Hippocampal dopamine and serotonin elevations as pharmacodynamic markers for the anticonvulsant efficacy of oxcarbazepine and 10,11-dihydro-10-hydroxycarbamazepine.

abstract：:When a tone-burst train with a short inter-burst interval is lateralized to the left and is followed by another tone-burst train lateralized to the right, listeners report a smooth shift of tone bursts along the intracranial axis from left to right (known as auditory saltation). When a sequence of tone bursts with a c...

journal_title：Neuroscience letters

authors： Kawabe T

更新日期：2010-01-14 00:00:00

abstract：:Capsaicin, a neurotoxin which impairs some primary afferent nerve fibers, was locally applied to the mesenteric nerve trunks of adult guinea pigs. The effect of capsaicin was studied on contractile responses of the ileum to mesenteric nerve stimulation (20 Hz). Exposure of the mesenteric nerve to capsaicin (1 microM) ...

journal_title：Neuroscience letters

authors： Jin JG,Takaki M,Nakayama S

更新日期：1989-11-20 00:00:00

abstract：:Intracellular recordings were made of neurons in the myenteric plexus of the guinea-pig distal ileum. Slow excitatory postsynaptic potentials (sEPSPs) were evoked by electrical stimulation of an interganglionic fibre tract. The effect of cholecystokinin (CCK) receptor antagonists on the sEPSPs was investigated in 11 n...

journal_title：Neuroscience letters

authors： Schutte IW,Hollestein KB,Akkermans LM,Kroese AB

更新日期：1997-11-07 00:00:00

abstract：:Ideomotor theory states that the neural codes that represent action and the perceptual consequences of those actions are tightly bound in a common code. For action imagination, bound action, and perceptual codes are thought to be internally activated at a sub-threshold level through action simulation. In support of th...

journal_title：Neuroscience letters

authors： Yoxon E,Tremblay L,Welsh TN

更新日期：2015-01-12 00:00:00

abstract：:High K+ (50 mM) increased both [3H]acetylcholine ([3H]ACh) release and cytosolic free calcium level ([Ca2+]i) in rat brain synaptosomes in the presence of extracellular Ca2+. Ouabain (5 x 10(-8) to 5 x 10(-4) M) also caused a dose-dependent increase in [3H]ACh release, but not in [Ca2+]i, in the absence of Ca2+. The e...

journal_title：Neuroscience letters

authors： Satoh E,Nakazato Y

更新日期：1989-12-15 00:00:00

abstract：:The development of supersensitivity to dopamine by striatal neurons is widely considered to be a response to interruption of dopaminergic synaptic function. However, it is not clear whether pre-existing dopaminergic innervation is in fact necessary for supersensitivity to develop. In this study, rat foetal striatal ce...

journal_title：Neuroscience letters

authors： Guerra MJ,Liste I,Rozas G,Tobio J,Labandeira-Garcia JL

更新日期：1996-03-15 00:00:00

abstract：:In rats, immunoreactivity was demonstrated in the brush border of the choroid plexus, in the wall of blood vessels in the brain, and in the brush border of the proximal tubules of the kidney, using the peroxidase-antiperoxidase technique (PAP) and an anti-pulmonary converting-enzyme antibody. These findings correlate ...

journal_title：Neuroscience letters

authors： Rix E,Ganten D,Schüll B,Unger T,Taugner R

更新日期：1981-03-10 00:00:00

abstract：:It has been shown that orexin neuropeptides contribute to morphine-induced physical dependence. The locus coeruleus (LC), which receives a dense extra-hypothalamic orexinergic projection, is a key brain region implicated in the expression of somatic signs of morphine withdrawal syndrome. The aim of the present study i...

journal_title：Neuroscience letters

authors： Azizi H,Mirnajafi-Zadeh J,Rohampour K,Semnanian S

更新日期：2010-10-04 00:00:00

abstract：:The regulation of blood glucose level in intracerebroventricular (i.c.v.) administration with opioid alone or opioid withdrawal model was studied in ICR mice. In the first group, we found that i.c.v. administered morphine or beta-endorphin alone causes an elevation of blood glucose level. Blood glucose level induced b...

journal_title：Neuroscience letters

authors： Park SH,Sim YB,Kang YJ,Kim SM,Lee JK,Jung JS,Suh HW

更新日期：2010-06-07 00:00:00

abstract：:We immunohistochemically investigated the degeneration processes of the nigro-striatal and nigro-amygdaloid pathways and the relationship between the loss of dopaminergic neurons and Lewy bodies (LB) formation in the substantia nigra using 15 autopsied cases of dementia with Lewy bodies (DLB). The number of tyrosine h...

