Co-release of acetylcholine, glutamate and taurine from synaptosomes of Torpedo electric organ.

abstract：:The present study examined perception of individual finger forces during multi-finger force production tasks. In an ipsilateral force matching paradigm, 12 healthy subjects were instructed to produce a reference force pre-determined at 30% MVC of involved fingers (varying from 1 to 4 fingers, visual feedback of total ...

journal_title：Neuroscience letters

authors： Li S

更新日期：2006-12-06 00:00:00

abstract：:Several lines of evidence indicate that the histaminergic (HA) system is important for wakefulness and behavioral state regulation. We investigated the hypothesis that age-related changes in HA system occur which may be related to decreased alertness in aging. Although histidine decarboxylase mRNA levels did not chang...

journal_title：Neuroscience letters

authors： Terao A,Steininger TL,Morairty SR,Kilduff TS

更新日期：2004-01-23 00:00:00

abstract：:Kynurenic acid (KYNA) is an antagonist of (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptors and it blocks the glycine site of the NMDA receptor preferentially (IC50 = 7.9 microM). KYNA is produced endogenously by transamination of its precursor L-kynurenin...

journal_title：Neuroscience letters

authors： Scharfman HE,Hodgkins PS,Lee SC,Schwarcz R

更新日期：1999-10-22 00:00:00

abstract：:The medial prefrontal cortex (mPFC) is thought to exert inhibitory control over stress-induced activation of the amygdala and neurocognitive effects. As evidence to support this, we examined how exposure to either a brief or prolonged stress affected on amygdalar c-Fos levels and recognition memory of animals with mPF...

journal_title：Neuroscience letters

authors： Park JC,Jeon YJ,Kim JJ,Cho J,Choi DH,Han JS

更新日期：2020-09-14 00:00:00

abstract：:Exposure to alcohol in utero has been associated with hypothyroidism and a variety of developmental defects characteristic of thyroid dysfunction. The present work examined whether these abnormalities could be reversed in infant rats treated with thyroid hormones. Subjects were offspring of dams which were on the foll...

journal_title：Neuroscience letters

authors： Gottesfeld Z,Silverman PB

更新日期：1990-02-05 00:00:00

abstract：:Approximately 8.5% of the unmyelinated and 2.5% of the myelinated primary afferent axons in lumbar dorsal roots of normal rats are immunostained for glutamate. Thus unmyelinated fibers are the predominantly immunostained population under the conditions of our experiments. The mean size of the unmyelinated fibers is gr...

journal_title：Neuroscience letters

authors： Westlund KN,McNeill DL,Coggeshall RE

更新日期：1989-01-02 00:00:00

abstract：:The binding of the lectin soybean agglutinin (SBA) to the olfactory system of both the rat and mouse was investigated histochemically. SBA bound to fibers in the accessory olfactory nerve and to glomeruli in the accessory olfactory bulb. In addition, SBA binding sites were present in some, but not all, glomeruli in th...

journal_title：Neuroscience letters

authors： Key B,Giorgi PP

更新日期：1986-08-29 00:00:00

abstract：:Somatostatin (SRIF) release from fetal rat cortical cells was stimulated by exposure to 10(-5) M N-methyl-D-aspartate (NMDA) (250 +/- 20% of basal at 96 h). A similar but much less potent effect was seen with kainate (KA) but not with quisqualate (Q) which inhibited SRIF release (KA 150 +/- 13%, Q 65 +/- 18% of basal ...

journal_title：Neuroscience letters

authors： Ham J,Rickards C,Scanlon M

更新日期：1991-08-19 00:00:00

abstract：:The intervibrissal fur-evoked activity in the rat somatosensory cortex was investigated using high-resolution optical imaging with a voltage-sensitive dye. The optical imaging revealed that the intervibrissal fur representation forms a U-shaped band around the borders of the posteromedial barrel subfield (PMBSF), and ...

journal_title：Neuroscience letters

authors： Takashima I,Kajiwara R,Iijima T

更新日期：2005-06-24 00:00:00

abstract：:The aim of this study was to clarify whether 12-lipoxygenase (12-LOX) activation was involved in reactive oxygen species (ROS) generation, extensive poly(ADP-ribose) polymerase (PARP) activation and neuronal death induced by glucose-deprivation, followed by glucose-reload (GD/R). The decrease of neuronal viability and...

