Phasic changes in motoneuron membrane potential during REM periods of active sleep.

Abstract:

:Most of the phasically occurring periods of rapid eye movements (REMs) of active sleep are accompanied by enhanced suppression of somatomotor activity; however, during some of the REM episodes there are muscular twitches and jerks. The membrane potential changes underlying these motor processes were examined by recording intracellularly from lumbar motoneurons in cats that were undrugged, unanesthetized and normally respiring. Summated hyperpolarizing potentials were evident during REM episodes in conjunction with a decrease in motoneuron excitability. During other episodes of REMs there occurred summated depolarizing potentials which occasionally produced action potentials. These depolarizing events were in most cases preceded by a brief period of hyperpolarization. Thus, it appears that there is inhibitory input to lumbar motoneurons during all REM periods of active sleep; in some episodes the simultaneous coactivation of excitatory input leads to depolarization of the membrane and action potential generation.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Chase MH,Morales FR

doi

10.1016/0304-3940(82)90172-0

subject

Has Abstract

pub_date

1982-12-30 00:00:00

pages

177-82

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(82)90172-0

journal_volume

34

pub_type

杂志文章
  • Dyslexics show a deviant lateralization of attentional control: a brain potential study.

    abstract::The present study compared performance and event-related brain potentials between dyslexic subjects and control subjects while they performed a spatial selective attention-shifting task. The subjects received a prestimulus cue on each trial, which indicated whether the subjects should attend to a position to the left ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.10.072

    authors: Wijers AA,Been PH,Romkes KS

    更新日期:2005-02-10 00:00:00

  • Ultrastructural demonstration of serotonin-immunoreactivity in the nervous system of an insect (Calliphora erythrocephala).

    abstract::Serotonin (5-HT) immunocytochemistry, was performed on the whole dissected nervous system of the blowfly. Employing the peroxidase-antiperoxidase technique and osmium postfixation, it was possible to examine 5-HT-immunoreactive neuronal elements first light microscopically in 25 microns sections, and, after re-embeddi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(84)90020-x

    authors: Nässel DR,Elekes K

    更新日期:1984-07-27 00:00:00

  • Visual motion perception induced by sounds in vertical plane.

    abstract::The alternation of sounds in the left and right ears induces motion perception of a static visual stimulus (SIVM: Sound-Induced Visual Motion). In this case, binaural cues were of considerable benefit in perceiving locations and movements of the sounds. The present study investigated how a spectral cue - another impor...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.05.065

    authors: Teramoto W,Manaka Y,Hidaka S,Sugita Y,Miyauchi R,Sakamoto S,Gyoba J,Iwaya Y,Suzuki Y

    更新日期:2010-08-02 00:00:00

  • BDNF as a pharmacogenetic target for antipsychotic treatment of schizophrenia.

    abstract::Antipsychotic drugs remain the mainstay of pharmacotherapy for schizophrenia. As there are large individual variations in efficacy and side-effects of antipsychotic drugs, there is a strong demand for personalized medication to treat schizophrenia. Pharmacogenetic research into antipsychotic drugs has examined a numbe...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2018.10.015

    authors: Han M,Deng C

    更新日期:2020-05-01 00:00:00

  • Cross-linking of 125I-alpha-bungarotoxin to Drosophila head membranes identifies a 42 kDa toxin binding polypeptide.

    abstract::The nicotinic acetylcholine receptor (nAChR) antagonist alpha-bungarotoxin (alpha-Btx) binds to two different classes of high affinity binding sites from the Drosophila central nervous system. We have used the bivalent reagent 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDAC) to cross-link 125I-alpha-Btx (M(r) = ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90204-k

    authors: Schloss P,Mayser W,Gundelfinger ED,Betz H

    更新日期:1992-09-28 00:00:00

  • Characterization of neuronal responses in the zona incerta of the subthalamic region of the sheep during ingestion of food and liquid.

    abstract::Single-unit recordings were made from the zona incerta of the subthalamic region of conscious sheep during ingestion. Some cells responded to ingestion and not to associated chewing, arousal or odour stimuli. Most cells changed their activity shortly after food entered the mouth and throughout ingestion, but a few res...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90362-9

    authors: Kendrick KM,Baldwin BA

    更新日期:1986-01-30 00:00:00

  • Frontal but not parietal positivity during source recollection is sensitive to episodic content.

