Differential cellular localization of oestrogen receptor immunoreactivity and oxytocin mRNA and immunoreactivity in the rat preoptic area.


:Oestrogen influences both oxytocin mRNA and peptide immunoreactivity in the preoptic area and the rat oxytocin gene contains functional oestrogen response elements. However, using combinations of immunocytochemistry and in situ hybridization for oxytocin and oestrogen receptor, we found that preoptic oxytocin neurons do not possess oestrogen receptors. This finding implies oestrogen actions on oxytocin synthesis in preoptic neurones are unlikely to be mediated directly.


Neurosci Lett


Neuroscience letters


Cruttwell CJ,Herbison AE,Bicknell RJ




Has Abstract


1995-11-17 00:00:00














  • Mismatch negativity and late discriminative negativity in sleeping human newborns.

    abstract::Event-related potentials were recorded from sleeping newborns to compare amplitudes and latencies of mismatch negativity (MMN) and late discriminative negativity (LDN) in active and quiet sleep stages. MMN and LDN were obtained in response to changes in semi-synthesized vowels from 20 healthy newborn infants. MMN and ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Martynova O,Kirjavainen J,Cheour M

    更新日期:2003-04-10 00:00:00

  • Amylin and glucose co-activate area postrema neurons of the rat.

    abstract::Glucose is an important metabolic factor controlling feeding behavior. There is evidence that physiologically relevant glucose sensors reside in the caudal hindbrain. The area postrema (AP) in particular, which has been characterized as a receptive site for the anorectic hormone amylin, may monitor blood glucose level...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Riediger T,Schmid HA,Lutz TA,Simon E

    更新日期:2002-08-09 00:00:00

  • The identification of secreted heat shock 60 -like protein from rat glial cells and a human neuroblastoma cell line.

    abstract::The intracellular stress-induced proteins provide protection against toxic insults. Here, a 60,000-Da heat shock 60 (hsp60)-like protein was detected, with five different antibodies, in conditioned media derived from rat cortical astrocytes and a human neuroblastoma cell line. Extracellular neuroblastoma hsp60-like im...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Bassan M,Zamostiano R,Giladi E,Davidson A,Wollman Y,Pitman J,Hauser J,Brenneman DE,Gozes I

    更新日期:1998-06-26 00:00:00

  • Relative enrichment of the lighter 59 kDa form of glutamic acid decarboxylase in nerve endings: an immunoblotting study in pituitary neurointermediate lobe.

    abstract::Previous studies established that glutamate decarboxylase (GAD) is present in the brain of higher vertebrates in two forms composed of the homodimeric association of two subunits 59 and 63 kDa, respectively, that were found to be structurally related. We have performed quantitative comparative immunoblotting of whole ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Henry S,Tappaz M

    更新日期:1991-10-14 00:00:00

  • Electrophysiology and morphology of a new type of cell within layer II of the rat lateral entorhinal cortex in vitro.

    abstract::Using a combination of intracellular recording and morphological techniques, we describe the properties of a new cell type within layer II of the lateral entorhinal cortex. A thick and bifurcating apical dendrite and thinner basal dendrites extended from the pyramidal shaped cell body. The axon ramified within all sup...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Empson RM,Gloveli T,Schmitz D,Heinemann U

    更新日期:1995-07-07 00:00:00

  • Perturbations in the thiol homeostasis following neonatal cerebral hypoxia-ischemia in rats.

    abstract::Changes in the thiol/disulphide status in the neonatal rat brain were evaluated after an episode of neonatal hypoxia-ischemia (HI) in 7-day-old rats. The glutathione level decreased in the post-HI period. The lowest values (43-68%) were obtained 24 h post-HI. A statistically significant difference first appeared in hi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Dafre AL,Arteni NS,Siqueira IR,Netto CA

    更新日期:2003-07-10 00:00:00

  • Effect of noise on the contrast detection threshold in visual perception.

    abstract::It has recently been shown that noise can improve the detection of stimuli in several sensory modalities. We herein investigated whether visual contrast detection sensitivity can be improved by adding a certain amount of noise. The contrast detection thresholds of a light changing brightness periodically were measured...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Sasaki H,Todorokihara M,Ishida T,Miyachi J,Kitamura T,Aoki R