journal_title：Neuroscience letters

authors： Iseki E,Marui W,Yamamoto R,Togo T,Katsuse O,Kato M,Iwatsubo T,Kosaka K,Arai H

更新日期：2005-05-20 00:00:00

abstract：:Epileptiform activity is a state often induced in vitro in order to study seizures and antiepileptic/anticonvulsant drugs. Traditional methods of evaluating drug effects have commonly relied upon measuring changes in the frequency and duration of such events. We have used a recently developed mathematical technique ba...

journal_title：Neuroscience letters

authors： Harrison PK,Tattersall JE,Clement RA

更新日期：2004-03-11 00:00:00

abstract：:The cerebral vessels have sympathetic, parasympathetic, and sensory innervations. A sensory innervation of the cerebral vessels originating in the trigeminal ganglion has been described in a number of species by several investigations. It has been shown that the electrical stimulation of the trigeminal ganglion causes...

journal_title：Neuroscience letters

authors： Gürelik M,Karadağ O,Polat S,Ozüm U,Aslan A,Gürelik B,Göksel HM

更新日期：2004-07-29 00:00:00

abstract：:The present study seeked to determine whether the neurodegenerative and cognitive alterations in aged apolipoprotein E-deficient mice are differentially reversed by transgenic overexpression of human apolipoprotein-E3 vs. apolipoprotein-E4 in the background of deficient endogenous apolipoprotein E. These studies showe...

journal_title：Neuroscience letters

authors： Veinbergs I,Mallory M,Mante M,Rockenstein E,Gilbert JR,Masliah E

更新日期：1999-04-23 00:00:00

abstract：:Whole-cell patch-clamp recordings (WCR) were made from sympathetic preganglionic neurons (SPN) in neonate rat spinal cord slices. SPN were identified histologically by filling them with the fluorescent dye Lucifer Yellow contained within the patch pipette solution. Current clamp recordings were obtained from SPN with ...

journal_title：Neuroscience letters

authors： Pickering AE,Spanswick D,Logan SD

更新日期：1991-09-16 00:00:00

abstract：:The present study was undertaken to investigate whether benzodiazepine receptors are involved in either the anticonvulsant activity of phenytoin against supramaximal seizures or maximal threshold seizures induced by electroshock or the neurotoxicity of phenytoin. Ro 15-1788, a benzodiazepine receptor antagonist, rever...

journal_title：Neuroscience letters

authors： Chweh AY,Swinyard EA,Wolf HH

更新日期：1985-06-24 00:00:00

abstract：:Acetylcholinesterase (AChE) colocalizes with amyloid-beta peptide (A beta) deposits present in the brain of Alzheimer's patients. Recent studies showed that A beta 1-40 can adopt two different conformational states in solution (an amyloidogenic conformer, A beta ac, and a non-amyloidogenic conformer, A beta nac) which...

journal_title：Neuroscience letters

authors： Alvarez A,Bronfman F,Pérez CA,Vicente M,Garrido J,Inestrosa NC

更新日期：1995-12-01 00:00:00

abstract：:We investigated whether the perceived roughness of the end of a tool is influenced by the texture of the handle used to hold it. Participants rated the roughness of the ends (caps) of a series of tools by rubbing them along their forearm, and indicated the perceived roughness of the tool's cap by means of an anchored ...

journal_title：Neuroscience letters

authors： Zampini M,Mawhinney S,Spence C

更新日期：2006-06-12 00:00:00

abstract：:Pineal serotonin (5-HT), 5-hydroxyindole-acetic acid (5-HIAA), norepinephrine (NE), epinephrine (E) and adrenal corticosterone, NE and E contents were measured spectrofluorometrically 5, 15, 30 and 60 min after insulin treatment to induce hypoglycemic stress. In the pineal gland, hypoglycemic stress caused dramatic de...

journal_title：Neuroscience letters

authors： Mahata SK

更新日期：1991-01-02 00:00:00

abstract：:Pain consists of sensory and negative affective components. Using a conditioned place aversion (CPA) paradigm, we investigated whether the medial thalamus (MT) played a role in the affective component of visceral pain induced by intraperitoneal injection of acetic acid into male Long-Evan rats. Acetic acid produced wr...

journal_title：Neuroscience letters

authors： Wang HC,Chai SC,Wu YS,Wang CC

更新日期：2007-06-08 00:00:00

abstract：:Numerous studies have provided evidence that physical activity promotes cortical plasticity in the adult brain and in turn facilitates learning. However, until now, the effect of simultaneous physical activity (e.g. bicycling) on learning performance has not been investigated systematically. The current study aims at ...

