Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens.

abstract：:Estrogen was shown to promote neuronal survival against several neurotoxic insults including β-amyloid (Aβ). The proposed mechanism includes the activation of the mitogen activated protein kinase/extracellular signal-regulated kinase (Mapk/Erk), phosphatidylinositol 3-kinase/Akt pathways and the upregulation of antiap...

journal_title：Neuroscience letters

authors： Mateos L,Persson T,Katoozi S,Gil-Bea FJ,Cedazo-Minguez A

更新日期：2012-01-11 00:00:00

abstract：:The three tracers horseradish peroxidase (HRP), 4',6-diamidino-2-phenylindol-2HCl (DAPI) and Fast Blue (FB) differ in retrograde labeling of striato-nigral neurons. After a 24 h survival, injection of DAPI into the ventral tegmentum labeled numerous cells throughout the neostriatum, whereas an identical amount of HRP ...

journal_title：Neuroscience letters

authors： Frotscher M,Wagner A,Misgeld U

更新日期：1983-07-29 00:00:00

abstract：:In this study the effect of exogenous oxytocin and of massage-like stroking on the withdrawal latency responses to heat and mechanical nociceptive stimulation were investigated in rats. A hot-plate test and the Randall-Selitto test were used to assess the withdrawal responses. Exogenous oxytocin (0.1-1 mg/kg) and stro...

journal_title：Neuroscience letters

authors： Agren G,Lundeberg T,Uvnäs-Moberg K,Sato A

更新日期：1995-02-24 00:00:00

abstract：:Ample evidence has been reported to show a probable contribution of orexin in the central cardiovascular regulation. Although cardiovascular and respiratory centers in the brain are located close to each other and are interconnected, the possible participation of orexin in respiratory regulation has not been fully doc...

journal_title：Neuroscience letters

authors： Zhang W,Fukuda Y,Kuwaki T

更新日期：2005-09-09 00:00:00

abstract：:Procedural learning refers to the acquisition of motor skills and the practice that refines their performance. The striatum participates in this learning through a function regulated by endocannabinoid signaling and other systems. This study relates the efficiency in learning a procedural task with the AATn polymorphi...

journal_title：Neuroscience letters

authors： Ruiz-Contreras AE,Delgado-Herrera M,García-Vaca PA,Almeida-Rosas GA,Soria-Rodríguez G,Soriano-Bautista A,Cadena-Valencia J,Bazán-Frías JR,Gómez-López N,Espejel-Núñez A,Vadillo-Ortega F,Carrillo-Sánchez K,Verdín-Reyes JC,March-M

更新日期：2011-05-02 00:00:00

abstract：:Neuraxial analgesia is often provided using a mixture of local anesthetics and opioids. This combination of agents provides better pain relief and is generally associated with fewer side effects than when either drug is given alone. Local anesthetics have been shown to alter signaling of other G protein-coupled recept...

journal_title：Neuroscience letters

authors： Komai H,McDowell TS

更新日期：2007-05-18 00:00:00

abstract：:The effect of lesions on nerve growth factor receptor (NGFr) immunoreactivity (IR) in motoneurons within the mature feline trigeminal motor nucleus was investigated. Ten days following complete unilateral retrogasserian trigeminal rhizotomy including transection of the trigeminal motor root, motoneurons within the ips...

journal_title：Neuroscience letters

authors： Kullas CD,Henry MA,Westrum LE,Johnson LR,Bothwell M

更新日期：1991-05-27 00:00:00

abstract：:The coupling of muscarinic agonist receptors to guanine nucleotide-binding (G) proteins was investigated in the frontal, temporal cortices and thalamus of control and Alzheimer brains by using carbachol in competition experiments with [3H]QNB. In the presence of GppNHp, the carbachol/[3H]QNB competition binding data s...

journal_title：Neuroscience letters

authors： Warpman U,Alafuzoff I,Nordberg A

更新日期：1993-02-05 00:00:00

abstract：:In the present study, an excitatory amino acid (EAA) pathway in the spinal cord which maintains sympathetic vasomotor tone in conscious rats has been investigated. To this end, the cardiovascular effects of an intrathecally administered EAA antagonist, kynurenate (KYN), were studied in conscious rats. KYN (0.5 mumol i...

journal_title：Neuroscience letters

authors： Verberne AJ,Widdop RE,Maccarrone C,Jarrott B,Beart PM,Louis WJ

更新日期：1990-07-13 00:00:00

abstract：:Both the onset of and recovery from desensitization of three types of responses to acetylcholine in Aplysia californica occurred by biphasic kinetics. The fast component of onset recovered at a slower rate than the slow component of onset. The rates of onset and recovery were widely different when the three response t...