    更新日期:2006-11-13 00:00:00

  • Characterization of the presynaptic calcium channels involved in glutamate exocytosis from rat hippocampal mossy fiber synaptosomes.

    abstract::Calcium antagonists inhibit both the Ca2(+)-dependent and -independent release of endogenous glutamate from intact synaptosomes. In the present study, the inhibitory potency of several different classes of calcium antagonists were determined under conditions that control for an effect of these compounds on the Ca2(+)-...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Terrian DM,Dorman RV,Gannon RL

    更新日期:1990-11-13 00:00:00

  • An apoE-derived mimic peptide, COG1410, alleviates early brain injury via reducing apoptosis and neuroinflammation in a mouse model of subarachnoid hemorrhage.

    abstract::This study investigated the neuroprotective effects of COG1410, an apoliporotein E (apoE)-derived mimic peptide, against early brain injury (EBI) after subarachnoid hemorrhage (SAH). SAH was induced in C57BL/6J mice (n=68) by endovascular perforation. Mice received intravenous injection of COG1410 (2mg/kg) or equal vo...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Wu Y,Pang J,Peng J,Cao F,Vitek MP,Li F,Jiang Y,Sun X

    更新日期:2016-08-03 00:00:00

  • Subacute toluene exposure increases DA dysfunction in the 6-OH dopamine lesioned nigrostriatal dopaminergic system of the rat.

    abstract::The potential neurotoxicity of the solvent toluene to the nigrostriatal dopaminergic system was assessed in a rat model of Parkinson's disease. Rats, 1 day after a unilateral injection of 6-hydroxydopamine (6-OH DA) into the substantia nigra, inhaled air or different concentrations of toluene (80, 300 or 1000 ppm), 6 ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Cintra A,Andbjer B,Finnman UB,Hagman M,Agnati LF,Höglund G,Fuxe K

    更新日期:1996-10-11 00:00:00

  • Induction of giant depolarizing potentials by zinc in area CA1 of the rat hippocampus does not result from block of GABAB receptors.

    abstract::The possibility that zinc (Zn2+) induces giant depolarizing potentials (GDPs) by blocking pre- and postsynaptic gamma-aminobutyric acidB (GABAB) receptors in area CA1 of rat hippocampal slices was investigated. Monosynaptic GABAA receptor-mediated fast and GABAB receptor-mediated late inhibitory postsynaptic potential...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Lambert NA,Levitin M,Harrison NL

    更新日期:1992-02-03 00:00:00

  • Association of the CR1 polymorphism with late-onset Alzheimer's disease in Chinese Han populations: a meta-analysis.

    abstract::It is well known that genetic variants play a critical role in the pathogenesis of Alzheimer's disease (AD). In 2009, a genome-wide association study (GWAS) demonstrated that a single nucleotide polymorphism (SNP), rs6656401, in complement receptor 1 (CR1) is significantly associated with late-onset Alzheimer's diseas...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,meta分析


    authors: Jin C,Li W,Yuan J,Xu W,Cheng Z

    更新日期:2012-10-03 00:00:00

  • The glutamate analogue quisqualic acid is neurotoxic in striatum and hippocampus of immature rat brain.

    abstract::To assess the neurotoxic properties of the glutamate agonist quisqualic acid (QA) in immature brain, we injected this compound (100 nmol QA/1 microliter) directly into the striatum of 7-day-old rats. QA produced neuronal necrosis and glial infiltration in 14 pups and reduced the size of the striatum and hippocampus on...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Silverstein FS,Chen R,Johnston MV

    更新日期:1986-10-30 00:00:00

  • Blockage of glucocorticoid, but not mineralocorticoid receptors prevents the persistent increase in circulating basal corticosterone concentrations following stress in the rat.

    abstract::Exposure to a single session of intense inescapable stressors results in elevations of plasma corticosterone levels selective to the trough of the circadian rhythm that last for several days after stressor cessation. In the present study, we examined whether this stress-induced alteration in the regulation of the circ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Moldow RL,Beck KD,Weaver S,Servatius RJ

