Stability of [D-Trp11]-neurotensin to rat brain peptidases.

abstract：:CREATE (Consider, Read, Elucidate hypotheses, Analyze and interpret data, Think of the next Experiment) is a pedagogical approach for teaching and learning science through the rigorous analysis of primary scientific literature. This mini-review focuses on the tools, assignments, and in-class activities by which this s...

journal_title：Neuroscience letters

authors： Pugh-Bernard A,Kenyon KL

更新日期：2021-01-18 00:00:00

abstract：:In all mammals so far investigated the occurrence of ponto-geniculo-occipital (PGO) waves precedes the onset and maintenance of desynchronized (D) sleep. As unitary electrographic events, PGO waves provide an index for quantitative evaluation of physiological D sleep or the D sleep-like state evoked by centrally admin...

journal_title：Neuroscience letters

authors： Baghdoyan HA,Lydic R,Callaway CW,Hobson JA

更新日期：1987-12-04 00:00:00

abstract：:The mental rotation (MR) task is defined as a discrimination task between mirror-reversed images involving discrepancy in angular orientation. Various studies have shown that the MR task likely causes mental imagery, that is, visual and/or motor imagery, depending on stimulus types. When figures of rotated hands are p...

journal_title：Neuroscience letters

authors： Meng S,Oi M,Sekiyama K,Saito H

更新日期：2016-08-03 00:00:00

abstract：:Localization of the epileptogenic zone (EZ) is an important issue in epileptology, even though there is not a unique definition of the epileptic focus. By using complex network analysis of electrocorticographic (ECoG) data we identify three singular areas in the temporal lobe of epileptic patients, the node with highe...

journal_title：Neuroscience letters

authors： Ortega GJ,Sola RG,Pastor J

更新日期：2008-12-12 00:00:00

abstract：:During hibernation the body temperature of the golden-mantled ground squirrel, Spermophilus lateralis, may drop below 5 degrees C for a few hours to a week or more. Animals cycle between euthermia and deep hibernation many times over the course of the hibernation season. Expression of the transcription factor c-fos in...

journal_title：Neuroscience letters

authors： Bitting L,Sutin EL,Watson FL,Leard LE,O'Hara BF,Heller HC,Kilduff TS

更新日期：1994-01-03 00:00:00

abstract：:Limited work has been done to investigate the molecular mechanisms behind the process of demyelination and remyelination that occurs in response to chronic nerve compression (CNC) injury. In the present study, we investigated the expression of the transcription factors krox-20 and c-jun, positive and negative regulato...

journal_title：Neuroscience letters

authors： Pham K,Nassiri N,Gupta R

更新日期：2009-11-13 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by amyloid plaques, neuritic degenerations, disturbed glutamatergic neurotransmission and a peculiar inflammatory response. Diffuse plaques develop into neuritic plaques when neurites undergo degeneration in the plaque area. Hyperphosphorylation of tau proteins is a major step...

journal_title：Neuroscience letters

authors： Hüll M,Eistetter J,Fiebich BL,Bauer J

更新日期：1999-02-12 00:00:00

abstract：:Evidence, based on voltage-clamp and current-clamp recording, is presented for endogenous receptors for vasoactive intestinal polypeptide (VIP) on the cell membrane of the Xenopus oocyte. At normal resting potential a hyperpolarisation is produced by VIP, associated with an increase in K+ conductance. The response is ...

journal_title：Neuroscience letters

authors： Reale V,Ashford ML,Barnard EA

更新日期：1987-12-16 00:00:00

abstract：:Sorbitol accumulation and transmembrane efflux in JS1 schwannoma cells were examined during osmotic stress in the presence of a sorbitol dehydrogenase (SD) inhibitor and following return to iso-osmotic conditions. SD inhibition promoted sorbitol accumulation under hyperglycemic and/or hyperosmotic conditions, and sorb...

journal_title：Neuroscience letters

authors： Mizisin AP,Li L,Calcutt NA

更新日期：1997-06-20 00:00:00

abstract：:The blood-brain barrier (BBB) plays an important role in controlling the passage of molecules from the blood to the extracellular fluid environment of the brain. An immortalised rat brain endothelial cell line (GPNT) was used to investigate the mechanisms underlying dexamethasone-induced decrease in paracellular perme...

journal_title：Neuroscience letters

authors： Romero IA,Radewicz K,Jubin E,Michel CC,Greenwood J,Couraud PO,Adamson P

更新日期：2003-06-26 00:00:00

abstract：:To investigate whether any specific requirement for extracellular Ca2+ exists in the control synaptic vesicle retrieval, we examined the ability of the divalent cation Ba2+ to substitute for Ca2+ in both vesicle exocytosis and endocytosis. Ba2+ stimulated glutamate release from rat cerebrocortical synaptosomes. Ba2+-e...

