Differential cellular localization of oestrogen receptor immunoreactivity and oxytocin mRNA and immunoreactivity in the rat preoptic area.


:Oestrogen influences both oxytocin mRNA and peptide immunoreactivity in the preoptic area and the rat oxytocin gene contains functional oestrogen response elements. However, using combinations of immunocytochemistry and in situ hybridization for oxytocin and oestrogen receptor, we found that preoptic oxytocin neurons do not possess oestrogen receptors. This finding implies oestrogen actions on oxytocin synthesis in preoptic neurones are unlikely to be mediated directly.


Neurosci Lett


Neuroscience letters


Cruttwell CJ,Herbison AE,Bicknell RJ




Has Abstract


1995-11-17 00:00:00














  • Coxsackievirus B4-induced neuronal apoptosis in rat cortical cultures.

    abstract::Enterovirus infections of the central nervous system (CNS) are common and important causes of morbidity in immunocompromised children and adults. In this study we identify and characterize coxsackievirus B4-induced neuronal death. To investigate the CNS pathophysiology resulting from this viral infection, cultured rat...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Joo CH,Kim YK,Lee H,Hong H,Yoon SY,Kim D

    更新日期:2002-07-05 00:00:00

  • 8-Bromo-cAMP blocks opioid activation of a voltage-gated potassium current in isolated hippocampal neurons.

    abstract::We have previously shown that mu-selective opioid agonists activate both an inward rectifying and a voltage-gated potassium conductance in acutely dissociated non-pyramidal neurons from rat hippocampus. We now report that the opioid-activated voltage-gated potassium conductance was blocked by the membrane permeable cA...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Wimpey TL,Chavkin C

    更新日期:1992-03-16 00:00:00

  • Brain derived neurotrophic factor and trk B mRNA expression in the brain of a brain stem-spinal cord regenerating model, the European eel, after spinal cord injury.

    abstract::Evidence from mammalian studies suggests that brain derived neurotrophic factor (BDNF) and its receptor, trk B, are upregulated in neuronal cell bodies after injury. Although fish possess neurotrophins and display rapid functional and morphological recovery after central nervous system (CNS) injury, to date few studie...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Dalton VS,Roberts BL,Borich SM

    更新日期:2009-09-25 00:00:00

  • Effect of different regions of Nogo-A on the differentiation of neural progenitors.

    abstract::Nogo-A is an inhibitor of neurite outgrowth and axonal regeneration after CNS injury. Several functional regions including Nogo-66 were identified to mediate the inhibitory effect of Nogo-A. We have reported that Nogo-66 could promote neural progenitors to differentiate into glial cells. Here we exam three other regio...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Gao Y,Xiao Z,Chen B,Wang B,Han J,Zhao Y,Zhang J,Dai J

    更新日期:2009-07-24 00:00:00

  • cAMP-dependent and cAMP-independent modulation of synaptic transmission in guinea-pig superior cervical ganglion.

    abstract::RMI 12330A dose-dependently inhibits cAMP accumulation induced by PGE2 in guinea-pig superior cervical ganglion (SCG). Norepinephrine (NE) is unable to modify cAMP concentration in the same preparation. On the other hand, both PGE2 and NE block the firing discharge of guinea-pig SCG neurons elicited by electrical stim...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Borasio PG,Ferretti ME,Biondi C,Trevisani A

    更新日期:1982-10-08 00:00:00

  • Pitrazepin, a novel GABAA antagonist.

    abstract::Pitrazepin is a potent new GABA antagonist which differs from bicuculline in its chemical structure and its interaction with both [3H]muscimol and [3H]flunitrazepam binding sites, whereby the potency of pitrazepin in displacing [3H]muscimol exceeds that of bicuculline by at least a factor of 10. In physiological exper...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Gähwiler BH,Maurer R,Wüthrich HJ

    更新日期:1984-04-06 00:00:00

  • Argiotoxin636 inhibits NMDA-activated ion channels expressed in Xenopus oocytes.

    abstract::Argiotoxin636, a component of the spider venom of argiope species, was chemically synthesized together with a number of derivatives in order to analyse their blocking activity on mammalian glutamate receptors. Xenopus laevis oocytes injected with rat brain mRNA served as assay system. The results showed that argiotoxi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Draguhn A,Jahn W,Witzemann V