journal_title：Neuroscience letters

authors： Chesnut TJ,Carpenter DO

更新日期：1983-09-09 00:00:00

abstract：:The influence of chronic arthritic pain upon the levels of mRNA encoding prodynorphin (mRNADYN) in the spinal cord of rats was evaluated by use of the RNA blot technique. Rats were rendered arthritic by inoculation of the tail-base with a suspension of Mycobacterium butyricum. Three weeks post inoculation, levels of m...

journal_title：Neuroscience letters

authors： Höllt V,Haarmann I,Millan MJ,Herz A

更新日期：1987-01-02 00:00:00

abstract：:Despite much study since its discovery in 1995, the effects of orphanin FQ/nociceptin (OFQ/N), the endogenous ligand of the 'orphan' opioid receptor, on nociceptive sensitivity remain unclear. Different laboratories have variously reported hyperalgesic, analgesic, anti-analgesic or no effect of the peptide on thermal ...

journal_title：Neuroscience letters

authors： Mogil JS,Nessim LA,Wilson SG

更新日期：1999-02-19 00:00:00

abstract：:Linkage studies have implicated a broad region on chromosome 10q in Alzheimer's disease (AD). A recent genetic association study has provided evidence that polymorphism in the gene encoding alpha-3 catenin (CTNNA3, referred to previously as VR22 and also known as alpha-T catenin) may underlie linkage signals. Here, to...

journal_title：Neuroscience letters

authors： Blomqvist ME,Andreasen N,Bogdanovic N,Blennow K,Brookes AJ,Prince JA

更新日期：2004-04-01 00:00:00

abstract：:Erythropoietin (EPO) has recently been shown to have a neuroprotective effect in animal models of traumatic brain injury (TBI). However, the precise mechanisms remain unclear. Cerebral inflammation plays an important role in the pathogenesis of secondary brain injury after TBI. We, therefore, tried to analyze how reco...

journal_title：Neuroscience letters

authors： Chen G,Shi JX,Hang CH,Xie W,Liu J,Liu X

更新日期：2007-10-02 00:00:00

abstract：:The horizontal vestibulo-ocular reflex (VOR) of two groups of rats was measured. One group was bred and kept under hypergravity (HG; 2.5 g) conditions, the other group lived under normal gravity (NG; 1 g). Eye position was recorded in response to horizontal rotatory stimuli. Measurements were made under NG (1 g), and ...

journal_title：Neuroscience letters

authors： Wubbels RJ,de Jong HA

更新日期：2001-04-27 00:00:00

abstract：:We investigated the conduction velocity of motor and autonomic nerves, motor nerve to foot interosseous muscle and cervical vagus and sympathetic nerve, in streptozotocin diabetic rats (1-3 months duration of diabetes) and compared it with that of age-matched controls. In diabetic rats, the motor nerve conduction velo...

journal_title：Neuroscience letters

authors： Yamazaki Y,Karakida T,Homma S

更新日期：1990-05-18 00:00:00

abstract：:The retrograde transport of receptor-bound opiate was markedly enhanced in the vagus nerves of rats housed for 25 days in an atmosphere of ethanol vapor. This increase disappeared after 8 days of withdrawal as did the animal preference for ethanol. In contrast, the axonal transport of muscarinic receptors in sciatic n...

journal_title：Neuroscience letters

authors： Laduron PM,De Witte PA

更新日期：1987-06-26 00:00:00

abstract：:The hypothesis involving glutamate in the neuropathology of schizophrenia has attracted great interest. Several studies report dysfunctions in glutamatergic systems, including alterations in kainate and N-methyl-D-aspartate (NMDA) receptors in various areas, as well as changes in the number of glutamate uptake sites. ...

journal_title：Neuroscience letters

authors： Aparicio-Legarza MI,Cutts AJ,Davis B,Reynolds GP

更新日期：1997-08-22 00:00:00

abstract：:Face processing is unique to human beings and is likely to have special neuronal properties. We studied one of these properties, categorical representation of the face in perception processing (perception) and in memory recall processing (imagery), using the face and building stimuli. The same building-selective areas...

journal_title：Neuroscience letters

authors： Sung YW,Ogawa S

更新日期：2008-12-19 00:00:00

abstract：:Quantitative receptor autoradiography was used to study dopamine (DA) receptors in dorsal striatum and its projection regions in brains from individuals dying with Huntington's disease (HD) and controls. Heterogeneous loss of both D1 and D2 receptors was present in the striatum of early and late stage HD brains. The d...

journal_title：Neuroscience letters

authors： Richfield EK,O'Brien CF,Eskin T,Shoulson I

更新日期：1991-10-28 00:00:00

abstract：:We investigated changes in the corticospinal pattern of activity in healthy volunteers during sustained noxious and non-noxious mechanical stimulation of the first hand digit, resulting from active (self-stimulation) or passive (externally-induced) pressing against a sharp or blunted tip. The results indicate that, in...