    abstract::Remembering contextual aspects of an event (recollection) is an important function subserved by episodic memory. It has recently been shown that the electrophysiological correlates of recollection differ depending upon the type of information subjects retrieve from episodic memory. In the current study, we investigate...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.03.019

    authors: Peters J,Daum I

    更新日期:2009-05-01 00:00:00

  • Brn4 and TH synergistically promote the differentiation of neural stem cells into dopaminergic neurons.

    abstract::Neural stem cells (NSCs) are pluripotent cells capable of differentiation into dopaminergic (DA) neurons, which are the major cell types damaged in Parkinson's disease (PD). Therefore, NSCs are considered the most promising cell source for cell replacement therapy of PD. However, the poor differentiation and maturatio...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.04.019

    authors: Tan X,Zhang L,Zhu H,Qin J,Tian M,Dong C,Li H,Jin G

    更新日期:2014-06-13 00:00:00

  • Enhancement by 1-oleoyl-2-docosahexaenoyl phosphatidylcholine of long-term potentiation in the rat hippocampal CA1 region.

    abstract::We reported previously that administration of 1-oleoyl-2-docosahexaenoyl-sn-glycero-3-phosphorylcholine (ODHPC), a kind of phosphatidylcholine, enhanced discriminatory shock avoidance learning in rats. Since long-term potentiation (LTP) of the hippocampus has been suggested to be a physiological substrate of some form...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(98)00965-3

    authors: Izaki Y,Hashimoto M,Arita J

    更新日期:1999-01-29 00:00:00

  • Calcium Signaling in Schwann cells.

    abstract::In addition to providing structural, metabolic and trophic support to neurons, glial cells of the central, peripheral and enteric nervous systems (CNS, PNS, ENS) respond to and regulate neural activity. One of the most well characterized features of this response is an increase of intracellular calcium. Astrocytes at ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2020.134959

    authors: Heredia DJ,De Angeli C,Fedi C,Gould TW

    更新日期:2020-06-11 00:00:00

  • Relation between electromyogram and torque of isometric reflex contractions in man.

    abstract::Human subjects maintained isometric plantar or dorsal flexions of the ankle in a matching task. H-reflexes of different sizes were superimposed on the steady activity. The peak-to-peak amplitude of the reflexes was measured on the electromyogram (EMG) of the soleus muscle. The size of the corresponding muscle contract...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90571-5

    authors: Ruegg DG,Fluri M

    更新日期:1989-08-28 00:00:00

  • No association between Glu298Asp endothelial nitric oxide synthase polymorphism and Italian sporadic Alzheimer's disease.

    abstract::A great amount of evidence suggests that neuroinflammation may be a major pathogenetic mechanism in the pathophysiology of sporadic Alzheimer's Disease (sAD). Recently, polymorphisms in the endothelial nitric oxide synthase (NOS3) gene have been associated to late onset Alzheimer's Disease in a British population. How...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(03)00210-6

    authors: Monastero R,Cefalù AB,Camarda C,Buglino CM,Mannino M,Barbagallo CM,Lopez G,Camarda LK,Travali S,Camarda R,Averna MR

    更新日期:2003-05-08 00:00:00

  • Effect of iron and estrogen on melatonin secretion by the chicken pineal gland.

    abstract::Estrogen effects on pineal secretion of melatonin are controversial. Some feel that estrogen inhibits melatonin output in vitro but not in vivo. Melatonin levels vary with the age in chickens where circulating estrogen levels also vary. Laying hens have minimal melatonin levels and maximal serum iron concentrations. T...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90836-a

    authors: Pablos MI,Agapito MT,Recio JM,Pérez-Gallardo L,Córdova MD,Mori JO

    更新日期:1993-09-03 00:00:00

  • Dehydroepiandrosterone sulfate inhibition of catecholamine secretion from bovine adrenal chromaffin cells.

    abstract::Dehydroepiandrosterone sulfate (DHEAS) dose-dependently inhibited [3H]norepinephrine (NE) secretion and the corresponding [Ca2+]i rise induced by the nicotinic receptor agonist 1,1-dimethyl-4-phenylpoperazimium (DMPP) in bovine chromaffin cells. DHEAS at 10 microM, the physiological concentration in human serum, signi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(96)12350-8

    authors: Liu PS,Lin MK,Hsieh HL

    更新日期:1996-02-09 00:00:00

  • NOD2 mediates isoflurane preconditioning-induced protection of myocardial injury.

