Abstract：
:Adjacent serial sections of the organum vasculosum laminal terminalis (OVLT) of the rat were incubated with antisera of luteinizing-hormone--releasing-hormone (LH-RH) and somatostatin and stained by the peroxidase-antiperoxidase technique. The distribution patterns of the two oligopeptides show distinct differences, as already found in the median eminence. A denser, more centrally placed somatostatin deposit is surrounded by a more extensive, looser, more peripheral one of LH0RH. These differences in distribution may reflect an anatomical basis for the differing effects of various manipulations on the OVLT and median eminence stores.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Krause Rdoi
10.1016/0304-3940(79)90123-xsubject
Has Abstractpub_date
1979-02-01 00:00:00pages
177-80issue
2eissn
0304-3940issn
1872-7972pii
0304-3940(79)90123-Xjournal_volume
11pub_type
杂志文章abstract：:By using a monoclonal antibody and polyclonal antibodies to human beta amyloid precursor protein (APP), we immunohistochemically examined axonal swellings (spheroids). The immunoreactivity of APP was observed in numerous spheroids, which were found around the areas of old cerebral infarctions, in the globus pallidus w...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(92)90651-m
更新日期：1992-02-17 00:00:00
abstract：:The effects of Ga-Al-As diode laser (830 nm, 16.2 mW) irradiation on the distal portion of the processes of cultured murine dorsal root ganglion (DRG) neurons associated with C-fibers were studied by patch-clamp whole-cell recording of membrane potentials at the cell body. The chemical as well as laser light stimulati...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(97)00935-x
更新日期：1998-01-09 00:00:00
abstract：:To better understand the pathophysiological role of Src protein, a non-receptor protein tyrosine kinase of 60kDa, in the ischemic brain, we investigated the time course and regional distribution of active Src expression by using a specific antibody against Tyr416 phosphorylated Src (phospho-Src) in the rat hippocampus...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2005.01.015
更新日期：2005-05-20 00:00:00
abstract：:This study examines the effect of acetylcholine (Ach) on parasympathetic vagal neurons in the dorsal motor nucleus of the vagus (DMNX). Patch-clamp techniques were utilized to examine voltage and ligand-gated currents in visualized DMNX neurons in an in vitro slice. Ach (100 microM) activated an inward current, -196.4...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(95)11807-9
更新日期：1995-08-11 00:00:00
abstract：:Tacrine (1,2,3,4-tetrahydro-9-acridinamine) inhibited binding of [3H]flunitrazepam to benzodiazepine receptors of guinea pig hippocampus with an inhibition constant of 46 microM at 2 degrees C and 37 degrees C. gamma-Aminobutyric acid (GABA) decreased the affinity of tacrine for the receptor, suggesting that tacrine m...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90473-7
更新日期：1991-08-19 00:00:00
abstract：:Recently, we have reported that erythropoietin (Epo) provides neuroprotection in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-induced neurotoxicity in vivo. In the present study, we investigated the effects of single Epo administration on brain antioxidant enzyme (superoxide dismutase (SOD) and glutathion perox...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(02)00041-1
更新日期：2002-03-15 00:00:00
abstract：:In decerebrate cats, intracellular recordings were made in 124 expiratory neurons displaying either a plateau-phase of depolarization during post-inspiration or a steadily decrementing depolarization throughout expiration. Both groups consisted of vagal motoneurons and non-antidromically activated neurons. Five neuron...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(93)90779-k
更新日期：1993-01-12 00:00:00
abstract：:In the present study we investigated the effect of electrolytic lesion of the medial septal area (MSA) on the dipsogenic, natriuretic, kaliuretic and pressor responses elicited by intracerebroventricular (i.c.v.) injection of the cholinergic agonist carbachol. Freely moving rats with sham or MSA lesion (1-7 days and 1...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90300-i
更新日期：1991-11-11 00:00:00
abstract：:Rat myotubes were cultured with embryonic mouse spinal cord explants. After 4 days of co-culture, (miniature) endplate potentials, (M)EPPs, could be detected in 20-40% of the nerve-contacted myotubes. Polyclonal antibodies against the neural cell adhesion molecule N-CAM and monoclonal antibodies to its L2/HNK-1 carboh...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(87)90368-5