    更新日期:1991-11-11 00:00:00

  • Inhibition of DHCR24 increases the cisplatin-induced damage to cochlear hair cells in vitro.

    abstract::Hearing loss is a common sensory disorder that affects more than 360 million people worldwide, and is primarily caused by the loss of hair cells (HCs). Ototoxic drugs, viral infections, genetic predisposition, aging or noise all damage HCs. 3β-hydroxysteroid-Δ24 reductase (DHCR24), one enzyme in the cholesterol biosyn...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Tian KY,Chang HM,Wang J,Qi MH,Wang WL,Qiu Y,Liang K,Chen FQ,Zha DJ,Qiu JH

    更新日期:2019-07-27 00:00:00

  • A spinal projection of 5-hydroxytryptamine neurons in the lamprey brainstem; evidence from combined retrograde tracing and immunohistochemistry.

    abstract::To investigate whether there is a descending contribution to the spinal 5-hydroxytryptamine (5-HT) innervation in the lamprey, a primitive vertebrate, a study using retrograde transport of the fluorescent tracer Fast blue combined with 5-HT immunohistochemistry was conducted. Two to 4 weeks after an injection of Fast ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Brodin L,Buchanan JT,Hökfelt T,Grillner S,Verhofstad AA

    更新日期:1986-06-06 00:00:00

  • Methylation of NMDA receptor NR2B gene as a function of age in the mouse brain.

    abstract::We have previously reported that there is an up-regulation of the NR2B gene expression in the adult cortex and cultured fetal cortical neurons of mice following chronic ethanol treatment due to demethylation of cytosine residues in the NR2B gene CpG island. In the present study, we investigated the methylation pattern...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Ravindran CR,Ticku MK

    更新日期:2005-06-03 00:00:00

  • Vascular endothelial growth factor (VEGF) polymorphism is associated with treatment resistant depression.

    abstract::Antidepressive medication and electroconvulsive therapy (ECT) increase hippocampal neurogenesis by promoting expression of trophic factors, including brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF). The aims were to test for an association between the VEGF 2578 C/A polymorphism a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Viikki M,Anttila S,Kampman O,Illi A,Huuhka M,Setälä-Soikkeli E,Mononen N,Lehtimäki T,Leinonen E

    更新日期:2010-06-25 00:00:00

  • Modulatory role of acetylcholine in the rat pineal gland.

    abstract::The function of acetylcholine (ACh) in the mammalian pineal gland is unknown. To test the hypothesis that ACh exerts a modulatory role in this organ, in the present study electrophysiogical multiunit recordings were carried out in ex-vivo rat pineal glands superfused with different drugs. It was found that ACh (10(-7)...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Schenda J,Vollrath L

    更新日期:1998-09-18 00:00:00

  • Brain-wide map of projections from mice ventral subiculum.

    abstract::The hippocampal formation plays a critical role in episodic memory formation and spatial navigation. Within the hippocampus, the subiculum is considered to be a hub connecting the hippocampal formation to the remainder of the brain. There are functional differences between the dorsal and ventral part of subiculum, whi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Tang H,Wu GS,Xie J,He X,Deng K,Wang H,Xu F,Luo HR

    更新日期:2016-08-26 00:00:00

  • Identification of a GABA-containing cerebral-buccal interneuron-11 in Aplysia californica.

    abstract::The cerebral-buccal interneurons (CBIs) in Aplysia are a group of inter-ganglionic projection neurons that regulate feeding motor programs. In this study, electrophysiological and immunocytological methods were used to identify a previously uncharacterized CBI, designated CBI-11. CBI-11 is a gamma-aminobutyric acid (G...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Wu JS,Jing J,Díaz-Ríos M,Miller MW,Kupfermann I,Weiss KR

    更新日期:2003-04-24 00:00:00

  • Induction of heme oxygenase-1 (HO-1) after traumatic brain injury in the rat.

    abstract::The induction of heme oxygenase-1 (HO-1), the 32 kDa heat shock protein, was examined in the traumatized rat brain. At 24 h after either mild or severe brain injury or sham surgery, HO-1 was immunolocalized in fixed sections of brain. After mild brain injury, hemorrhage was apparent in the subarachnoid space, external...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Fukuda K,Panter SS,Sharp FR,Noble LJ

