日期：2002-08-16 00:00:00

abstract：:The study examined whether the generation of the forward propulsive force (PF) during gait initiation resulted mainly from the electromyogram activity of stance ankle plantar flexor muscles (APF) which 'push' on the ground as is generally claimed in the literature. Six unilateral above-knee amputees performed a specif...

journal_title：Neuroscience letters

authors： Michel V,Do MC

更新日期：2002-06-07 00:00:00

abstract：:Stress increases associative learning and the density of dendritic spines in the hippocampus of male rats. In contrast, exposure to the same stressor impairs associative learning and reduces spine density in females. These effects in females are most evident when they are in the proestrus phase of the estrous cycle. A...

journal_title：Neuroscience letters

authors： Dalla C,Whetstone AS,Hodes GE,Shors TJ

更新日期：2009-01-02 00:00:00

abstract：:A predominant form of the GABAA/benzodiazepine receptor-Cl- channel complex is believed to consist of three different 48-55 kDa subunits (alpha, beta, gamma) with unknown stoichiometry. Plasmids containing the rat GABAA receptor cDNAs coding for alpha 1, beta 2, and gamma 2 were co-transfected, along with a plasmid en...

journal_title：Neuroscience letters

authors： Hamilton BJ,Lennon DJ,Im HK,Im WB,Seeburg PH,Carter DB

更新日期：1993-04-30 00:00:00