    abstract::Anesthetic cardioprotection reduces myocardial infarct size following ischemia-reperfusion injury. However, the underlying mechanisms that drive ischemia-reperfusion injury in cardiomyocytes remain unclear. In this study, we report that isoflurane, a commonly used inhaled anesthetic, can protect cardiomyocytes from an...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.11.031

    authors: Yang C,Jiao Y,Yan N,Wu B,Ren Y,Li H,Sun J,Gao J

    更新日期:2017-01-10 00:00:00

  • Reticular premotor neurons projecting to both facial and hypoglossal nuclei receive trigeminal afferents in rats.

    abstract::The distribution of premotor neurons projecting to motor nuclei of both the VIIth (VII) and XIIth (XII) nerves was examined in the pontomedullary reticular formation (RF) of the rat by using retrograde double labeling. After injection of two different tracers in the VII and the XII, most of the double labeled neurons ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)02150-4

    authors: Dauvergne C,Pinganaud G,Buisseret P,Buisseret-Delmas C,Zerari-Mailly F

    更新日期:2001-09-28 00:00:00

  • Butyrate, neuroepigenetics and the gut microbiome: Can a high fiber diet improve brain health?

    abstract::As interest in the gut microbiome has grown in recent years, attention has turned to the impact of our diet on our brain. The benefits of a high fiber diet in the colon have been well documented in epidemiological studies, but its potential impact on the brain has largely been understudied. Here, we will review eviden...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2016.02.009

    authors: Bourassa MW,Alim I,Bultman SJ,Ratan RR

    更新日期:2016-06-20 00:00:00

  • Event-related potentials during exposure to aversion and its anticipation: the moderating effect of intolerance of uncertainty.

    abstract::The aim of the present study was to investigate the moderating effect of intolerance of uncertainty (IU) on exposure to aversion and its anticipation using event-related potentials (ERPs). Sixteen subjects high in IU and 16 subjects low in IU underwent an affective cueing paradigm where a warning cue signaled the vale...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.11.054

    authors: Gole M,Schäfer A,Schienle A

    更新日期:2012-01-24 00:00:00

  • Rho kinase inhibitor Y-27632 promotes neuronal differentiation in mouse embryonic stem cells via phosphatidylinositol 3-kinase.

    abstract::Rho kinase (ROCK) regulates the functions of several target proteins via its kinase activity. Therefore, ROCK activity inhibition may provide new possibilities of controlling the in vitro neuronal differentiation of embryonic stem (ES) cells. When we investigated the effects of the ROCK inhibitor Y-27632 on ES cell di...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.01.022

    authors: Kamishibahara Y,Kawaguchi H,Shimizu N

    更新日期:2016-02-26 00:00:00

  • MDM2 antagonism by nutlin-3 induces death in human medulloblastoma cells.

    abstract::A critical component of the cellular stress response, the p53 tumor suppressor protein must be functional for many cancer therapies to be effective. Adjuvant therapies that augment p53 function are predicted to sensitize tumor cells to cancer therapies that rely upon p53 for their efficacy. Of those strategies current...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.02.022

    authors: Ghassemifar S,Mendrysa SM

    更新日期:2012-03-28 00:00:00

  • Two types of A-current differing in voltage-dependence are expressed by neurons of the rat neostriatum.

    abstract::Transient potassium currents of the A type are thought to be important in a number of physiological processes of excitable cells, including spike repolarization and synaptic integration. This functional diversity may reflect the contribution of distinct subtypes of A channel to cellular behavior. Using the whole-cell ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90122-5

    authors: Surmeier DJ,Bargas J,Kitai ST

    更新日期:1989-09-11 00:00:00

  • Retrograde labeling of striato-nigral neurons in the rat by three different tracers.

    abstract::The three tracers horseradish peroxidase (HRP), 4',6-diamidino-2-phenylindol-2HCl (DAPI) and Fast Blue (FB) differ in retrograde labeling of striato-nigral neurons. After a 24 h survival, injection of DAPI into the ventral tegmentum labeled numerous cells throughout the neostriatum, whereas an identical amount of HRP ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(83)90025-3

    authors: Frotscher M,Wagner A,Misgeld U

    更新日期:1983-07-29 00:00:00

  • Sorbitol accumulation and transmembrane efflux in osmotically stressed JS1 schwannoma cells.