    更新日期:1995-10-20 00:00:00

  • Colocalization of GABA and glycine immunoreactivities in a subset of retinal neurons in tiger salamander.

    abstract::Alternate serial 1 micron Durcupan resin sections of tiger salamander retina were stained with antisera against GABA and glycine using postembed immunocytochemical techniques. Although the vast majority of neurons were labeled by either GABA or glycine antiserum, a small percentage of presumed amacrine cells in the in...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Yazulla S,Yang CY

    更新日期:1988-12-19 00:00:00

  • Evidence that the neuronal nitric oxide synthase inhibitor 7-nitroindazole inhibits monoamine oxidase in the rat: in vivo effects on extracellular striatal dopamine and 3,4-dihydroxyphenylacetic acid.

    abstract::The present study investigated in vivo the kinetic of the changes in rat striatal extracellular concentrations of dopamine (DA), and its monoamine oxidase (MAO)-derived metabolite 3,4-dihydroxyphenylacetic acid (DOPAC), following administration either of nitric oxide (NO) synthase (NOS) inhibitors 7-nitroindazole (7-N...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Desvignes C,Bert L,Vinet L,Denoroy L,Renaud B,Lambás-Señas L

    更新日期:1999-04-02 00:00:00

  • Duration of untreated illness as a key to early intervention in schizophrenia: A review.

    abstract::The first psychotic episode is classically viewed as a critical period which management is important in determining the long-term outcome of the schizophrenia (SCZ). For this reason, the duration of untreated illness (DUI), defined as the interval between the onset of the psychiatric disorder and the administration of...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审


    authors: Murru A,Carpiniello B

    更新日期:2018-03-16 00:00:00

  • Expression and nocturnal increase of type II iodothyronine deiodinase mRNA in rat pineal gland.

    abstract::It has been demonstrated that thyroxine deiodinating activity is present in rat pineal gland, and its activity increases significantly during the night time. We have studied whether mRNA for type II iodothyronine deiodinase is expressed in rat pineal gland and whether the nocturnal rise of pineal T4 deiodinating activ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Murakami M,Hosoi Y,Negishi T,Kamiya Y,Ogiwara T,Mizuma H,Yamada M,Iriuchijima T,Mori M

    更新日期:1997-05-09 00:00:00

  • Nitric oxide mechanism in protective effect of imipramine and venlafaxine against acute immobilization stress-induced behavioral and biochemical alteration in mice.

    abstract::Frequent and persistent stressful events caused depressive illness. Stress is an aversive stimulus which disturbs physiological homeostasis and reflects a variety of biological systems. The present study was designed to investigate the nitric oxide mechanism in the protective effect of imipramine and venlafaxine again...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Kumar A,Garg R,Gaur V,Kumar P

    更新日期:2009-12-25 00:00:00

  • Involvement of the septum in the regulation of paraventricular vasopressin neurons by the subfornical organ in the rat.

    abstract::Extracellular recordings were obtained from 58 phasically active neurosecretory neurons in the hypothalamic paraventricular nucleus (PVN) of urethane-anesthetized male rats. Of these PVN neurons, 39 exhibited an increase and 11 displayed a reduction in ongoing activity following electrical stimulation of the subfornic...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Tanaka J,Saito H,Seto K

    更新日期:1988-10-05 00:00:00

  • Protective effects of a radical scavenger edaravone on oligodendrocyte precursor cells against oxidative stress.

    abstract::Oligodendrocyte precursor cells (OPCs) play critical roles in maintaining the number of oligodendrocytes in white matter. Previously, we have shown that oxidative stress dampens oligodendrocyte regeneration after white matter damage, while a clinically proven radical scavenger, edaravone, supports oligodendrocyte repo...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Takase H,Liang AC,Miyamoto N,Hamanaka G,Ohtomo R,Maki T,Pham LD,Lok J,Lo EH,Arai K

    更新日期:2018-03-06 00:00:00

  • Dopamine- and cholecystokinin-containing neurons of the crossed mesostriatal projection.