journal_title：Neuroscience letters

authors： Schmidt-Kassow M,Kulka A,Gunter TC,Rothermich K,Kotz SA

更新日期：2010-09-20 00:00:00

abstract：:Rats were injected (i.p.) once daily with either 1 mg/kg CGP 56999A, a gamma-aminobutyric acid(B) (GABA(B)) receptor antagonist, or an equivalent volume of saline beginning 7 days prior to, and continuing for 7 days following, a unilateral 6-hydroxydopamine lesion of the nigrostriatal dopamine (DA) pathway. At the end...

journal_title：Neuroscience letters

authors： Enna SJ,Reisman SA,Stanford JA

更新日期：2006-10-02 00:00:00

abstract：:In this study, the notion of additivity in perception of affect from limb motion is investigated. Specifically, we examine whether the impact of multiple limbs in perception of affect is equal to the sum of the impacts of each individual limb. Several neutral, happy, and sad walking sequences are first aligned and ave...

journal_title：Neuroscience letters

authors： Etemad SA,Arya A,Parush A

更新日期：2014-01-13 00:00:00

abstract：:To determine the role of cytokines in the nervous system, we examined the effect of interleukin-12(IL-12) on the nerve regeneration of mouse superior cervical ganglion cells (SCG). IL-12 enhanced the neurite outgrowth in a concentration-dependent manner. Immunocytochemical studies demonstrated the expression of IL-12 ...

journal_title：Neuroscience letters

authors： Lin H,Hikawa N,Takenaka T,Ishikawa Y

更新日期：2000-01-14 00:00:00

abstract：:Neuron production carries on throughout adult life in granule cell layer of mammalian dentate gyrus. The acquisition of a hippocampus-dependent task enhances newborn cell survival in granule cell layer (GCL) during the period in which several newborn cells die. In this paper the effect of learning, occurring after the...

journal_title：Neuroscience letters

authors： Ambrogini P,Orsini L,Mancini C,Ferri P,Ciaroni S,Cuppini R

更新日期：2004-04-08 00:00:00

abstract：:To isolate the footedness contribution from the hemispheric visual asymmetry contribution to the upright postural control, seven right and six left-footed healthy women were asked to balance on each unipodal stance on an unstable platform for each visual hemispaces. We compared lateral deviations of the centre of pres...

journal_title：Neuroscience letters

authors： Golomer E,Mbongo F

更新日期：2004-09-02 00:00:00

abstract：:Free radical generation and release from the cerebral hemispheres of rats subjected to four-vessel occlusion elicited cerebral ischemia/reperfusion was monitored using a cortical cup technique with the spin-trapping agent alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone (POBN). Electron spin resonance (ESR) was used to d...

journal_title：Neuroscience letters

authors： Phillis JW,Sen S,Cao X

更新日期：1994-03-14 00:00:00

abstract：:Pyramidal neurons in the mammalian cerebral cortex can be described by a fractal dimension (Mandelbrot, 1982), which is an objective, quantitative measure of the complexity of their soma/dendritic borders. In the cat, the fractal dimensions of lamina V cells, which include pyramidal tract neurons (PTN), indicate that ...

journal_title：Neuroscience letters

authors： Porter R,Ghosh S,Lange GD,Smith TG Jr

更新日期：1991-09-02 00:00:00

abstract：:Electrophysiological differences between the shell and core of the rat nucleus accumbens were investigated by intracellular recordings from an in vitro slice preparation. The average input resistance of neurons recorded in the shell was larger than in the core. Neurons in the core were characterized by a more negative...

journal_title：Neuroscience letters

authors： Pennartz CM,Dolleman-Van der Weel MJ,Lopes da Silva FH

更新日期：1992-02-17 00:00:00

abstract：:Systemic administration of S18986, a positive allosteric modulator of AMPA receptors, improves cognition. The present study further characterizes the drug's memory-enhancing properties and is the first to investigate its intracerebral effects on learning and memory. The results showed that rats receiving a single dose...

journal_title：Neuroscience letters

authors： Yefimenko N,Portero-Tresserra M,Martí-Nicolovius M,Guillazo-Blanch G,Vale-Martínez A

更新日期：2013-08-26 00:00:00

abstract：:Autism spectrum disorder (ASD) is a group of developmental disorders characterized by social interaction deficits, communication impairments, and stereotyped and repetitive behaviors. Additionally, impairments in the GABAergic circuitry have been associated with ASD. Several studies have shown that dysfunction of the ...

journal_title：Neuroscience letters

authors： Varman DR,Soria-Ortíz MB,Martínez-Torres A,Reyes-Haro D

更新日期：2018-11-20 00:00:00