Capsaicin sensitive afferents mediate the development of heat hyperalgesia and hindpaw edema after sciatic section in rats.

abstract：:Event-related brain potentials were recorded from healthy human subjects while they attended to one of two auditory stimulus channels (defined by location, left and right of a fixation point, and pitch) in order to detect rare target events. The distracting properties of periodic noise (vs. continuous noise, experimen...

journal_title：Neuroscience letters

authors： Nager W,Rosenthal O,Bohrer I,Teder-Sälejärvi WA,Münte TF

更新日期：2001-01-05 00:00:00

abstract：:In vitro pituitary adenylate cyclase activating polypeptide (PACAP) induces the expression of brain-derived neurotrophic factor (BDNF) via its specific receptor PAC1. Since BDNF has been implicated in learning paradigms and mice lacking functional PAC1 have deficits in hippocampus-dependent associative learning, we in...

journal_title：Neuroscience letters

authors： Zink M,Otto C,Zörner B,Zacher C,Schütz G,Henn FA,Gass P

更新日期：2004-04-22 00:00:00

abstract：:The effect of nitric oxide donor compounds (sodium nitroprusside, hydroxylamine and S-nitroso-N-acetyl-D,L-penicillamine) on depolarization-induced release of endogenous dopamine in the light-adapted, isolated retina of the rabbit was studied by HPLC. All three compounds had the same effect, reducing the amount of dop...

journal_title：Neuroscience letters

authors： Djamgoz MB,Cunningham JR,Davenport SL,Neal MJ

更新日期：1995-09-22 00:00:00

abstract：:Following unilateral transection of the medial forebrain bundle (MFB) within the anterior hypothalamic-preoptic region of cats, the biting attack upon a rat elicited by ipsilateral posterior hypothalamic or ventral midbrain stimulation is eliminated, although the cat continues to approach from 2.8 metres away to withi...

journal_title：Neuroscience letters

authors： Halliday R,Bandler R

更新日期：1981-01-20 00:00:00

abstract：:Low doses of colchicine (greater than 0.5 microgram) injected into the eyes of young chickens irreversibly inhibit axonal transport of material labelled with [3H]fucose. This is due to almost total destruction of the retinal ganglion cells, while other retinal cell types, including the displaced amacrine cells found i...

journal_title：Neuroscience letters

authors： Morgan IG

更新日期：1981-07-17 00:00:00

abstract：:Intolerance of uncertainty (IU), or the increased affective response to situations with uncertain outcomes, is an important component process of anxiety disorders. Increased IU is observed in panic disorder (PD), obsessive compulsive disorder (OCD) and generalized anxiety disorder (GAD), and is thought to relate to dy...

journal_title：Neuroscience letters

authors： Simmons A,Matthews SC,Paulus MP,Stein MB

更新日期：2008-01-10 00:00:00

abstract：:The analgesic effect of kappa partial agonist opioids (i.e. nalbuphine, pentazocine and butorphanol) is significantly greater in women. Recent evidence suggests that this sexual dimorphism may result from a naloxone-sensitive anti-analgesic effect that is activated along with, and summates with, the analgesic effect o...

journal_title：Neuroscience letters

authors： Gear RW,Gordon NC,Miaskowski C,Paul SM,Heller PH,Levine JD

更新日期：2003-11-06 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH) plays an important role in the regulation of energy balance. While the regulation of TRH in the paraventricular nucleus (PVN) in response to changes of energy balance has been well studied, how TRH is regulated in the dorsomedial hypothalamus (DMH) in maintaining energy homeostasis ...

journal_title：Neuroscience letters

authors： Zhang N,Zhang HY,Bi SA,Moran TH,Bi S

更新日期：2019-06-11 00:00:00

abstract：:The neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal total biopterin were examined both in rats and mice at different time courses. Results indicate that MPTP caused a significant decrease of total biopterin content in the striatum of mice. This effect occurred as soon as 6 h after...

journal_title：Neuroscience letters

authors： Lee EH

更新日期：1988-06-07 00:00:00

abstract：:During neuronal development, the neuroepithelial stem cells (NSCs) initially undergo proliferative divisions, later switching to neurogenic ones whereby one NSC and a post-mitotic neuron are generated. We recently showed that a member of the PRDM family of transcriptional regulators, PRDM4/SC1, recruits a type II prot...

journal_title：Neuroscience letters

authors： Chittka A

更新日期：2013-08-29 00:00:00

abstract：:The aim of the study was to investigate the characteristics of the oscillatory dynamics of brain activity during the perception of negative, positive, and neutral sentences in healthy individuals with differing severity of depressive symptoms at the preclinical stage. The study involved 34 healthy people (22 women). T...