    abstract::The projection of the substantia nigra-ventral tegmental area (SN-VTA) to the ipsilateral and contralateral caudate-putamen was studied with double-labeling fluorescence techniques in the albino rat. By combining glyoxylic acid histofluorescence with retrograde fluorescence tracers, we were able to determine that 93% ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Fallon JH,Wang C,Kim Y,Canepa N,Loughlin S,Seroogy K

    更新日期:1983-10-10 00:00:00

  • Histamine H3 receptor activation prevents dopamine D1 receptor-mediated inhibition of dopamine release in the rat striatum: a microdialysis study.

    abstract::Histamine H3 receptors (H3Rs) co-localize with dopamine (DA) D1 receptors (D1Rs) on striatal medium spiny neurons and functionally antagonize D1R-mediated responses. The intra-striatal administration of D1R agonists reduces DA release whereas D1R antagonists have the opposite effect. In this work, a microdialysis meth...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Alfaro-Rodriguez A,Alonso-Spilsbury M,Arch-Tirado E,Gonzalez-Pina R,Arias-Montaño JA,Bueno-Nava A

    更新日期:2013-09-27 00:00:00

  • Delayed visual feedback reveals distinct time scales in balance control.

    abstract::We performed an experiment in which we challenged postural stability in 12 healthy subjects by providing artificial delayed visual feedback. A monitor at eye-height presented subjects with a visual representation of the location of their center-of-pressure (COP) and they were instructed to position their COP as accura...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: van den Heuvel MR,Balasubramaniam R,Daffertshofer A,Longtin A,Beek PJ

    更新日期:2009-03-06 00:00:00

  • Connections between retrotrapezoid nucleus and nucleus tractus solitarii in cat.

    abstract::The retrotrapezoid nucleus (RTN), a part of the rostral ventrolateral medulla, is involved in the control of breathing. The mechanisms by which the RTN modulate the activity of respiratory neurons during chemoreceptor stimulation are not fully understood. This electrophysiological study performed in the cat demonstrat...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Bodineau L,Frugière A,Marlot D,Wallois F

    更新日期:2000-02-18 00:00:00

  • Reduction of glial fibrillary acidic protein-immunoreactive astrocytes in some brain areas of old hairless rhino-j mice (hr-rh-j).

    abstract::Mutations in the hairless (hr) gene of mice result in hair follicle and other epithelial defects. The hr gene is expressed at high levels in the brain where it probably participates in the survival and maintenance of some neuronal populations, but whether it also supports glial populations of the central nervous syste...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: San Jose I,García-Atares N,Pelaez B,Cabo R,Esteban I,Vega JA,Represa J

    更新日期:2001-08-24 00:00:00

  • Effect of dopamine receptor anatagonists on the calcium-dependent central function that reduces blood pressure in spontaneously hypertensive rats.

    abstract::The effects of intracerebroventricular (i.c.v.) administration of dopamine receptor antagonists on the calcium-dependent brain function that reduces blood pressure were investigated. The systolic blood pressure of spontaneously hypertensive rats (SHR; male, 13 weeks of age) was reduced following i.c.v. administration ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Sutoo D,Akiyama K

    更新日期:1999-07-16 00:00:00

  • Rundown of NMDA-receptor mediated currents is resistant to lowering intracellular [Ca2+] and is prevented by ATP in rat spinal dorsal horn neurons.

    abstract::Intracellular regulation of NMDA-receptor-mediated currents in cultured rat spinal dorsal horn neurons was investigated by means of simultaneously recording whole-cell currents and intracellular Ca2+ concentration ([Ca2+]i). During recordings in which EGTA (11 mM) was used to buffer intracellular Ca2+, NMDA currents s...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Wang YT,Pak YS,Salter MW

    更新日期:1993-07-23 00:00:00

  • Is perception of vertical impaired in individuals with chronic stroke with a history of 'pushing'?

    abstract::Post-stroke 'pushing' behaviour appears to be caused by impaired perception of vertical in the roll plane. While pushing behaviour typically resolves with stroke recovery, it is not known if misperception of vertical persists. The purpose of this study was to determine if perception of vertical is impaired amongst str...

    journal_title:Neuroscience letters

    pub_type: 杂志文章


    authors: Mansfield A,Fraser L,Rajachandrakumar R,Danells CJ,Knorr S,Campos J

    更新日期:2015-03-17 00:00:00