journal_title：Neuroscience letters

authors： Cousin MA,Robinson PJ

更新日期：1998-08-28 00:00:00

abstract：:It is generally assumed that the majority of substance P (SP)-containing afferents are also immunoreactive for calcitonin gene-related peptide (CGRP). In order to determine whether this is also the case in articular afferents where the contents of these peptides are low, we carried out a double labeling study using Fa...

journal_title：Neuroscience letters

authors： Tamura R,Hanesch U,Schmidt RF,Kumazawa T,Mizumura K

更新日期：1998-09-18 00:00:00

abstract：:The morphology and spatial distribution of terminals emitted by corticothalamic axons originating from the rat motor cortex (as defined by intracortical microstimulations) were studied using Phaseolus vulgaris leucoagglutinin (PHA-L) as an anterograde tracer. After PHA-L injection in the face, forelimb or hindlimb mot...

journal_title：Neuroscience letters

authors： Rouiller EM,Liang FY,Moret V,Wiesendanger M

更新日期：1991-04-15 00:00:00

abstract：:The relation between phantom limb pain (PLP) and the movement representation of a phantom limb remains controversial in several areas of neurorehabilitation, although there are a few studies in which the representation of phantom limb movement was precisely evaluated. We evaluated the structured movement representatio...

journal_title：Neuroscience letters

authors： Osumi M,Sumitani M,Wake N,Sano Y,Ichinose A,Kumagaya S,Kuniyoshi Y,Morioka S

更新日期：2015-09-25 00:00:00

abstract：:Freshly isolated or culture-expanded human umbilical cord blood mononuclear cells (CBMNCs) have been known to express neural phenotypes in vitro and to differentiate into neural cells and improve neurological function recovery after being administrated into rodent models of neurological diseases. However, the mechanis...

journal_title：Neuroscience letters

authors： Fan CG,Zhang QJ,Tang FW,Han ZB,Wang GS,Han ZC

更新日期：2005-06-03 00:00:00

abstract：:Nitric oxide (NO) exerts cytotoxic effects on various cells including neuronal cells. Glial NO production, mediated via induction of inducible NO synthase (iNOS), enhances neurotoxicity associated with the N-methyl-D-aspartate (NMDA) receptor. The present study examined whether nicotinamide, an inhibitor of poly (ADP-...

journal_title：Neuroscience letters

authors： Fujimura M,Tominaga T,Yoshimoto T

更新日期：1997-06-06 00:00:00

abstract：:Motoneuron death induced by sciatic nerve transection in neonatal rats has been related to induction of the neuronal isoform of nitric oxide synthase (nNOS), a diaphorase of which one of the cofactors is nicotinamide adenine dinucleotide phosphate (NADPH). We transected the sciatic nerve of neonatal rats (P2) and exam...

journal_title：Neuroscience letters

authors： Rogério F,Teixeira SA,de Souza Queiroz L,De Nucci G,Langone F

更新日期：2001-07-13 00:00:00

abstract：:The effect of intracerebroventricular (i.c.v.) injection of brain natriuretic peptide (BNP), a novel peptide purified from the porcine brain, on arginine vasopressin (AVP) secretion was studied in conscious, unrestrained rats and was compared with that of atrial natriuretic polypeptide (ANP). I.c.v. administration of ...

journal_title：Neuroscience letters

authors： Yamada T,Nakao K,Itoh H,Shirakami G,Kangawa K,Minamino N,Matsuo H,Imura H

更新日期：1988-12-19 00:00:00

abstract：:We examined the intracellular Ca2+ ([Ca2+]i) elevation evoked by GABA in an 8-day embryonic chick brainstem slice using a Ca imaging technique with Ca green-1 AM. When small quantities of GABA were pressure-ejected on the surface of the slice, the [Ca2+]i elevation was clearly detected. The GABA-induced [Ca2+]i elevat...

journal_title：Neuroscience letters

authors： Momose-Sato Y,Kinoshita M,Sato K

更新日期：2007-01-03 00:00:00

abstract：:The motor activity of the rat bladder elicited by transmural electrical stimulation was abolished in the presence of 200 nM tetrodotoxin but not of 1 microM atropine plus 3.4 microM guanethidine. Tissue preincubation with 20 microM, alpha, beta-methylene ATP reduced but did not obliterate the electrically-induced moto...