    更新日期:2005-02-01 00:00:00

  • Blocking actions of picrotoxinin analogues on insect (Periplaneta americana) GABA receptors.

    abstract::Five picrotoxinin analogues were examined on GABA-gated chloride channels of an identifiable cockroach (Periplaneta americana) motor neurone (Df). Substitution of the bridgehead hydroxyl at the C-6 position of the picrotoxinin molecule by a fluorine atom (fluoropicrotoxinin) had little effect, whereas acetylation of t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Anthony NM,Holyoke CW Jr,Sattelle DB

    更新日期:1994-04-25 00:00:00

  • Preparation of an antiserum using a fusion protein produced by a cDNA for rat aromatic L-amino acid decarboxylase.

    abstract::Aromatic L-amino acid decarboxylase (AADC) decarboxylates L-DOPA and 5-hydroxytryptophan into dopamine and serotonin, respectively. Starting from a rat AADC cDNA clone isolated in our laboratory, we produced a beta-galactosidase-AADC fusion protein in E. coli. It was purified from inclusion bodies and injected into a ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Krieger M,Tillet Y,Gros F,Thibault J

    更新日期:1993-04-16 00:00:00

  • Contact heat evoked potentials as a valid means to study nociceptive pathways in human subjects.

    abstract::Contact heat evoked potentials (CHEPs) have been difficult to elicit due to slow temperature rise times. A recently developed heat-foil technology was used to elicit pain and CHEPs. Two groups of subjects were separately stimulated at the left arm with contact heat via one fast-acting (70 degrees C/s) heat-foil thermo...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Chen AC,Niddam DM,Arendt-Nielsen L

    更新日期:2001-12-01 00:00:00

  • Colocalization of GABA and glycine immunoreactivities in a subset of retinal neurons in tiger salamander.

    abstract::Alternate serial 1 micron Durcupan resin sections of tiger salamander retina were stained with antisera against GABA and glycine using postembed immunocytochemical techniques. Although the vast majority of neurons were labeled by either GABA or glycine antiserum, a small percentage of presumed amacrine cells in the in...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Yazulla S,Yang CY

    更新日期:1988-12-19 00:00:00

  • How the human auditory system treats repetition amongst change.

    abstract::Occasional repetitions embedded in a sequence of ever-changing sounds elicit a frontally negative event-related potential peaking between 100 and 200 ms from the onset of sound repetition (repetition negativity, RN). Three interpretations have been suggested for the emergence of RN: (1) RN is a mismatch negativity (MM...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Horváth J,Winkler I

    更新日期:2004-09-23 00:00:00

  • Fibroblast growth factor, epidermal growth factor and insulin exert a neuronal-like influence on acetylcholine receptors in aneurally cultured human muscle.

    abstract::Fibroblast growth factor (FGF), epidermal growth factor (EGF) and insulin added in combination to the culture medium in which normal human muscle was cultured caused a 4.0-fold (P less than 0.005) increase of the total number of nicotinic acetylcholine receptors (AChRs) and a 4.5-fold (P less than 0.001) increase in A...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Askanas V,Cave S,Gallez-Hawkins G,Engel WK

    更新日期:1985-10-24 00:00:00

  • In vitro inhibition of vasopressin release in brain by behaviorally relevant ethanol concentrations.

    abstract::We have investigated the effect of ethanol upon vasopressin (AVP) content in brain and upon in-vitro release of AVP from the rat median eminence. In-vitro ethanol concentrations (5-25 mM), comparable to behaviorally relevant blood ethanol levels, induce a substantial inhibition of AVP release from the median eminence,...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Brinton RE,Gruener R,Deshmukh P,Yamamura HI

    更新日期:1986-06-18 00:00:00

  • Inverse correlation of acetylcholinesterase (AChE) activity with the presence of neurofilament inclusions in dorsal root ganglion neurons cultured in the presence of a reversible inhibitor of AChE.

    abstract::We have previously shown that treatment of cultured dorsal root ganglion neurons (DRGN) with a highly specific, reversible acetylcholinesterase (AChE) inhibitor, BW284c51, retards neuritic outgrowth in a dose dependent manner and is accompanied by the presence of abnormal, perikaryal neurofilament (NF) inclusions in a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Dupree JL,Maynor EN,Bigbee JW

