Differential cellular localization of oestrogen receptor immunoreactivity and oxytocin mRNA and immunoreactivity in the rat preoptic area.

Abstract:

:Oestrogen influences both oxytocin mRNA and peptide immunoreactivity in the preoptic area and the rat oxytocin gene contains functional oestrogen response elements. However, using combinations of immunocytochemistry and in situ hybridization for oxytocin and oestrogen receptor, we found that preoptic oxytocin neurons do not possess oestrogen receptors. This finding implies oestrogen actions on oxytocin synthesis in preoptic neurones are unlikely to be mediated directly.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Cruttwell CJ,Herbison AE,Bicknell RJ

doi

10.1016/0304-3940(95)12075-f

subject

Has Abstract

pub_date

1995-11-17 00:00:00

pages

89-92

issue

2

eissn

0304-3940

issn

1872-7972

pii

030439409512075F

journal_volume

200

pub_type

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