更新日期：1987-08-05 00:00:00
abstract：:Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine involved in the development and maintenance of inflammatory and neuropathic pain conditions. The mechanisms by which TNF-alpha elicits pain behavior are still incompletely understood. Numerous studies suggest that TNF-alpha sensitizes primary affere...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.01.070
更新日期：2008-04-04 00:00:00
abstract：:Attention-deficit/hyperactivity disorder (ADHD) is highly prevalent in children and adolescents and both environmental and genetic factors play major roles. Polyunsaturated fatty acids (PUFAs) are postulated to contribute to the development of the infant brain and an imbalance in these may increase the risk of ADHD. I...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2013.11.023
更新日期：2014-01-24 00:00:00
abstract：:Epigallocatechin-3-gallate (EGCG) is a powerful antioxidant with suggested neuroprotective action. This study investigated the protective effects of EGCG against retinal ganglion cells (RGCs) degeneration in an animal model of glaucoma. C57BL/6J mice (n=54) were divided randomly into four groups: normal control group ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2015.06.002
更新日期：2015-07-23 00:00:00
abstract：:In human caudate and cortex membranes, [3H]serotonin ([3H]5-HT) labels 5-HT1A and 5-HT1C recognition sites which show nanomolar affinity for 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)-tetralin) and mesulergine respectively, whereas no 5-HT1B binding could be identified. However, the majority of the sites labelled by [3...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(88)90592-7
更新日期：1988-03-10 00:00:00
abstract：:In gastropods, the interneuronal messenger, nitric oxide (NO), modulates spike frequency and synaptic transmission. We have characterized the effect of NO on ion currents underlying neuronal excitability, using current-clamp and two-electrode voltage-clamp techniques. Identified neurons of the pulmonate snail, Helix p...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(00)01606-2
更新日期：2000-12-08 00:00:00
abstract：:Research indicates that threat-induced changes in standing balance are associated with shifts in attention focus. This study investigated whether distracting attention modifies threat-induced changes in standing balance. Twenty-five healthy young adults stood without (No Threat) and with (Threat) the possibility of re...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2019.134635
更新日期：2020-01-18 00:00:00
abstract：:A new non-N-methyl-D-aspartate (non-NMDA) glutamate receptor antagonist, GYKI 52466, was tested on L-glutamate (Glu)-, kainate (KAI)- and NMDA-induced responses in vivo, using both extracellular recording of antidromic field potentials and intracellular recording from rat abducens motoneurones. Intravenous (5-10 mg/kg...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90115-a
更新日期：1991-04-15 00:00:00
abstract：:Disturbed motor control of the fingers, as revealed by the response to unexpected loading of an object held in a precision grip, or to finger perturbation during isometric holding, has been studied in patients with Huntington's disease (HD) and in normal subjects. In normal subjects unexpected loading elicited a refle...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(97)00264-4
更新日期：1997-04-25 00:00:00
abstract：:The effects of micro-electrophoretically applied melatonin on the electrical activity of Purkinje cells in the cerebellum of anaesthetized pigeons were studied. The proportion of excitatory and inhibitory responses to the pineal indoleamine varied significantly depending on whether the cells were tested during the day...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(86)90072-8
更新日期：1986-12-12 00:00:00
abstract：:We have recently shown that the cytoplasmic tail of the somatostatin receptor sst2 undergoes alternative splicing giving rise to two isoforms, SSt2A and sst2B. In the present study, we have raised polyclonal antibodies that specifically detect either sst2A or sst2B and used these antisera for immunocytochemical locali...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(98)00803-9
更新日期：1998-11-20 00:00:00