journal_title：Neuroscience letters

authors： Acevedo CG,Lewin J,Contreras E,Huidobro-Toro JP

更新日期：1990-05-31 00:00:00

abstract：:When locally infused, the potent vasoconstrictor, endothelin-1 (ET-1) produces partial ischemic damage in many regions of the brain, including the hippocampus. The hippocampus is known for a high density of glucocorticoid receptors and for the potent actions of stress and corticosterone to modulate function. The curre...

journal_title：Neuroscience letters

authors： Faraji J,Lehmann H,Metz GA,Sutherland RJ

更新日期：2009-10-25 00:00:00

abstract：:Several evidences indicate that PPARgamma stimulation promotes neuronal differentiation. However, to date, no data describe the effects of PPARgamma agonists on neurite outgrowth. Here we have evaluated the effects of pioglitazone, a synthetic PPARgamma agonist, on differentiation and neurite outgrowth in SH-SY5Y huma...

journal_title：Neuroscience letters

authors： Miglio G,Rattazzi L,Rosa AC,Fantozzi R

更新日期：2009-04-24 00:00:00

abstract：:It is known that maternal deprivation induces hippocampal damage in the developing brains. In the present study, we examined the effects of melatonin on maternal deprivation-induced hippocampal damage both during and after stress-hyporesponsive period (SHRP). Hippocampal damage was examined by cresyl violet staining a...

journal_title：Neuroscience letters

authors： Tugyan K,Uysal N,Ozdemir D,Sonmez U,Pekcetin C,Erbil G,Sonmez A

更新日期：2006-05-01 00:00:00

abstract：:A tight coupling between lexico-semantic access and motor control has been established on the basis of neuropsychological, neurophysiological, and behavioral evidence. For example, sensory and motor cortices have been shown to be active when subjects listen to words denoting bodily actions. Kinematic analyses of subje...

journal_title：Neuroscience letters

authors： Shiller DM,Bourguignon N,Frak V,Nazir T,Cadoret G,Robert M,Lemay M

更新日期：2013-10-25 00:00:00

abstract：:The streptozotocin (STZ)-induced diabetes model is widely used for the induction of neuropathy in the rat. In this model, diabetic animals often display chronic illness, which raises objections not only on ethical but also on scientific grounds. In this study, the investigators set out to determine the impact of bodyw...

journal_title：Neuroscience letters

authors： Hoybergs YM,Biermans RL,Meert TF

更新日期：2008-05-02 00:00:00

abstract：:FOXP2, the first gene known to be involved in the development of speech and language, can be considered to be, a priori, a candidate gene in schizophrenia, given the mounting evidence that the underlying core deficit in this disease could be a failure of structures relevant to normal language processing. To investigat...

journal_title：Neuroscience letters

authors： Španiel F,Horáček J,Tintěra J,Ibrahim I,Novák T,Čermák J,Klírová M,Höschl C

更新日期：2011-04-15 00:00:00

abstract：:Estrogen was shown to promote neuronal survival against several neurotoxic insults including β-amyloid (Aβ). The proposed mechanism includes the activation of the mitogen activated protein kinase/extracellular signal-regulated kinase (Mapk/Erk), phosphatidylinositol 3-kinase/Akt pathways and the upregulation of antiap...

journal_title：Neuroscience letters

authors： Mateos L,Persson T,Katoozi S,Gil-Bea FJ,Cedazo-Minguez A

更新日期：2012-01-11 00:00:00

abstract：:Freezing is one of the most widely recognized defensive reactions to approaching threats in animals. Here we tested whether the same stimuli can elicit freeze-like responses in healthy humans as well. We used a modified version of the two-frame apparent motion paradigm, in which both size and location of a stimulus wi...

journal_title：Neuroscience letters

authors： Sagliano L,Cappuccio A,Trojano L,Conson M

更新日期：2014-02-21 00:00:00

abstract：:To elucidate the relationship between glutamatergic and dopaminergic transmissions, the effects of antisense oligodeoxynucleotide (aODN) to mRNA of NR1 subunit of N-methyl-D-aspartate (NMDA) receptors on the expression of dopamine D(2) receptors (DRD(2)) were examined. Rats received continuous intracerebroventricular ...

journal_title：Neuroscience letters

authors： Murata M,Suzuki M,Tanaka K,Tajiri K,Emori K,Kurachi M

更新日期：2002-12-19 00:00:00

abstract：:In vitro quantitative autoradiography was used to visualize nicotinic receptors in large cryosections of human brain hemispheres. Sections 80 microns thick of human brain hemispheres were incubated with (-)-[3H]nicotine and the distribution of nicotinic receptors in human brain was studied. Increasing numbers of nicot...

journal_title：Neuroscience letters

authors： Adem A,Nordberg A,Jossan SS,Sara V,Gillberg PG

更新日期：1989-07-03 00:00:00