journal_title：Neuroscience letters

authors： Nagasawa K,Kakuda T,Higashi Y,Fujimoto S

更新日期：2007-12-18 00:00:00

abstract：:Most fibres in adult muscles are derived from secondary myotubes which form around an earlier developing population of primary myotubes. We examined embryonic rat IVth lumbrical muscles at a stage when most secondary myotubes were less than 24 h old, in order to study their acquisition of synaptic terminals. Single ne...

journal_title：Neuroscience letters

authors： Duxson MJ,Ross JJ,Harris AJ

更新日期：1986-11-11 00:00:00

abstract：:Super-resolution microscopy techniques offer subdiffraction limited resolution that is two- to ten-fold improved compared to that offered by conventional confocal microscopy. This breakthrough in resolution for light microscopy has contributed to new findings in neuroscience and synapse biology. This review will focus...

journal_title：Neuroscience letters

authors： Badawi Y,Nishimune H

更新日期：2020-01-10 00:00:00

abstract：:In freshly dissociated viable cells of early postnatal mouse cerebellum, O1 antigen-positive oligodendrocytes have been eliminated by complement dependent immunocytolysis. Before seeding residual cells in culture, O4 antigen-positive cells were immunolabeled by O4 antibody which had been directly conjugated with rhoda...

journal_title：Neuroscience letters

authors： Sommer I,Schachner M

更新日期：1982-04-16 00:00:00

abstract：:Normal aging is associated with chronic oxidative stress. In the basal ganglia, oxidative stress may contribute to the increased risk of Parkinson's disease in the elderly. Neurons are thought to actively utilize compensatory defense mechanisms, such as heat shock proteins (HSPs), to protect from persisting stress. De...

journal_title：Neuroscience letters

authors： Gupte AA,Morris JK,Zhang H,Bomhoff GL,Geiger PC,Stanford JA

更新日期：2010-03-19 00:00:00

abstract：:RMI 12330A dose-dependently inhibits cAMP accumulation induced by PGE2 in guinea-pig superior cervical ganglion (SCG). Norepinephrine (NE) is unable to modify cAMP concentration in the same preparation. On the other hand, both PGE2 and NE block the firing discharge of guinea-pig SCG neurons elicited by electrical stim...

journal_title：Neuroscience letters

authors： Borasio PG,Ferretti ME,Biondi C,Trevisani A

更新日期：1982-10-08 00:00:00

abstract：:The potential neurotoxicity of the solvent toluene to the nigrostriatal dopaminergic system was assessed in a rat model of Parkinson's disease. Rats, 1 day after a unilateral injection of 6-hydroxydopamine (6-OH DA) into the substantia nigra, inhaled air or different concentrations of toluene (80, 300 or 1000 ppm), 6 ...

journal_title：Neuroscience letters

authors： Cintra A,Andbjer B,Finnman UB,Hagman M,Agnati LF,Höglund G,Fuxe K

更新日期：1996-10-11 00:00:00

abstract：:Field potentials were recorded with electrodes implanted in various cortical areas while a naive monkey was learning reaction time hand movements with complex tone. When cortical surface-negative, depth-positive potential (at a latency of about 80 ms after a stimulus onset) appeared in the rostral bank of the inferior...

journal_title：Neuroscience letters

authors： Gemba H,Miki N,Sasaki K

更新日期：1995-05-05 00:00:00

abstract：:In vivo formation of 1-methyl-4-phenylpyridinium ion (MPP(+)) in the striatum, and dopaminergic neurotoxicity following systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the presence and absence of calcium channel agonist (+/-)-Bay K8644 were analyzed in Balb/c mice. We used HPLC-photod...

journal_title：Neuroscience letters

authors： Samantaray S,Mohanakumar KP

更新日期：2003-07-31 00:00:00

abstract：:Adjacent serial sections of the organum vasculosum laminal terminalis (OVLT) of the rat were incubated with antisera of luteinizing-hormone--releasing-hormone (LH-RH) and somatostatin and stained by the peroxidase-antiperoxidase technique. The distribution patterns of the two oligopeptides show distinct differences, a...

journal_title：Neuroscience letters

authors： Krause R

更新日期：1979-02-01 00:00:00

abstract：:The paper focuses on such candidate gene polymorphisms that alter alcoholism-related intermediate phenotypes including: dopaminergic system polymorphic variants (DRD2 -141C Ins/Del in promoter region, exon 8 and DRD2 TaqI A and DAT 40bp VNTR genes polymorphisms) that cause predisposition to severe alcoholism (haplotyp...

journal_title：Neuroscience letters

authors： Samochowiec J,Kucharska-Mazur J,Grzywacz A,Jabłoński M,Rommelspacher H,Samochowiec A,Sznabowicz M,Horodnicki J,Sagan L,Pełka-Wysiecka J