journal_title：Neuroscience letters

authors： Bocharov AV,Savostyanov AN,Tamozhnikov SS,Merkulova EA,Saprigyn AE,Proshina EA,Knyazev GG

更新日期：2020-05-29 00:00:00

abstract：:There is evidence indicating that the brain's dopaminergic system is involved in age-associated memory impairment. However, specific roles in this process for the different dopamine receptor subtypes have not been elucidated. The cAMP-response element binding protein (CREB) is one of the cellular molecules that have b...

journal_title：Neuroscience letters

authors： Xing B,Meng X,Wei S,Li S

更新日期：2010-09-13 00:00:00

abstract：:This study examined the effects of exposure to low concentrations (0.1-100 nM) of bisphenol A (BPA) or nonylphenol (NP) on neuronal differentiation in pheochromocytoma PC12 cells. Pre-exposure to BPA for a week or a month, but not for a day, decreased neuronal differentiation in PC12 cells. Likewise, one week's pre-ex...

journal_title：Neuroscience letters

authors： Nishimura Y,Nagao T,Fukushima N

更新日期：2014-06-06 00:00:00

abstract：:In the present study we have used slice cultures of hippocampus and in situ hybridization techniques in order to study the ability of hippocampal neurons to synthesize CCK mRNA in the absence of extrinsic afferents. Our results show that very similar types of hippocampal neurons express CCK mRNA in culture as in situ....

journal_title：Neuroscience letters

authors： Straube A,Bender R,Otten U,Frotscher M

更新日期：1994-05-19 00:00:00

abstract：:Hyperacusis may be defined as diminishing tolerance to moderate and high intensity sounds in people with normal hearing sensitivity. Serotonin plays a critical role in some of auditory tasks including startle reflex and prepulse inhibition. Serotonin deficiency can cause some diseases which can coincide with hyperacus...

journal_title：Neuroscience letters

authors： Farahani S,Nasirinezhad F,Danyali S,Jalaei S,Shahbazi A,Karimi M,Mokrian H

更新日期：2019-07-13 00:00:00

abstract：:The single channel properties of four P2X receptors heterologously expressed in Chinese hamster ovary cells were determined from outside-out patch recordings. P2X1 and P2X4 channels opened in brief flickery bursts with conductances of approximately 18 and 9 pS respectively. P2X2 receptors had a single channel conducta...

journal_title：Neuroscience letters

authors： Evans RJ

更新日期：1996-07-19 00:00:00

abstract：:Contact heat evoked potentials (CHEPs) have been difficult to elicit due to slow temperature rise times. A recently developed heat-foil technology was used to elicit pain and CHEPs. Two groups of subjects were separately stimulated at the left arm with contact heat via one fast-acting (70 degrees C/s) heat-foil thermo...

journal_title：Neuroscience letters

authors： Chen AC,Niddam DM,Arendt-Nielsen L

更新日期：2001-12-01 00:00:00

abstract：:Convulsions were induced in rats by a single injection of pentylenetetrazol (PTZ) and [3H]L-2-amino-4-phosphonobutyrate ([3H]L-AP4) in vitro receptor autoradiography was used to evaluate the effects on the expression of group III metabotropic glutamate receptors. Significant increases by 60-80% in [3H]L-AP4 binding wa...

journal_title：Neuroscience letters

authors： Thomsen C

更新日期：1999-04-30 00:00:00

abstract：:RGS (regulators of G protein signaling) proteins negatively regulate the alpha subunit of G proteins by accelerating their intrinsic GTPase activity. In a previous work, we reported the cloning of a cDNA encoding for a new RGS protein, RET-RGS. We showed that it is specifically expressed in the retina, notably by phot...

journal_title：Neuroscience letters

authors： Faurobert E,Scotti A,Hurley JB,Chabre M

更新日期：1999-07-02 00:00:00

abstract：:The bradykinin B2 receptor (B2R) mediates many physiological processes such as hypotension, inflammation and blood-vessel permeability. Hypoxia/reoxygenation (H/R) induces neuronal cell apoptosis. It was found that B2R expression was enhanced in primary cultured cortical neurons after H/R treatment. Addition of bradyk...

journal_title：Neuroscience letters

authors： Tang M,Cui M,Dong Q,Ren HM,Xiao BG,Luo BY,Shao Y,Liu L,Zhou HG

更新日期：2009-01-23 00:00:00

abstract：:It has been shown that the incidence of cognitive impairment increases with the severity of chronic kidney disease (CKD). A previous study has demonstrated that hippocampal oxidative stress contributes to cognitive dysfunction in CKD model mice. Endoplasmic reticulum (ER) stress is thought to contribute significantly ...

