Immobilisation stress induces a paradoxical sleep rebound in rat.

Abstract:

:An immobilisation stress (IS) of 2 h applied to rats at the beginning of the dark period (12 h), i.e. when the animals are more active, induces during the 10 consecutive h a significant rebound (+92%) of paradoxical sleep (PS) while slow-wave sleep state (SWS) is poorly affected. Two h of sleep deprivation, also applied at the beginning of the dark period and realized either by the platform technique or by maintaining the animals awake with gentle handling, do not affect significantly subsequent SWS and PS. Finally, when repetitive IS are inflicted to the animals (one IS of 2 h every 3 days) an attenuation of the PS rebound is observed. These data suggest that a qualitative aspect of the waking state as in an intense stressful situation might be the source of a hormonal process inducing a PS excess.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Rampin C,Cespuglio R,Chastrette N,Jouvet M

doi

10.1016/0304-3940(91)90532-x

subject

Has Abstract

pub_date

1991-05-27 00:00:00

pages

113-8

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(91)90532-X

journal_volume

126

pub_type

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