更新日期：2006-12-13 00:00:00

abstract：:Experiments were performed to test several predictions of the hypothesis that activity pattern-dependent changes in intracellular free calcium concentration ([Ca2+]i) might play a role in the translation of altered patterns of neuronal activity into changes in neurotransmitter gene expression. It was shown that (1) th...

journal_title：Neuroscience letters

authors： Hodaie M,Jeevaratnam P,Salter MW,Roach A

更新日期：1995-02-13 00:00:00

abstract：:Accumulating evidence indicates that obesity is an independent risk factor for developing Alzheimer disease (AD). Recent studies have shown that diet-induced obesity (DIO) enhances AD-related pathologies in transgenic mouse models of the disease. DIO increases amyloid β (Aβ) deposition in amyloidogenic transgenic mice...

journal_title：Neuroscience letters

authors： Koga S,Kojima A,Kuwabara S,Yoshiyama Y

更新日期：2014-06-13 00:00:00

abstract：:Methylated beta-carboline compounds are mammalian indole metabolites that we have proposed to be endogenous neurotoxins due to their structural similarity to MPP+, the active oxidized product of the dopaminergic toxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Several laboratories have demonstrated that MPP...

journal_title：Neuroscience letters

authors： Neafsey EJ,Drucker G,Raikoff K,Collins MA

更新日期：1989-11-06 00:00:00

abstract：:The hypothesis that synaptic transmission between the auditory nerve and the cochlear nucleus is mediated by an excitatory amino acid acting through N-methyl-D-aspartate (NMDA) receptors was examined in an in vitro preparation of the chicken brainstem. The ability of various bath-applied excitatory amino acid receptor...

journal_title：Neuroscience letters

authors： Nemeth EF,Jackson H,Parks TN

更新日期：1983-09-19 00:00:00

abstract：:Using immunohistochemistry with specific antisera against dopamine-beta-hydroxylase and phenylethanolamine N-methyltransferase, we present the first description of the adrenergic structures of the sheep medulla oblongata. Dopamine-beta-hydroxylase-immunoreactive perikarya in the sheep brain are localized as described ...

journal_title：Neuroscience letters

authors： Tillet Y

更新日期：1988-12-19 00:00:00

abstract：:Muscle fatigue is known to be associated with a deteriorated muscle coordination and impaired movement performance in variety of voluntary movements. The aim of this study was to investigate the generally underexplored effect of muscle fatigue on both the coordination between grip force (GF; the force component perpen...

journal_title：Neuroscience letters

authors： Emge N,Prebeg G,Uygur M,Jaric S

更新日期：2013-08-29 00:00:00

abstract：:The morphology and function of sciatic nerve were investigated in spontaneously hypertensive rats (SHR), either control or hydralazine-treated, and in normotensive Wistar Kyoto rats of 6 months of age. In control SHR decreased percentages of class I fibers (20-15 microm in diameter), of axonal NFP-H 200 kDa neurofilam...

journal_title：Neuroscience letters

authors： Tomassoni D,Traini E,Vitaioli L,Amenta F

更新日期：2004-05-20 00:00:00

abstract：:Dibutyrylcytidine 3',5'-cyclic monophosphate (Bt2cCMP) stimulated neurite outgrowth in rat pheochromocytoma PC12 cells in a dose-dependent manner at the dose range from 0.5 mM to 6 mM. About 25% of the cells had neurites in response to 6 mM Bt2cCMP. In contrast with the effect of nerve growth factor (NGF) which increa...

journal_title：Neuroscience letters

authors： Yanagida M,Gohda E,Yamamoto I

更新日期：1990-07-13 00:00:00

abstract：:The activation of immature rat S1 neocortex by electrical stimulation of peripheral nerves and of the thalamus is described. The existence of a surface-positive potential of intracortical origin at an early stage of development is confirmed. It is also shown that both the augmenting and the recruiting phenomena can be...

journal_title：Neuroscience letters

authors： Verley R,Axelrad H

更新日期：1975-08-01 00:00:00

abstract：:Anti-Hu is an autoantibody that recognizes an antigen (Hu) highly restricted to neuronal nuclei. In the developing rat brain all neurons and the germinal cell layer were anti-Hu positive. Ependyma and choroid plexus were positive only in the early stages of development. The strongest expression of Hu was seen in the m...

journal_title：Neuroscience letters

authors： Graus F,Ferrer I

更新日期：1990-04-20 00:00:00