journal_title：Neuroscience letters

authors： Fadiga L,Craighero L,Dri G,Facchin P,Destro MF,Porro CA

更新日期：2004-05-06 00:00:00

abstract：:This study examines the effect of acetylcholine (Ach) on parasympathetic vagal neurons in the dorsal motor nucleus of the vagus (DMNX). Patch-clamp techniques were utilized to examine voltage and ligand-gated currents in visualized DMNX neurons in an in vitro slice. Ach (100 microM) activated an inward current, -196.4...

journal_title：Neuroscience letters

authors： Neff RA,Hansen MK,Mendelowitz D

更新日期：1995-08-11 00:00:00

abstract：:The conversion of cellular prion protein (PrP(C)) to its protease-resistant isoform is involved in the pathogenesis of prion disease. Although PrP(C) is a ubiquitous glycoprotein that is present in various cell types, the physiological role of PrP(C) remains obscure. The present study aimed to determine whether PrP(C)...

journal_title：Neuroscience letters

authors： Watanabe T,Yasutaka Y,Nishioku T,Kusakabe S,Futagami K,Yamauchi A,Kataoka Y

更新日期：2011-06-01 00:00:00

abstract：:We observed ontogenetic changes of neuropeptide Y (NPY)-like-immunoreactivity in the terminal nerve (TN) of the chum salmon, a teleost, and the cloudy dogfish, an elasmobranch. In the chum salmon, NPY-like-immunoreactive (NPY-IR) cells first appeared in the olfactory placode of embryos at 16 days after fertilization, ...

journal_title：Neuroscience letters

authors： Chiba A,Oka S,Honma Y

更新日期：1996-07-26 00:00:00

abstract：:Bilateral, radiofrequency destruction of the hypothalamic paraventricular nucleus resulted in a pronounced depression in levels of immunoreactive (ir-) vasopressin (VP) in the medulla-pons of rats. The contents of ir-dynorphin1-17 (DYN), ir-DYN1-8 and ir-alpha-neo-endorphin (alpha-NE) therein were not, in contrast, af...

journal_title：Neuroscience letters

authors： Millan MH,Millan MJ,Herz A

更新日期：1982-12-30 00:00:00

abstract：:Spinal cord injury (SCI) leads to an increase in metabotropic glutamate receptor subtype 1 (mGluR1) immunoreactivity in the peri-lesion area. The increased expression of mGluR1 parallels the development of thermal hyperalgesia and mechanical allodynia and has been suggested to contribute to the development and mainten...

journal_title：Neuroscience letters

authors： Mills CD,Hulsebosch CE

更新日期：2002-02-15 00:00:00

abstract：:Age-related decline in plantar-surface sensitivity has been cited as one of the reasons for balance problems in older adults. This study investigated the level of plantar-surface sensitivity in older adults compared to young adults. Additionally, this study attempted to identify the onset age of advanced insensitivity...

journal_title：Neuroscience letters

authors： Perry SD

更新日期：2006-01-09 00:00:00

abstract：:Depression is among the leading causes of disability and disease burden. Recent studies point to an involvement of altered serotonin1A receptor (5-HT1AR) -mediated adult neurogenesis in depression. However, the exact underlying mechanisms remain unclear, mainly due to the complexity of the serotonergic system with its...

journal_title：Neuroscience letters

authors： Noto B,Klempin F,Alenina N,Bader M,Fink H,Sander SE

更新日期：2016-10-28 00:00:00

abstract：:The subcommissural organ (SCO) is a glandular circumventricular organ secreting glycoproteins into the cerebrospinal fluid. The SCO of 15-week-old spontaneously hypertensive rats (SHR) and of matched normotensive Wistar-Kyoto rats (WKY) was studied immunocytochemically by using an antibody against the glycoproteins se...

journal_title：Neuroscience letters

authors： Castañeyra-Perdomo A,Carmona-Calero E,Meyer G,Pérez-González H,Pérez-Delgado MM,Marrero-Gordillo N,Rodríguez S,Rodríguez EM

更新日期：1998-05-01 00:00:00

abstract：:This study was designed to assess whether phencyclidine (PCP)-induced head-twitch was antagonized by ritanserin, a selective serotonin (5-HT2) receptor antagonist, in mice and rats to confirm the involvement of 5-hydroxytryptamine (5-HT) neurons in PCP actions in comparison with 5-methoxy-N,N-dimethyltryptamine (5-MeO...

journal_title：Neuroscience letters

authors： Nabeshima T,Ishikawa K,Yamaguchi K,Furukawa H,Kameyama T

更新日期：1987-05-19 00:00:00