journal_title：Neuroscience letters

authors： Kosuge Y,Osada N,Shimomura A,Miyagishi H,Wada T,Ishige K,Shimba S,Ito Y

更新日期：2018-06-11 00:00:00

abstract：:We have conjectured that axons embody a post transcriptional sprouting programme repressed by mature Schwann cells. Injured nerves of Wld(s) mice neither degenerate nor regenerate for several weeks but axons do regrow if the resident cells of the distal stump are destroyed. To test our hypothesis we made an extended c...

journal_title：Neuroscience letters

authors： Iñiguez A,Alvarez J

更新日期：1999-06-18 00:00:00

abstract：:The activity of single units in the striatum of urethane-anesthetized rats was recorded before and after the systemic administration of 7-nitro-indazole (7-NI; 50 mg/kg intraperitoneally), a selective inhibitor of neuronal nitric oxide (NO) synthase. Two neuronal types were clearly distinguishable electrophysiological...

journal_title：Neuroscience letters

authors： Sardo P,Ferraro G,Di Giovanni G,Galati S,La Grutta V

更新日期：2002-06-14 00:00:00

abstract：:Extracellular dopamine and noradrenaline concentrations in the medial prefrontal cortex were determined using online microdialysis in freely moving rats during classical appetitive or aversive conditioning to a contextual conditioned stimulus (CS). As CS we used placement in a Skinner box where either foot shocks or f...

journal_title：Neuroscience letters

authors： Feenstra MG,Teske G,Botterblom MH,De Bruin JP

更新日期：1999-09-17 00:00:00

abstract：:Lead is a neurotoxicant of immense public health importance. Epidemiology studies suggest that heavy metal exposure may be associated with an increased risk of cognitive decline, yet few studies to date have assessed the effect of adult lead exposure on cognitive behavior in animal models. Here, we exposed 6-week-old ...

journal_title：Neuroscience letters

authors： Engstrom AK,Xia Z

更新日期：2017-11-20 00:00:00

abstract：:Crickets (Gryllus bimaculatus) use the cercal sensory system at the rear of the abdomen to detect air currents and direct predator avoidance behavior. Sensory information regarding the direction and dynamic properties of air currents is processed within the terminal abdominal ganglion, and conveyed by ascending giant ...

journal_title：Neuroscience letters

authors： Ogawa H,Kajita Y

更新日期：2015-01-01 00:00:00

abstract：:In mammals, methyl-CpG binding proteins play a significant role in the control of gene expression through their association with chromatin-remodeling complexes. Mutations in the gene coding for methyl-CpG-binding protein 2 (MECP2) cause Rett syndrome and have also been reported in a number of X-linked mental retardati...

journal_title：Neuroscience letters

authors： dos Santos JM,Abdalla CB,Campos M Jr,Santos-Rebouças CB,Pimentel MM

更新日期：2005-04-29 00:00:00

abstract：:Previous studies showed egocentric but not allocentric mental rotation tasks to be impaired in microgravity when feedback cues about vertical surroundings were restricted. Those studies are difficult to reconcile, however, since they were limited not only to small subject groups, but also differed dramatically in desi...

journal_title：Neuroscience letters

authors： Dalecki M,Dern S,Steinberg F

更新日期：2013-01-15 00:00:00

abstract：:We recently showed that dopamine (DA) and serotonin (5-HT) exert anticonvulsant effects against limbic seizures in rats mediated by hippocampal D(2) and 5-HT(1A) receptor stimulation. For exogenously administered monoamines, anticonvulsant activity was only observed following 70--400% and 80--350% increases in baselin...

journal_title：Neuroscience letters

authors： Clinckers R,Smolders I,Meurs A,Ebinger G,Michotte Y

更新日期：2005-12-16 00:00:00

abstract：:Confocal immunohistochemistry shows that neurotrophin-3 (NT-3) and its receptor tropomyosin-related tyrosin kinase C (trkC) are present in both neonatal (P6) and adult (P45) mouse motor nerve terminals in neuromuscular junctions (NMJ) colocalized with several synaptic proteins. NT-3 incubation (1-3h, in the range 10-2...

journal_title：Neuroscience letters

authors： Garcia N,Santafé MM,Tomàs M,Lanuza MA,Besalduch N,Tomàs J

更新日期：2010-04-05 00:00:00