    abstract::Sorbitol accumulation and transmembrane efflux in JS1 schwannoma cells were examined during osmotic stress in the presence of a sorbitol dehydrogenase (SD) inhibitor and following return to iso-osmotic conditions. SD inhibition promoted sorbitol accumulation under hyperglycemic and/or hyperosmotic conditions, and sorb...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00416-3

    authors: Mizisin AP,Li L,Calcutt NA

    更新日期:1997-06-20 00:00:00

  • Isolated axons of Wlds mice regrow centralward.

    abstract::We have conjectured that axons embody a post transcriptional sprouting programme repressed by mature Schwann cells. Injured nerves of Wld(s) mice neither degenerate nor regenerate for several weeks but axons do regrow if the resident cells of the distal stump are destroyed. To test our hypothesis we made an extended c...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00369-9

    authors: Iñiguez A,Alvarez J

    更新日期:1999-06-18 00:00:00

  • Different growth patterns of two adjacent glomeruli responsible for sex-pheromone processing during postembryonic development of the cockroach Periplaneta americana.

    abstract::In many insect species, sex pheromone is processed by specific, enlarged glomeruli in the antennal lobes of males. In the male American cockroach, two closely located glomeruli (A and B) are responsible for processing the major pheromone components (periplanone-A and -B, respectively), and these collectively form the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.07.012

    authors: Nishino H,Yoritsune A,Mizunami M

    更新日期:2009-10-25 00:00:00

  • Preservation of dopamine release in the denervated striatum.

    abstract::Dopamine metabolism and release were determined in the striata of rats sustaining varying damage to the nigrostriatal dopamine (DA) projection. DA metabolism, inferred from concentrations of dihydroxy-phenylacetic acid (DOPAC) or homovanillic acid (HVA), decreased with DA denervation of more than 20%. Dopamine release...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90400-x

    authors: Altar CA,Marien MR

    更新日期:1989-01-30 00:00:00

  • Neural actions of several substance P antagonists in the rat spinal cord.

    abstract::Four substance P (SP) antagonists were tested on anaesthetized rats, by injecting 8 microgram amounts into the spinal cord (T8-T9), and by observing their effects on the hypothalamo-neurohypophysial responses to a presumably painful stimulus, the superfusion of the hepatic portal vein with 1 microM bradykinin. Only tw...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(83)90444-5

    authors: Stoppini L,Baertschi AJ,Mathison R,Barja F

    更新日期:1983-06-30 00:00:00

  • Induction of heme oxygenase-1 (HO-1) after traumatic brain injury in the rat.

    abstract::The induction of heme oxygenase-1 (HO-1), the 32 kDa heat shock protein, was examined in the traumatized rat brain. At 24 h after either mild or severe brain injury or sham surgery, HO-1 was immunolocalized in fixed sections of brain. After mild brain injury, hemorrhage was apparent in the subarachnoid space, external...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)12042-3

    authors: Fukuda K,Panter SS,Sharp FR,Noble LJ

    更新日期:1995-10-20 00:00:00

  • D-cycloserine enhances both intrinsic excitability of CA1 hippocampal neurons and expression of activity-regulated cytoskeletal (Arc) protein.

    abstract::The interaction of NMDA receptor (NMDAR) activation and other mechanisms regulating neuronal excitability have not been thoroughly described. While excess activation of NMDARs results in excitotoxicity, partial activation of NMDARs by d-cycloserine (DCS) is nootropic, enhancing both acquisition and extinction of memor...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.04.035

    authors: Donzis EJ,Thompson LT

    更新日期:2014-06-13 00:00:00

  • Neural activation in response to the two sides of emotion.

    abstract::Emotions are at the core of human cognition and behavior. Traditionally, emotions have been classified dichotomously as being either positive or negative. However, recent behavioral research (An et al., 2017) suggests that emotions contain both positivity and negativity. The current work investigated neural correlates...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2018.07.011

    authors: An S,Han X,Wu B,Shi Z,Marks M,Wang S,Wu X,Han S

    更新日期:2018-09-25 00:00:00