    更新日期:1995-09-01 00:00:00

  • Non-conscious neural regulation against mortality concerns.

    abstract::Social psychological studies have shown that an experience of threat such as an encounter with death-related stimuli and social exclusion results in tuning toward positive emotional information. Neuroimaging studies have also begun to uncover the neural basis of threat coping, and in this literature, the activity of t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Yanagisawa K,Kashima ES,Moriya H,Masui K,Furutani K,Nomura M,Yoshida H,Ura M

    更新日期:2013-09-27 00:00:00

  • The role of Period1 in non-photic resetting of the hamster circadian pacemaker in the suprachiasmatic nucleus.

    abstract::Non-photic stimuli, such as diurnal wheel running in rodents, phase shift the circadian clock and suppress the expression of Per1 in the suprachiasmatic nucleus (SCN). The goal of the present study was to directly decrease Per1 expression using antisense (AS) oligodeoxynucleotides to determine if such suppression prod...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Hamada T,Antle MC,Silver R

    更新日期:2004-05-20 00:00:00

  • Remacemide hydrochloride reduces cortical lesion volume following brain trauma in the rat.

    abstract::We evaluated the therapeutic effects of remacemide hydrochloride, an N-methyl-D-aspartate (NMDA) receptor-associated ionophore blocker with sodium channel blocking activity, on cortical lesion volume and memory dysfunction following parasagittal fluid-percussion brain injury in the anesthetized rat. We found that intr...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Smith DH,Perri BR,Raghupathi R,Saatman KE,McIntosh TK

    更新日期:1997-08-15 00:00:00

  • Ethanol induces rapid lipid peroxidation and activation of nuclear factor-kappa B in cerebral vascular smooth muscle: relation to alcohol-induced brain injury in rats.

    abstract::The present study was designed to test the hypothesis that acute administration of alcohol (ethanol) to primary cultured cerebral vascular smooth muscle cells will cause lipid peroxidation, inhibition of IkappaB phosphorylation, and inhibition of nuclear transcription factor-kappa B (NF-kappaB). Ethanol (10, 25, 100 m...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Altura BM,Gebrewold A,Zhang A,Altura BT

    更新日期:2002-06-07 00:00:00

  • PPARgamma stimulation promotes neurite outgrowth in SH-SY5Y human neuroblastoma cells.

    abstract::Several evidences indicate that PPARgamma stimulation promotes neuronal differentiation. However, to date, no data describe the effects of PPARgamma agonists on neurite outgrowth. Here we have evaluated the effects of pioglitazone, a synthetic PPARgamma agonist, on differentiation and neurite outgrowth in SH-SY5Y huma...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Miglio G,Rattazzi L,Rosa AC,Fantozzi R

    更新日期:2009-04-24 00:00:00

  • Estimating individual scores of inattention and impulsivity based on dynamic features of intrinsic connectivity network.

    abstract::Inattention and impulsivity are the two most important indices for evaluations of ADHD. Currently, inattention and impulsivity were evaluated by clinical scales. The intelligent evaluation of the two indices using machine learning remains largely unexplored. This paper aimed to build regression modes for inattention a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Wang XH,Xu J,Li L

    更新日期:2020-04-17 00:00:00

  • Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice.

    abstract::Although minocycline has been generally thought to have neuroprotective properties, the neuroprotective role of minocycline has not been investigated in the animal model of epilepsy. In this study, we investigated whether minocycline is neuroprotective against kainic acid (KA)-induced cell death through the caspase-de...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Heo K,Cho YJ,Cho KJ,Kim HW,Kim HJ,Shin HY,Lee BI,Kim GW

    更新日期:2006-05-08 00:00:00

  • beta-Glucan attenuates TLR2- and TLR4-mediated cytokine production by microglia.

    abstract::Microglia, the resident immune cells of the brain, are activated in response to any kind of CNS injury, and their activation is critical for maintaining homeostasis within the CNS. However, during inflammatory conditions, sustained microglial activation results in damage to surrounding neuronal cells. beta-Glucans are...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Shah VB,Williams DL,Keshvara L

    更新日期:2009-07-24 00:00:00