Abstract:
:A quantitative analysis of cytochrome oxidase (CO) activity in histochemically stained sections of rat brain was developed using tissue standards and computerized image processing. Standards of brain paste containing known amounts of CO were cryosectioned and stained under the same conditions as brain sections. The gray levels of the stain were converted to units of CO activity using a calibration curve derived from densitometric analysis of the standards. The technique yields reproducible quantitative values, has the superior anatomical resolution of histochemistry, and is compatible with autoradiography.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Gonzalez-Lima F,Garrosa Mdoi
10.1016/0304-3940(91)90943-nsubject
Has Abstractpub_date
1991-02-25 00:00:00pages
251-3issue
2eissn
0304-3940issn
1872-7972pii
0304-3940(91)90943-Njournal_volume
123pub_type
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