abstract：:To investigate the contribution of nigral degeneration to the development of parkinsonism in the early stages of corticobasal degeneration (CBD), we measured the cerebrospinal fluid (CSF) levels of homovanillic acid (HVA) in patients with early CBD (n = 5), and compared the levels with those in patients with early Par...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(98)00181-5
更新日期：1998-04-03 00:00:00
abstract：:Event-related potentials were recorded from sleeping newborns to compare amplitudes and latencies of mismatch negativity (MMN) and late discriminative negativity (LDN) in active and quiet sleep stages. MMN and LDN were obtained in response to changes in semi-synthesized vowels from 20 healthy newborn infants. MMN and ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(02)01401-5
更新日期：2003-04-10 00:00:00
abstract：:Statins are lipid-lowering drugs that have been shown to reduce atherosclerotic cardiovascular morbidity and mortality. However, there is growing evidence from epidemiological studies that long-term treatment with statins has unwanted effects on extrahepatic tissue and increases the risk for neuropathy. To investigate...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2003.10.022
更新日期：2004-01-23 00:00:00
abstract：:The present study was performed to explore the role of galanin in nociceptive modulation in anterior cingulate cortex (ACC) of rats with acute inflammation, and the changes in galanin and galanin receptor 2 (Gal R2) expressions in rats with acute inflammation. Intra-ACC injection of galanin induced antinociception in ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2016.12.034
更新日期：2017-01-18 00:00:00
abstract：:We observed the changes of body temperature and the cytokine expressions in the hypothalamus of rats to investigate the effect and mechanism of antipyretic action of acupuncture. Lipopolysaccharide (LPS, i.p., 2.5 mg/kg) was injected into rats and manual acupuncture was performed on Shaofu (HT8), Zutonggu (BL66) or Xi...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(01)02538-1
更新日期：2002-02-08 00:00:00
abstract：:The specific mRNA of myelin basic protein (MBP) was isolated from active myelinating rat brains. The isolated mRNA was able to direct the synthesis of immunochemically detectable MBP in a wheat-germ cell free protein synthesis system. There was, however, no evidence of neuronal translational control of the in vitro MB...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(82)90370-6
更新日期：1982-03-17 00:00:00
abstract：:This study used magnetoencephalography (MEG) to examine the dynamic patterns of neural activity underlying the auditory steady-state response. We examined the continuous time-series of responses to a 32-Hz amplitude modulation. Fluctuations in the amplitude of the evoked response were found to be mediated by non-linea...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2005.05.043
更新日期：2005-09-16 00:00:00
abstract：:The aim of the present study was to investigate the moderating effect of intolerance of uncertainty (IU) on exposure to aversion and its anticipation using event-related potentials (ERPs). Sixteen subjects high in IU and 16 subjects low in IU underwent an affective cueing paradigm where a warning cue signaled the vale...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.11.054
更新日期：2012-01-24 00:00:00
abstract：:Since the rubro-olivary projection has not been demonstrated in the rat, unlike the monkey and cat (refs. in text). HRP or highly-concentrated wheat germ agglutinin-horseradish peroxidase (WGA-HRP) was injected into the inferior olivary nucleus using a ventral approach. After processing with a modified technique, sect...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(87)90307-7
更新日期：1987-03-09 00:00:00
abstract：:Mild cognitive impairment (MCI) is characterized by cognitive deficits which do not yet reach the threshold of dementia but represent a putative preclinical state of Alzheimer's disease (AD). Little is known about the neural correlates of delayed episodic memory which is among the earliest signs of cognitive decline i...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2009.10.014
更新日期：2009-12-25 00:00:00
abstract：:Down syndrome is the most common genetic cause of intellectual disability and occurs due to the trisomy of human chromosome 21. Adolescent and adult brains from humans with Down syndrome exhibit various neurological phenotypes including a reduction in the size of the corpus callosum, hippocampal commissure and anterio...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2019.134569
更新日期：2020-01-01 00:00:00
